Exelon. 1.5 mg. 28 capsules

NOVARTIS
Exelon. 1.5 mg. 28 capsules
€ 69.00
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The active substance in Exelon is rivastigmine
Rivastigmine belongs to a group of substances called cholinesterase inhibitors. Patients with Alzheimer's dementia or patients with dementia in Parkinson's disease, certain nerve cells die in the brain, which leads to the release of high levels of the neurotransmitter acetylcholinea substance that allows the nerve cells to be connected with each other

Exelon. 1.5 mg. 28 capsules

 
 
What is Exelon and what it is used?
The active substance in Exelon is rivastigmine .
Rivastigmine belongs to a group of substances called cholinesterase inhibitors. Patients with Alzheimer's dementia or patients with dementia in Parkinson's disease, certain nerve cells die in the brain , which leads to the release of high levels of the neurotransmitter acetylcholine ( a substance that allows the nerve cells to be connected with each other) . Rivastigmine works by blocking the enzymes that break down acetylcholine - acetylcholinesterase and butyrylcholinesterase . By blocking these pathways Exelon allows to achieve high levels of acetylcholine in the brain , which help to reduce the symptoms of Alzheimer's disease and dementia associated with Parkinson's disease.
Exelon is used to treat adult patients with mild to moderately severe Alzheimer's dementia, a progressive brain disorder that gradually affects memory, intellectual ability and behavior . The capsules and oral solution can also be used for the treatment of dementia in elderly patients with Parkinson's disease.
2 . What you should know before you take Exelon?
Do not take Exelon
- If you are allergic to rivastigmine (the active ingredient in Exelon) or any of the other ingredients of this medicine (listed in Section 6) .
- If you have a skin reaction spreading beyond the patch , if more intense local reaction ( such as blistering , raised skin irritation , swelling ), and if you do not improve within 48 hours after removal of the transdermal patch.
If this applies to you, tell your doctor and do not take Exelon.

Warnings and Precautions
Talk to your doctor before taking Exelon:
- If you have or have ever had an irregular heartbeat .
- If you have or have ever had an active stomach ulcer .
- If you have or have ever had difficulty in urination.
- If you have or have ever had seizures.
- If you have or have ever had asthma or severe respiratory disease .
- If you have or have ever had impaired renal function.
- If you have or have ever had abnormal liver function.
- If you have tremors.
- If you have a low body weight.
- If you have gastrointestinal disturbances such as feeling sick (nausea ) , being sick (vomiting) and diarrhea. It is possible to get dehydrated ( lose too much fluid ) if vomiting or diarrhea are prolonged .
If any of these apply to you , it may be necessary for your doctor to closely monitor your condition while you are taking this medicine.
If you have not taken Exelon for several days, do not take the next dose until you have talked to your doctor.

Use in children and adolescents
There is no relevant use of Exelon in the pediatric population in the treatment of Alzheimer's disease.

Other medicines and Exelon
Tell your doctor or pharmacist if you are taking , have recently taken or take any other medicines , including medicines obtained without a prescription.
Exelon should not be given with other drugs that have similar effects to Exelon . Exelon might interfere with anticholinergic medications ( drugs used for the relief of abdominal pain or cramping , for the treatment of Parkinson's disease, or for the prevention of motion sickness ) .
If you have to undergo surgery whilst taking Exelon, tell your doctor before you are given anesthesia because Exelon may exaggerate the effects of some muscle relaxants during anesthesia.
Pregnancy, lactation and fertility
If you are pregnant or breast-feeding, you may be pregnant or planning to become pregnant , ask your doctor or pharmacist before taking this medicine.
If you are pregnant , the benefits of using Exelon should be assessed against the possible effects on your unborn child. Exelon should not be used in pregnancy , unless absolutely necessary.
You should not breast-feed during treatment with Exelon.

Driving and using machines
Your doctor will tell you whether your illness allows safe to drive or operate machinery . Exelon may cause dizziness and somnolence, mainly at the beginning of treatment or when increasing the dose. If you feel dizzy or drowsy , do not drive, operate machinery or do other activities that require your attention .

3 . How to take Exelon?
Always take this medicine exactly as described in this leaflet or as your doctor tells you . If you are not sure, ask your doctor, pharmacist or nurse.

How to start treatment ?
Your doctor will tell you what dose to take Exelon .
• Treatment generally begins at a low dose .
• Your doctor will gradually increase the dose depending on how you respond to treatment.
• The highest dose that should be administered is 6,0 mg twice daily.
Your doctor will check whether your medicine is having the desired effect. Your doctor will also track and weight while taking this medicine.
If several days have not taken Exelon, do not take the next dose before talking to your doctor.

Taking this medicine
• Tell the person who takes care of you are taking Exelon.
• To benefit from your medicine , you should take it every day.
• Take Exelon twice a day, morning and evening meals .
• Swallow the capsules whole with a drink .
• Do not open the capsules squeeze .

