Depakine Chrono table. 300 mg. 100 tablets

SANOFI AVENTIS
Depakine Chrono table. 300 mg. 100 tablets
€ 37.00
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The active substance in Depakine chrono 300 mg. is sodium valproate. Depakine chrono 300 mg. tablets belong to a group of medicines used to treat epilepsy.



Depakine Chrono table. 300 mg. 100 tablets
 

Depakine Chrono WHAT IS AND WHAT IT IS USED FOR?

The active substance in Depakine chrono 300 mg. is sodium valproate. Depakine chrono 300 mg. tablets belong to a group of medicines used to treat epilepsy.
In adults: Epilepsy
 Primary generalized seizures and epilepsies
 Types of seizures: absence seizures (petit mal), generalized tonic-clonic (grand mal), tonic and atonic seizures, myoclonic seizures, infantile spasms.
 Generalized epilepsies and epileptic syndromes: absence epilepsy, juvenile myoclonic epilepsy (syndrome Janz), epilepsy with generalized tonic-clonic seizures on awakening, photosensitising epilepsies.
 Syndrome Lennox-Gastaut ° West Syndrome
 Focal (partial) epilepsy and seizures with or without secondary generalization.
 
Children: as monotherapy or in combination with other antiepileptic drugs:
Treatment of generalized epilepsy: clonic, tonic, tonic-clonic seizures, absence seizures, myoclonic seizures, atonic seizures, syndrome of Lennox-Gastaut.
 Treatment of partial epilepsy: partial seizures with or without secondary generalized seizures.
 
In children:
 Prevention of febrile convulsions in fever when prevention is considered urgent or risk factors for recurrence of symptoms.
 
Affective psychosis
Treatment and prevention of manic episodes in bipolar disorder.
 

 BEFORE YOU TAKE Depakine Chrono 300

 
Do not take Depakine chrono 300 mg table.
 If you have a proven allergy to sodium valproate (active ingredient 300 mg Depakine chronological table.) Or to any of the ingredients of Depakine chrono 300 mg table.
 If you have active hepatitis or active liver disease
 If you know that you (or someone in your immediate family) data have spent the past hepatitis, especially one caused by drugs
 If you suffer from hepatic porphyria (a rare metabolic disease)
 
If you think you have any of these problems, or if you have any doubt
Consult your doctor before taking Depakine chrono 300 mg table ..
 
Pay special attention to Depakine chrono 300 mg
 If you or your child develop a sudden illness, especially if it is within the first 6 months of treatment, especially if it involves repeated vomiting, extreme fatigue, abdominal pain, drowsiness, weakness, loss of appetite, stomach pain, nausea, jaundice ( yellowing of the skin or whites of the eyes), swelling of the legs or exacerbation of epilepsy or a general feeling of ill health, you should immediately tell their doctor. In a very small number of patients Depakine chrono 300 mg table. can damage the liver (rare pancreas).
 If Depakine chrono 300 mg table is taken from a child under 3 years, while taking other anti-epileptic drugs or have other neurological or metabolic disease and severe form of epilepsy
 Especially if the child is under three years Depakine chrono 300 mg table should not be taken concomitantly with acetylsalicylic acid (aspirin)
 If you have systemic lupus erythematosus (a rare disease)
 If you suffer from any metabolic disorders, especially hereditary enzyme deficiency as a violation of the urea cycle, as it may increase the level of ammonia in the blood
 If you have impaired kidney function. Your doctor may want to monitor the level of valproate or correct dosage
 If a bid is placed on weight because of increased appetite.
 A small number of individuals treated with anti money they make her hurt or kill themselves. If at any time you have these thoughts, immediately contact your doctor.
 
 
Pregnancy
Information for women who could become pregnant
Unplanned pregnancy is not desirable in women receiving 300 mg Depakine chronological table. You must use an effective method of contraception and consult with your doctor before planning a pregnancy.
 
