INVIRASE 500 mg. 120 capsules

ROCHE
INVIRASE 500 mg. 120 capsules
€ 349.00
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PHARMACOTHERAPEUTIC GROUP
INVIRASE is an antiviral product. It belongs to a class of medicines called protease inhibitors. It is intended for the treatment of an infection caused by the human immunodeficiency virus

Indications for treatment
Invirage is used to treat people with HIV infection over 16 years of age. It is used in combination with ritonavir and other antiretroviral medicinal products.


BEFORE YOU START INVIRASE TREATMENT
Do not take INVIRASE:
- if you are hypersensitive to saquinar, ritonavir or any of the other ingredients of the product.
- if you suffer from severe liver disease
- if you are taking any of the medicines listed below
Medicines not to be taken concomitantly with Invirase are:
- terfenadine and astemizole
- pimozide
- cisapride
- ergo-alkaloids
- midazolam, triazolam
- amiodarone
- flecainide and propafenone
- rifampicin
simvastatin and lovastatin


HOW TO ACCEPT INVIRASE?
Always take Invirase exactly as prescribed by your doctor. You should ask your doctor if you are not sure. Invirase is available as 200 mg capsules. Your doctor will prescribe Invirase in combination with Norvir and other medicines to treat HIV. The dose of Invirase is five capsules of 200 mg and one Norvir capsule of 100 mg twice a day.
Invirase should be taken at the same time as Norvir up to 2 hours after a meal. Capsules should be taken without chewing, with water.
If you feel that the effect of Invirase is too strong or too weak, tell your doctor.


POSSIBLE SIDE EFFECTS
The most commonly observed side effects of saquinavir, taken with ritonavir, are gastrointestinal tract, most commonly nausea, diarrhea, fatigue, vomiting, gas and abdominal pain.
Other less commonly reported side effects that may occur include: rash, pruritus, headache, peripheral neuropathy, weakness, vertigo, depression, anxiety, difficulty falling asleep, libido, warts, mouth ulcers, abdominal discomfort, indigestion, fever, pain, constipation, loss of appetite, and chest pain.

Rare side effects are inflammation of the liver and convulsions
Very rare side effects are allergic reactions, drowsiness and renal dysfunction.
Your doctor will check your blood regularly to detect possible disorders such as reduced red blood cell counts, reduced white blood cell counts that fight infection, decreased platelet count, elevated liver enzymes, impaired kidney function, blood sugar changes , increased fat in the blood and labels for the function of other organs.
Cases of diabetes mellitus or increased blood sugar have been reported in patients receiving such treatment or other protease inhibitors.
In patients with type A or B hemophilia, an increased risk of bleeding has been reported with treatment with this or another protease inhibitor. If this happens to you, contact your doctor immediately.
Combination antiretroviral therapy may cause changes in body shape due to changes in fat distribution. these changes may include loss of fat from the legs, arms and face, increased fat in the abdomen and other internal organs, chest enlargement and fat deposits in the neck area. The cause of this condition and its late effects on health are not yet known. Combination antiretroviral therapy may also cause elevated lactic acid and sugar in the blood, hyperlipidemia and insulin resistance.
There have been reports of muscle pain, increased sensitivity or weakness, especially in combination antiretroviral therapy, including protease inhibitors with nucleoside analogues. In rare cases these muscular disorders were serious.
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