Enap. 10 mg. 25 mg. 90 tablets

Enap. 10 mg.  25 mg. 90 tablets
€ 19.00
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Enap H 10 mg/25 mg is used to lower blood pressure.
Enalapril belongs to the angiotensin converting enzyme (ACE). This medicine inhibits the activity of angiotensin converting enzyme

 Enap. 10 mg. / 25 mg. 90 tablets

What Enap H 10 mg/25 mg and what it is used?

Enap H 10 mg/25 mg is used to lower blood pressure.
Enalapril belongs to the angiotensin converting enzyme (ACE). This medicine inhibits the activity of angiotensin converting enzyme. During treatment with enalapril, blood vessels dilate, causing lower blood pressure and increase blood flow and oxygen to the heart muscle and other organs. Hydrochlorothiazide belongs to a group of drugs that increase the excretion of urine (diuretic). This medication increases urine flow and thus lowers blood pressure. The antihypertensive activity of enalapril and hydrochlorothiazide combination is stronger than the activity of the two drugs separately.
This medicine is indicated for treatment of high blood pressure (hypertension) when required combination therapy.

 Before you take Enap H 10 mg/25 mg

Do not take Enap H 10 mg/25 mg
 If you are allergic (hypersensitive) to enalapril, hydrochlorothiazide or sulfonamides or any other component of Enap H 10 mg/25 mg or other ACE inhibitors;
 If the use of other ACE inhibitors already cause allergic reactions with sudden swelling of lips and face, neck, hands and possibly feet or choking or hoarseness (angioedema);
 If you have hereditary angioedema or angioedema due to some other unknown causes;
 If you have severe renal or hepatic function;
 If you are unable to urinate;
 If you are pregnant for more than three months. (It is also better to avoid Enap-H 10 mg/25 mg in early pregnancy -. See. Pregnancy section).
Take special care with Enap H 10 mg/25 mg
During treatment with Enap H 10 mg/25 mg, check your blood pressure regularly. Ask your doctor about the appropriate blood pressure and when to go for the next review.
 If you have low blood pressure and impaired water-salt imbalance, you have a heart condition called "aortic stenosis", "hypertrophic cardiomyopathy" or "difficulty swollen blood";
 If you are taking medicines that increase the amount of urine (diuretics);
 If you have kidney problems or are on dialysis;
 If you have had a recent kidney transplant
 If you have liver problems;
 If you are being treated for diabetes;
 If you suffer from gout;
 If you have had an allergic reaction to lactose because lactose is one of the inactive ingredients in this medicine;
 If you are being treated for severe connective tissue disease called systemic lupus erythematosus;
 If you are on a diet and particularly a diet with low salt intake;
 If you were told by your doctor that you have intolerance to some sugars;
 If you are taking lithium, used to treat certain mental disorders.
You should also inform your doctor that you are taking enalapril / hydrochlorothiazide:
 Possible before surgery (even at the dentist), tell your doctor that Enap H 10 mg/25 mg, since there is an increased risk of hypotension during general anesthesia;
 If treatment with Enap H 10 mg/25 mg prolonged cause severe diarrhea, vomiting and profuse sweating, consult your doctor as fluid loss can lead to hypotension;
 Before treatment as dialysis or some other procedure to clean the blood (apheresis) and treat hypersensitivity to wasp or bee venom to (desensitization), tell your doctor that Enap H 10 mg/25 mg, since there is an increased risk of adverse hypersensitivity reactions.
Before carrying out tests for parathyroid function (these are glands in the neck that control the level of calcium in the blood), notify your doctor that Enap H 10 mg/25 mg.
In addition to measuring your blood pressure, your doctor may want to do blood tests to check your kidneys are working properly before you start taking Enap-H 10 mg/25 mg and repeat it at regular intervals during treatment.
You must tell your doctor if you think you are (or might become) pregnant.
Enap-H 10 mg/25 mg are not recommended in early pregnancy, and must not be taken if you are pregnant after the third month, as it may cause serious harm to your baby if used at that stage (see Pregnancy section).
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Other medicines used to treat high blood pressure;
 Potassium supplements, potassium-containing salt substitutes or potassium-sparing diuretics (eg, spironolactone, amiodarone);
 Analgesic and anti-inflammatory drugs (NSAIDs, such as ibuprofen, diclofenac);
 Medicines to treat depression (eg lithium, tricyclic antidepressants, antipsychotics);
 Drugs that increase the amount of urine (diuretics);
 Medicines for lowering cholesterol (eg, cholestyramine, colestipol resins);
 Drugs to suppress tumor growth (cytotoxic drugs such as cyclophosphamide, methotrexate);
 Drugs used to treat certain diseases such as rheumatism, arthritis, allergies, asthma and some blood disorders (corticosteroids);
 Drugs used to treat abnormal heart rhythms (procainamide, amiodarone or sotalol);
 Drugs used to treat arrhythmias (digitalis);
Active substances used in some medicines for coughs and colds (sympathomimetics) or noradrenaline and adrenaline used in low blood pressure, shock, heart failure, asthma or allergies. If used together with Enap-H 10 mg/25 mg these drugs can keep your blood pressure high.
 Antidiabetic drugs such as insulin. Enap-H 10 mg/25 mg may cause a drop in blood sugar when taken concomitantly with antidiabetic agents.
 Muscle relaxants (eg tubocurarine used in anesthesia);
 Gold by injection to treat arthritis (sodium aurotiomalat).
Taking Enap-H 10 mg/25 mg with food and fluid
You can take it during or after a meal with a drink.
Do not drink alcohol during treatment because it enhances the effects of
Enap-H 10 mg/25 mg on lowering blood pressure.
Pregnancy and lactation
Ask your doctor or pharmacist for advice before taking any medicine.
You must tell your doctor if you are pregnant or think you may be pregnant. Usually, your doctor will advise you to take another medicine instead
Enap-H 10 mg/25 mg, since Enap-H 10 mg/25 mg are not recommended during pregnancy. This is because Enap-H 10 mg/25 mg crosses the placenta and its use after the third month of pregnancy can lead to potentially dangerous effects fetus and newborn.
Tell your doctor if you are breastfeeding or plan to breastfeed. Nursing infants (during the first few weeks after birth), particularly premature infants is not recommended while taking Enap-H 10 mg/25 mg.
If the baby is older you should consult your doctor about the benefits and risks of taking Enap H 10 mg/25 mg while breastfeeding, compared with other treatments.

