DUOMOX 1000 mg. 20 tablets
Duomox be used to treat infections caused by bacteria sensitive to the action of amoxicillin:
upper respiratory tract, including infections of the ear, nose, throat and sinuses;
Lower respiratory tract exacerbated chronic bronchitis, community-acquired pneumonia;
lower urinary tract: cystitis (infection involving the urinary bladder);
prevention of endocarditis (infection of the heart) operations in the mouth and throat;
early stages of the tick-borne Lyme disease;
Ulcers caused by carriers of Helicobacter pylori.
Duomoks contains amoxicillin, an antibiotic of the penicillin group, which can be disposed of bacteria (sensitive to this antibiotic).
Symptoms (eg temperature) usually disappear within the next few days, but it is essential that the entire prescribed course to be completed.
Talk to your doctor if you feel better in the next few days.
2. BEFORE YOU USE DUOMOX
Do not use DUOMOX
If you are hypersensitive (allergic) to amoxicillin or to any of the excipients Duomoks (see also pt. 6);
If you are hypersensitive (allergic) to other antibiotics penicillin or cephalosporins;
If you suffer from infectious mononucleosis (a viral infection glandular fever);
Together with methotrexate (a drug for suppressing the immune system).
Take special care with Duomoks:
If you suffer from severe and persistent diarrhea or gastrointestinal disorders accompanied by vomiting;
If you suffer from kidney disease. Consult your doctor before taking Duomoks. You may need your doctor to change the dose;
If you suffer from severe allergies or asthma. Duomoks should be taken with caution due to the greater likelihood of allergic reactions;
If during treatment have convulsions. Contact your doctor. Treatment should be discontinued;
If you have infectious mononucleosis (viral infection) or leukemia. You may have an increased risk of skin reactions;
If you have a catheter in the bladder. In such cases, you should not take large amounts of fluids to prevent the formation of crystals in the urine.
This medicine may affect the results of tests for sugar in the urine and blood. Tell your doctor that you are taking the drug if you suffer from diabetes and subject to routine analysis of urine or blood. This is necessary because it may be necessary to use other tests.
In premature infants during the first month after birth should take precautions, should be monitored renal and liver function, and blood counts.
Taking other medicines
Always tell your doctor about other medicines you are taking or have recently taken, including medicines without a prescription. Combinations of different drugs can be harmful to you.
Combining DUOMOX with:
certain chemotherapeutics or antibiotics (such as tetracyclines, macrolides, sulfonamides and chloramphenicol) should not be applied;
disulfiram (a medicine to treat alcoholism) shall not apply;
probenecid (a medicine for the treatment of gout), phenylbutazone, oxyphenbutazone (medicines for the treatment of arthritis) is not recommended;
allopurinol (medicine for gout) can increase the incidence of rash;
sulfasalazine (a medicine to treat intestinal inflammation and rheumatism) may require your doctor to change the dose of sulfasalazine;
methotrexate (a drug for the treatment of blood cancers, rheumatism or psoriasis) is not advisable, since the toxicity of methotrexate can be increased;
digoxin (a medicine for heart disorders) may require the doctor to change the dose of digoxin;
oral contraceptives ("the Pill") can reduce the reliability of their effects. You can also get extra bleeding. It is therefore recommended during treatment with Duomoks and 7 to 14 days after that to use other means of birth control (eg. A condom);
blood-thinning drugs (anticoagulants). Your doctor may order regular blood tests as may be available bleeding tendency.
Taking Duomoks with food and drink
You can take Duomoks dispersible tablets before, during or after a meal, unless your doctor or dentist you do not otherwise prescribed.
Pregnancy and lactation
Always during pregnancy and lactation, consult your doctor or pharmacist before taking any medicine.
Data from a limited number of pregnant women receiving the product indicate no adverse effects of amoxicillin on pregnancy, fetus or newborn. Duomoks can be used during pregnancy and breastfeeding if your doctor has determined that the benefits outweigh the potential risk to the fetus or infant. Please tell your doctor if the baby develops diarrhea, skin rash or candidiasis (infection caused by microscopic fungi). It will consider how to continue treatment because the cause of these reactions may be amoxicillin.
Driving and using machines
This medicine does not affect your ability to drive and use machines.
Important information about some of the ingredients of this medicine
Duomoks contains no sugar, lactose or gluten.
3. HOW TO TAKE DUOMOX
Method of administration
Duomoks dispersible tablets can be taken in two ways:
1. Swallow the tablets whole with a glass of water.
2. Put the tablet in half a glass of water, stir well until its dissolution and the resulting drink sweetened slightly with a slight fruity odor suspension.
If possible, take Duomox tablets distributed at regular intervals. You can take them before, during and after meals, unless your doctor or dentist advises otherwise. If you are unsure about something, ask the doctor who prescribed the drug.
Always take Duomoks as prescribed by your doctor. If you are unsure, ask again your doctor or pharmacist.
