Klaricid SR. 500 mg. 5 tablets

Abbott
Klaricid SR. 500 mg. 5 tablets
€ 19.00
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Klaricid SR is an antibiotic belonging to the group of so-called macrolide antibiotics. Antibiotics are drugs that inhibit or stop the growth of certain microorganisms (bacteria) that cause the occurrence of various infections.



Klaricid SR. 500 mg. 5 tablets
 

Klaricid SR WHAT IS AND WHAT IT IS USED

Klaricid SR is an antibiotic belonging to the group of so-called macrolide antibiotics. Antibiotics are drugs that inhibit or stop the growth of certain microorganisms (bacteria) that cause the occurrence of various infections.
 
Klaricid SR 500 mg modified-release tablets is indicated for the treatment of infections caused by susceptible microorganisms.
 
It includes:
 Infections of the lower respiratory tract, such as bronchitis and pneumonia.
  Infections of the upper respiratory tract, such as sinusitis and pharyngitis.
  Infections of the skin and soft tissues, folliculitis, cellulitis and erysipelas.
 
As with other antibiotics before prescribing Klaricid SR, your doctor will take into account the frequency of resistance (resistance of microorganisms to antibiotics given) and related recommendations for prescribing antibiotics.
 

 BEFORE YOU TAKE Klaricid SR

 
You should not take this medicine if:
  are allergic to the active ingredient (clarithromycin) to any of the excipients (see section 6 - Further Information) or other antibiotic of the macrolide group.
  taking any of the following medications: astemizole, cisapride, pimozide, terfenadine, ergotamine, dihydroergotamine, lovastatin or simvastatin (please see. Writings and below).
 
As the dose of 500 mg daily can be reduced Klaricid SR is contraindicated in patients with severe renal insufficiency.
 
Take special care with Klaricid SR
 
Clarithromycin may be administered to a pregnant woman only if careful assessment of benefit and risk, especially during the first three months of pregnancy.
 
Use of nearly all antibacterial agents, including Klaricid can lead to imbalance present in the colon bacteria and overgrowth of certain causing inflammation of the colon bacteria. This condition is known as pseudomembranous colitis and usually occurs with the onset of diarrhea during or after discontinuation of the antibiotic. Therefore, it is important to tell your doctor about diarrhea, even a long time (1-2 months) after cessation of antibiotic treatment.
 
Possible exacerbation of disease symptoms myasthenia gravis (neuromuscular disorder most commonly characterized by muscle weakness) during treatment with this medicine.
 
Your doctor may decide that this product is not suitable for you if you have certain liver dysfunction or kidney. It may be necessary to perform additional studies, which will be advised by your doctor.
Tell your doctor if you are taking medicines containing colchicine because of possible toxic effects when co-administered with clarithromycin (the active ingredient in Klaricid), especially if you are elderly and / or suffer from renal failure.
Tell your doctor if you are taking medications to reduce blood sugar (oral or insulin). Concomitant administration of clarithromycin with these drugs can cause a drop in blood sugar, which requires it to be monitored frequently.
 
Tell your doctor if you are taking means for inhibiting the formation of blood clots in the blood (anticoagulants). Concomitant administration of clarithromycin with these drugs may increase the risk of bleeding.
 
As with other antibiotics, prolonged treatment with clarithromycin may lead to the development of multiple resistant (insensitive to an antibiotic) bacteria and fungi. Upon the occurrence of such infections is necessary to start by your doctor treatment.
Each tablet contains 115 mg lactose. You should not take this product if you know you have neponisimost to some sugars.
 
Taking other medicines
 
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
This medicinal product may alter the effects of many drugs as other drugs can alter the effects of Klaricid.
 
It is particularly important to tell your doctor if you are taking any of the following:
 
 cisapride (for stomach problems), pimozide (for mental disorders), terfenadine (for hay fever or allergies), ergotamine or dihydroergotamine (for migraine) - the use of these drugs is strictly prohibited Klaricid (see above)
 digoxin (cardiovascular medicine)
 warfarin and other anticoagulants (drugs to thin the blood)
 carbamazepine or phenytoin (for epilepsy)
 astemizole (for allergies and hay fever)
 theophylline (to ease breathing)
 triazolam, alprazolam and midazolam (sedatives)
 disopyramide (cardiovascular medicine)
 lovastatin or simvastatin (high cholesterol)
 cimetidine (for stomach problems)
 cyclosporine and tacrolimus (to suppress the immune response, most often in organ transplantation)
fluconazole, itraconazole (for fungal infections)
 sildenafil, tadalafil and vardenafil (with impaired erection or erectile dysfunction etc.)
 zidovudine, ritonavir, saquinavir, atazanavir (medicines to treat HIV / AIDS)
 rifabutin (used to treat certain infections).
 