Depakine chrono 300 mg table. does not affect the effectiveness of oral contraceptive tablets.
It is important to discuss pregnancy and epilepsy with your doctor if i have one, with its specialist epilepsy. This is to ensure that you and your doctor agree to take Depakine chrono 300 mg table. if you become pregnant. Babies born to mothers taking 300 mg Depakine chronological table. are more likely to have problems. With proper planning, the likelihood of such events can be reduced. Depakine chrono 300 mg table. may increase the risk of birth defects in the developing baby, such as spina bifida (a condition in which the bones of the spine are not developed properly). Intrauterine fetal disorders, however, can usually be found in the first part of pregnancy by normal controls.
 
Children born to mothers taking Depakine chrono 300 mg tablets during pregnancy may have impaired development and autistic disorders. Talk to your doctor if you are pregnant or think you may be pregnant and you are taking or if Depakine chrono 300 mg table .. Your doctor may adjust your treatment and / or prescribe supplemental folic acid intake. You should not stop taking Depakine chrono 300 mg table. Unless your doctor did not order, because there are serious risks to you and your developing baby because untreated epilepsy. In women taking Depakine chrono 300 mg table during pregnancy may appear bleeding problems in the newborn child.
 
Unplanned pregnancy is not desirable in women receiving antiepileptic drugs. Consult your doctor before planning a pregnancy to get appropriate advice and allow your doctor to adjust your treatment and / or appropriate dosage and to monitor your pregnancy. As soon as you know you are pregnant, tell your doctor.
 
Information for women who became pregnant while taking my Depakine chrono 300 Table
If you become pregnant while taking Depakine tablets, contact your doctor.
 
Breastfeeding
Since only a small amount of Depakine chrono 300 mg table. passes into breast milk in general is not a danger to the child and usually unnecessary diversion. However, discuss with your doctor whether you can breastfeed your baby.
 
Driving and operating machinery
Depakine chrono 300 mg tablets may cause drowsiness or dizziness in some people, particularly early in treatment or in combination with other antiepileptic drugs or benzodiazepines. Check how you react to Depakine chrono 300 mg table. before driving, operating machinery or doing any other activity that may be a risk if you sleepy or dizzy.
 
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
 
Some medicines can affect the effects of 300 mg Depakine chronological table. or vice versa. These are:
 Neuroleptic drugs (used to treat psychiatric disorders
 Medicines to treat depression
 benzodiazepines used as hypnotics or to treat anxiety,
 other medicines used to treat epilepsy, including phenobarbital, phenytoin, primidone, lamotrigine, carbamazepine, topiramate
 Zidovudine (used to treat HIV infection and AIDS)
 mefloquine (used for the treatment and prevention of malaria)
 sapitsilati (aspirin); see. also Children under 3 years. "Before you take 300 ml Depakine chronological table.")
 anticoagulants (used to prevent blood clots)
 cimetidine (used to treat stomach ulcers)
 erythromycin, rifampicin, carbapenems such as imipenem, meropenem and panipenem (antibiotics
 
 
These drugs and some others can be influenced by Depakine chrono 300 mg tablets or they affect its operation. You may need to receive different amounts of your medicine or take other medicines. You'll get advice from your doctor or pharmacist.
 
Your doctor or pharmacist can give you more information on medicines to be careful or avoid while taking Depakine chrono 300 mg tablets.
 
3. HOW TO TAKE Depakine Chrono 300.
Make sure you visit regularly reviews its control. They are very important because you may need dosage adjustment you.
Always Depakine chrono 300 mg table. exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist.
 
Dosage
In general, the initial dose is 10-15 mg / kg per day, corresponding to 2-5 tablets (300 mg) or 1-3 tablets (500 mg) for most patients (60-100 kg). The dose should be titrated to an optimal level and divided into 1-2 daily doses.
In adult dose is generally between 20-30 mg / kg daily, corresponding to 4-10 tablets (300 mg) or 2-6 tablets (500 mg) if the patient is between 60 and 100 kg. If you can not achieve seizure control with this dose, it can be increased. The patient should be monitored closely in case it gets a daily dose greater than 50 mg / kg.
 
