LEKOKLAR suspension 250 mg. 5 ml. 60 ml

LEKOKLAR suspension 250 mg. 5 ml. 60 ml
€ 23.00
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Clarithromycin is an antibiotic that belongs to the group of macrolide antibiotics. They stop the growth of certain bacteria.

LEKOKLAR suspension 250 mg. / 5 ml. 60 ml

What Lekoklar and what it is used

Clarithromycin is an antibiotic that belongs to the group of macrolide antibiotics. They stop the growth of certain bacteria.
Lekoklar is used to treat:
 infections of the throat and sinuses;
 middle ear infections in children;
 infections in the chest like bronchitis and pneumonia;
 infections of skin and soft tissue;
 stomach ulcers caused by the bacterium Helicobacter pyroli.

 Before you take Lekoklar


Do not take Lekoklar
 if you are allergic (hypersensitive) to clarithromycin, other macrolide antibiotics or to any of the excipients Lekoklar (see more details in Section 6);
 if you have a history of certain heart rhythm (ventricular arrhythmias, including torsades de pointes) or changes in heart rate, measured in an electrocardiogram called "QT prolongation"
 If you suffer from severe liver failure and kidney problems simultaneously;
 if the level of potassium in your blood is low;
 if you are taking:
ergotamine, dihidroergotamin (medicines used to treat migraine);
 cisapride (a medicine for stomach);
 pimozide (antipsychotic);
 astemizole (allergy medicines);
 lovastatin, simvastatin (drugs to lower cholesterol).
Take special care with Lekoklar
Tell your doctor before taking this medicine:
 if you have impaired liver or kidney function;
 if you are allergic to clindamycin or lincomycin (antibiotics);
 if you use any antibacterial ear drops, such as gentamicin and neomycin;
 If you suffer from myasthenia gravis, a rare disease which causes muscle weakness;
 if you have diabetes;
 if you have or have had heart problems;
 If potassium and magnesium levels in the blood were low before treatment.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Some other medicines may influence the effects of Lekoklar, and vice versa.
These include:
Lekoklar may increase the effects of the following medicines:
 astemizole, terfenadine (antiallergic drug), pimozide (antipsychotic), cisapride (a medicine for stomach), ergotamine, dihydroergotamine (for migraine drug), lovastatin, simvastatin (drugs to lower cholesterol) (see "Do not take Lekoklar");
 alprazolam, triazolam, midazolam (sedatives);
 digoxin, verapamil (heart medicines);
 theophylline (asthma medicine);
 warfarin (an anticlotting medication);
 atorvastatin, rosuvastatin (means lower cholesterol);
 cyclosporine, sirolimus, tacrolimus (medicines that suppress the immune system);
 carbamazepine, phenytoin, valproate (medicines used to treat epilepsy)
 cilostazol (used to improve circulation in the legs);
 Colchicine (for gout);
 insulin and other medicines for diabetes (such as nateglinide, repaglinide, rosiglitazone or pioglitazone);
 methylprednisolone (cortisone to treat inflammation);
 Omeprazole (stomach medicine);
 sildenafil, tadalafil, vardenafil (medicines to treat erectile dysfunction);
 tolterodine (used to treat symptoms of overactive bladder);
 vinblastine (a drug to treat cancer);
 drugs with the risk of hearing impairment, especially aminoglycosides such as gentamicin or neomycin (antibiotic group).
The effect of Lekoklar and the effect of these drugs may be enhanced when taken together:
 atazanavir, saquinavir (medicines to treat HIV);
 itraconazole (a medicine used to treat fungal infections).
If your doctor specifically recommends you take Lekoklar and any of these drugs at the same time, you may need your doctor to monitor you more closely.
The following medicines may reduce the effect of Lekoklar:
 rifampicin, rifabutin, rifapentine (antibiotics);
 efavirenz, nevirapine (medicines to treat HIV);
 phenytoin, carbamazepine, phenobarbitone (antiepileptic drugs);
 St. John's Wort.
Please note:
Ritonavir (an antiviral medicine) and fluconazole (medicine to treat fungal infections) may enhance the effect of Lekoklar.
Lekoklar can weaken the effect of zidovudine (an antiviral drug). To avoid this, you should leave an interval of 4 hours between intake of these medicines.
Using Lekoklar while digoxin, quinidine, disopyramide or verapamil (heart medications), or other macrolide antibiotics can cause cardiac arrhythmia.
Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine.
If you are pregnant or nursing, do not take Lekoklar before checking with your doctor.
Driving and operating machinery
Overall, Lekoklar no effect on the ability to drive or operate machinery, but can cause side effects such as dizziness, confusion or disorientation. If you feel any effect, you should not drive, operate machinery and perform activities that you can expose yourself to yourself or others.
Important information about some of the ingredients of Lekoklar
This medicine contains 2.4 g sucrose per 5 ml ready to use suspension. This should be considered in patients with diabetes mellitus.
If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking this medicine.

