Klaricid table. 250 mg. 10 tablets

Abbott
Klaricid table. 250 mg. 10 tablets
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Klaricid 250 mg film-coated tablets is an antibiotic belonging to the group of so-called macrolide antibiotics. Antibiotics are drugs that inhibit or stop the growth of certain microorganisms (bacteria) that cause the occurrence of various infections.



Klaricid table. 250 mg. 10 tablets
 

WHAT Klaricid 250 mg film-coated tablets WHAT IT IS USED

Klaricid 250 mg film-coated tablets is an antibiotic belonging to the group of so-called macrolide antibiotics. Antibiotics are drugs that inhibit or stop the growth of certain microorganisms (bacteria) that cause the occurrence of various infections.
 
Klaricid 250 mg film-coated tablets are indicated for the treatment of infections caused by susceptible microorganisms.
 
It includes:
 Infections of the lower respiratory tract infections such as bronchitis and pneumonia;
 Infections of the upper respiratory tract such as sinusitis and pharyngitis (infection of the paranasal sinuses and throat);
 Infections of the skin and soft tissues such as folliculitis, cellulitis and erysipelas;
 In combination with potiskashi stomach acidity means clarithromycin is indicated for eradication (removal of bacteria called Helicobacter Pylori in patients with duodenal ulcer;
 Disseminated or localized infections caused by mycobacteria (Mycobacterium avium and Mycobacterium intracellulare); localized infections caused by mycobacteria (Mycobacterium chelonae, Mycobacterium fortuitum, Mycobacterium kansasii);
 Clarithromycin is used to prevent spread of the infection caused by Mycobacterium avium complex in AIDS patients with lymphocytes (white blood cells) equal to or lower than 100/mmZ;
 
As with other antibiotics before prescribing Klaricid 250 mg film-coated tablets, your doctor will take into account the frequency of resistance (resistance of microorganisms to antibiotics given) and related recommendations for prescribing antibiotics.
 

 BEFORE YOU TAKE Klaricid 250 MC COATED TABLETS

 
You should not take this medicine if:
 
 If you are allergic to the active ingredient (clarithromycin) to any of the excipients (see section 6 - Further Information) or other antibiotic of the macrolide group.
Taking the following medications: cisapride, pimozide, terfenadine and ergotamine or dihydroergotamine (please see. Writings and below)
 Have low levels of potassium in the body (hypokalemia).
 
Take special care with Klaricid 250 mg film-coated tablets
 
Your doctor may decide that this product is not suitable for you if you have certain liver dysfunction or kidney. It may be necessary to conduct further research, which will be advised by your doctor.
 
Tell your doctor if you are taking medicines containing colchicine because of possible toxic effects when co-administered with clarithromycin (the active ingredient in Klaricid), especially if you are elderly and / or suffer from renal failure.
Use of nearly all antibacterial agents, including Klaricid can lead to imbalance present in the colon bacteria and overgrowth of certain causing inflammation of the colon bacteria. This condition is known as pseudomembranous colitis and usually occurs with the onset of diarrhea during or after discontinuation of the antibiotic.
Therefore, it is important to tell your doctor about diarrhea, even a long time (1-2 months) after cessation of antibiotic treatment.
As with other antibiotics, prolonged treatment with clarithromycin may lead to the development of multiple resistant
(Insensitive to an antibiotic) bacteria and fungi. Upon the occurrence of such infections is necessary to start by your doctor treatment.
Possible exacerbation of disease symptoms myasthenia gravis (neuromuscular disorder most commonly characterized by muscle weakness) during treatment with this medicine.
 
Taking other medicines
 
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. This medicinal product may alter the effects of many drugs as other drugs can alter the effects of Klaricid.
 
It is particularly important to tell your doctor if you are taking any of the following:
 
 Cisapride (for stomach problems), pimozide (for mental disorders), terfenadine (for hay fever or allergies), ergotamine or dihydroergotamine (for migraine) - the use of these drugs is strictly prohibited Klaricid (see above)
 Digoxin (cardiovascular medicine)
Warfarin and other anticoagulants (drugs to thin the blood)
Carbamazepine or phenytoin (for epilepsy)
 Astemizole (for allergies and hay fever)
 Theophylline (for ease of breathing)
 Triazolam, alprazolam and midazolam (sedatives)
 Quinidine and disopyramide (cardiovascular medicine)
 Lovastatin or simvastatin (high cholesterol)
 Cimetidine (for stomach problems)
 Cyclosporine and tacrolimus (to suppress the immune response, most often in organ transplantation)
 Fluconazole, itraconazole (for fungal infections)
 Sildenafil, tadalafil and vardenafil (with impaired erection or erectile dysfunction etc.)
  Zidovudine, ritonavir. saquinavir, atazanavir (medicine for the treatment of HIV / AIDS)
Rifabutin (used to treat some infections)
 Eletriptan (for migraine medication)
 Ziprasidone (medicine for schizophrenia).
 
Pregnancy and lactation
 
Ask your doctor or pharmacist before taking any medicine.
Your doctor will consider the possibility of applying this product if pregnant or breastfeeding, and will discuss the benefits and risks associated with its use (including possible risks to the fetus).
 
Driving and operating machinery
 
No data on the impact of the product on the ability to drive. When driving or operating machinery it must be borne in mind the possibility of dizziness.
 

 HOW TO USE Klaricid 250 mg COATED TABLETS

 
Always take Klaricid 250 mg film-coated tablets exactly as your doctor has told you. If you are unsure ask your doctor or pharmacist.
 
