Ketonal. 50 mg. 25 capsules
Ketonal. 50 mg. 25 capsules
What is the active ingredient ?
The active substance is ketoprofen . Each capsule contains 50 mg of ketoprofen .
What else contain Ketonal?
Capsule contents : lactose monohydrate, magnesium stearate, colloidal anhydrous silitsiy.Kapsula : gelatine , titanium dioxide, coloring (blue V).
Formulation and packaging :
Vials containing 25 capsules ; boxes.
Ketoprofen belongs to the group of NSAIDs. Ketonal ® relieves pain and has anti-inflammatory and antipyretic ( temperaturolonizhavasht ) effect.
What is it used Ketonal?
It is used to relieve pain in adults and children over 15 years :
Lasting course of symptomatic treatment of :
- Inflammatory forms of chronic rheumatism , including rheumatoid arthritis , ankylosing spondylitis ( or related conditions , such as Syndrome Faysinger - Leroy - Reiter and psoriatic rheumatism ) ;
- Some painful and debilitating osteoarthritis .
Short-term symptomatic treatment of acute attacks of :
- Extra- forms of arthritis such as skapulohumoralni ( shoulder ) periarthritis , tendinitis , bursitis ;
- Microcrystalline arthritis ;
- Osteoarthritis ;
- Lumbago ;
- Radikulitni pain ;
- Acute posttraumatic benign diseases of the musculoskeletal system .
When not to apply Ketonal?
• If you are hypersensitive to ketoprofen or any of the excipients in Ketonal salicylates and other NSAIDs
• If you have active gastric or duodenal ulcers
• If you had a stomach or duodenal ulcer, or bleeding from the gastrointestinal tract
• If you had chronic dyspepsia ( discomfort and pain in the upper part of the stomach)
• If you suffer from severe liver and kidney disease, "If you have a tendency to bleed
• If you suffer from asthma or rhinitis
• If you are pregnant or breast-feeding
• If you are below the age of 15 years
When should observe special precautions for the use of Ketonal ®?
• If you have had gastrointestinal problems
• If you have a bleeding disorder
• If you are taking medicines for blood clotting (anticoagulants )
• If impaired hepatic or renal function
• If you have high blood pressure (hypertension ) and heart failure with edema
• If you have an infectious disease
• If you consume large amounts of alcohol or are a smoker
• If you are elderly
Tell your doctor if any of these conditions apply to you .
If you are surgery should stop taking Ketonal.
In women of childbearing potential application of this product may cause reversible inhibition of fertility.
What foods and drinks can influence the effect of Ketonal ®?
It is advisable to avoid alcohol during treatment with Ketonal.
What special precautions should be taken during pregnancy and lactation ?
Ask your doctor or pharmacist before taking any lekarstvo.Ne take Ketonal ® during the third trimester of pregnancy as nonsteroidal anti-inflammatory drugs can delay the progress of labor , premature closure of the Strait of Botallo and pulmonary hypertension in the newborn . During the first and second trimester Ketonal should be used only if the expected benefit outweighs the potential risk.
Do not take if you are breastfeeding ketone .
What you must consider when driving or operating machinery ?
For certain susceptible individuals in the non-steroidal anti-inflammatory drugs may cause dizziness , vertigo , and drowsiness . If you experience these effects, do not drive or operate machinery during treatment .
What other drugs affect the effect of Ketonal ® or can be affected by it ?
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines , even without a prescription.
Not take Ketonal ® in conjunction with other non-steroidal anti-inflammatory or salicylates , e. acetylsalicylic acid.
Effects of drugs to treat high blood pressure and diuretics may be reduced by concomitant use with Ketonal.
Effects of drugs against epilepsy and diabetes may be increased by concomitant use with Ketonal.
The risk of kidney narushteniyae greater in patients taking diuretics and ACE inhibitors concomitantly with Ketonal.
The risk of bleeding increases with concomitant use of Ketonal ® and anticoagulants ( blood clotting drugs ) or corticosteroids. Adverse effects of drugs such as cardiac glycosides , lithium, cyclosporine or methotrexate are enhanced by concomitant use of Ketonal ®, due to reduced removal.
