Enap HL . 10 mg. 12.5 mg
Enap HL . 10 mg. / 12.5 mg
What are tablets Enap-HL?
Tablets Enap-HL is used to lower blood pressure. Enalapril belongs to the angiotensin converting enzyme (ACE) inhibitors. This medicine inhibits the activity of angiotensin converting enzyme. During treatment with enalapril, blood vessels dilate, causing lower blood pressure and increase blood flow and oxygen to the heart muscle and other organs. Hydrochlorothiazide belongs to a group of drugs that increase the excretion of urine (diuretic). This medication increases urine flow and thus lowers blood pressure. The antihypertensive activity of enalapril and hydrochlorothiazide combination is stronger than the activity of the two drugs separately. The maximum effect of enalapril occurs after 6 to 8 hours after dosing. The effect of hydrochlorothiazide on increased urine output usually appear 2 hours after administration and most after 3 to 4 hours after dosing. The effect on blood pressure occurs after 3 to 4 days of treatment. The effect of the combination lasts up to 24 hours. The therapeutic effect is reached after several weeks of treatment.
What tablets are used Enap-HL?
This medicine is indicated for treatment of high blood pressure (hypertension) when required combination therapy.
BEFORE YOU USE Enap-HL
Tell your doctor if you have any chronic diseases, metabolism disorders, hypertension, or if you are taking other medicines.
Who should not use tablets Enap-HL?
You should not use the medicine if you svarhchuvstvitelni to enalapril, hydrochlorothiazide, and sulfonamides or to any of the excipients of the medicinal product or to other ACE inhibitors, where use of other ACE inhibitors are already causing a hypersensitivity reaction with sudden swelling of lips and face, neck, hands and possibly feet or suffocation and graying (angioedema), if you have a history of angioedema or HAE from some other unknown cause, severe renal and hepatic function, primary aldosteronism, if you have a kidney transplant during the pregnancy and lactation.
Precautions and warnings
During treatment Enats-HL check your blood pressure regularly. Refer to your doctor about the right for you blood pressure and when you go to the next checkup. Before taking Enats-HL, tell your doctor if you are being treated for diabetes, gout, asthma, diseases of the liver, kidneys, cardiovascular system (heart attack and stroke), pancreas, bone marrow, immune system or allergy. You should also tell your doctor if you have had a heart attack or stroke, electrolyte disturbances, surgery of the nervous system (simpatikotomiya) and if you are allergic to sulfonamides. Tell your doctor if you follow a diet, especially a diet low in salt. At the beginning of therapy require more frequent medical examinations. You should not miss examinations even if you feel well. Your doctor will determine the frequency control your reviews.
After taking the first dose of the drug or even a few hours after taking it may appear significant decrease in blood pressure (hypotension). It is usually manifested by nausea, palpitations, dizziness and fainting. If hypotension occurs, lie low pillow and physician. Hypotension and its effects are rare and transient. Transient hypotension not prevent the continuation of treatment with this medicine. After hypotension, you will usually tolerate subsequent doses well. In re hypotension accompanied by disease symptoms (ie, nausea, palpitations, dizziness and fainting), consult your doctor. If during treatment appeared dizziness, fainting or unconsciousness when rising from a lying or sitting position, consult your doctor. It is always recommended to get up slowly, especially if you are an adult. Possible before surgery tell your doctor that you are taking Enap-HL, because there is an increased risk of hypotension during general anesthesia. If treatment with Enap-HL leads to prolonged severe diarrhea, vomiting and profuse sweating, consult your doctor because of fluid loss can cause hypotension.
Before hemodialysis treatment as probable or certain other blood cleansing procedures (apheresis) and treat hypersensitivity to poison a wasp and bee (desensibilizaniya), tell your doctor that you are taking Enap-HL, because there is an increased risk of adverse hypersensitivity reactions. Prior to study parathyroid function, tell your doctor that you are taking Enap-HL.
Efficacy and safety of Enap-HL in children have not been studied and therefore should not be given to children.
Taking Enap-HL with food and fluid
You can take the drug during or after meals with a liquid. Do not drink alcohol during treatment because it potentiates the effect of Enap-HL on lowering blood pressure.
