Furosemide amp.10 mg. Ml. 2 ml. 10 amp
Furosemide amp.10 mg. / Ml. 2 ml. 10 amp
Furosemide WHAT IS AND WHAT IT IS USED FOR ?
Furosemide Sopharma product group of diuretics ( drugs that increase urine output, drainage and eliminate water retention in the body) . Used to treat swelling from heart , lung , liver and kidney origin, hypertensive crisis (in addition to other therapeutic measures) .
Sopharma Furosemide injection is applied where necessary to achieve the rapid onset emergencies or when it is difficult or impossible adoption in tablets .
2 . BEFORE YOU USE furosemide
Do not use Furosemide
- If you are allergic (hypersensitive ) to the active substance or to any of the ingredients of a medicinal product;
- If you are allergic ( hypersensitive) to sulfonamides ;
- In cases of dehydration (dehydration ) or hypovolemia ( low blood volume ) ;
- Renal failure or anuria ( formed little or no urine ) ;
- Renal failure due to poisoning toxic to the kidneys or liver substances;
- Renal failure associated with hepatic coma ( severe liver disease ) ;
- On a greatly reduced amount of potassium and sodium in the blood ;
- If the patient is comatose or prekomatozno due to severe hepatic impairment ;
- If you are breastfeeding .
Take special care with Furosemide
- If you have hypotension ( low blood pressure) ;
- If you have an enlarged prostate or difficulty urinating ;
- If you suffer from diabetes or gout ;
- If you have hepatorenal syndrome (severe liver damage with subsequent prolonged deterioration of renal function);
- If you know that you have a reduced amount of protein in the blood ;
- In preterm newborns ;
- If you suffer from porphyria (an inherited disease of the liver, which does not produce enough hemoglobin) ;
- When administered with risperidone (to treat mental illness) .
- There should be regular monitoring of serum levels of sodium , potassium, calcium , chlorine , magnesium, creatinine.
Using other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Tell your doctor if you are taking medicines to treat high blood pressure, including other diuretics ( metolazone ) antinevralgichni and hypnotic drugs ( carbamazepine, fenobarbitap ) , antiepileptic drugs ( phenytoin) , antidepressants ( reboxetine ), anti-inflammatory and antirheumatic products ( indomethacin , aspirin ), corticosteroid , agents that suppress the immune system ( methotrexate tsiklosiorin ) for the treatment of gout , diabetes , heart failure ( digoxin ) , asthma ( theophylline ), antibiotics ( such as cephalosporins or aminoglycosides ), lithium products , cisplatin , carbenoxolone and sucralfate ( for the treatment of peptic ulcer disease ) ; korgikotropin ; medicaments for the treatment of fungal infections ( amphotericin B); laxatives ; likvoris ( in a greater amount in the treatment of cough ), products for the treatment of elevated levels of cholesterol in the blood ( cholestyramine ) .
In some patients, after administration of contrast agents in radiological increased risk of worsening of renal function.
Furosemide Sofarma can reduce the therapeutic effect of adrenaline and noradrenaline .
Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine. pregnancy
Furosemide crosses the placenta. Should not be used during pregnancy unless in exceptional testimony and if the benefit outweighs the risk to the fetus , requiring continuous monitoring of the fetus. breastfeeding
Furosemide passes into breast milk and may suppress milk secretion . If appointed treatment with furosemide , breastfeeding should be discontinued.
Driving and using machines
Avoid driving or operate any tools or machines as furosemide may cause a reduction in blood pressure and dizziness , decreased attention and the ability to drive and use machines.
Important information about some of the ingredients of Furosemide
This product contains sodium, less than 1 mmol ( 23 mg) per dose , i.e. essentially sodium .
3 . HOW TO USE furosemide ?
Always use Sopharma Furosemide exactly as your doctor tells you . If you are not sure, ask your doctor or pharmacist.
The medicinal product is administered usually intravenously and in rare cases muscle . After the injection treatment may be switched to treatment with furosemide tablets .
The dosage and duration of treatment is determined by the attending physician .
If you use more than the amount of Furosemide
Overdose with this medicine may appear irregular heartbeat , loss of fluids to manifestations of severe hypotension (low blood pressure) and shock, acute renal failure, clogging of the vessels (thrombosis ) , delirious states , apathy and confusion.
