DICYNONE. 250 mg. 2 ml. 1 ampule

DICYNONE. 250 mg. 2 ml. 1 ampule
€ 9.00
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Etamsilatat is a synthetic antihemoragichno and vasoprotective drug which acts in phase I-watts of Hemostasis (interaction between the endothelium and platelets). Increasing platelet adhesion and restoring stability to the capillary wall, it shortens bleeding time and decreased blood loss.

DICYNONE. 250 mg. 2 ml. 1 ampule 

 
 
Antihaemorrhagic
 
INGREDIENTS:
1 ampoule contains :
Active substance:
Etamsylate 250 mg / 250 mg Etamsilat
Excipients:
Sodium bisulfite - 0,8 mg
Water for injections - 2 ml
 
PHARMACEUTICAL FORM :
injection
 
PROPERTIES / ACTION:
Etamsilatat is a synthetic antihemoragichno and vasoprotective drug which acts in phase I- watts of Hemostasis (interaction between the endothelium and platelets) . Increasing platelet adhesion and restoring stability to the capillary wall , it shortens bleeding time and decreased blood loss . Etamsilatat not vasoconstrictor, does not affect fibrinolysis and does not alter the plasma clotting factors . Preclinical Safety Data : Toxicity studies show no toxic effects .
 
INDICATIONS:
In surgery :
Prevention and treatment of pre- , during and post-operative capillary bleeding at all delicate operations and resection thoroughly vascularized tissues : In ENT, Gynecological , urology , dentistry , ophthalmology, plastic and reconstructive surgery.
In pediatrics :
Prevention of periventricular hemorrhage in premature babies.
 
CONTRAINDICATIONS :
Acute form of porphyria , asthma , demonstrated sensitivity to sulphites .
 
DOSAGE AND ADMINISTRATION :
adults
Preoperatively : 1-2 ampoules , intravenously or intramuscularly , 1 hour before surgery.
During surgery : 1-2 ampoules intravenously . The dose is repeated.
Postoperatively, 1-2 ampoules every 4-6 hours to complete the bleeding . Emergency in accordance with the volume of bleeding : 1-2 ampoules intravenously or intramuscularly every 4-6 hours to complete the bleeding .
Local : a cotton bud moistened with the contents of the vial and placed on the affected area. And repeat if necessary , can be combined with systemic ( oral or parenteral) .
children
Preoperatively : 1/2-1 ampoule , intravenously or intramuscularly , 1 hour before surgery.
During surgery : 1/2-1 ampoule , intravenous . The dose is repeated.
Postoperatively 1/2-1 ampoule every 4-6 hours to complete the bleeding .
Emergency in accordance with the volume of bleeding : 1/2-1 ampoule intravenously or intramuscularly every 4-6 hours to complete the bleeding .
Local : a cotton bud moistened with the contents of the vial and placed on the affected area.
And repeat if necessary , can be combined with systemic ( oral or parenteral)
NICU : 10 mg per kg body weight (0,1 ml = 12,5 mg), intramuscular 2 hours after birth , and then every 6 hours for 4 days.
 
SPECIAL WARNINGS AND PRECAUTIONS FOR USE:
In the parenteral administration of 250 DITSINON may provoke a decrease in blood pressure. Careful to monitor patients with unstable blood pressure or hypotension ( See " Side effects). No evidence of such risks oral .
 
Pregnancy and lactation :
Category C: There are no studies on the impact of DITSINON 250 pregnant women or animals. Do not apply during the first trimester of pregnancy , in II and III quarter - only if the expected therapeutic benefits outweigh the potential risk to the fetus. Due to lack of data on the passage of DITSINON 250 in breast milk, breastfeeding is not recommended during application. Otherwise, treatment is stopped .
 
Drive and use machines
DITSINON 250 has no influence on the ability to drive and use machines.
 
SIDE EFFECTS :
In some cases, the parenteral administration induces a fall in blood pressure . Normal values returned for several hours.
In most cases, these symptoms disappear spontaneously , but if you continue , however , the dose should be reduced or discontinued treatment.
Ampoules contain 250 DITSINON sodium bisulfite as the antioxidant , which can cause allergic reactions, nausea and diarrhea in susceptible individuals . Allergic reactions can lead to anaphylactic shock and life-threatening asthma attack. No data on the frequency , but is assumed to be low, such as sodium bisulfite sensitivity is observed much more frequently in asthmatics than in neastmatitsi .
( See "Contraindications" and "Precautions" ) In case of hypersensitivity , use of DITSINON 250 vials must be immediately discontinued.
 
DRUG INTERACTIONS :
Sulfite in ampoules of 250 DITSINON deactivating the operation of thiamine ( vitamin B1)
If necessary injections dextran DITSINON 250 must be injected in advance .
 
OVERDOSE :
Manifestations of overdose has been reported . In case of overdose symptomatic treatment should be initiated .
 
PHYSICAL AND CHEMICAL INCOMPATIBILITY:
There are known in the art .
 
SHELF LIFE :
Store in original package , Dicynone 250 has a shelf life 5 years
 
Storage:
Ampoules should be protected from light.
Do not use the solution if it is colored .
Do not use after the expiry date stated on the package .
 
PACKING:
Cartons of 4 to 100 colorless glass ampoules , each with 2 ml.
 
 
 
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