Driving and using machines:

Individual patients Enap-H 10 mg/25 mg may cause dizziness or weakness, especially in early treatment and thus indirectly and transiently impair the ability to drive a motor vehicle or operating machinery. Until you know how you respond to the treatment, do not drive a vehicle or operate machinery.
Important information about some of the ingredients of Enap-H 10 mg/25 mg:
Enap-H 10 mg/25 mg contains lactose. If your doctor tells you that you have an intolerance to some sugars, consult your doctor before taking this medicine.

 How to take Enap H 10 mg/25 mg

Always Enap-H 10 mg/25 mg exactly as your doctor tells you. If you are not sure you should consult your doctor or pharmacist.
The usual dose is 1 to 2 tablets one a day. You have to take tablets whole, during or after a meal with some liquid. You get used to taking medicine regularly, preferably in the morning and always at the same time.
Treatment with N-Enap 10 mg/25 mg is long-term treatment unless circumstances arise that require its suspension. Since it is necessary to take the medication regularly, take care to always have enough tablets for continued treatment.
Use in children:
Efficacy and safety of Enap-H 10 mg/25 mg in children has not been established why he should not be given to children.
If you take more than the amount Enap-H 10 mg/25 mg
The most common signs of overdose are nausea, palpitations, dizziness and fainting, due to significantly lower blood pressure (hypotension).
After taking many tablets, you may receive the following: more abundant and more frequent urination, severe hypotension irregular heartbeat, seizures, partial paralysis and unconsciousness. If the patient is conscious after taking an overdose, try to induce vomiting and immediately call a doctor.
If you forget to take Enap-H 10 mg/25 mg
If you forget to take your medicine, take it as soon as possible, unless there were only a few hours until the next scheduled dose. In that case, just take your next scheduled dose without duplicate it.
Do not take a double dose to make up.
If you stop taking Enap-H 10 mg/25 mg
You should be aware that treatment with any blood pressure lowering medicine will not cure the disease, but it will help to lower blood pressure and maintain it at the desired level. Thus the consequences and complications of hypertension will be prevented or reduced.
If you have any further questions on the use of this product, ask your doctor or pharmacist.

