Co VALSAKOR. 160 mg. 12.5 mg. 28 tablets

Co VALSAKOR. 160 mg.  12.5 mg. 28 tablets
€ 14.00
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Co-Valsakor tablets contain two active substances called valsartan and hydrochlorothiazide. Both substances help to control high blood pressure (hypertension).
Valsartan belongs to a class of medicines known as, tangiotenzin II receptor antagonist ', which help to control high blood pressure. 

Co-VALSAKOR. 160 mg. / 12.5 mg. 28 tablets

 
 
WHAT CO-VALSAKOR AND WHAT IT IS USED
Co-Valsakor tablets contain two active substances called valsartan and hydrochlorothiazide. Both substances help to control high blood pressure (hypertension).
Valsartan belongs to the class of drugs known as, tangiotenzin II receptor antagonists ", which help to control high blood pressure. Angiotensin II is a substance in the body, which causes constriction of blood vessels, thereby causing an increase in blood pressure. Acts as Valsartan block the effect pa angiotensin I. As a result, blood vessels relax and cc blood pressure is lowered.
Hndrohlortiazid belongs to a group of medicines called thiazide diurstitsi (also known as "water tablets"). Hydrochlorothiazide increases urine excretion pa, which also lowers blood pressure.
Co-Valsakor used to treat high blood pressure is not adequately controlled by either compound alone.
High blood pressure increases the workload of the heart and the arteries. If left untreated, it can damage the blood vessels of the brain, heart and kidneys, and may lead to stroke, heart failure or renal failure. High blood pressure increases the risk of heart attacks. Lowering elevated blood pressure reduces the risk of development of these diseases.
2. BEFORE YOU TAKE CO-VALSAKOR
Do not take Co-Valsakor
- If you are allergic (hypersensitive) to valsartan, hydrochlorothiazide, sulfonamide derivatives (chemicals associated with hydrochlorothiazide) or any of the other ingredients of Co-Valsakor,
- If you are more than 3 months. (It is also better to avoid taking Co-Valsakor in early pregnancy.
- If you have severe liver disease
- If you have severe kidney disease
- If you are unable to urinate,
- If you receive an artificial kidney
- If the amount of potassium or sodium in the blood is lower than normal, or if the level of calcium in the blood is higher than normal, in spite of the treatment, if you have gout.
If any of these apply to you, do not take this medicine and talk to your doctor.
Take special care with co-Valsakor
- If you are taking potassium-sparing medicines, potassium supplements, salt substitutes containing potassium, or other drugs that increase the amount of potassium in the blood, such as heparin. You may need your doctor to regularly check the amount of potassium in the blood.
- If you have low potassium levels in the blood.
- If you have severe diarrhea or vomiting.
- If you are taking high doses of water tablets (diuretics).
- If you have severe heart disease.
- If you have a narrowing of the renal artery.
- If you have recently received a new kidney transplant.
- If you suffer from aldosteronism. This is a disease in which your adrenal glands produce too much of the hormone aldosterone. If this applies to you, the use of co-Valsakor not recommended. If you have liver or kidney disease.
- If you have fever, rash and joint pain, which can be signs of systemic lupus erythematosus (CJIE, what is called an autoimmune disease).
- If you have diabetes, gout, high levels of cholesterol and fats in the blood.
If you have had allergic reactions to the use of other drugs to lower blood pressure, which are members of this class (angiotensin II receptor antagonists), or if you have an allergy or asthma
It can cause increased skin sensitivity to the sun.
Using Co-Valsakor in children and adolescents (under 18 years) is not recommended.