Pregnancy and lactation
 
Ask your doctor or pharmacist before taking any medicine.
Your doctor will consider the possibility of applying this product if pregnant or breastfeeding, and will discuss the benefits and risks associated with its use (including possible risks to the fetus).
 
Driving and operating machinery
 
No data on the impact of the product on the ability to drive. When driving or operating machinery it must be borne in mind the possibility of dizziness.
 
3. HOW TO USE Klaricid SR?
 
Always take Klaricid SR, exactly as your doctor has told you. If you are unsure ask your doctor or pharmacist.
 
The usual dose is:
 
The usual recommended dose of clarithromycin modified-release tablets in adults is 500 mg once daily with food. In severe infections, the dose should be increased to 1000 mg once daily (2 x 500 mg).
 
The usual duration of treatment is 5 to 14 days, except pneumonia acquired pneumonia and sinusitis requiring treatment from 6 to 14 days. Tablets should not be crushed or chewed.
  Children over 12 years: as in adults.
  Children under 12 years: it is necessary to use oral suspension Klaricid children.
  Elderly
 
In the absence of severe renal failure dose as adults.
  Renal impairment
 
The minimum dose for patients with severe renal impairment is 500 mg. There is no need for dose adjustment in patients with moderate renal impairment (creatinine clearance 30 to 60 mL / min).
 
In patients with significantly impaired renal function should not be used because a reduction in dose. These patients can be applied Klaricid immediate-release tablets.
  Hepatic Impairment
 
Based on studies of the immediate-release clarithromycin, no dosage adjustment is required for patients with moderate and severe hepatic impairment and normal renal function.
 
If you take more than the amount of SR Klaricid
 
If you take an overdose, contact your doctor immediately or go to the nearest facility for care.
 
If you miss a dose Klaricid SR
 
Take the missed dose as soon as you remember and then go to the normal mode of treatment. If it is almost time for your next dose, skip the missed. Do not take a double dose to make up.
 
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
 

 POSSIBLE SIDE EFFECTS

 
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The most commonly reported side effects are violations of the gastrointestinal tract (nausea, vomiting, diarrhea, indigestion, abdominal pain).
 
Below are the other adverse reactions observed in clinical trials and post-marketing. Do not worry about the long list of side effects when you can not have any of them.
 
Infections: Fungal infections of the mouth and vagina, skin infections, gastrointestinal tract, nose and vagina.
 
Disorders of the blood: anemia and changes in the number of individual cells (usually decrease in white blood cells and platelets (platelet involved in blood clotting).
 
Violations by food and metabolism: reduction of blood glucose (blood sugar).
 
Psychiatric disorders: depression, insomnia, nervousness, somnolence, abnormal dreams, anxiety, confusion, disorientation, hallucinations
 
Nervous system disorders: (Loss) of taste and smell, dizziness, headache, involuntary muscle twitching.
 
Disorders of the eye, ear and labyrinth disorders: inflammation of the lining of the eye (conjunctivitis), hearing impairment (including deafness), and vision, dizziness
 
Cardiovascular disorders: expanding the vessels, abnormal heart rhythm, including changes in the electrocardiogram
 
Disorders of the Respiratory System: asthma, impaired breathing and impaired lung function
 
Gastrointestinal disorders: abdominal swelling, inflammation of the colon (pseudomembranous colitis see. Written above), constipation, dry mouth, belching, bleeding, inflammation of the mouth, discoloration of the tongue and teeth
 
Hepatobiliary disorders: liver inflammation (hepatitis) and jaundice (yellow skin and whites of the eyes)
 
Skin and subcutaneous tissue disorders: dry skin, eczema, increased sweating, pruritus, rash, urticaria
 
Disorders of bone and muscle: muscle pain, destruction of certain types of muscle tissue.
 
Renal and urinary disorders: inflammation of the kidneys, the presence of albumin, blood or pus in the urine
 
Immune system disorders: different allergic reactions, some severe
 
General disorders: fatigue, edema, chest pain, malaise, pain
 
Investigations may be a deviation from normal in the course of a number of laboratory tests (eg, bilirubin, serum creatinine, urea, certain liver enzymes, etc.).
 
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
 

 HOW TO STORE Klaricid SR

 
 Keep out of reach of children
  Klaricid should not be used after the expiry date stated on the pack. The expiry date refers to the last day of that month.
 Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
 

 ADDITIONAL INFORMATION

 
What Klaricid SR
 
 The active substance is clarithromycin. Each modified-release tablet contains 500 mg of clarithromycin.
  The other ingredients are: anhydrous citric acid (E 333), sodium alginate (E401), sodium calcium alginate, lactose monohydrate, povidone K 30, talc, stearic acid, magnesium stearate, hypromellose, macrogol, titanium dioxide (E171), sorbic acid and quinoline yellow aluminum lake (E104).
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