Kreon 25000 E. 20 capsules

Abbott
Kreon 25000 E. 20 capsules
€ 23.00
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WHAT Kreon AND WHAT IT IS USED
Kreon contains a mixture of enzymes called "pancreatin".
Pancreatin helps digest food. Enzymes are pancreatic glands of pigs.
Kreon contains small pellet which slowly release the pancreatin in the intestines (enteric coated pellets, called microspheres).

What applies Kreon ?
Kreon is used in children and adults with "pancreatic exocrine insufficiency." This is a condition in which the body does not produce enough enzymes for digestion of food. It is often found in people who have:
Cystic fibrosis - a rare hereditary disease;
Plugged ducts of the pancreas or bile (pancreatic duct or common bile duct);
Acute inflammation of the pancreas (pancreatitis). Can take Creon when restart taking food;
Chronic inflammation of the pancreas (pancreatitis);
Pancreatic cancer;
Partial or complete surgical removal of the pancreas (partial or total pancreatectomy);
Partial or complete surgical removal of the stomach (partial or total gastrectomy);
Gastrointestinal bypass;
Syndrome Shvahman-Dayamond very rare genetic disorder.
How does Creon?
Creon enzymes act as digest food as it passes through the intestines. You should take Creon during or after a meal. This will allow the enzyme to be mixed.

2. BEFORE YOU TAKE Kreon
Do not take Kreon
If you are allergic (hypersensitive) to the active substance (s) or any of the other ingredients of Kreon
If you are not sure, ask your doctor!
Take special care with Kreon
In cystic fibrosis patients high doses of pancreatin reported a rare condition called 'fibrosing colonopathy "in which the bowel is narrowed. However, it is unknown to what happened during the trials in patients receivingKreon . However, if you have cystic fibrosis, taking more than 10,000 lipase units / kg per day and have unusual abdominal symptoms or changes in these symptoms, tell your doctor!

Additional information about pancreatic enzymes
Pancreatic glands, which produce Kreon and other pancreatic enzymes from pigs used for food. These animals can carry viruses. In the production of Creon making several steps to reduce the risk of spreading viruses, incl. demolition and testing for specific viruses. The risk of infections caused by these or other unknown or new viruses can not be excluded completely. However, there are no reported cases where infection has occurred in patients.

Fertility, pregnancy and lactation
Please, before you take the medicine, tell your doctor if you are pregnant or intend to become pregnant! Your doctor will decide whether you can take Creon and in what dose.
Creon can be taken during breastfeeding.

Taking other medicines
Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription:

Driving and using machines
Creon is not likely to affect the ability to drive and use machines.

3. HOW TO TAKE Kreon
Always take Kreon exactly as prescribed by your doctor. If you are unsure ask your doctor or pharmacist.

How much to take
Your dose is measured in "lipase units". The lipase is one of the enzymes pancreatin. Different dosages Creon contain different amounts of lipase.
Always follow your doctor what dose to take Creon.
Your doctor will adjust your dose to your needs. This depends on:
Your disease;
Your weight;
Your diet;
How much fat is in your stools.
If you still have oily stools, or other stomach or intestinal problems (gastrointestinal symptoms), tell your doctor, as you would your dose should be adjusted.
CF
The usual starting dose for children under 4 years is 1,000 lipase units per kilogram of diet.
The usual starting dose for children 4 years and over, adolescents and adults is 500 lipase units per kilogram of diet.
Other problems with the pancreas
The usual dose of a meal is between 25 000 and 80 000 lipase units.
The usual dose for a snack between meals is half the dose of main meal.
When to take Creon
Always take Creon during or after a meal or snack. This will allow the enzymes to mix thoroughly with the food to digest and it passes through the intestines.

How to take Kreon
Swallow the capsules whole.
Do not crush or chew the capsules.
If it is difficult to swallow capsules, open them carefully and add the pellets to a small amount of soft acidic food or mix them with acidic liquids. Acidic food as can be apple sauce or yogurt. Eg acidic liquids are apple, orange or pineapple juice.
Swallow mixture immediately without chewing or breaking and drink some water or juice.
Mixing with non-acidic foods and liquids, breaking or chewing the pellets can cause irritation in your mouth or change Creon in your body.
Do not hold Creon capsules or their contents into the mouth.
Do not store the mixture.
As a general rule, drink plenty of fluids every day.

How long to take Kreon
Take Kreon unless your doctor tells you to stop. Many patients need Creon throughout his life.

If you take Kreon more than you need
If you take Kreon more than you need, drink plenty of water and tell your doctor.
Very high doses of pancreatin sometimes led to increased uric acid in the urine (hyperuricosuria) and in the blood (hyperuricemia).

If you forget to take Kreon
If you forget to take your dose, take the next one at the usual time the next meal. Do not try to make up the missed dose.

If you stop taking Kreon
Do not stop taking Kreon without talking to your doctor.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. POSSIBLE SIDE EFFECTS
Like all medicines,Kreon can cause side effects, although not everybody gets them. The following side effects may occur with this medicine:
Very common (affects more than 1 in 10 patients):
pain in the stomach (abdomen).
Common (affects less than 1 in 10 patients):
nausea;
vomiting;
constipation;
bloating;
diarrhea.
These reactions may be caused by conditions which are considered Creon. In studies, the number of patients receiving Creon having abdominal pain and diarrhea similar to or less than the patients who did not take Creon.

Uncommon (affects less than 1 in 100 patients):
rash.
Not known (frequency can not be estimated from the available data):
severe pruritus (itching) and urticaria (hives);
other serious allergic reactions may be caused by Creon, including breathing problems and swelling of the lips;
Stricture (narrowing) of the ileo-cecum and colon (fibrosing colonopathy) have been reported in patients with cystic fibrosis taking high doses of pancreatin.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist!

5. HOW TO STORE Kreon
Do not store above 30 ° C.
Once opened, store below 25 ° C and use within 6 months.
Keep the bottle tightly closed in order to protect from moisture.
Keep out of the reach and sight of children.
Kreon Do not use after the expiry date stated on the carton. The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. FURTHER INFORMATION
What Kreon
Each capsule Creon 25,000 Ph.Eur.U contains 300 mg of pancreatitis (pancreatic powder) corresponding to:
amylase 18000 Ph. Eur. Units;
Lipase 25,000 Ph. Eur. Units;
protease 1000 Ph. Eur. Units.
The other ingredients are:
macrogol 4000;
hypromellose phthalate;
dimethicone 1000;
cetyl alcohol;
triethyl citrate;
gelatin;
iron oxide (E172);
titanium dioxide (E171);
sodium lauryl sulfate.
Creon looks like and contents of the pack
Creon 25,000 Ph.Eur.U is two colored hard gelatin capsule with orange opaque cap and transparent body.
€ 23.00
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