You should tell your doctor if you think you are (or might become) pregnant. Co-Valsakor not recommended in early pregnancy, and must not be taken if you are pregnant for more than three months, as it may cause serious harm to your baby if used at that stage.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any medicines, including medicines obtained without a prescription
The treatment effect of co-Valsakor may be affected if it is taken with certain other medicines. You may need to change the dose, to take other precautions, or in some cases to stop taking one of the medications. This especially applies to the following medicines: lithium, a medicine used to treat certain types of mental illness, drugs that affect or can be affected by the levels of potassium in the blood, such as digoxin, a drug to control heart rhythm, some antipsychotic drugs , drugs which can increase the amount of potassium in the blood, such as potassium supplements, potassium-containing salt substitutes, potassium sparing drugs, heparin, drugs which can reduce the amount of potassium in the blood, such as corticosteroids, some laxatives diuretics (water tablets), medicines for gout, such as allopurinol, therapeutic vitamin D and calcium supplements, medicines for diabetes (oral agents or insulin), other drugs to lower blood pressure, such as beta-blockers or methyldopa or such that tighten your blood vessels or for stimulation of the heart, such as e. noradrenaline or adrenaline
drugs that increase blood sugar levels, as diazoxide, drugs for the treatment of cancer, such as methotrexate or cyclophosphamide, analgesics, drugs for the treatment of arthritis, muscle relaxants such as tubocurarine, anti-cholinergic drugs such as atropine or biperiden , amantadine (a drug used to prevent the flu), cholestyramine and colestipol (medicines used for the treatment of high levels of
fats in the blood), ciclosporin, a medicine used after organ transplants to prevent organ rejection, some antibiotics (tetracycline), anesthetics and sedatives, carbamazepine, a medicine to treat seizures.
Taking Co-Valsakor with food and drink
You can accept Co-Valsakor with or without food.
Avoid drinking alcohol until you have talked with your doctor. Alcohol can make the blood pressure to drop more and / or increase your risk of dizziness or fainting.
 
Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine.
Pregnancy
You should tell your doctor if you think you are (or might become) pregnant. Your doctor will normally advise you to stop taking Co-Valsakor before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Co-Valsakor. Co-Valsakor not recommended in early pregnancy, and must not be taken if you are pregnant for more than three months, as it may cause serious harm to your baby if used after the third month of pregnancy.
Breastfeeding
Tell your doctor if you are breast-feeding or before breast-feeding.
Co-Valsakor not recommended for mothers who are breastfeeding and your doctor may stop your treatment for you if you want to breast-feed, especially if your baby is born prematurely novorodenoili.
Driving and using machines
Before driving a vehicle, use tools or operate machinery, or perform other activities that require concentration, make sure you know how you affect Co-Valsakor. Like many other medicines used to treat high blood pressure, Co-Valsakor can cause dizziness and affect the ability to concentrate.
Important information about some of the ingredients of Co-Valsakor
Co-Valsakor contains lactose. If your doctor tells you that you have an intolerance to some sugars, contact your doctor before taking this medicine.
3. HOW TO CO-VALSAKOR
Always take Co-Valsakor exactly as your doctor tells you. If you are not sure, ask your doctor or pharmacist.
People with high blood pressure often do not notice any signs of this problem. Most may feel quite normal. Therefore it is very important for you to see your doctor, even if you feel well.
Your doctor will tell you exactly how many tablets Co-Valsakor accept. Depending on how you respond to treatment, your doctor may suggest a higher or lower dose.
The usual dose of Co-Valsakor is one tablet per day.
Do not change your dose or stop taking the tablets without consulting your doctor.
The drug should be taken at the same time each day, usually in the morning.
You can take Co-Valsakor with or without food. Swallow the tablets with a glass of water.
If you take an overdose of Co-Valsakor
If you have severe dizziness and / or feeling that faint, lie down and contact your doctor immediately.
If you accidentally take too many tablets, contact your doctor, pharmacist or nearest hospital.
If you forget to take Co-Valsakor
If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the dose. Do not take a double dose to make up for missed.
If you stop taking Co-Valsakor
Discontinuation of co-Valsakor can lead to worsening of high blood pressure. Do not stop taking your medicine unless your doctor has told you.