For children, the most common dosage is 30 mg / kg daily.
 Depakine should be taken only on prescription by adults and children weighing more than 17 kg.
This formulation is not suitable for children under 6 years (risk of choking). The use of syrup, oral solution (orally) or granular form.
The dose that should be taken is determined by your doctor. It is highly individual.
 
How to take this medicine
 Take this medicine by mouth
 The drug should be taken 1 or 2 times daily, preferably with meals.
 
Duration of treatment
You must follow the prescribed dosage and duration of treatment and you do not stop your treatment without consulting first with your doctor.
If you take more Depakine chrono 300 mg table. Than it should, you should take the following measures in the hospital setting: gastric lavage, maintenance of effective diuresis and monitoring of cardiac and respiratory function. If necessary, very difficult cases dialysis.
Overdose of Depakine chrono 300 mg table. can be dangerous. Immediately contact your doctor or nearest emergency department.
 
 If you forget to take Depakine chrono 300
Do not take a double dose to make up for missed doses. Just keep taking your medication as directed by your doctor.
If you forget to take several doses, contact your doctor.
 
Effects of discontinuation of Depakine chrono 300 mg
 
Do not stop taking Depakine chrono 300 mg tablets. or change the dose without consulting your doctor. If you stop taking the tablets without instructions from your doctor, your condition may get worse.
 

 POSSIBLE SIDE EFFECTS

 
Like all medicines Depakine chrono 300 mg tablets can have side effects in a small number of individuals. They are rarely severe and usually are not. Usually reversible. If you experience any side effects, you may need to get medical help
 Nausea or stomach pain, diarrhea, especially when starting treatment
-Shaking (tremor), drowsiness, unsteadiness when walking
 Skin reactions such as rash,
 Transient hair loss,
 Changes in menstrual cycle
 Hearing problems,
 Allergic reactions
 Swelling of the feet and legs (edema)
 Weight gain
 Kidney problems, dropping in little need or frequent urination
 
Tell your doctor if you notice any of the following serious side effects, yuzhe need to get emergency medical care:
 Change in level of consciousness, abnormal behavior or not associated with more frequent or more severe seizures, loss of interest in the outside world, particularly when taken with phenobarbital and topiramate, or if the dose of Depakine chrono 300 mg tablets suddenly be high rise.
 Repeated vomiting, extreme fatigue, abdominal pain, drowsiness, weakness, loss of appetite, pain in the upper abdomen, nausea, jaundice (pozhyltyavane the skin or whites of the eyes), swelling of the legs or exacerbation of epilepsy or a general feeling impaired health.
 Problems with blood clotting
 Spontaneous bruising or bleeding
Blisters with the skin peeling off
 Severe decrease in white blood cells or bone marrow failure, which sometimes occurs with high fever and difficulty breathing
 Confusion, which may be due to decreased levels of sodium in the blood.
 Induced allergy itchy bumps painful glands (usually around the eyes, lips, throat, and sometimes on the palms and soles)
 Syndrome of drug rash, fever, swollen lymph nodes and suspected violations in other organs
 
Depakine chrono 300 mg table. can also cause low platelets or red blood cells.
If you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
 

 STORAGE OF Depakine Chrono 300 mg

 
Do not take this medicine after the expiry date indicated on the packaging. Depakine chrono 300 mg table. can be damaged if not stored properly (dry below 25 °).
Keep out of reach of children.
 

 ADDITIONAL INFORMATION

 
What Depakine chrono 300 mg tablets
Each tablet Depakine chrono 300 mg contains: Sodium valproate 300 mg
Excipients ::
Ethyl cellulose, hypromellose, silica colloidal hydrated, saccharin sodium polyacrylate, macrogol, talc, titanium dioxide.
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