FRAGMIN 7500IU. 2 ampoules
Fragmin is available as a solution for injection in pre-filled disposable syringes, ampoules or multi-dose vials.
What type of medicine is Fragmin
Fragmin belongs to a group of medicines called low molecular weight heparin or antiplatelet drugs that help prevent blood clots. Fragmin acts on substances that are found in the blood and cause coagulation. Besides Fragmin prevents the formation of clots, it can also help to break the clots that have already formed in blood vessels.
What is Fragmin?
It can be used in patients in hemodialysis or hemofiltration to prevent clotting in the pipes of the apparatus.
Fragmin is also used for the treatment of conditions known as acute deep venous thrombosis, pulmonary embolism and unstable forms of ischemic heart disease.
Deep vein thrombosis is a condition in which blood clots in the legs and in the pulmonary embolism clot entering the lungs.
In ischemic heart disease heart arteries narrow due to plaque deposition in fat stores. This reduces blood flow to the heart. In the unstable forms of ischemic heart disease one of these plates is cleaved and / or a clot is formed, thereby hindering the blood supply to the heart.
In such patients is more likely to get a heart attack if not treated with antiplatelet drugs such as Fragmin.
Fragmin is also used for the prevention of trombizata in surgery, and in patients with limited mobility due to severe medical conditions.
Fragmin is used in long term treatment of symptomatic venous thromboembolism, occurring as deep vein thrombosis or pulmonary embolism for the reduction of recurrence of VTE in patients with cancer
BEFORE YOU TAKE FRAGMIN
You should tell your doctor if:
- You have experienced an allergic reaction after previous administration of Fragmin or a similar product;
-Have a stomach ulcer or dnanadesetoprastnika;
- You have had a stroke;
- Suffering from whatever was a condition in which you may be prone to easy bleeding. This may include patients with severe liver or kidney failure or uncontrolled hypertension;
- You have endocarditis;
- Have thrombocytopenia;
- Have recently had surgery or trauma to the central nervous system, eyes and / or ears;
- You have problems with your kidneys or liver;
- You are pregnant, planning to become pregnant or breast-feeding;
- Are taking other medicines;
- You are or need to have, a epidural or spinal anesthesia or spinal puncture.
Fragmin should not be taken during pregnancy unless your doctor recommends otherwise. Women of childbearing potential should use effective contraception. Contact your doctor immediately if you become pregnant, think you are pregnant or planning to become pregnant while taking Fragmin.
While taking Fragmin is not recommended to breast-feed, since it is not known whether it is excreted in human milk.
HOW TO TAKE FRAGMIN
This medicine will be given by a doctor. Fragmin is administered subcutaneously or intravenously. It should not be administered intramuscularly.
Dose koyaot you will be given depends on your specific condition and the likelihood of clot formation.
If you are being treated for deep thrombosis or pulmonary embolism will be administered subcutaneous injection. The dose that you will be given 200 IU / kg body weight once daily or 100 IU / kg body weight twice daily.
If you are on hemodialysis or hemofiltration, the drug will be injected intravenously / vein /. In patients with chronic kidney problems and patients without risk of bleeding, where it lasts more than 4 hours, you will usually be given a starting dose of 30-40 IU / kg bodyweight. This will be followed by an infusion of 10-15 IU / kg each hour. If your procedure lasts less than four hours may be given the same dosage or you are given a single injection of 5,000 IU. In patients with acute renal failure or patients at high risk of bleeding, the usual dose is 5-10 IU / kg body weight every hour.
For thrombosis prophylaxis in surgery Fragmin is administered subcutaneously. In patients at risk for a blood clot, the usual dose is 2,500 IU two hours before surgery and 2500 IU per each following morning. This lasts typically 5 to 7 days until the patient mobilization. Other patients may have an increased risk of blood clots. In such, the usual dose is 2500 IU to two hours prior to surgery and 2500 IU 8 to 12 hours later, but no sooner than 4 hours after the operation and 5000 IU subcutaneously every next morning. Alternatively, you could apply 5,000 IU every night. This treatment also usually takes 5 to 7 days.
Orthopedic procedures Fragmin normally used to 5 weeks after surgery, and after it is applied 5,000 IU daily.
In patients with prolonged restriction on locomotor activity was 5000 IU Fragmin administered subcutaneously once a day, usually 12 to 14 days or longer.
In the treatment of unstable forms of ischemic heart disease is administered 120 IU / kg body weight subcutaneously every 12 hours. The maximum dose at 12 hours 10 000 IU. It is recommended that concomitant treatment with acetylsalicylic acid.
In long-term treatment of symptomatic venous thromboembolism reduction of recurrence of VTE in patients with cancer Fragmin apply special monthly scheme using fixed dose syringes.
Safety and effectiveness in children and adolescents has not been established and therefore, dalteparin should not be used in this age group.
POSSIBLE SIDE EFFECTS
The most common are - hemorrhage, hematoma at the injection site, reversible non-immunological mediated thrombocytopenia, pain at injection site, allergic reactions, and transient elevations of hepatic transaminases.
Particular attention is needed if you are taking Fragmin and you are spinal or epidural anesthesia. Make sure your doctor knows about your treatment.