FROMILID 250 mg. 14 tablets
FROMILID belongs to a group of macrolide antibiotics.
FROMILID is used to treat infections caused by susceptible clarithromycin
Upper respiratory tract infections (otitis media, sinus, throat, tonsils, bronchi and lungs);
Skin and subcutaneous tissue;
It is also used for the eradication of Helicobacter pylori in patients with duodenal ulcers in combination with other medicines prescribed by the doctor.
FROMILID is used in adults and children 12 years and older.
2. BEFORE YOU TAKE FROMILID
Do not take Fromilnd:
if you are allergic (hypersensitive) to clarithromycin, to any excipients of FROMILID or to other macrolide antibiotics;
if you have low potassium levels in the blood (himokaliemiya);
if you have severe liver disease and kidney problems;
if you are taking medicines for high cholesterol (eg lovastatin or simvastatin);
if you and / or someone in your family have heart problems that can lead to serious heart rhythm disturbances (syndrome of long QT);
if you are already taking any of the following medications:
ergotamine or dihydroergotamine (for migraine);
cisapride (for stomach disorders);
pimozide (for some mental illnesses);
terfenadine or astemizole (for hay fever or allergy).
Take special care with FROMILID:
Consult your doctor before you start taking FROMILID:
If you have severe kidney problems;
If you have liver disease;
If you develop severe or persistent diarrhea during or after taking FROMILID should consult your doctor immediately;
If you suffer from a disease called myasthenia gravis;
If you are already taking colchicine, as this can cause serious side effects;
Prolonged use of FROMILID may result in the overgrowth of resistant bacteria (superinfection);
If you have any heart disease;
If you have a slow heart rate (bradycardia);
In case you have low levels of magnesium in your blood;
If you suffer from porphyria you should not take clarithromycin.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
The effect of treatment can be influenced if FROMILID is taken with certain other medicines. You may need to change the dose, to take other precautions, or in some cases to stop taking one of the medicines. This particularly applies to the following medicines:
Carbamazepine, phenobarbital, phenytoin, valproate (medicines for epilepsy);
Theophylline (for asthma);
Warfarin (a blood thinner);
Ergotamine or dihydroergotamine (for migraine);
Triazolam, midazolam or alprazolam (sedatives);
Disopyramide, digoxin, quinidine or verapamil (used to treat abnormal heart rhythms);
Simvastatin or lovastatin (used to treat high cholesterol);
Pimozide (for the treatment of schizophrenia or other psychotic disorders);
Fluconazole or itraconazole (to treat fungal infections);
Rifabutin, rifampicin (antibiotics active against certain infections);
Efavirenz, nevirapine, zidovudine, ritonavir, atazanavir or saquinavir (medicines for HIV);
Cyclosporine, sirolimus or tacrolimus (after organ transplants);
Terfenadine or astemizole (for hay fever or allergy);
Cisapride or omeprazole (for stomach disorders);
Colchicine (for gout);
Tolterodine (in bladder problems);
Insulin or oral antidiabetic drugs (for diabetes);
St. John's wort (herbal medicine);
Cilostazol (to improve circulation in the legs);
Methylprednisolone (inflammatory diseases);
Sildenafil, tadalafil or vardenafil (erectile dysfunction);
Vinblastine (for cancer treatment).
Taking FROMILID with food and drink
You can take FROMILID without food. Swallow the tablets whole with at least half a cup of liquid.
Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine.
As the safety of FROMILID during pregnancy has not been established, you can take it only after an assessment of the benefit / risk ratio.
It is not recommended to breast-feed during treatment with FROMILID.
Driving and using machines
FROMILID may make you feel confused, disoriented or dizzy, cause seizures, panic or change in sense of reality, or see things that are not there. Make sure you do affects so before you drive or operate machinery.
3. HOW TO TAKE FROMILID
Always take FROMILID exactly as your doctor tells you. If you are not sure, ask your doctor or pharmacist.
Should not crush the tablets. Swallow them whole with at least half a cup of liquid.
Adults and children over the age of 12 is usually given 250 mg to 500 mg every 12 hours.
Treatment continued for 6 to 14 days.
To treat infections pa Helicobacter pylori, associated with duodenal ulcers.
There are several effective combinations of medicinal products for the treatment of Helicobacter pylori, in which FROMILID tablets are taken with one or two other drugs. Your doctor will decide which of the combinations is most appropriate for your treatment.