The usual dosage varies according to the cause and severity of the infection, the age, weight and renal function of the patient.
For adults and children over 12 years (over 40 kg): the usual dose covers the range from 750 mg to 3 g of amoxicillin daily in two or three doses.
For prevention of heart infections: 2-3 g one hour before surgery.
For children under 40 kg: the daily dose for children is 40-90 mg / kg / day in two to three divided doses * (not more than 3 g / day).
* The data indicate that dosing three times a day was associated with improved efficacy, therefore twice daily dosing is recommended only when the dose has an upper limit of the range.
In severe cases, your doctor may decide to prescribe a non-standard dosage. It is important not to stop treatment prematurely.
The dosage is the same as in adults, except in the presence of impaired renal function.
Patients with kidney disease
It may be necessary for your doctor to reduce the dose.
If you take more dose DUOMOX
Ask your doctor or go to hospital and show package.
May occur gastrointestinal complaints - nausea, vomiting and diarrhea. Possible appearance of other symptoms such as unconsciousness, coma, convulsions and muscle cramps.
If you forget to take DUOMOX
If you forgot to take your tablet in time, you can get it as you remember. However, if it is almost time for your next dose, you do not have to take, but to its previous schedule.
If you stop taking DUOMOX
The average duration of treatment is 7-10 days. Your doctor will decide how long you should take this medicine.
It is important not to stop treatment prematurely. If you stop treatment earlier than required, your condition may get worse.
The absence of fever or other symptoms do not necessarily mean that you are already fully cured. Reason for the feeling of exhaustion is not antibiotic and the infection. Dose reduction or discontinuation of therapy will reduce this feeling, but it will extend the time for which you will recover.
4. POSSIBLE SIDE EFFECTS
Like all medicines, DUOMOX can cause side effects, although not everybody gets them.
Duomoks can cause the following serious side effects are rare (affects less than 1 in 1000 patients), but imposed immediately contact your doctor or go to hospital:
Sudden difficulty in breathing, speaking or swallowing;
Swelling of the lips, tongue, face or neck;
Severe dizziness or collapse;
Heavy and itchy skin rashes, especially in blisters, irritation of the eyes, mouth or genitals;
Yellowing of the skin or whites of the eyes or dark urine and feces fading, which is a sign of liver problems.
Very rarely (less than 1 in 10,000 patients) was observed severe diarrhea lasts a long time and there may be bloody. This may be a sign of serious bowel inflammation.
Other possible side effects
Common (affects 1 to 10 in 100 patients):
Dry mouth and taste disturbances;
Nausea, vomiting, anorexia, diarrhea, stomach pain, bloating, loose stools or itching around the anus. Usually these symptoms disappear on their own in the course of treatment or shortly after discontinuation of treatment. In severe diarrhea should tell your doctor;
Allergic skin reactions in the form of redness / sometimes accompanied by a rash /.
Uncommon (affects 1 to 10 in 1,000 patients):
Vaginal itching, soreness and drafts caused by resistant microbes or fungi;
Superinfection prolonged or repeated use (caused by resistant microbes or fungi);
Moderate and transient increase in liver enzymes.
Rare (affects 1 to 10 in 10,000 patients):
Dizziness, headache, convulsions;
Inflammatory bowel disease (sometimes accompanied by fever or mucus secretion or blood); discoloration of the teeth, which can be removed with a toothbrush;
Anemia (reduction in the number of red blood cells due to increased breakage), increase in the number of certain white blood cells (eosinophilia);
Liver problems and jaundice (expressed as yellowing of the skin and whites of the eyes and darkening of the urine). Stop taking Duomoks and contact your doctor, even if these symptoms occur weeks after treatment;
Inflammation of the kidney accompanied by blood and crystals in the urine, and pain. The crystals in the urine are usually visible only under a microscope and appear as dark urine, and difficulty urinating.
Very rare (affects less than 1 in 10,000 patients):
Reduction of red and white blood cells, platelets reduced prolongation of bleeding time (which can lead to sudden high fever, severe sore throat, oral ulcers, bruising or bleeding). These effects are reversible after discontinuation of therapy;
Discolouration of the tongue.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
5. HOW TO STORE DUOMOX
Keep out of reach of children.
Do not store above 25 ° C. Store in the original container.
Do not use after the expiry date stated on the carton and on the blister with "EXP". The expiry date refers to the last day of that month.
Medicines should not be disposed of in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. FURTHER INFORMATION
The active substance in DUOMOX is amoxycillin trihydrate equivalent respectively 250 mg, 375 mg, 500 mg, 750 mg and 1000 mg of amoxycillin per tablet.
The other ingredients are: carboxymethylcellulose (E466), microcrystalline cellulose (E460), crospovidone (E1202), magnesium stearate (E470b), vanilla essence, tangerine, lemon, saccharin (E954).
DUOMOX looks like and contents of the pack
DUOMOX are dispersible tablets in a glass of water are broken into small, fine particles.