KAVINTON amp. 10 mg. 2 ml. 10 amp
KAVINTON amp. 10 mg. 2 ml. 10 amp
WHAT KAVINTON INFUSION AND WHAT IT IS USED
Kavinton infusion is a medicament for treating the symptoms of some diseases associated with disorders of cerebral circulation . Kavinton infusion solution is also used to reduce neurological or psychological symptoms associated with the disorders of cerebral circulation , for the treatment of certain ophthalmic diseases and otologichni result of vascular disorders , or for reduction of symptoms associated therewith.
2 . BEFORE YOU USE KAVINTON
What you should know before using this medicine ?
In case of increased intracranial pressure , cardiac arrhythmias or long QT QT- interval is allowed to take Kavinton infusion only after complete individual medical decision.
In Kavinton iifuzionen solution can be detected a small amount of sorbitol (160 mg / 2 ml), which may slightly influence the daily diet of diabetic patients . Therefore, if you have diabetes , ask your doctor for advice.
Tell your doctor if you have fructose intolerance ( intolerance to fruit sugar) or an enzyme deficiency ( fructose- 1 ,6- difosfataza ), since in these cases the drug administration should be avoided .
When not to be used Kavinton infusion ?
It must not be used in case of hypersensitivity vinpocetine or any of the other ingredients of the product ;
During pregnancy and lactation ;
In case of acute severe hemorrhagic stroke and ischemic heart disease , severe cardiac arrhythmias ;
Its use in children is contraindicated ( due to lack of data from relevant clinical trials) .
It allowed the use of Kavinton infusion during pregnancy and lactation ?
Kavinton infusion solution should be administered during pregnancy .
Vinpocetine , the active ingredient of Kavinton infusion is excreted in human milk , so Kavinton should not be used during breastfeeding.
Have an impact Kavinton infusion on ability to drive and use machines?
During treatment with Kavinton you are allowed to drive unless your doctor recommends otherwise . No evidence of any effect of vinpocetine on ability to drive and use machines.
Can you take other medicines during treatment with Kavinton ?
Other medicines may influence the effect of Kavinton why you should inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Take special care with Kavinton infusion in case of concomitant use of heparin. Injection is chemically incompatible with heparin, therefore , they can be mixed in one syringe , but it is possible concurrent anticoagulant therapy .
You should tell your doctor if you are taking a medicine containing alpha- methyl- dopa, drugs affecting the central nervous system , or anticoagulants antiarrhythmics (medicines to prevent the formation of blood clots) .
3 . HOW TO USE KAVINTON INFUSION
How will be given Kavinton infusion ?
Kavinton infusion will be diluted and will then be injected slowly into a vein by intravenous infusion. Infusion means you will be given a pint of liquid and will last about an hour, hour and a half. The injection should not be given for undiluted (ie you be injected directly to the contents of the ampoule ) or as an intramuscular injection. The initial dose is typically 20 mg ( 2 vials) . This dose can be increased to 1 mg / kg body weight daily for 2-3 days , depending on the tolerance of the patient. The median duration of treatment was 10-14 days , the usual daily dose is 50 mg / day (5 ampoules in 500 ml infusion ) relative to the body weight of 70 kg. There is no need for dose adjustment in patients with renal and hepatic disease.
Administration of 1 mg / kg body weight can be considered safe . Accidental overdose can occur cardiac side effects . In this case Kavinton treatment should be stopped and you will be closely monitored for signs of heart disorders , will be given appropriate symptomatic and supportive care. Also will be carefully monitored your vital signs (heart rate , blood pressure). There is no known antidote to Kavinton infusion. Please tell your doctor if you suspect an overdose .
4 . POSSIBLE SIDE EFFECTS
Like all medicines . Kavinton infusion may cause side effects, although not everybody gets them.
Blood and lymphatic system disorders:
rare: thrombocytopenia, agglutination of red blood cells;
very rare: anemia.
Immune system disorders :
very rare: hypersensitivity.
Metabolism and nutrition disorders:
rare: hypercholesterolemia , diabetes mellitus ;
very rare: anorexia.
uncommon elated ;
Rare : agitation , anxiety ;
very rare: depression.
Nervous system disorders :
Rare : headache , dizziness, hemiparesis , and somnolence ;
very rare: tremor , loss of consciousness , hypotension, syncope .
Eye disorders :
rare: hyphema , hyperopia , blurred vision, myopia ;
very rare: conjunctival hyperemia , edema of the papilla , diplopia.
Ear and labyrinth disorders:
rare: impaired hearing , hyperacusis , hypoacusis , vertigo ;
very rare: tinnitus .
rare: Myocardial ischemia / infarction, angina pectoris , bradycardia , tachycardia, extrasystoles , palpitations ;
very rare: cardiac failure, atrial fibrillation .
rare: hypotension, hypertension, flushing ;
very rare: changes in blood pressure, venous insufficiency .
rare: abdominal discomfort , dry mouth , nausea ;
very rare: salivation , vomiting .
Skin and subcutaneous tissue disorders:
rare: erythema , hyperhidrosis , urticaria ;
very rare: dermatitis , pruritus.
General disorders and administration site conditions:
Uncommon: feeling hot ;
Rare : asthenia , chest discomfort , phlebitis / thrombosis at the site of injection.
Uncommon: low blood pressure;
rare: increase in blood pressure, ECG : an extension of the QT-interval , depression of ST-segment elevated blood urea ;
very rare: increase in serum LDH, extending the ECG PR, abnormal electrocardiogram .
If any of the side effects gets serious, or you notice other effects not listed in this leaflet , please tell your doctor or pharmacist.
5 . STORAGE KAVINTON INFUSION
Store below 25 ° C in the original package to protect from light.
Keep out of reach of children.
Do not use after the expiry date stated on the pack .
6 . ADDITIONAL INFORMATION
The active substance is vinpocetine ( 10 mg of vinpocetine in each ampoule ) .
Excipients include ascorbic acid , sodium metabisulphite , tartaric acid , sorbitol , benzyl alcohol , water for injections.
Looks like Kavinton infusion and contents of the pack
The infusion solution is colorless to pale greenish colored solution . Folding carton contains 10 ampoules of 2 ml in a plastic tray .