The effect of mifepristone can be reduced during concomitant use with NSAIDs . Therefore , they should not be taken 8-12 days after the use of mifepristone.
Dose , route and duration of administration :
Always take Ketonal ® as prescribed by your doctor. Do not change the self- determination and not stop treatment without consulting a doctor .
The usual dose is one capsule Ketonal 50 mg in the morning , afternoon and evening . The recommended dose for the treatment of rheumatoid arthritis and osteoarthritis is one capsule every 6 hours .
If you take Ketonal in mild to moderate pain or menstrual pain , the recommended dose is one capsule each . 6 to 8 hours .
The maximum daily dose of ketoprofen should not exceed 300 mg.
When and how you can take Ketonal?
Take the capsule at least 100 ml of water or milk with meals . You can take antacids (drugs inhibiting gastric secretion ) at the same time to reduce the likelihood of side effects of ketoprofen on the digestive tract. Do not crush or chew the capsule.
How long can you take Ketonal?
Your doctor will tell you how long treatment. If you feel that the effect of the drug is too strong or too weak , talk to your doctor or pharmacist.
What should I do if Ketonal was adopted in very large quantities ( intentional or unintentional overdose ) ?
If you take more than the prescribed dose Ketonal ®, talk to your doctor or farmatsevt.Visoki doses of the drug can cause nausea , vomiting, epigastric pain, vomiting of blood, black stools, impaired consciousness , respiratory depression , convulsions, reduced kidney function and kidney failure.
What should you do if you forget to take Ketonal?
Take the dose as soon as you remember. If it is time for your next dose , wait and take your next dose at the appointed time. Do not take a double dose to compensate for the missed dose.
What side effects can cause the application of Ketonal?
As with any drug Ketonal can cause side effects .
The most common one that occurs in 11% of patients have a poor or painful digestion (dyspepsia ) , which occurs in an early feeling of satiation , bloating, belching after feeding , nausea , flatulence , abdominal pain and heartburn upper stomach.
Common side effects (occurring in 3-9 % of patients) were nausea , diarrhea , constipation, flatulence or abdominal pain , and weakness , light-headedness or dizziness.
1-3% of patients ( often ) can occur refusal of food (anorexia ) , vomiting, or inflammation of the lining of the mouth, tinnitus, depression or nervousness , nightmares, drowsiness , visual disturbances, skin rash or swelling ( at 2 % of the patients) .
With less than 1% of patients ( uncommon) may occur changes in the blood count , anemia , pinpoint bleeding , destruction of red blood cells ( hemolysis ) , psychiatric disorders with visual and auditory hallucinations, disorientation and speech ( delirium ) , high blood pressure , heart failure, bloody sputum ( haemoptysis ) , difficulty breathing ( dyspnea ), inflammation of the throat or nose , narrowing of the airways , swelling of the throat ( symptom of anaphylactic reaction) , hair loss, eczema , sweating, urticaria , skin reactions including peeling ( exfoliative dermatitis ) or bleeding outside the menstrual cycle in women. It is possible to display and headache.
Individual cases of colitis , intestinal perforation (including complications of polyps and diverticula ) , deterioration of the bowel disease ( ulcerative colitis and Crohn's disease) , diseases of the intestine with little bleeding and loss of protein with the characteristics of an ulcer, obstruction or perforation , liver disease with jaundice , one case of severe skin disease, kidney failure and inflammation were reported . It is possible to induce an attack of asthma .
What measures should be taken in relation to the side effects ?
Stop taking Ketonal immediately and tell your doctor or visit the nearest emergency department if you notice the following reactions :
- Swelling of hands, feet, ankles , face, lips , mouth or throat, causing difficulty in swallowing or breathing
- Rash , urticaria
- Jaundice ( yellow skin and eyes)
These are very serious but rare side effects . If you notice any of them means that you are very serious allergic reaction to Ketonal ® and need urgent medical attention.
Tell your doctor immediately if you notice any of the following :
- Black stools
- Pain in the upper stomach after meal
- Vomiting blood
- Asthma attack
These reactions are severe, but rare, require immediate medical attention.
If you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
Storage Instructions :
Keep out of reach of children .
Store below 25 ° C in the original package .
Do not use after the expiry date stated on the packaging.