Treatment of these symptoms is carried out by a doctor in a medical facility .
If you forget to use Furosemide
Do not take a double dose to make up for a missed dose.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4 . POSSIBLE SIDE EFFECTS
Like all medicines, Sopharma Furosemide can cause side effects, although not everybody gets them .
Adverse drug reactions are presented by system organ :
Blood and lymphatic system disorders:
Anemia , low platelet count ( leading to an increased risk of bleeding or bruising ), low white blood cells ( which may lead to an increased risk of infection ) ; hemoconcentration (reduced plasma volume with a relative increase of the blood cells ) . There may be a suppression of the bone marrow , leading to the development of infections or bleeding . Immune system disorders
Severe anaphylactic / anaphylactoid reactions ( swollen face or tongue , shortness of breath or difficulty breathing , pale, cold , clammy skin , rapid heart rate ), in very rare cases to shock.
Metabolism disorders and nutrition
Dehydration and disturbances in the amount of salts in the blood - increased thirst, feeling dizzy or light-headed , fainting, confusion , headache, low blood pressure , muscle pain, cramps or spasms, muscle weakness, heart rhythm disorders , and gastrointestinal disorders. Severe dehydration may lead to clot formation or attack of gout .
Reversible increase in creatinine and urea , cholesterol and triglycerides in the blood.
Harder controlling glucose levels in the blood.
Nervous System Disorders
Feeling tingling in arms and legs.
In patients who already have liver problems may develop more serious liver disease known as hepatic encephalopathy. Occurs with forgetfulness, seizures , mood changes, and coma.
Ear and labyrinth
Tinnitus , hearing impairment . This affects predominantly patients who have a renal disease, as well as more rapid intravenous administration of furosemide .
Reduced blood pressure, orthostatic collapse (lowering of blood pressure with a change in position of the body ) .
Inflammation of blood vessels (vasculitis) , a tendency to form blood clots in the vessels .
Nausea, vomiting , diarrhea, pancreatitis ( severe pain in the abdomen or back, as manifestations of inflammatory disease of the pancreas ) .
Elevations of liver enzymes , itching , yellowing of the skin or eyes, dark urine (signs of liver disease ) .
Skin and subcutaneous tissue disorders
Itching, hives, other rashes, erythema multiforme, bullous pemphigoid , Stevens -Johnson syndrome (severe skin disease with redness , blistering , affecting different parts of the body including the mouth, eyes and genitals) , toxic epidermal necrolysis , exfoliative dermatitis, purpura ( pinpoint hemorrhages on the body ), increased sensitivity to light.
Renal and urinary disorders
Dysuria , which can be the manifestation of acute urinary retention. Interstitsiapen nephritis - inflammation of the kidneys.
Prematurity: nephrocalcinosis - deposition of calcium salts in the kidneys, leading to renal dysfunction ; nephrolithiasis - formation of kidney stones.
Congenital, familial and genetic disorders
Increased risk of patent ductus arteriosus ( congenital heart disease) , when administered to premature infants during the first weeks of life .
General disorders and administration site conditions
Local pain after intramuscular administration . Fever.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet , please tell your doctor or pharmacist.
5 . HOW TO STORE furosemide
In the original package to protect from light at a temperature below 25 ° C. Do not freeze !
Keep out of reach of children.
Do not use Furosemide after the expiry date stated on the carton and vial . The expiry date refers to the last day of that month. Do not use Furosemide Sopharma if you notice discoloration of the solution.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required . These measures will help to protect the environment.
6 . ADDITIONAL INFORMATION
What does Furosemide ?
The active agent is furosemide 20 mg in one vial of 2 ml. The other ingredients are sodium chloride , sodium hydroxide (I mol / l), water for injections
Furosemide looks like and contents of the pack ?
A clear solution of pale yellow color , substantially free of the particles.
2 ml solution for injection in a brown glass ampoules , marked the opening of the vial - colored dot . Opening the ampoule is done by pressing your thumb on the mark ( point ) of the neck of the ampoule .
10 ampoules in PVC foil in I or 10 blisters in a carton with leaflet.