Enap . 5 mg. 30 tablets

Enap . 5 mg. 30 tablets
€ 19.00
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Enap medicine to lower blood pressure (antihypertensive). It belongs to the group of angiotensin converting enzyme (ACE). This drug inhibits the activity of ACE. During treatment with Enap, blood vessels dilate, which lowers blood pressure and increases the flow of oxygen to the heart muscle and other organs.



Enap . 5 mg. 30 tablets
 
Enap WHAT IS AND WHAT IT IS USED FOR ?

Enap medicine to lower blood pressure (antihypertensive ) . It belongs to the group of angiotensin converting enzyme ( ACE ) . This drug inhibits the activity of ACE . During treatment with Enap , blood vessels dilate , which lowers blood pressure and increases the flow of oxygen to the heart muscle and other organs.

This medicine is for treating hypertension, hypertension, renal diseases (including renal failure and renal dysfunction due to diabetes ) , congestive heart failure and left ventricular dysfunction ( in those patients without evidence of disease) .

2 . BEFORE YOU TAKE Enap

Do not take Enap
If you are allergic (hypersensitive) to enalapril or any of the excipients of Enap ,
If you are allergic to other ACE inhibitors
co already developed allergic reactions with sudden swelling of lips and face , neck, arms and legs eventually or suffocation or hoarseness (angioedema) after taking ACE inhibitors
If you have hereditary angioedema or angioedema due to some other unknown reasons
If you are more than 3 months. ( It is better to avoid taking tablets Enap in early pregnancy - see pregnancy section).
Take special care with Enap

During treatment with Enap , you should regularly measure your blood pressure. Ask your doctor about the appropriate level of blood pressure and when to go for the next checkup .

At the beginning of treatment and / or during the establishment of the most appropriate dose of Enap , more frequent medical examinations are required. You should not miss them , even if you feel well .
The doctor will determine the frequency of the examinations.
- If you are being treated for diabetes - If you have heart problems ;
- If you have a disease of the blood vessels in the brain ;
- If you have blood problems such as low or lack of white blood cells ( neutropenia / agranulocytosis) , low platelet count (thrombocytopenia) or a reduced number of red blood cells ( anemia) ;
- If you are taking tablets to increase the amount of urine .
- If you are on a diet , especially low in salt, take potassium supplements, potassium -sparing drugs or potassium-containing salt substitutes ;
- If you have prolonged severe diarrhea,
- If vomiting or sweating profusely
- If you have low blood pressure (if you often feel faint or dizzy , especially when getting up ) ;
- If you have liver problems if you have kidney damage , if you are on dialysis ;
- If you recently had a kidney transplant and are taking drugs to prevent rejection of the kidney ;
- If you have any other immune diseases or allergies. You should know that black people are at increased risk of these types of reactions to ACE inhibitors. If you have ever had an allergic reaction with swelling of face , lips, tongue and / or the glottis , and difficulty swallowing or breathing ; If you develop jaundice
- If a prolonged , persistent cough ; If you are taking lithium;
- If you have a collagen vascular disease (eg lupus erythematosus , rheumatoid arthritis or scleroderma ) if you treatment that suppresses the immune system, taking medication allopurinol or procainamide, or a combination of several of them: If you are over the age of 70 ;

When your doctor (or dentist ) planned surgical procedure and anesthesia , treatment by hemodialysis or other procedure to clean the blood ( apheresis ) or treatment of hypersensitivity ( desensitization ) of venom from wasps and bees , tell the doctor that you are taking enalapril .

You should tell your doctor if you think you are (or might become) pregnant. Enap tablets is not recommended in early pregnancy, and should not be
take if you are pregnant for more than three months , as it may cause serious harm to your baby if used at that stage (see pregnancy ) .

Taking other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

In particular, tell your doctor or pharmacist if you are taking any of these medicines:

- Other medicines to lower blood pressure , such as beta - blockers or water tablets ( diuretics) ;
- Potassium supplements , potassium-containing salt substitutes or potassium-sparing water tablets (eg, spironolactone , amiodarone )
- Anaesthetic and anti-inflammatory drugs ( NSAIDs, such as ibuprofen, diclofenac )
- Medicines to treat diabetes (including oral antidiabetic agents and insulin)
- Lithium (a medicine used to treat some types of depression)
- Medicines to treat depression ( tricyclic antidepressants)
- Medicines to treat mental health problems ( antipsychotics )
- Certain medicines for cough and cold medicines for weight loss ( sympathomimetic ) Aspirin ( acetylsalicylic acid)

- Drugs used to dissolve blood clots ( thrombolytics ) Alcohol

- Gold by injection for the treatment of arthritis (sodium aurotiamalat ) . Taking Enap with food and drink

You may take Enap before, during or after meals.
Not recommended the use of alcoholic beverages during treatment with Enap because alcohol enhances the action of Enap in lowering blood pressure .

