Doreta. 37.5 mg. 325 mg. 30 tablets

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Doreta. 37.5 mg. 325 mg. 30 tablets
€ 26.00
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Doreta is a combination of two analgesic (pain relief) - tramadol and paracetamol, which act together and relieve your pain.
Doreta is used to treat moderate to severe pain, your doctor determines that you need a combination of tramadol and acetaminophen.

Doreta. 37.5 mg. / 325 mg. 30 tablets

 
 
WHAT Doreta AND WHAT IT IS USED
Doreta is a combination of two analgesic (pain relief) - tramadol and paracetamol, which act together and relieve your pain.
Doreta is used to treat moderate to severe pain, your doctor determines that you need a combination of tramadol and acetaminophen.

2. BEFORE YOU TAKE Doreta
Do not take Doreta if:
you are allergic (hypersensitive) to paracetamol tramadol or any of the other ingredients of Doreta;
drinking alcohol;
taking any medicines that make you sleepy or decrease your concentration, such as opiate drugs to reduce pain such as morphine and codeine;
taking monoamine oxidase inhibitors (MAOIs), e.g. for the treatment. depression or have taken them within the last 14 days;
suffer from severe hepatic impairment;
have epilepsy that is not adequately controlled with medicines you are taking.
Take special care with Doreta if:
Have kidney problems;
Have liver problems or liver disease, or if you notice yellowing of the eyes and skin. This may be due to problems with jaundice or biliary tract;
Have severe breathing difficulty, such as asthma or severe lung problems;
Do according to any medication, including those used for the relief of pain such as morphine;
Have epilepsy or have had seizures or convulsions;
Suffering from head trauma, shock, or a headache which is likely to be, or may not be associated with vomiting;
Taking other medicines containing tramadol and acetaminophen.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

The risk of side effects is increased:
If you are taking medications that may cause convulsions (seizures), such as certain antidepressants and antipsychotics. Risk of having a seizure can be increased if you are taking Doreta at the same time. Your doctor will tell you whether the adoption of Doreta is right for you;
If you are taking any antidepressants, Doreta may interact with these medicines and you may experience symptoms such as involuntary, rhythmic contractions of the muscles, including the muscles that control eye movements, agitation, excessive sweating, tremor, sharpen reflexes, increased muscle tension, body temperature above 38 ° C.
Doreta should not be taken with the following medicines:
Monoamine oxidase inhibitors (MAOIs);
Pain medications that contain opiates such as morphine and codeine.
Doreta is not recommended for adoption with the following medicines:
Carbamazepine is used to treat epilepsy or facial neuralgia (severe bouts of pain in the face);
Opioid analgesics, used to treat moderate to severe pain, e. buprenorphine, nalbuphine and pentazocine.
Under certain circumstances, Doreta can be taken with the following medicines:
Inhibitors of serotonin reuptake inhibitors (SSRI), used for treatment of depression. Reported serotonin in temporal association with the therapeutic use of tramadol in combination with other serotonergic drugs such as selective serotonin reuptake inhibitors of serotonin and triptans. Symptoms of serotonin syndrome may be as confusion, agitation, fever, sweating, ataxia, hyperreflexia, myoclonus and diarrhea;
Some morphine-like drugs, which are used, for example, for prevention or alleviation of cough;
Sedatives such as benzodiazepines;
Sleeping pills such as barbiturates;
Certain drugs used to lower blood pressure;
thalidomide;
Baclofen, used as a muscle relaxant;
Warfarin, used to thin the blood;
Inhibitors of CYP3A4, such as ketoconazole (an antifungal) or erythromycin (antibacterial);
Bupropion used to help people stop smoking;
Tricyclic antidepressants;
Sedatives.
Taking these medicines with Doreta may affect the operation of the Doreta in your body:
Metoclopramide and domperidone used in the nausea and vomiting;
Cholestyramine, used to reduce cholesterol levels in the blood.
Surgery and tests
Tell your doctor or dentist that you are taking Doreta before being subjected to general anesthesia.

Doreta station with food and drink
Doreta can be taken with or without food.
Doreta can lead to drowsiness. Alcohol may make you feel sleepy. Alcohol increases the sedative effect of opioid analgesics may affect concentration when driving or operating machinery, and thus make it dangerous. Avoid taking alcohol or other products containing alcohol.

Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine.
As Doreta is a fixed combination of active substances, including tramadol You should not take this medicine during pregnancy and lactation.

Driving and using machines
Do not drive, operate machinery, or perform other activities that require attention until you know how you act Doreta.

3. HOW TO TAKE Doreta
Always take Doreta exactly as your doctor tells you. If you are not sure, ask your doctor or pharmacist.
The usual starting dose is two tablets. If necessary, it can be accepted and additional doses as recommended by your doctor. The smallest interval between doses should be at least 6 hours.
Do not take more than 8 tablets per day (equivalent to 300 mg of tramadol hydrochloride and paracetamol 2600 mg).
Dosage should be defined in relation to the intensity of your pain and your individual tolerance to pain. Basically you need to take a lower dose of relief from pain.

Severe hepatic or renal impairment (failure) / dialysis patients
Patients with severe hepatic or renal insufficiency should not take Doreta. If in your case the disability is mild to moderate, your doctor may recommend extending the time between doses.
Doreta is not recommended for use in children under 12 years of age.

