Defrozyp table. 75 mg. 30 tablets
Defrozyp table. 75 mg. 30 tablets
Defrozyp WHAT IS AND WHAT IT IS USED FOR?
Defrozyp belongs to a group of medicines called antiplatelet medicinal products. Platelets are very small structures, smaller than red or white blood cells that gather together to prevent blood clots that cluster, antiplatelet medicinal products reduce the possibility of blood clots forming (a process called thrombosis).
Defrozyp be taken to prevent the formation of blood clots (thrombi) forming in hardened blood vessels (arteries), a process known as atherothrombosis, which can lead to atherothrombotic events (such as stroke, heart attack, or death).
You have been prescribed Defrozyp to prevent clotting and reduce the risk of these severe events because:
Have a condition of hardening of the arteries (known as atherosclerosis), and
Have had a heart attack, stroke or have a condition known as peripheral arterial disease, or
Have had severe chest pain known as 'unstable angina' or 'myocardial infarction' (heart attack). For the treatment of this condition your doctor may have placed a stent in the blocked or narrowed artery to restore effective blood flow. Have your doctor ordered or acetylsalicylic acid (a substance present in many medicines used to relieve pain and lower fever and to prevent blood clotting).
BEFORE YOU TAKE Defrozyp
Do not take Defrozyp
if you are allergic (hypersensitive) to clopidogrel or any of the other ingredients of Defrozyp;
If you have a medical condition that is causing bleeding such as a stomach ulcer or bleeding in the brain;
if you suffer from severe liver disease;
If you think any of these conditions applies to you, or have doubts about this, check with your doctor before taking Defrozyp.
Take special care with Defrozyp:
If any of the following situations apply to you, you should tell your doctor before taking Defrozyp:
If you are at risk of bleeding, such as
Medical condition, and thus the risk of internal bleeding (like a stomach ulcer)
A blood disorder, which is why you are more prone to internal bleeding (bleeding inside any tissues, organs or joints of your body), recent major trauma
Recent surgery (including dental)
Planned surgery (including dental) in the next seven days
if you have a blood clot in brain artery (ischemic stroke) which occurred in the last seven days
if you are taking any other medication (see 'Taking other medicines').
if you have kidney or liver disease
While taking Defrozyp:
You must tell your doctor if you have a planned surgery (including
You must tell your doctor immediately if you develop a medical condition
which includes fever and bruising of the skin, which can appear as red dots, with or without unexplained extreme tiredness, confusion, yellowing of the skin or eyes (jaundice) (see section 4 'POSSIBLE SIDE EFFECTS').
If you have cuts or hurt, it may take longer than
ordinary time, until the blood stops. This is related to the way your medicine to avoid the possibility of blood clots. This usually does not affect minor cuts, eg. Shaving cuts. However, if you are concerned by your bleeding, you should tell your doctor (see section 4 'POSSIBLE SIDE EFFECTS').
Your doctor may prescribe a blood test.
If any of the side effects gets serious, or you notice other effects not listed in paragraph 4 "POSSIBLE SIDE EFFECTS", please tell your doctor or pharmacist.
Defrozyp is not intended for use by children and adolescents under the age of 18 years.
Taking other medicines:
Some other medicines may influence the use Defrozyp or vice versa. Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
The use of oral anticoagulants (medicines used to reduce blood clotting) with Defrozyp not recommended.
Should specifically tell your doctor if you take:
NSAIDs are usually used to treat painful and / or inflammatory conditions of muscles or joints
heparin or other medicine to reduce blood clotting proton pump inhibitor (eg, omeprazole) for upset stomach.
If you have experienced severe chest pain (unstable angina or heart attack), you may Defrozyp administered in combination with acetylsalicylic acid, a substance present in many medicines used to relieve pain and lower fever. Occasional use of acetylsalicylic acid (no more than 1,000 mg in any 24-hour period) should generally not a problem, but prolonged use in other circumstances should be discussed with your doctor.
Taking Defrozyp with food and drink
Defrozyp can be taken with or without food.
Pregnancy and lactation
It is preferable not to use this product during pregnancy and lactation.
If you are pregnant or suspect that you are pregnant, you should tell your doctor or pharmacist before taking Defrozyp. If you become pregnant while taking Defrozyp, consult your doctor as it is not recommended for use clopidogrel during pregnancy.
While taking Defrozyp, consult with your doctor about breastfeeding your baby.
Please tell your doctor or pharmacist before taking any medicine.
