Ciprobay 500 mg. 10 tablets
Ciprobay contains the active ingredient ciprofloxacin. Ciprobay is an antibiotic of the fluoroquinolone. Ciprobay works by killing the bacteria that caused the infection. Act only certain strains of bacteria.
Ciprobay is used in adults to treat the following bacterial infections:
respiratory tract infections;
prolonged or repeated ear infections or sinus;
urinary tract infections;
infections of the genital tract in men and women;
infections of the gastrointestinal tract, and abdominal infections;
infections of skin and soft tissue;
infections of bones and joints;
Prevention of infection with Neisseria meningitidis;
inhalation of anthrax spores.
Ciprobay can be used in patients with low numbers of white blood cells (neutropenia), which have an elevated temperature, which is suspected to be caused by a bacterial infection.
If you suffer from severe infection or infection caused by more than one type of bacteria, you may be given additional antibiotic treatment than Ciprobay.
Children and adolescents
Ciprobay use in children and adolescents under specialist medical supervision for the treatment of the following bacterial infections:
lung and bronchial infections in children and adolescents suffering from cystic fibrosis;
complicated urinary tract infections, including infections that have reached the kidneys (pyelonephritis);
inhalation of anthrax spores.
Ciprobay may also be used to treat other specific severe infections in children and adolescents when your doctor deems it necessary.
2. What you need to know before taking Ciprobay
Do not take Ciprobay:
If you are allergic to the active substance, to other quinolone drugs or to any other ingredients of this medicine (listed in section 6);
If you are taking tizanidine (see section 2: Other drugs and Ciprobay).
Warnings and Precautions
Talk to your doctor before taking Ciprobay:
If you have ever had kidney problems because your treatment may need to be adjusted;
If you suffer from epilepsy or other neurological diseases;
If you have a history of tendon problems during previous treatment with antibiotics such as Ciprobay;
If you are diabetic, because you may be at risk of hypoglycemia after taking ciprofloxacin;
If you have myasthenia gravis (a type of muscle weakness) because symptoms may be exacerbated;
If you have heart problems. Caution should be exercised in the use of Ciprobay if you were born with or have a family history of QT prolongation (see ECG, electrical recording of the heart), have salt imbalance in the blood (especially low levels of potassium or magnesium in the blood), you a very slow heart beat (called "bradycardia") have a weak heart (heart failure) have a history of heart attack (myocardial infarction) if you are female or you are elderly or are taking other medicines that cause abnormal ECG changes (see Other drugs and Ciprobay);
If you know that you or a member of your family has a deficiency of glucose-6-phosphate dehydrogenase (G6PD), since you may be at risk of anemia after taking ciprofloxacin.
For the treatment of certain infections of the genital tract, your doctor may prescribe another antibiotic in addition to ciprofloxacin. If there is no improvement in symptoms after 3 days of treatment, please consult your doctor.
While taking Ciprobay
Tell your doctor immediately if you experience any of these symptoms while taking Ciprobay. Your doctor will decide whether treatment with Ciprobay should be discontinued.
Severe, sudden allergic reaction (anaphylactic reaction / shock, angioedema). Even with the first dose is a small chance that you may develop a severe allergic reaction with the following symptoms: chest tightness, feeling dizzy, fainting or dizziness or fainting when standing up. If this happens, stop taking Ciprobay and tell your doctor immediately;
Pain and swelling in the joints and inflammation of the tendon can sometimes occur, especially if you are elderly and are also treated with corticosteroids. Inflammation and rupture of the tendon can occur even within 48 hours of the start of treatment or within a few months after cessation of treatment with Ciprobay. At the first sign of pain or inflammation, stop taking Ciprobay and let rest the painful area. Avoid unnecessary stress because it may increase the risk of tendon rupture;
If you suffer from epilepsy or other neurological disorders such as cerebral ischemia or stroke, you may experience side effects associated with the central nervous system. If this happens, stop taking Ciprobay and tell your doctor immediately;
The first time you are taking Ciprobay, it is possible to obtain psychiatric reactions. If you suffer from depression or psychosis, it is possible that your symptoms get worse during treatment with Ciprobay. In rare cases, depression or psychosis can progress to suicidal thoughts, suicide attempts or suicide. If this happens, stop taking Ciprobay and tell your doctor immediately;
May experience symptoms of neuropathy, such as pain, burning, tingling, numbness and / or weakness. If this happens, stop taking Ciprobay and tell your doctor immediately;
Reported hypoglycemia, the most common in diabetic patients, especially the elderly. If this happens, contact your doctor immediately;
You may develop diarrhea while taking antibiotics, including Ciprobay, or even several weeks after you stop taking them. If it becomes severe or persistent or you notice that your stool contains blood or mucus, stop taking Ciprobay, because this condition can be life threatening. Do not take medicines that stop or slow down bowel movements and contact your doctor;
Tell the doctor or laboratory staff that you are taking Ciprobay if you take samples of blood or urine;
If you suffer from kidney problems, talk to your doctor as you may need your dosage to be adjusted;
Ciprobay may cause liver damage. If you notice symptoms such as loss of appetite, jaundice (yellowing skin extraction), dark urine, itching or tenderness of the stomach, stop taking Ciprobay and call your doctor immediately;
Ciprobay may cause a decrease in white blood cells and your resistance to infection may be decreased. If you have an infection with symptoms such as fever and serious deterioration of your general condition, or fever with local infection symptoms such as sore throat / pharynx / mouth or urinary problems, you should see your doctor. A blood test will check possible reduction of white blood cells (agranulocytosis). It is important to inform your doctor of medicine;
When taking Ciprobay, your skin becomes more sensitive to sunlight or ultraviolet (UV) rays. Avoid exposure to strong sunlight or artificial sources of UV light such as tanning beds.
