Kreon caps. 40000 E 50 caps

Kreon caps. 40000 E 50 caps
€ 49.00
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Kreon contains a mixture of enzymes, called "pancreatin".
Pancreatin helps digest food. Enzymes are from pancreas of pigs.
Kreon contains small pellet which slowly release pancreatin in the intestine (enteric coated pellets, called microspheres).



Kreon caps. 40000 E 50 caps
 
KreoN WHAT IS AND WHAT IT IS USED
Kreon contains a mixture of enzymes, called "pancreatin".
Pancreatin helps digest food. Enzymes are from pancreas of pigs.
Kreon contains small pellet which slowly release pancreatin in the intestine (enteric coated pellets, called microspheres).

What applies Creon?
Creon is used in children and adults "ekzikrinna pancreatic insufficiency." This is a condition in which the body does not produce enough enzyme for digestion of food. Often found in people who have:
 Cystic fibrosis - a rare inherited disease;
 Plugged ducts of the pancreas or bile (Pankretic duct or common bile duct);
 Acute inflammation of the pancreas (pancreatitis). Can take Creon when restart taking food;
 Chronic vazoalenie pancreas;
 Pancreatic cancer;
 Partial or complete surgical removal of the pancreas (partial or total pancreatectomy);
 Partial or complete surgical removal of the stomach (partial or total gastrectomy)
 Gastrointestinal bypass;
 Syndrome Shvahman-Dayamond very rare genetic disease.
 
How does Creon?
Creon enzymes act as digest food while it passes through the intestines. You should take Creon during or after a meal. This will allow the enzyme to be mixed.

2. BEFORE YOU TAKE Creole
Do not take Creon:
 If you are allergic (hypersensitive) to the active substance (s) or any of the other ingredients of Creon.
 
If you are not sure, ask your doctor!

Take special care with Creon
In cystic fibrosis patients to high doses of pancreatin reported rare condition called "fibrosing colonopathy" in which the bowel is narrowed. However, if you have cystic fibrosis, taking more than 10,000 lipase units / kg per day and have unusual abdominal symptoms or changes in these symptoms, tell your doctor!

Additional information about pancreatic enzymes
Pancreatic glands that produce Creon and other pancreatic enzymes are from pigs fed. These animals can carry viruses. The production of Creon making several steps to reduce the risk of spreading viruses, incl. Burst and testing for specific viruses. The risk of infections caused by these or other unknown or new viruses can not be excluded completely. However, no cases have been reported in which the infection has occurred in patients.

Pregnancy and lactation
Please before taking this medicine, tell your doctor if you are pregnant or plan to become pregnant! Your doctor will decide whether you can take Creon and in what dose. Creon may be taken during breastfeeding.

Taking other medicines
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

Driving and using machines
Creon is not likely to affect the ability to drive and use machines.

3. HOW TO TAKE Creole
Always take Creon exactly as your doctor tells you. If you are not sure about anything ask your doctor or pharmacist.

How much to take
 Your dose is measured in "units lipase." Lipase is one of the enzymes pancreatin. Different dosages Creon contain different amounts of lipase;
 Always follow your doctor what dose to take Creon;
 Your doctor will adjust your dose to your needs. This depends on: your illness;
 Your weight;
 Your diet;
 How much fat is in your stools.

 If you still have oily stools, other stomach or intestinal problems (gastrointestinal symptoms), tell your doctor as your dose may need to be adjusted.
 
CF
 The usual starting dose for children under 4 years 1,000 lipase units per kilogram per meal;
 The usual starting dose for children aged 4 years, adolescents and adults is 500 lipase units per kilogram per meal.
 
Other problems with the pancreas
 The usual dose of feeding is between 25 000 and 80 000 lipase units;
 The usual dose for a snack between meals is half the dose of the main meal.
 
When to take Creon
Always take Creon during or after a meal or snack. This will allow the enzymes to be thoroughly mixed with the food, and to grind it to pass through the intestine.

How to take Creon
Swallow the capsules whole.
Do not crush or chew the capsules.
If it is difficult to swallow capsules, open them carefully and add pellets to the small amount of acidic soft food or mix them with acidic liquids. Acidic foods such as can be applesauce or yogurt. Eg acidic liquids are apple, orange or pineapple juice.
Mixing with non-acidic foods and liquids, breaking or chewing the pellets may cause irritation in your mouth or change Creon in your body.
Swallow the mixture immediately without chewing or breaking and drink some water or juice.
Do not hold Creon capsules or their contents into the mouth.
Do not store the mixture.
As a general rule, drink large amounts of fluids every day.

How long to take Creon
Take Creon unless your doctor tells you to stop. Many patients require Creon throughout his life.

If you take more Creon than you should
If you take Creon more than they should, drink plenty of water and tell your doctor.
Very high doses of pancreatin sometimes leading to increased uric acid in the urine (hyperuricosuria) and in the blood (hyperuricemia).

If you forget to take Creon
If you forget to take your dose, take the next one at the usual time the next meal. Do not try to make up the missed dose.

If you stop taking Kreon
Do not stop taking Creon without talking to your doctor.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. POSSIBLE SIDE EFFECTS
Like all medicines, Creon may cause side effects, although not everybody gets them.
 
The following side effects may occur with this medicine:
Very common (affects more than 1 user in 10):
 pain in the stomach (abdomen).
 
Common (affects less than 1 in 10 patients):
 nausea;
 vomiting;
 constipation;
 bloating;
 diarrhea.
 
These reactions can be caused by conditions that are taking Creon. In the studies, the number of patients receiving Creon having abdominal pain and diarrhea is similar to or less than patients who were not taking Creon.
 
Uncommon (affects less than 1 in 100 patients):
 rash.
 
Not known (frequency can not be estimated from the available data):
 severe pruritus (itching) and urticaria (hives);
 other serious allergic reactions may be caused by Creon, including breathing problems and swelling of the lips;
 Stricture (narrowing) of the ileo-cecum and colon (fibrosing colonopathy) have been reported in patients with cystic fibrosis taking high doses of pancreatin.
 
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist!

5. HOW TO STORE Creole
Store below 30 ° C in tightly closed containers. After opening store above 25 ° C and use within 6 months.
Keep container tightly closed to keep moisture!
Keep out of reach of children.
Creon not use after the expiry date stated on the carton. The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. ADDITIONAL INFORMATION.
What does Creon
Each capsule of Creon 40000 Ph. Eur. U contains 400 mg of pancreatin (pankreassn powder), corresponding to:
 amylase 25000 Ph. Eur. U;
lipase 40000 Ph. Eur. U;
protease 1600 Ph. Eur. U.
 
The other ingredients are:
macrogol 4000;
 hypromellose phthalate;
 dimethicone 1000;
 cetyl alcohol;
 triethyl citrate;
 zhelatinzhelezen oxide (E 172);
 titanium dioxide (E 171);
 sodium lauryl sulfate;
 gelatin.
 
Kreon looks like and contents of the pack
Kreon 40000 Ph. Eur. U is a two-colored hard gelatin capsule with the brown opaque cap and a transparent body.
Kreon gastro-resistant capsules 45000 Ph. Eur. U no 20 and 50 in bottles of high density polyethylene (HDPE) with a flip-Roll polypropylene (PP) cap.

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