DETRUSITOL 2 mg. 28 tablets
DETRUSITOL 1 mg tablets are white and marked with dagichki above and below the letters TO. DETRUSITOL 2 mg tablets are white and marked with dagichki above and below the letters DT.
• DETRUSITOL belongs to a class of antimuscarinic drugs that relax the muscles of the bladder
• DETRUSITOL tablets of 1 mg and 2 mg are available in the following packaging: blister packs containing 28 or 56 tablets (two or four blisters of 14 tablets each)
DETRUSITOL is intended to treat the symptoms of the syndrome, overactive bladder, i.e. when you feel the need to go quickly to the bathroom without you experienced pre-need, have the need of going to the toilet frequently and / or unable to get to the toilet in time and wetting.
2. BEFORE YOU TAKE DETRUSITOL
You should not DETRUSITOL:
• If you suffer from impaired emptying of the bladder.
• If you suffer from glaucoma (high pressure and pain in the eyes)
• If you suffer from myasthenia gravis (a disorder of neuromuscular function).
• If you have ever experienced hypersensitivity to tolterodine or any of the excipients in the formulation of this medicine, described above.
• If you have severe ulcerative colitis or toxic megacolon (acute dilation of the colon associated with amoebic or ulcerative colitis).
Be especially careful with DETRUSITOL
• If you have severe swelling and pain in the abdomen, affecting passage and digestion of food.
• If you have difficulty urinating and thinning of the jet.
• If you have liver problems. The doctor will reduce the usual dose.
• If you have kidney problems. The doctor will reduce the usual dose.
• If you have autonomic neuropathy (problem associated with the nervous system, which sometimes occurs with diabetes and can lead to diarrhea, impotence or low blood pressure).
• If you have a hiatus hernia (part of the stomach goes up through the diaphragm).
• If you have suffered or are suffering from severe constipation.
Caution is required if:
• you breach ECG (heart recording), known as QT-interval prolongation
• you have a slow heart rate (bradycardia)
• suffer from heart disease such as cardiomyopathy (heart muscle damage), myocardial ischemia (reduced blood flow and oxygen supply to the heart muscle), arrhythmia (irregular heartbeat) or heart failure
• have abnormalities of potassium, calcium or magnesium in the blood
• taking any medicine for the treatment of arrhythmia (irregular heart beat) Ask your doctor or pharmacist before starting treatment if you think any of the above things apply to you.
Pregnancy and lactation
DETRUSITOL generally should not be used if you are pregnant or breastfeeding, -Because it can affect the baby. Women of childbearing age can take DETRUSITOL only if they use effective contraception.
Driving and using machines
DETRUSITOL can sometimes cause dizziness, fatigue and blurred vision in a small number of patients (see "Possible side effects"). This may impair your ability to concentrate and react. No need to plan driving or operating hazardous machinery until you are sure that this does not apply to you. If you develop symptoms, do not drive or operate machinery during treatment with DETRUSITOL.
Taking other medicines
Tell your doctor if you are taking other medicines. Some of them may interact with DETRUSITOL, eg., Macrolide antibiotics (erythromycin and clarithromycin), medicines to treat fungal infections or protease inhibitors, HIV (ritonavir) .Kazhete your doctor if you are taking any medicine to treat arrhythmia (irregular heart beat).
3. HOW TO TAKE DETRUSITOL?
The usual dose is 2 mg twice daily except in patients with impaired renal or hepatic function receiving the recommended dose is 1 mg twice daily. Swallow the tablet whole. Food intake has no effect on the drug.
DETRUSITOL not recommended for children.
Your doctor will tell you how long the treatment with DETRUSITOL. Do not stop treatment early because you do not see an immediate effect. Your bladder will need some time to adapt. Finish the course of tablets prescribed by your doctor. If you have not found an effect then discuss this with your doctor.
If you take more than the required amount DETRUSITOL:
Do not take more tablets than you have been told by your doctor. If you accidentally swallow too many tablets, seek immediate medical help from your doctor or ambulance.
If you forget to take DETRUSITOL
If you forget to take your tablet at the usual time, take it as soon as you remember unless it is time to take the next tablet. Do not take more than one dose per day. Continue to take your tablets as prescribed.
4. POSSIBLE SIDE EFFECTS
Like all medicines DETRUSITOL can also have side effects. Due to the pharmacological action of the drug DETRUSITOL can cause dry mouth, burning in the region of the heart and dry eyes. The most common adverse reaction associated with DETRUSITOL is dry mouth, which can occur in 35% of patients. If any of these side effects is disturbing to you, please tell your doctor, which could reduce your dose. If severe or prolonged, call your doctor as soon as possible.
Common side effects> 1% and <10% (less than one in 10, but more than one in 100 patients)
• constipation, abdominal pain, burning in the heart area (stomach discomfort after meals)
• dizziness, headache
• reduced formation of tear secretion (dry and irritable eyes)
• changed sense (tingling)
• blurred vision
• chest pain
• flatulence, vomiting
• dry skin.
Uncommon side effects
• swelling of the ankles
• allergic reactions
• inability to empty the bladder
Rare side effects:> 0.01% to <0.1% (less than one in 1000 but more than one in 10 000 patients):
• rapid heartbeat
Other side effects that have been reported with the use of medicines containing the same drug tolterodine, are:
• severe allergic reactions (very rare)
• heart failure (very rare).
Palpitations and irregular heartbeat (rare) are known side effects of this type of medicine. If there are any complaints or have increasing difficulty in urination or confusion, the drug should be stopped and you should seek emergency medical care. If you notice any side effects not mentioned in this leaflet, please tell your doctor shi pharmacist.
6. STORING DETRUSITOL
DETRUSITOL Keep out of reach of children. Store at room temperature (below 25 ° C) .Ne DETRUSITOL use after the expiry date. Use before the date printed on the label / carton.
How often encounter problems with bladder?
Over 3 million people in the UK suffer from various problems of the bladder.
What else can you do?
Exercise of the bladder - this will help you regain control over the bladder, so that you can extend the time until the next urination. You can do this by restrained as much as possible before you urinate.
Exercises for the pelvic floor - they strengthen the muscles, which can help to "hold" long before urinating. This would help you if you miss when coughing when laughing or sneezing. Contact your doctor if you need details of those exercises.