Pregnancy and lactation

Ask your doctor or pharmacist before taking any medication.
pregnancy
You should tell your doctor if you think you are (or might become) pregnant. Your doctor will normally advise you to stop taking the tablets Enap before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead Enap tablets. Enap tablets are not recommended in early pregnancy, and must not be taken if you are pregnant for more than three months , as it may cause serious harm to your baby if used after the third month of pregnancy.

breastfeeding
Tell your doctor if you are breast-feeding or about to start breast-feeding. While taking Enap tablets are not recommended to breastfeed newborn babies ( in the first few weeks after birth ) and especially premature babies . In the case of older babies , your doctor should advise you on the benefits and risks of taking Enap tablets while breastfeeding , compared with other treatments.

Driving and using machines
In individual patients, this drug may cause dizziness or fatigue , especially early in treatment , and thus indirectly transiently reduce the ability to drive and use machines. Until you know how you respond to treatment , do not drive vehicles or operate machinery.

Important information about some of the ingredients of Enap

Enap contains lactose. If your doctor tells you that you have an intolerance to some sugars , consult him before taking this medicine.

3 . HOW TO TAKE Enap ?

Always take Enap exactly as your doctor tells you . If you are not sure, ask your doctor or pharmacist.
The dosage is always adapted to the patient's condition , his needs and the possible use of other drugs. Therefore, it is always determined by the doctor.
Treatment of hypertension: The recommended starting dose is 5 mg once daily. The usual maintenance dose is 10 mg once or twice daily , more than 20 mg once or twice daily.
Treatment of congestive heart failure : The recommended starting dose is 2,5 mg once daily. The usual maintenance dose ranges from 2.5 to 10 mg twice daily , maximum maintenance dose is 20 mg twice daily .
Treatment of dysfunction of the left ventricle : The recommended starting dose is 2,5 mg twice daily. The usual maintenance dose is 10 mg twice daily.
Treatment of secondary hypertension in renal diseases : dosage of Enap is determined by renal function and / or creatinine clearance values . Therefore, it is always determined by the doctor.
Hemodialysis patients: accepted Enap 2,5 mg on the day of hemodialysis , in all the other days the doctor will adjust the dosage according to the level of your blood pressure .
Take the tablets whole with some liquid. They may be taken before, during or after meals. Get used to taking it regularly at the same time each day. Treatment with Enap is continuous unless circumstances arise which require discontinuation. Since you have to take medicine regularly , always provide sufficient tablets for prolonged treatment.

Use in children

Efficacy and safety of the drug in children has not been established yet, so it should not be given to children .

If you take more than the amount Enap

The most common signs of overdose are nausea, rapid pulse , dizziness and fainting due to excessive reduction in blood pressure (hypotension) . In this case lie , keep your head low and call a doctor.
If the patient has eaten a large quantity of tablets and is conscious , try to induce vomiting and call a doctor.
If you forget to take Enap
Do not take a double dose to make up for the forgotten .
If you forget to take a tablet , take it as soon as possible . However, if it is almost time for your next dose , leave the missed tablet and take the next scheduled dose . Never duplicate the dose.

If you stop taking Enap

Upon discontinuation of the treatment blood pressure may be increased again , and the risk of the effects and / or complications of hypertension , especially from the heart, brain and kidneys.
Patients with heart failure may be prepared exacerbation of heart failure and the need arises for hospitalization .
Patients with impaired left ventricular function and without symptoms of heart failure ( eg, difficulty breathing , fatigue little effort , eg . Relaxed after walking , swelling of the ankles and legs) may develop heart failure. In hypertensive patients with renal disease may worsen renal function
If you have any further questions on the use of this product, ask your doctor or pharmacist.

4 . POSSIBLE SIDE EFFECTS

Like all medicines, Enap can cause side effects, although not everybody gets them .

