Clindamycin Table. 600 mg. 30 table

Clindamycin Table. 600 mg. 30 table
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MIR-clindamycin 600 mg is an antibiotic from the group of lincosamides. It is used to treat infections caused by organisms susceptible to clindamycin [eg susceptible anaerobic bacteria susceptible strains of aerobic Gram-positive bacteria (streptococci, staphylococci, pneumococci) and susceptible strains Chlamydia trachomatis]:



Clindamycin Table. 600 mg. 30 table
 

WHAT-clindamycin 600 mg MIR AND WHAT IT IS USED

MIR-clindamycin 600 mg is an antibiotic from the group of lincosamides. It is used to treat infections caused by organisms susceptible to clindamycin [eg susceptible anaerobic bacteria susceptible strains of aerobic Gram-positive bacteria (streptococci, staphylococci, pneumococci) and susceptible strains Chlamydia trachomatis]:
 infections of bones and joints;
 ear, nose and throat;
 Dental and dental infections;
 infections of the lower respiratory tract;
 intra-abdominal infections. gynecological infections;
 infections of skin and soft tissue;
 scarlet fever.
 
In case of severe infections, treatment should begin with parenteral (intravenous) administration of clindamycin containing products.
 

 BEFORE YOU TAKE MIR-clindamycin 600 mg

 
Do not take Clindamycin 600 mg-MIR
 
 if you are allergic (hypersensitive) to clindamycin or any other component of the MIR-Clindamycin 600 mg film-coated tablets (listed in section 6 'What Clindamycin 600 mg-MIR ")
 if you are allergic (hypersensitive) to lincomycin.
 
Take special care with MIR-Clindamycin 600 mg
 
MIR-clindamycin 600 mg should be administered with caution in:
 hepatic dysfunction;
 disturbances in neuromuscular conduction (eg, myasthenia gravis: painful muscle weakness or Parkinson's disease: a vibrating paralysis etc.);
 previous gastrointestinal illness (eg previous inflammation of the colon).
In case of long-term treatment (more than three weeks) should be periodically Blood counts and liver function and kidney.
 
In the event of severe and persistent diarrhea during treatment with clindamycin, stop taking the medicine and tell your doctor.
Prolonged and repeated use of clindamycin can lead to infection of the skin and mucous membranes of microbes against which MIR-Clindamycin 600 mg is inefficient and populating a blastomitseti. MIR-clindamycin 600 mg should be administered in case of acute respiratory infection caused by viruses.
Klindamshnsh-MIR 600 mg is ineffective in the treatment of meningitis, as achieved concentrations of clindamycin in cerebrospinal fluid-spipalnata not sufficient for treatment.
 

Taking other medicines

 
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
MIR-clindamycin 600 mg should not be combined with macrolide antibiotics (eg, erythromycin) because mutual suppression efficiency.
 
Cross resistance has been demonstrated between clindamycin, which is an active ingredient-MIR Clindamycin 600 mg and containing lincomycin medicines.
 
MIR-clindamycin 600 mg may increase the effects of muscle-relaxing drugs (eg ether, tubocurarine and pankuroniev bromide) due to its ability to neuromuscular blockade. This effect can lead to unexpected, life-threatening events during surgery.
 
The efficacy of oral contraceptives when taken together with MIR-Clindamycin 600 mg is not guaranteed. For this reason, you should use any additional methods of contraception.
 
Taking Clindamycin-MIR 600 mg with food and drink
 
You may take this medicine with or without food.
 

Pregnancy and lactation

 
For use during pregnancy and lactation should be considered carefully the benefit / risk. So far, studies in humans showed no teratogenic effect of clindamycin.
In infants can be observed sensitization (development of hypersensitivity), diarrhea and mucosal colonization with blastomitseti.
Ask your doctor or pharmacist before taking any medicine.
Driving and operating machinery
MIR-clindamycin 600 mg did not affect the ability to drive or operate machinery.
 