If you have any further questions on the use of this product, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Co-Valsakor can cause side effects.
These side effects may occur with certain frequencies, which are defined as follows:
Very common: affects more than 1 user in 10 Total: affects 1 to 10 users in 100
Uncommon: affects 1 to 10 users in 1000 Rare: affects 1 to 10 users in 10,000
Very rare: affects less than 1 user in 10,000 Not known: frequency can not be estimated from available data. Some side effects can be serious and need immediate medical attention:
You should consult with your doctor immediately if you experience symptoms of angioedema, such as:
swelling of the face, tongue or pharynx, difficulty in swallowing, hives and difficulty in breathing.
Other side effects include:
Uncommon
Cough
Low blood pressure Svetoboyazan
Dehydration (with symptoms of thirst, dry mouth and tongue, often urination, dark urine, dry skin) Aching muscles Fatigue
Tingling or numbness Blurred vision
Noise (such as hiss, hum) ears
Very rare
Dizziness Diarrhea
Joint pain
Not known
Dyspnoea
Severely decreased urine output
Low sodium in the blood (sometimes with nausea, fatigue, confusion, malaise, seizures)
Low levels of potassium in the blood (sometimes with muscle weakness, muscle spasms, abnormal heart rhythm)
Low level of white blood cells (with symptoms such as fever, skin infections, sore throat or mouth ulcers due to infections, weakness) increased level of bilirubin in the blood (which can, in severe cases, enhance yellowing of the skin and eyes)
Increases in blood urea and creatinine (which can focus on impaired renal function)
Increasing the level of uric acid in the blood (which can, in severe cases, can accelerate the onset of gout) Syncope (fainting).
Adverse reactions reported for valsartan or hydrochlorothiazide alone were observed in co-Valsakor:
Valsartan
Uncommon
Feeling dizzy Abdominal pain
Not known
Skin rash with or without itching, along with some of the following signs and symptoms: fever, joint pain, muscle pain, swollen lymph nodes and / or flu-like symptoms
Rash, purplish-red spots, fever, itching (symptoms of inflammation of blood vessels)
Low level of blood platelets (sometimes with unusual bleeding or Sissy skin)
High levels of potassium in the blood (sometimes with muscle spasms, abnormal heart rhythm)
Allergic reactions (with symptoms such as rash, itching, hives, difficulty
breathing or swallowing, dizziness)
Swelling of the face and throat; rash; itch
Increase in liver enzymes
Decreased hemoglobin and reducing the percentage of red cells in the blood (both in the more severe cases, accelerate the development of anemia) Renal insufficiency.
Common Hidrohdorotiazid
Itchy rash and other types of rash Slightly Decreased appetite nausea and vomiting weakness, fainting when standing impotence.
Rare
Blistering and swelling of the skin (due to increased sensitivity to the sun) Constipation, discomfort in the stomach or intestines, liver problems (yellowing of the skin or eyes) Irregular heart rhythm sleep disorders Headache sad mood (depression)
Low level of blood platelets (sometimes with bleeding or injury under the skin).

Very rare
Inflammation of blood vessels, with symptoms such as rash, purplish-red spots, fever
Itching or red skin Blisters on the lips, eyes or mouth, skin peeling Fever
Facial rash associated with joint pain Muscle disorders
Fever (cutaneous lupus erythematosus) Severe pain in the upper abdomen; absence or low levels of diff cells

Severe allergic reactions Difficulty breathing Infection of the lungs; shortness of breath.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
5. HOW TO STORE CO-VALSAKOR
Keep out of reach of children. Do not store above 30 ° C.
Store in the original package to protect from light and moisture.
Do not use valsartan / hydrochlorothiazide after the expiry date which is stated on the label after EXP. The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. Zr these measures help to protect the environment.
6. FURTHER INFORMATION
What does co-Valsakor
The active substances are: valsartan and hydrochlorothiazide (valsartan, hydrochlorothiazide). Each Co-Valsartan 80 mg/12, 5 mg film-coated tablet contains 80 mg of valsartan and hydrochlorothiazide 12,5 mg.
Each Co-Valsartan 160 mg/12, 5 mg film-coated tablet contains 160 mg valsartan and 12.5 mg hydrochlorothiazide.
Each Co-Valsartan 160 mg/25 mg film-coated tablet contains 160 mg valsartan and 25 mg hydrochlorothiazide.
Other ingredients are: microcrystalline cellulose, lactose monohydrate, magnesium stearate, croscarmellose sodium, povidone K-25, silica, colloidal anhydrous in the tablet core and hypromellose, titanium dioxide (E 171), macrogol, red iron oxide (72 1), yellow iron oxide (E 172) - only in 80 mg/12, 5 mg and 160 mg/25 mg tablets - in the film coating.
 
 
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