Driving and using machines:
Defrozyp is unlikely to affect your ability to drive or operate machinery.
Important information about some of the ingredients of Defrozyp:
Defrozyp contains lactose.
If your doctor has told you that you have an intolerance to some sugars, please tell your doctor before taking this medicine.
Defrozyp also contains hydrogenated castor oil which may cause stomach irritation or diarrhea.
HOW TO TAKE Defrozyp?
Always Defrozyp exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.
If you have experienced severe chest pain (unstable angina or heart attack), your doctor may give you Defrozyp 300 mg (4 tablets of 75 mg) at baseline. Then, the usual dose is one tablet Defrozyp day taken orally with or without food, at the same time each day.
Defrozyp should take as long as prescribed by your doctor. If you take more than the dose Defrozyp:
Tell your doctor or the emergency room of the nearest hospital, due to an increased risk of bleeding.
If you forget to take Defrozyp:
If you miss a dose Defrozyp but remember within 12 hours after the time of admission, immediately take it and then take your next tablet at the usual time.
If you forget for more than 12 hours, simply take the next single dose at the usual time. Do not take a double dose to make up for forgotten individual doses.
If you stop taking Defrozyp:
Do not stop treatment. Tell your doctor or pharmacist before stopping it.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
POSSIBLE SIDE EFFECTS
Like all medicines, Defrozyp can cause side effects, although not everybody gets them.
Tell your doctor if you have:
Fever, signs of infection or extreme tiredness. This may be due to rare decrease of some blood cells.
Signs of liver problems such as yellowing of the skin and / or eyes (jaundice), whether or not associated with bleeding which appears under the skin as red dots and / or confusion (see section 2, Take special care with Defrozyp ) Swelling in the mouth or skin disorders such as rashes and itching, blisters of the skin. These may be signs of an allergic reaction.
The most common side effects (occurring in 1 to 10 patients in 100) reported for clopidogrel (the active ingredient of the product Defrozyp) is bleeding. Bleeding can occur as bleeding from the stomach or intestine, bruising, hematoma (unusual bleeding or bruising under the skin), nose bleeding, blood in the urine. In a few cases also reported bleeding in the eye, the skull, lungs or joints.
If you experience prolonged bleeding when taking Defrozyp
If you cut or injure yourself, it may take a long time until the blood stops. This is related to the way your medicine works decreased ability to form blood clots. For minor cuts and injuries eg. samoporyazvane, shaving, this does not matter. However, if you are concerned by your bleeding, you should contact your doctor straightaway (see section 2, Take special care with Defrozyp)
Other side effects of clopidogrel (the active ingredient of Defrozyp) are:
Common side effects (affects 1 to 10 users in 100): diarrhea, abdominal pain, indigestion or heartburn.
Uncommon side effects (affects 1 to 10 users in 1,000): Headache, stomach ulcer, vomiting, nausea, constipation, excessive gas in the stomach or intestines, rashes, itching, dizziness, sensation of tingling and numbness.
Rare side effects (affects 1 to 10 patients in 10,000): Vertigo
Very rare side effects (affects less than 1 user in 10,000): jaundice, severe abdominal pain with or without back pain, fever, breathing difficulties sometimes associated with cough, generalized allergic reactions, swelling in the mouth blisters skin, skin allergy, inflammation of the mouth (stomatitis), decreased blood pressure, confusion, hallucinations, joint pain, muscle pain, change in taste perception.
In addition, your doctor can detect changes in the results of the analysis of blood and urine.
If any of the side effects gets serious, or if you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
HOW TO STORE Defrozyp?
Keep out of reach of children.
Defrozyp Do not use after the expiry date stated on the label and carton.
Glass Bottle: Store in the original package to protect from moisture. After opening can be used within three months if stored under 2,5 QC.
PVC / PVDC / Aluminium blister: Store below 30 ° C in the original package to protect from moisture.
Defrozyp Do not use if you notice visible signs of deterioration of the product.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
The active substance is clopidogrel. Each tablet contains 75 mg of clopidogrel (as clopidogrel hydrogen sulphate).
The other ingredients are mannitol (E421), hydrogenated castor oil, hydrogenated microcrystalline cellulose, macrogol 6000 and low-substituted hydroxypropyl cellulose core, and lactose (milk sugar), hypromellose (E464), triacetin (E1518), red iron oxide (E172) , titanium dioxide (E 171), and carnauba wax.