 HOW TO MIR-clindamycin 600 mg

 
Always take Clindamycin-MIR 600 mg exactly as your doctor tells you. If you're not sure, ask your doctor or pharmacist.
Tablets should be swallowed whole (not chewed or crushed) with sufficient liquid (eg a glass of water). It is recommended that tablets be taken at several doses distributed throughout the day, preferably every 6 to 8 hours.
If your doctor has prescribed for other Clindamycin-MIR 600 mg, are valid instructions below. Please follow the instructions for use, as otherwise the MIR-Clindamycin 600 mg will not have the desired effect.
Depending on the severity and location of the infection, adults and children over 14 years of age take 1 to H tablets Clindamycin MIR-600 mg (equivalent to 0.6 g to 1.8 g clindamycin) daily. The daily dose should be divided in 3-4 doses.
Dosage in children 6 to 14 years old
 
From 8 to 25 mg / kg daily in 3-4 divided doses. This formulation is not suitable for children under 6 years of age.
Dosing in patients with hepatic impairment
In patients with moderate to severe hepatic impairment time for which the medicinal product is broken in half in the body increases. Dose reduction is usually not necessary if Clindamycin-MIR 600 mg is administered every eight hours. However, in patients with severe hepatic impairment concentration of drug in the blood should be monitored. According to the results it is necessary to resort to reducing the dose or alternatively extending the time between doses.
Dosage in patients with renal impairment
In patients with renal impairment, time release half the quantity of the product is also extended by reducing the dose in most cases is not necessary. However, in patients with severe renal impairment or cessation of urine output (anuria), the concentration of drug in the blood should be monitored. In accordance with the results is necessary to reduce the dose or prolonging the time between doses of 8 to 12 hours.
Dosage in hemodialysis patients
Clindamycin is not removed by hemodialysis. So before and after dialysis is not necessary to change the previous dosage.
If you take more than the dose-MIR Clindamycin 600 mg
Tell your doctor or pharmacist immediately. If possible, take your medicine and this leaflet with you.
If you forget to take Clindamycin 600 mg-MIR
 
Usually the symptoms are not aggravated, especially if a dose was missed. Continue treatment with the prescribed dosage and administration forgotten with a double dose. But please remember that MIR-Clindamycin 600 mg can be safe and effective only if taken regularly.
If you stop taking Clindamycin 600 mg-MIR
In case of side effects, your doctor will inform you about possible emergency and will advise if other medicines are appropriate for your treatment. Please do not stop your treatment in any way, without you consult with your doctor.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
 

POSSIBLE SIDE EFFECTS

 
Like all medicines, MIR-Clindamycin 600 mg can cause side effects, although not everybody gets them.
Side effects may occur with certain frequencies, which are defined as follows:
 Very common: affects more than 1 user in 10
 Common: affects 1 to 10 users in 100
 Uncommon: affects 1 to 10 users in 1,000
 Rare: affects 1 to 10 users in 10,000
 Very rare: affects less than 1 user in 1000
 Not known: frequency can not be estimated from available data.
 
Blood and lymphatic system
Rare: Thrombocytopenia, leukopenia, eosinophilia, neutropenia or granulocytopenia (disturbances in a number of different blood cells and platelets in the blood).
Gastrointestinal Disorders
Common: Stomach discomfort, nausea, vomiting and diarrhea.
Rare: Oesophagitis (inflammation of the esophagus), stomatitis (inflammation of mouth) and glossitis (inflammation of the tongue).
Unknown: Pseudomembranous colitis (an infection of the intestine caused by the bacterium Clostridium difficile).
 
Nervous System
Rare: Effect of neuromuscular blocking (breach of transmission of impulses from nerves to muscles).
 
Skin and subcutaneous tissue disorders
Rare: vaginitis (inflammation of the vulva in females), and flaking.
Very rare: Erythema multiforme eksudativum (such as Stevens - Johnson syndrome) and Lyell's syndrome (the latter two are serious skin reactions with blistering of the skin, mouth, eyes and genitals).
Common: Rash, pruritus, and urticaria (large red and thickened areas of the skin).
Disorders of the musculoskeletal system and connective tissue
Not known: arthralgia (joint pain).
Hepatobiliary disorders
Rare: jaundice, abnormal liver function tests.
Immune System
Unknown: Anaphylactic shock, Quincke's edema (swelling of the mouth, tongue and throat).
 

 HOW TO STORE MIR-clindamycin 600 mg

 
Keep out of reach of children.
Do not store above 30 ° C and protected from light
Do not use Clindamycin-MIR 600 mg after the expiry date stated on the carton and blister after "EXP". The expiry date refers to the last day of that month
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
 

 ADDITIONAL INFORMATION

 
What MIR-Clindamycin 600 mg
 The active substance is clindamycin. 1 tablet contains 688 mg of Clindamycin hydrochloride, equivalent to 600 mg of clindamycin.
 The other ingredients are: microcrystalline cellulose, mannitol, talc, magnesium stearate, crospovidone, anhydrous silica, titanium dioxide (E 171), macrogol, butyl methacrylate-(2-dimethylaminoethyl) methacrylate-copolymer metakrilatmetil (1:2:1).
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