Dulcolax table. 5 mg
Dulcolax table. 5 mg
Each tablet contains 5 mg bisacodyl (bisakodil).
lactose, maize starch, soluble starch, glycerol, magnesium stearate, sucrose, talc, acacia, titanium dioxide eudragit L100 and S100, castor oil, macrogol 6000, iron oxide yellow, white beeswax, carnauba wax, shellac.
Mode of action
Bisacodyl, active ingredient in Dulcolax is a locally acting laxative from difenilmetanovata group. As a non-absorbed is causing water separation (contact laxative) Dulcolax exerts its action after hydrolysis in the colon, causing his motility and accumulation of water and electrolytes into the intestinal lumen.
It is used for constipation (difficulty passing stools).
The product is also indicated in preparation for diagnostic procedures, in pre-and postoperative treatment and in conditions that are required to facilitate defecation. For these indications, the use of Dulcolax should be done under medical supervision.
Dulcolax is contraindicated in patients with volvulus, intestinal obstruction, acute surgical abdomen, such as appendicitis, acute inflammatory bowel disease and severe abdominal pain accompanied by nausea and vomiting, which may be indicative of more serious conditions. Dulcoiax is also contraindicated in severe dehydration and in patients with known hypersensitivity to bisacodyl or any of the other ingredients of the product.
In case of rare hereditary diseases that can lead to incompatibilities with some of the excipients (see warnings and precautions for use), use of the drug is contraindicated.
When using Dulcolax may occur including abdominal discomfort abdominal cramps and abdominal pain (which may be accompanied by nausea and / or vomiting). Observed aa gzdu.cham diarrhea.
Isolated cases of angioneurotic edema and anaphylactoid reactions have been reported in association with the use of Dulcolax.
In high doses Dulcolax concomitant drainage devices or adrenokortikosteroidi may increase the risk of electrolyte imbalance.
Electrolyte imbalance can lead to increased sensitivity to cardiac glycosides.
Warnings and precautions for use
Like all laxatives, Dulcolax should not be used every day or for an extended period of time without being the cause of the constipation.
Prolonged use of high doses can lead to electrolyte imbalance, low potassium level and accelerate the reappearance of constipation.
There have been signs of dizziness and / or syncope in a patient treated with Dulcolax. Available data for these cases suggest that these adverse events are associated with irregular bowel movements (or difficult bowel movements), or vascular-nervous reaction to abdominal pain that may be associated with constipation that caused the patient to resort to the use of laxatives and is not necessarily associated with the use of Dulcolax.
In children Dulcolax should be used only with a prescription.
Each tablet contains 33.2 mg. lactose, resulting in 66.4 mg maximum recommended daily dose for the treatment of constipation in adults and children over 10 years. In preparation for radiographic studies leading to 132.8 mg maximum recommended daily dose. Patients with congenital galactose intolerance eg galactosaemia should not take this medicine.
Each tablet contains 23.4 mg of sucrose, resulting in 46.3 mg maximum recommended daily dose for the treatment of constipation in adults and children over 10 years, in preparation for radiographic studies leading to 93.6 mg maximum recommended daily dose . Patients with congenital fructose intolerance should not take this medicine.
In high doses can be observed watery stools (diarrhea), abdominal cramps and a clinically significant loss of potassium and other electrolytes.
Chronic overdose Dulcolax, as with all medicines can cause chronic diarrhea, abdominal pain, hipokaklemiya (low potassium in the blood), secondary hiperaldostenorizam (increased production of aldosterone - a hormone of the adrenal gland)
and renal disease. Cases of renal tubular damage, metabolic alkalosis (a disorder of acid-base balance) and muscle weakness due to hypokalaemia are described as a result of chronic abuse of laxatives.
Shortly after taking Dulcolax, absorption may be reduced or prevented by inducing vomiting or gastric lavage. You may need fluid replacement and correction of electrolyte imbalance. This is particularly important in the elderly and in children.
In some cases it may require administration of antispasmodics.
Pregnancy and lactation
There are no adequate and well-controlled studies in pregnant women. When used in pregnancy during lengthy observations showed no evidence of adverse or toxic effects. It is not known whether the active ingredient bisacodyl passes into breast milk.
However, as with all medicines, Dulcolax should be taken during pregnancy and lactation only on prescription.
How to take Dulcolax
If no other prescription recommends the following dosages:
Adults and children over 10 years: 1 -2 tablets (5 -10 mg)
Children 4-10 years: 1 tablet (5 mg)
It is recommended to take the tablets at night to induce bowel movements the next morning. The tablets should be swallowed whole with appropriate fluid.
Not recommended duration of taking more than 8 -10 days. The tablets should be taken with products that reduce the acidity of the upper gastrointestinal tract, such as milk, antacids or certain proton pump inhibitors to prevent premature dissolve enteric-coated tablets.
In preparation for diagnostic procedures before surgery
In preparation for diagnostic procedures, in pre-and postoperative treatment and in conditions that are required to facilitate defecation, the use of Dulcoiax should be done under medical supervision.
To achieve complete relief of the intestinal tract, the recommended dosage for adults is 2 to 4 tablets in the evening before the study and 1 suppository administered in the morning.
For children 4 and over 4 years recommended one tablet in the evening and 1 suppository tablet in the morning.
Special precautions for storage
This medicinal product does not require any special storage conditions.
Keep out of reach of children.
Gastro-resistant tablets - 30 tablets.