The usual dose is:
 
Respiratory tract infections and infections of skin and soft tissue:
 
Adults: The usual adult dose is one 250 mg tablet twice daily. In severe infections, the dose may be increased to 500 mg twice daily. The dose should be taken at the same time each day.
The usual duration of treatment is 5 to 14 days, except in cases of community-acquired pneumonia and sinusitis that require 6 to 14 days treatment.
 
Children over 12 years: as in adults.
 
Children under 12 years: it is necessary to use oral suspension Klaricid children.
Dosage in patients with mycobacterial infections: The recommended initial dose is 500 mg twice daily. If there was no clinical or bacteriological response for 3 to 4 weeks, the dose can be increased to 1000 mg twice daily. Treatment of disseminated MAC infection in AIDS patients should be continued until then until clinical manifestations
microbiological improvement.
 
Treatment of non-consumptive other mycobacterial infections should be continued at the discretion of the treating physician.
 
Dosage for prophylaxis of MAC:
 
Adults: The recommended dose is 500 mg clarithromycin twice daily.
Eradication of Helicobacter Pylori in patients with duodenal ulcer (adults).
 
Triple therapy
Clarithromycin 500 mg twice daily in combination with lansoprazole 30 mg twice daily and amoxicillin 1000 mg twice daily for 10 days.
Clarithromycin 500 mg twice daily in combination with omeprazole 20 mg twice daily and amoxicillin 1000 mg twice daily for 7 to 10 days.
 
Dual Therapy
Clarithromycin 500 mg three times daily in combination with omeprazole 40 mg daily for 14 days followed by omeprazole 20 or 40 mg daily for another 14 days.
Clarithromycin 500 mg three times daily in combination with lansoprazole 60 mg daily for 14 days. For complete healing of the ulcer may require additional (further) suppression of gastric acidity.
 
Patients with renal impairment: in patients with renal insufficiency (creatinine clearance <30 mL / min), the dose should be reduced by half (250 mg once daily or 250 mg twice daily, in case of severe infections). In these patients, treatment should not exceed 14 days.
 
Taking 250 mg Klaricid not depend on nutrition.
 
If you take more than the dose Klaricid 250 mg film-coated tablets
 
If you take an overdose, contact your doctor immediately or go to the nearest facility for care.
 
If you miss a dose Klaricid 250 mg film-coated tablets
 
Take the missed dose as soon as you remember and then go to the normal mode of treatment. If it is almost time for your next dose, skip the missed. Do not take a double dose to make up.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
 

 POSSIBLE SIDE EFFECTS

 
Like all medicines, this medicine can cause side effects, although not everybody gets them. The most commonly reported side effects are violations of the gastrointestinal tract (nausea, vomiting, diarrhea, indigestion, abdominal pain).
 
Below are the other side effects that occurred during clinical trials and post-marketing. Do not worry about the long list of side effects when you can not have any of them.
 Infections: Fungal infections of the mouth and vagina, skin infections, gastrointestinal tract, nose and vagina
 Abnormal blood count: anemia and changes in the number of individual cells (usually decrease in white blood cells and platelets (platelet involved in blood clotting));
 Violations of the Food and metabolism: loss or increase of appetite, decrease in calcium and blood sugar, and increased uric acid chlorides;
 Psychiatric disorders: depression, insomnia, nervousness, somnolence, abnormal dreams, anxiety, confusion, disorientation, hallucinations;
 Nervous system disorders: (Loss) of taste and smell, dizziness, headache, involuntary muscle twitching;
 Eye disorders: Ear and labyrinth disorders: inflammation of the lining of the eye (conjunctivitis), hearing impairment (including deafness), and vision, dizziness;
 Cardiovascular disorders: expanding the vessels, abnormal heart rhythm, including changes in the electrocardiogram;
 Disorders of the Respiratory System: asthma, impaired breathing and impaired lung function;
 Gastrointestinal disorders: abdominal swelling, inflammation of the colon (pseudomembranous colitis see. Written above), constipation, dry mouth, belching, bleeding, inflammation of the mouth, discoloration of the tongue and teeth:
 Hepatobiliary disorders: liver inflammation (hepatitis) and jaundice (yellow skin and whites of the eyes):
 Skin and subcutaneous tissue disorders: dry skin. eczema, increased sweating, pruritus, rash, urticaria:
 Musculo-skeletal system: back pain;
 Renal and urinary disorders: inflammation of the kidneys, the presence of albumin, blood or pus in the urine;
 Immune System: various allergic reactions, some severe;• General: fatigue, edema, chest pain, malaise, pain, thirst;
 Research: There may be deviations from the normal values in the conduct of a number of laboratory tests (eg, bilirubin, serum creatinine, urea, certain liver enzymes, etc..)
 
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
 

 HOW TO STORE Klaricid 250 mg COATED TABLETS

 
Keep out of reach of children
This medicine should be stored at temperatures above 30 ° C.
Klaricid should not be used after the expiry date stated on the pack. The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
 

 ADDITIONAL INFORMATION

 
What Klaricid 250 mg film-coated tablets
 
The active substance is clarithromycin. Each tablet contains 250 mg of clarithromycin.
 
The other ingredients are: croscarmellose sodium, pregelatinized starch, microcrystalline cellulose, silica gel, povidone, stearic acid, magnesium stearate, talc, hypromellose, hydroxypropyl cellulose, propylene glycol, sorbitan monooleate, titanium dioxide, sorbic acid, vanilla, quinoline yellow (E104).
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