Elderly
In elderly patients (over 75 years) excretion of tramadol may be delayed. If this applies to you, your doctor may recommend extending the time between doses.
The tablets should be swallowed with a sufficient amount of liquid. Tablets should not be chewed or crushed.
The tablets should be taken for the shortest possible time.
If you think Doreta is too strong (eg, leading to severe drowsiness or difficulty in breathing) or too weak (eg, your pain is not sufficiently relieved), contact your doctor or pharmacist. If you do not get improvement in symptoms, you should consult your doctor.

If you take more than the amount of Doreta
You should seek immediate medical attention in case of overdose, even if you feel well, because of the risk of delayed, serious liver damage.
If you take more than the amount of Doreta may experience severely impaired blood flow to the organs, loss of consciousness up to coma, convulsions, or may experience difficulty in breathing, you do not feel well, vomit, lose weight or experience abdominal pain.

If you forget to take Doreta
Do not take a double dose to make up for a forgotten tablet.
If you miss a dose of Doreta, take your next tablet at the usual time.

If you stop taking Doreta
If you have taken Doreta for a while, you should talk to your doctor if you want to stop because your body may need it. If you suddenly stop taking Doreta may feel bad. You may experience anxiety, agitation, nervousness, insomnia, hyperactivity, tremors and / or upset stomach.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. POSSIBLE SIDE reaction
Like all medicines, Doreta can cause side effects, although not everybody gets them.
Very common (occurring in more than one in 10 individuals treated) side effects may include:
nausea;
dizziness;
Drowsiness.
They are usually mild and do not cause problems.

Common side (occurring in less than one of 10, but more than one in 100 individuals) reactions may involve:
vomiting;
Digestive problems (constipation, gas, diarrhea);
Stomach pain;
Dry mouth;
headache;
trembling;
confusion;
Sleep disorders;
Changes in mood (anxiety, nervousness, euphoria (high spirits all the time));
Increased sweating;
Itching.
Uncommon side (occurring in less than one in 100, but more than treated subjects) reactions include:
High blood pressure, abnormal heart rhythm and heart rate;
Difficulty or pain when passing urine / protein in the urine;
Skin reactions (hives, rash);
Ringing in the ears;
depression;
nightmares;
Hallucinations (hearing, seeing or feeling things that are not there);
Memory loss;
Difficulty in swallowing;
Blood in the stool;
trembling;
Hot flashes;
Chest pain;
Involuntary muscle twitching;
Muscle spasms;
Unusual tingling ("pins and needles");
Shortness of breath;
Elevated liver enzymes.
Rare side effects (occurring in less than 1 in 1,000, but more than 1 per 10,000 treated patients) may include:
Drug addiction;
Seizures, difficulties in the implementation of coordinated movements;
Blurred vision;
Temporary loss of consciousness.
Very rare side effects (occurring in less than 1 in 10,000 treated patients):
Drug abuse.
The following are described side effects reported by people using medicines containing only tramadol hydrochloride or paracetamol. However, if you experience any of these while taking Doreta, you should tell your doctor:
Feeling dizzy when getting up from a lying or sitting position, slow heartbeat, dizziness, changes in appetite, muscle weakness, delayed or reduced breathing, mood changes, change in activity, changes in perception, worsening of asthma;
In some rare cases - skin rash, showing allergic reaction may occur with sudden swelling of the face and neck, difficulty breathing or low blood pressure and dizziness. If this happens to you, stop treatment and consult a doctor immediately. You should not take the drug again.
In rare cases, use of medications such as tramadol can make you dependent on him, making him stop taking difficult.
In rare cases, people taking tramadol for awhile may feel unwell if they stop taking it suddenly. You feel addicted, irritable, nervous or insecure. May be hyperactive, have difficulty sleeping, have stomach or intestinal discomfort. Very few people also experience panic attacks, hallucinations, abnormal sensations such as itching, tingling, numbness and ringing in the ears (tinnitus). If you notice any of these effects or any other unusual symptoms, please tell your doctor or pharmacist as soon as possible.
In exceptional cases, blood tests may reveal certain abnormalities such as low number of platelets in the blood, which may result in bleeding from the nose or gums.

The use of Doreta with medicines used to thin the blood (eg fenoprokoumon warfarin) may increase the risk of bleeding. Any prolonged or unexpected bleeding should be reported to your doctor immediately.

If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

5. HOW TO STORE Doreta
Keep out of reach of children.
Do not use Doreta after the expiry date stated on the carton and blister.
The expiry date refers to the last day of that month.
This medicinal product does not require any special storage conditions.
You should not throw away any medicines via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. FURTHER INFORMATION
What does Doreta
The active substances are: tramadol hydrochloride and paracetamol. Each tablet contains 37,5 mg tramadol hydrochloride equivalent to 32,94 mg tramadol and 325 mg paracetamol.

Other ingredients are:
Tablet core: pregelatinised maize starch, sodium starch glycolate (type A), microcrystalline cellulose (E460) and magnesium stearate (E572).
Film-coating: hypromellose, titanium dioxide (E 171), macrogol 400, iron oxide yellow (E 172), and polysorbate 80.

Doreta looks like and contents of pack
The film-coated tablets are tan, oval, slightly biconvex.
There are cases with 2 tablets (2 tablets in blisters) and 10, 20, 30, 40, 50, 60, 70, 80, 90 and 100 tablets (blisters with 10 tablets).
Not all pack sizes may be marketed.
 
 
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