 How to take Lekoklar

Always take this medicine exactly as your doctor tells you. If you're not sure, ask your doctor.
From prescription you can learn how much of this medicine and how often you should take. Please read it carefully. Dose your doctor prescribes will depend on the type of infection and its degree of severity. The dosage also depends on your kidney function. Your doctor will explain it.
Adults and adolescents:
The usual dose is 10 ml twice daily.
In severe infections or stomach ulcers caused by Helicobacter pylori, the usual dose is 20 ml twice daily.
Children aged between 6 months and 12 years:
The daily dose is determined by the weight of the child.
The following table provides information on usual doses:
Body weight 8-11 kg, age 1-2 years; Dose (in ml), applied two times a day: 2.5;
Body weight 12-19 kg, age 2-4 years; Dose (in ml), applied two times a day: 5;
Body weight 20-29 kg, age 4-8 years; Dose (in ml), applied two times a day: 7.5;
Body weight 30-40 kg, age 8-12 years; Dose (in ml), applied two times a day: 10;
For children weighing less than 8 kg should be given a dose of 0.3 ml / kg twice daily.
Duration of treatment
Your doctor will tell you how long you should take Lekoklar, usually between 5 and 14 days. Do not stop treatment by his own decision, for example because you or your child feel better. If you stop taking the medication early, the infection can be restored.
Usually this medicine is applied twice a day - once in the morning and once at night. You can take it with or without food.
After taking this medicine in your mouth may leave a bitter taste. This can be avoided by eat or drink something immediately after suspension.
How to measure the dose
To the drug was administered by syringe 5 ml, with a readability of 2.5, 3.75 and 5 ml. To remedy an adapter that plugs into the bottle. To measure the dose of medicine:
 Shake the bottle;
 Place the adapter in the bottle opening;
 Place the tip of the syringe into the adapter;
 Turn the bottle back;
 Pull the plunger to measure the right dose;
 Turn the bottle upright, remove the syringe, leave the adapter in the bottle and stopper.
Always shake the bottle before you measure a dose.
Drug administration with a syringe:
 The child must be stable standing upright;
 Gently place the tip of the syringe into the mouth of a child. Aim the tip of the syringe to the cheek;
 Slowly press the plunger down. Do not spray quickly;
 Allow the child to swallow medicine.
Another option is to empty the measured dose eyedropper a spoon from the child taking the medicine.
How to prepare drug
Doctor or pharmacist will prepare the medicine. To open the bottle of medicine should press down the cap, a child, and rotate it.
If we can prepare the medicine, fill the bottle with cold water, just below the measuring line marked on the bottle. Immediately afterwards, shake the bottle well. Then pour a little more water than the measuring line marked on the bottle and shake again.
You should prepare the suspension only once, at the beginning of the course of treatment.
If you take an overdose of this medicine
If you take an overdose of this medicine, contact your doctor or hospital as soon as possible.
Signs of overdose may be abdominal symptoms.
If you forget to take this medicine
If you forget to take this medicine, continue treatment following the usual dose recommended by your doctor. Do not take a double dose to make up for a missed dose.
If you stop taking this medicine
It is important to take your medicine as directed by your doctor. Do not suddenly stop taking this medicine without first discussing it with your doctor. Otherwise, the symptoms may reappear.
If you have any further questions on the use of this product, ask your doctor or pharmacist.

 Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Serious side effects
If any of the following happen, stop taking this medication and tell your doctor immediately or go to the casualty department at your nearest hospital:
Uncommon serious side effects (affects 1 to 10 users in 1,000):
 allergic reactions such as sudden difficulty in breathing, speaking or swallowing, swelling of the lips, face and throat, severe dizziness or collapse, skin rash with blisters and itching;
 yellowing of the skin or eyes, unusual tiredness or fever, dark colored urine (signs of inflammation of the liver);
 risk of clotting due to its high level of platelets in the blood.
Very rare serious side effects (affects less than 1 in 10,000 users):
 diarrhea that is severe, lasts a long time or has blood in stool with stomach pain or fever. This may be a sign of a serious inflammation of the intestines. Your doctor may discontinue treatment. Do not take medicines that slow the movement of the intestines;
 severe pain in the abdomen and back, due to inflammation of the pancreas;
 increased or decreased urine output, drowsiness and nausea caused by renal inflammation;
 serious or itchy rash, especially if it is accompanied by blistering and inflammation in the eyes, mouth, or genitals;
 unusual bruising or bleeding due to low levels of platelets in the blood;
 fast or irregular heartbeat.
Serious side effects not known:
 fever, sore throat, frequent infections caused by a serious shortage of white blood cells;
 rash, fever, changes in blood parameters (which may be a hypersensitivity syndrome (also called DRESS).
These are all serious side effects. You may need urgent medical attention.
Other possible side effects:
Tell your doctor if any of these side effects bother you:
Common (affects 1 to 10 users in 100):
 thrush in the mouth, sore mouth and tongue, staining of teeth and tongue;
 changes in sensations of smell and taste (eg, metallic or bitter taste);
 abdominal pain, nausea or vomiting, diarrhea, indigestion;
 variations in the results of studies of the kidneys;
 sleep problems;
 variations in the results of studies of the liver;
 increased sweating.
Uncommon (affects 1 to 10 users in 1,000):
 low level of white blood cells;
 liver disorders, elevation of liver enzymes in the blood;
 joint and muscle pain;
 fungal infection (candidiasis);
infections, such as vaginal;
absence or decrease of appetite, restlessness, nervousness, screaming;
dizziness, shakiness, a feeling of dizziness;
hearing problems, ringing in the ears (tinnitus);
 awareness of heart beating;
 inflammation of the lining of the stomach, constipation, flatulence, dry mouth, belching;
 itching, hives, red bumpy rash;
 muscle spasms;
 fever, weakness.
Very rare (affects less than 1 in 10,000 users):
 nightmares, confusion, disorientation, seeing, feeling or hearing things, loss of contact with reality, a sense of loss of identity;
 dizziness, convulsions, numbness and tingling of the skin;
 hard of hearing;
 liver failure;
 renal failure;
 low blood sugar, especially after the use of antidiabetic drugs and insulin at the same time.
Not known:
 certain bacterial infections of the skin and underlying tissues;
 impaired sense of smell, loss of sense of smell and taste;
 pain or weakness;
 unusual color of urine.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

 How to store Lekoklar

Keep out of reach of children.
Lekoklar Do not use after the expiry date stated on the carton after 'EXP'. Expiry date refers to the last day of that month.
Do not store above 25 ° C.
After reconstitution: Store below 25 ° C.
The suspension should be used within 14 days after preparation.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

 Additional Information

What Lekoklar
The active substance is clarithromycin.
The other ingredients are poloxamer 188, povidone K 30, hypromellose, macrogol 6000, titanium dioxide (E171), methacrylic acid - ethyl acrylate copolymer (1:1), triethyl citrate, glycerol monostearate, polysorbate 80, sucrose, maltodextrin, potassium sorbate, colloidal anhydrous silica, xanthan gum, fruit flavor (natural and artificial flavors, including maltodextrin, modified starch and maltol).
Lekoklar looks like and contents of pack
60 ml 120 ml and 240 ml white or beige pellets in bottle HDPE, with stopper, a child with PP screw and a measuring syringe PE / PP for oral (5 ml) with graduations 2,5 ml, 3,75 ml and 5,0 ml.
€ 23.00
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