 Possible side effects

Like all medicines, Enap H 10 mg/25 mg can cause side effects, although not everybody gets them.
Adverse reactions are classified into the following groups in order of frequency:
Very common - affecting more than 1 in 10 users;
Common - Affects 1 to 10 users in 100;
Uncommon - affects 1 to 10 users in 1000;
Rare - Affects 1 to 10 users in 10,000;
Very rare - affecting less than 1 user in 10,000;
Not known - frequency can not be made from the available data.
Very common:
 Blurred vision;
 Irritating cough;
 Feeling sick (nausea);
 Weakness (asthenia).
 Low levels of potassium in the blood, elevated cholesterol, elevated triglycerides, elevated levels of uric acid in the blood;
 Headache, depression, loss of consciousness (syncope), taste perversion;
 Low blood pressure (hypotension) and effects related to hypotension, abnormal heart rhythm, chest pain (angina), fast heartbeat;
 Difficulty breathing (dyspnea)
 Diarrhea, abdominal pain;
 Muscle cramps;
 Chest pain, fatigue;
 Increased level of potassium in the blood serum creatinine.
 Ringing in the ears (tinnitus);
 Flushing, fast heartbeats (palpitations), heart attack and stroke, possibly due to an excessive reduction of blood pressure in high-risk patients;
 Runny nose (rhinorrhea), sore throat and hoarseness, asthma;
 Ileus, inflammation of the pancreas (pancreatitis), being sick (vomiting), indigestion (dyspepsia), constipation, poor diet (anorexia), upset stomach, dry mouth, ulcers, accumulation of intestinal gas (flatulence), impaired renal function , renal failure, protein in the urine (proteinuria);
 Itching, sweating, hair loss;
 Joint pain (arthralgia);
 Sensitization or tremors (caused by low blood sugar), low magnesium levels;
 Restlessness, fever;
 Confusion, Insomnia, insomnia, nervousness, dizziness (vertigo), tingling or numbness as a feeling in arms or legs (paresthesia), decreased libido;
 Blood urea increased, reducing the level of sodium in the blood.
 Changes in blood count (neutropenia hipohemoglobinemiya, decreasing hematocrit, thrombocytopenia, leukopenia);
 High blood sugar;
 Strange dreams, sleep problems, impaired movement (paresis);
 Enlarged lymph nodes, autoimmune diseases, poor blood flow to the fingers and toes, causing redness and pain (Raynaud's syndrome);
 Fluid in the lungs, runny nose or sore, eosinophilic pneumonia (symptoms may be cough, fever and difficulty breathing);
 Swelling or mouth ulcers, infection, pain and swelling of the tongue;
 Liver failure or hepatitis, that may cause yellowing of the skin (jaundice);
 Excessive flushing, rash with blisters and skin irritation, especially in the hands and feet, in or around the mouth accompanied by fever (syndrome Stevens-Johnson), scaling of the skin;
 Kidney problems such as back pain and reduce the amount of urine;
 Breast enlargement in men;
 Elevated liver enzymes or bilirubin in blood.
Very rare
 Intestinal angioedema. Symptoms may include abdominal pain, nausea and vomiting, elevated blood calcium.
 Increase in serum calcium.
Not known
 Hyponatremia (caused by SIADH).
There have been a complex of symptoms: fever, serozit, vasculitis, myalgia, arthralgia, increased titer of antinuclear antibodies (ANA), elevated sedimentation rate of erythrocytes, eosinophilia and leukocytosis.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

How to store Enap H 10 mg/25 mg

Keep out of reach of children.
Do not use Enap H 10 mg/25 mg after the expiry date stated on the carton.
The expiry date refers to the last day of that month.
Do not store above 25 ° C.
Store in the original package to protect from moisture.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

  Additional Information

What Enap H 10 mg/25 mg
Active ingredients: enalaprilov maleate and hydrochlorothiazide (enalapril maleate and hydrochlorothiazide).
Each tablet Enap-H 10 mg/25 mg Contains 10 mg enalaprilov maleate (enalapril maleate), which is equivalent to 7,64 mg enalapril (enalapril) and 25 mg hydrochlorothiazide (hydrochlorothiazide).
The other ingredients are: lactose monohydrate, quinoline yellow (E104), maize starch, talc, sodium hydrogen carbonate, magnesium stearate, pregelatinized starch.
€ 19.00
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