The dosage and duration of treatment depend on the type of infection, the site of infection, the age of the patient and response to treatment. Take your medicine as prescribed by your doctor.
If you have the impression that the effect of the drug is too strong or too weak, you should consult with your doctor or pharmacist.
If you take more than you need FROMILID
If you take an overdose you should immediately consult your doctor or pharmacist. Overdose usually causes gastrointestinal disturbances (nausea, vomiting, abdominal pain), headache and confusion. Treatment is symptomatic.
If you forget to take FROMILID
Do not take a double dose to make up the missed dose.
If you forget to take a dose at the time, take it as soon as possible. If it is almost time for your next dose, skip the missing dose and with his usual dosing schedule.
If you stop taking FROMILID
Take this medicine as long as your doctor has prescribed. If you stop treatment too early, the disease can recur.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, FROMILID can cause side effects, although not everybody gets them.
Adverse reactions are classified into the following groups depending on the frequency:
Very common: Affects more than 1 user in 10;
Common: Affects 1 to 10 users in 100;
Uncommon: Affects 1 to 10 users in 1000;
Rare: Affects 1 to 10 users in 10,000;
Very rare: Affects less than 1 user in 10,000;
Not known: frequency can not be made from the available data.
headache, altered sense of taste;
diarrhea, nausea or vomiting, indigestion (dyspepsia), stomach pain;
abnormal liver test;
rash, excessive sweating (hyperhidrosis).
infections, such as infections of the stomach and intestines, thrush, vaginal infections;
low white blood cell count, anemia, disorders of other white blood cells;
loss of appetite;
nervousness, anxiety, hysterical laughter;
dizziness, sleepiness, shaking (tremor);
tinnitus, dizziness (vertigo) and diseases of the ears;
changes in heart rhythm, awareness of the heartbeat (palpitations);
inflammation of the mouth (stomatitis), inflammation of the tongue (glossitis), inflammation of the stomach (gastritis), heavy episodic rectal pain (proctalgia);
constipation, dry mouth, belching, bloating, excess gas in the stomach and vomiting, return of stomach acid into the esophagus (GERD);
violation of the flow of bile (cholestasis), inflammation of the liver (hepatitis);
itching, hives, fever, small red spots on the skin (maculopapular rash);
muscle pain (myalgia), muscle spasms and cramps;
fever, chest pain, feeling of general discomfort (malaise);
tiredness (fatigue), weakness (asthenia), chills;
changes in the values of certain chemicals in the blood (seen in blood tests);
severe or persistent diarrhea which may have blood or mucus (pseudomembranous colitis), skin infection (erysipelas, eritrazma);
a sharp drop in the number of white blood cells which makes infections more likely (agranulocytosis);
reduction in blood platelets (thrombocytopenia);
serious allergic reaction which causes difficulty in breathing or dizziness (anaphylactic reaction);
low blood sugar (hypoglycemia);
abnormal dreams, confusion, disorientation, seeing or hearing things (hallucinations), psychotic disorder, depression;
convulsions, inability to sense of taste, changes in smell;
irregular heartbeat, rapid heartbeat;
inflammation of the pancreas, tongue and discoloration of the teeth;
yellowing of the skin and other liver disorders;
serious illness with blistering of the skin, mouth, eyes and genitals (syndrome of Stevens-Johnson), severe illness and peeling of skin (toxic epidermal necrolysis), acne, rash medicines;
abnormal muscle breakdown which can lead to kidney problems (rhabdomyolysis), pain or weakness in muscles (myopathy);
increased risk of bleeding, discoloration of urine.
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
5. HOW TO STORE FROMILID
Keep out of the reach and sight of children.
Do not store above 25 ° C. Store in the original package in order to protect from moisture.
FROMILID should not be used after the expiry date stated on the packaging. The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medications that are no longer needed. These measures will help to protect the environment.
6. FURTHER INFORMATION
The active substance is clarithromycin (clarithromycin).
Each tablet contains 250 mg or 500 mg of clarithromycin.
Other ingredients in the film coated tablets of 250 mg and 500 mg are corn starch, microcrystalline cellulose, silica, colloidal anhydrous, pregelatinized starch, polacrilin potassium, talc and magnesium stearate in the tablet core and hypromellose, talc, a colorant quinoline yellow (E104) titanium dioxide (E171) and propylene glycol (E1520) in the film coating.