Adverse reactions are classified into the following groups in order of frequency :
Very common : affects more than 1 user in 10
Often affects 1 to 10 users in 100
Uncommon: affects 1 to 10 users in 1000
Rare : affects 1 to 10 users in 10,000
Very rare : affects less than 1 user in 10,000
Not known frequency can not be predicted from the available data

Very common:

- Blurred vision , dizziness , cough ,
- Feeling sick (nausea ), fatigue (asthenia )

Common:

- Depression
- Headache, fainting ( syncope) , angina or chest pain, arrhythmias , rapid heartbeat
- Low blood pressure ( hypotension)
- Difficulty breathing ( dyspnea )
- Diarrhoea, abdominal pain, change in taste .
- Rash, allergic swelling of face, lips , tongue or throat, difficulty swallowing or breathing, fatigue (tiredness )
- Increased level of potassium in the blood , increased levels of creatinine in the blood
Uncommon:

- Anemia
- Excessive reduction of blood sugar levels , confusion, insomnia , sleep disorders , nervousness,
- Increased sensitivity or tingling sensation as a tingling in the hands or feet ( paraesthesia), uncomfortable feeling of skipped beats or palpitations, heart attack and stroke , possibly due to excessive reduction of blood pressure in patients with high risk of excessive decrease blood pressure (also when you stand ) , stroke, probably due to excessive lowering of blood pressure in patients with high risk
- Runny nose , sore throat , hoarseness , asthma,
- Intestinal obstruction , vomiting, inflammation of the pancreas , dyspepsia, constipation, loss of appetite , upset stomach , dry mouth , gastric ulcer or duodenal ulcer , sweating , itching, rash, hair loss , impaired renal function , renal failure, separation of proteins urine
- Inability to get or maintain an erection muscle cramps, flushing , ringing in the ears ( tinnitus) , anxiety , fever , low blood sugar or sodium, high blood urea.

rare:

- Reducing the number of neutrophils ( white blood cells ), decreased hemoglobin ( oxygen carrier in the blood) , decreased hematocrit , decreased platelet count , excessive reduction in the number of white blood cells (agranulocytosis ) , reducing formation of blood cells in the bone marrow , reduced numbers of all blood cells , autoimmune disease , sleep problems , abnormal dreams ,
- Swollen lymph nodes , autoimmune disease , poor blood flow to the fingers and toes, which causes redness and pain ( phenomenon Raynaud), mouth ulcers, sore tongue ,
- Inflammation of the nasal mucosa , the infiltration of the lungs, allergic pneumonia ,
- Hepatic failure, inflammation of the liver , jaundice, various rashes on the skin and / or mucous membranes, reducing the discharge of urine. Breast enlargement in men
- Higher levels of liver enzymes and bilirubin .
Very rare:

- Swelling of the bowel ( intestinal angioedema ) .

Not known:

- Hyponatremia ( caused by SIADH).

Reported the following sets of symptoms : fever , pain in the joints and / or muscles, inflammation and other laboratory results confirming the presence of inflammation.

If any of the side effects gets serious , or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
5 . HOW TO STORE Enap ?

Keep out of reach of children.
Do not use Enap after the expiry date stated on the pack . The expiry date refers to the last day of that month.
Do not store above 30 ° C. Store in the original package to protect from moisture.
Medicines should not be disposed of down the drain or in the trash. Ask your pharmacist how to dispose of medicines no longer required . These measures will help to protect the environment.

6 . ADDITIONAL INFORMATION

What does Enap ?

The active substance is enalaprilov maleate (enalapril maleate). Each tablet contains 2.5 mg, 5 mg, 10 mg or 20 mg enalaprilov maleate, which is equivalent to 1,9 mg, 3,8 mg, 7.6 mg or 15,3 mg enalapril .
The other ingredients of the tablets of 2,5 mg and 5 mg are lactose monohydrate, hydroxypropyl cellulose ( E463 ) , corn starch , sodium hydrogen carbonate, talc ( E553Y ) and magnesium stearate ( E572 ) .
The other ingredients of the tablets of 10 mg are lactose monohydrate, maize starch , sodium hydrogen carbonate, talc ( E553Y ) , magnesium stearate ( E572 ) and red iron oxide (E 172).
The other ingredients of the tablets of the 20 mg tablets are lactose monohydrate, maize starch , sodium hydrogen carbonate, talc ( E553Y ) , magnesium stearate ( E572 ) , red iron oxide ( E172 ) and yellow iron oxide ( E172 ) .

What does and how it looks packaging Enap ?

2,5 mg tablets are white, round and flat .
5 mg tablets are white , round, flat and scored on one side. The score line is not designed for crushing a tablet.
10 mg tablets are red-brown , round, flat and scored on one side. The score line is not designed for crushing a tablet. 20 mg tablets are light orange , round, flat and scored on one side. The score line is not designed for crushing a tablet.

Enap tablets of all strengths are available in the following packages :

Box 20 and 60 from 2,5 mg tablets in a blister pack .
Housing 20 , 30, 60 and 90 tablets of 5 mg, 10 mg and 20 mg per blister pack.

€ 19.00
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