If you take more than the amount of Exelon
If you take more Exelon, than you should, tell your doctor. You may need medical attention. Some people who have accidentally taken too much Exelon, have sick (nausea) , being sick (vomiting), diarrhea , high blood pressure and hallucinations . Can also occur in heart rate and seizures.
If you forget to take Exelon
If you see that you forget to take your dose of Exelon, wait and take the next dose at the usual time. Do not take a double dose to make up for a missed dose.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4 . Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them .
When you start taking your medicine or dose escalation is often possible to have side effects . The side effects will gradually disappear once the body gets used to the drug.

Very common ( may affect more than 1 in 10 people)
• Feeling dizzy
• Loss of appetite
• Stomach problems such as feeling sick (nausea ) or being sick (vomiting), diarrhea

Common ( may affect up to 1 in 10 people)
• Anxiety
• Sweating
• Headache
• Acids
• Weight loss
• Abdominal pain
• Feelings of anxiety
• Feeling tired or weak
• Malaise
• Trembling or confusion

Uncommon (may affect up to 1 in 100 people)
• Depression
• Sleep disorders
• Fainting or sudden loss of consciousness
• Changes in liver function

Rare (may affect up to 1 in 1000 people)
• Chest pain
• Rash, itching
• seizures ( convulsions)
• Ulcers in the stomach or intestines
Very rare ( may affect up to 1 in 10 000)
• High blood pressure
• Urinary tract infection
• Seeing things that are not there ( hallucinations)
• Heart rhythm problems , such as fast or slow heartbeat
• Bleeding from the gut - unfolds as blood in the stool or vomit
• Inflammation of the pancreas - the symptoms are severe pain in the upper abdomen , often combined with feeling sick (nausea ) or being sick (vomiting)
• Worsening of symptoms of Parkinson's disease or receipt of such symptoms - such as muscle rigidity , hindering the movements

Not known ( can not be estimated to assess the frequency )
• Strong feeling sick (vomiting), which can cause tearing of the tube that connects the mouth to the stomach ( esophagus )
• Dehydration ( losing a lot of fluid)
• Hepatic impairment (yellowing of the skin, yellowing of the whites of the eyes, unusually dark urine or unexplained nausea, vomiting, fatigue and loss of appetite)
• Aggression, anxiety
• Irregular heart rhythm

Patients with dementia and Parkinson's disease
In these patients, some side effects occur more frequently. They also observed some additional side effects:

Very common ( may affect more than 1 in 10 people)
• Trembling
• Fainting
• Sudden fall

Common ( may affect up to 1 in 10 people)
• Anxiety
• Anxiety
• Slow and rapid heartbeat
• Sleep disorders
• Excessive salivation and dehydration
• Abnormally slow movements or uncontrollable movements
• Worsening of symptoms of Parkinson's disease or receipt of such symptoms - such as muscle rigidity , hampering movement and muscle weakness

Uncommon (may affect up to 1 in 100 people)
• Irregular heart beat and poor control of movements

Other side effects seen with Exelon transdermal patch that can occur in solid form:

Common ( may affect up to 1 in 10 people)
• Fever
• Acute confusional
• Decreased appetite
• Urinary incontinence (inability to hold enough urine)
Uncommon (may affect up to 1 in 100 people)
• overactivity (hyperactivity , restlessness )

Not known ( can not be estimated to assess the frequency )
• Allergic reactions at the site of patch application , such as blisters or irritation of the skin
If any of these side effects, consult your doctor as it may need medical attention.
If you get any side effects, tell your doctor, pharmacist or nurse. This includes all listed in this leaflet .

5 . How to store Exelon?
• Keep out of reach of children.
• Do not use this medicine after the expiry date stated on the carton after " EXP" . The expiry date refers to the last day of that month.
• Do not store above 30 ° C.
• Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required . These measures will help to protect the environment.

6 . Package Contents and more information
Contents of Exelon?
- The active substance is rivastigmine hydrogenotartrate .
- The other ingredients are hypromellose , magnesium stearate, microcrystalline cellulose, colloidal silicon dioxide , gelatin , yellow iron oxide (E172), red iron oxide (E172), titanium dioxide (E171) and shellac .
Each Exelon 1,5 mg capsule contains 1,5 mg of rivastigmine. Each Exelon 3,0 mg capsule contains 3,0 mg of rivastigmine. Each Exelon 4,5 mg capsule contains 4,5 mg of rivastigmine. Each Exelon 6,0 mg capsule contains 6,0 mg of rivastigmine.

Exelon looks like and contents of the pack ?
- Exelon 1,5 mg hard capsules containing off-white to pale yellow powder in a yellow cap and yellow body, with red imprint "EXELON 1,5 mg" on the body.
- Exelon 3,0 mg hard capsules containing off-white to pale yellow powder in a capsule with orange cap and orange body, with red imprint "EXELON 3 mg" on the body.
- Exelon 4,5 mg hard capsules containing off-white to pale yellow powder in a red cap and red body with a white imprint "EXELON 4,5 mg" on the body.
- Exelon 6,0 mg hard capsules containing off-white to pale yellow powder in a red cap and orange body, with red imprint "EXELON 6 mg" on the body.
Packed in blister with three different pack sizes ( 28, 56 and 112 capsules) and plastic bottles of 250 capsules , but not all of them can be sold in your country.
 
 
 
 
€ 69.00
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