Ask your doctor or pharmacist for advice before taking any medicine. Enap-HL crosses the placenta and may cause fetal harm, therefore, you should not take during pregnancy, especially in the second and third trimesters. Enap-HL is not recommended for women planning to become pregnant. Women who become pregnant during treatment should consult a physician for further treatment as soon as possible, because hypertension during pregnancy is dangerous for them and the fetus.
Ask your doctor or pharmacist for advice before taking any medicine. Enap-HL is secreted in breast milk, so mothers treated with this product are advised not to breastfeed.
Effects on ability to drive and use machines
Individual patients Enap-HL can cause hypotension and dizziness, especially in early treatment and thus indirectly and transiently impair the ability to drive a motor vehicle or operating machinery. Until you know how you respond to the treatment, do not drive a vehicle or operate machinery.
What other drugs could interact with Enap-HL?
Tell your doctor or pharmacist if you are taking any other medicines (including OTC). Before you stop taking the medicine you take regularly or start taking any other medication, you should consult your doctor. This applies mainly to other drugs used to treat hypertension, heart failure, diabetes, a urine output, potassium tablets, anti joint pain, aspirin, sedatives, hypnotics, medications for the treatment of rheumatism, gout, mental disorders, gastrointestinal ulcers, lowering blood cholesterol or chronic bronchitis and / or asthma. Concomitant use of Enap-HL and certain drugs for the treatment of the aforementioned diseases can weaken the effect of these medicines or to strengthen their side effects can affect the impact of Enap-HL or increase the risk of worsening of renal function, as well can cause an allergic reaction. Do not use non-prescription medicines without consulting a doctor. This applies mainly to drugs for the treatment of colds, pain relievers, salt substitutes or potassium-containing medicines.
HOW TO USE Enap-HL?
Dosage and method of administration
Strictly follow the doctor's instructions. You should not change your dose or stop treatment without first consulting your doctor. The usual dose is 1 to 2 tablets one a day. You should take the tablets or during or after a meal with some liquid. You get used to taking medicine regularly, preferably in the morning and always at the same time. Lechenieto.s Enap-HL is a long-term treatment, unless circumstances arise that require its suspension. Since it is necessary to take the medication regularly, take care to always have enough tablets for continued treatment.
If you have the impression that the effect of the medication is too strong or too weak, talk to your doctor or pharmacist.
If you take more Enap-HL, than you should
If you have taken an overdose, lie low pillow and call the doctor. The most common signs of overdose are nausea, palpitations, dizziness and fainting, due to significantly lower blood pressure (hypotension). After taking many tablets, you may receive the following: more abundant and more frequent urination, severe hypotension irregular heartbeat, seizures, partial paralysis and unconsciousness. If the patient is conscious after taking an overdose, try to induce vomiting and immediately call a doctor.
If you forget to take Enap-HL
Do not take a double dose to replace forgotten! If you forget to take your medicine, take it as soon as possible, unless there were only a few hours until the next scheduled dose. In that case, just take your next scheduled dose, not duplicate it.
Effects when treatment with Enap-HL is stopped
You should be aware that treatment with any blood pressure lowering medicine will not cure the disease, but it will help to lower blood pressure and maintain it at the desired level. Thus the consequences and complications of hypertension will be prevented or reduced.
POSSIBLE SIDE EFFECTS
Like all medicines Enap-HL can also have side effects.
Stop taking the medication immediately and contact your doctor if you experience:
Confusion, dizziness, vertigo, fainting and unconsciousness;
Increased or irregular heartbeat or chest pain;
Decreased urine output;
is sudden fever, chill, difficulty swallowing;
Unusual tiredness and weakness o Muscle cramps, especially in the calves;
Abdominal pain, vomiting o Deterioration of gout;
Sudden swelling of lips and face, neck, and as the hands and feet, difficulty breathing, or hoarseness;
»Skin rash, severe itching of the skin, thickening, red spots all over the skin.
If you are experiencing dry, irritating cough, headache, nausea, diarrhea, increased sensitivity to sunlight, fatigue or tiredness and disturbing or disturb your quality of life, consult your doctor. If you notice any side effects, even if they are not mentioned in this leaflet, please tell your doctor or pharmacist.
Do not use after the expiry date stated on the packaging.
Keep out of reach of children. Protect from moisture. Do not store above 25 ° C. Only the prescribing information on prescription.