Ciprobay and other drugs
Please tell your doctor or pharmacist if you are taking, have recently taken or take any other medicines.
Do not take Ciprobay with tizanidine, because this may lead to side effects such as low blood pressure and sleepiness (see "Do not take Ciprobay").
It is known that these drugs interact with Ciprobay in your body. If you are taking Ciprobay concomitantly with these drugs, it is possible to change their therapeutic effects. It may also increase the likelihood of experiencing side effects.
Tell your doctor if you take:
Vitamin K antagonists (eg. warfarin, acenocoumarol, phenprocoumon or fluindione) or other oral anticoagulants (blood thinners);
methotrexate (for certain types of cancer, psoriasis, rheumatoid arthritis);
theophylline (for breathing problems);
tizanidine (for muscle spasticity in multiple sclerosis);
clozapine (an antipsychotic);
ropinirole (for Parkinson's disease);
phenytoin (for epilepsy);
metoclopramide (for nausea and vomiting);
cyclosporine (for skin conditions, rheumatoid arthritis, or for organ transplantation);
other medicines that can change your heartbeat; drugs, which belong to the group of antiarrhythmic agents (e. quinidine, hydroquinidine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide), tricyclic antidepressants, some antimicrobial agents (belonging to the macrolide), some antipsychotics.
Ciprobay may increase the levels of these medicines in your blood:
pentoxifylline (for circulatory disorders);
duloxetine (depression, diabetic nerve or incontinence);
lidocaine (for heart conditions or anesthetic use);
sildenafil (e. for erectile dysfunction).
Some drugs reduce the effect of Ciprobay.
Tell your doctor if you take or want to take:
phosphate-binding polymer (eg. sevelamer or lanthanum carbonate);
medications or supplements containing calcium, magnesium, aluminum or iron.
If these products are important to you, take Ciprobay about 2 hours before or no sooner than four hours after them.
Ciprobay with food and drink
If you are taking Ciprobay during regular meals, do not eat or drink any dairy products (like milk or yogurt) or drinks with added calcium when taking the tablets because they can affect the absorption of the active ingredient.
Pregnancy and lactation
If you are pregnant or breast-feeding, you may be pregnant or planning to have a baby, ask your doctor or pharmacist before taking this medicine.
It is preferable to avoid the use of Ciprobay during pregnancy.
Do not take Ciprobay during breast-feeding because ciprofloxacin is excreted in breast milk and may harm your baby.
Driving and using machines
Ciprobay can reduce your attention. Some neurological side effects may occur. So check how you react to Ciprobay before driving a vehicle or operating machinery. If in doubt, consult your doctor.
3. How to take Ciprobay
Your doctor will tell you how much Ciprobay should take, how often and for how long. This will depend on the type of infection and the weight of it.
Tell your doctor if you have kidney problems, because they may require dose adjustment.
Treatment usually lasts 5 to 21 days but may be longer in severe infections. Always take this medicine exactly as your doctor has told. If you are not sure how many tablets to take and how to take Ciprobay, ask your doctor or pharmacist.
a. Swallow the tablets with plenty of fluid. Do not chew them because their taste is not pleasant.
b. Try to take the tablets at about the same time each day.
in. You can take the tablets with regular intake of food or another. Calcium, which is a normal part of the diet will not seriously affect their adoption. Do not take the tablets Ciprobay with dairy products such as milk or yoghurt or with fortified fruit juices (eg. Calcium fortified orange juice).
Remember to drink plenty of fluids when taking this medicine.
If you take more dose Ciprobay
If you take more than your prescribed dose, seek medical attention immediately. If possible, take your tablets or their packaging with you to show the doctor.
If you forget to take Ciprobay
Take the normal dose as soon as possible and then continue on the prescribed schedule. However, if it is almost time to become next dose, skip the missed dose and continue with the scheme. Do not take a double dose to make up for a missed dose. Be sure to complete the entire course of treatment.
If you stop taking Ciprobay
It is important to complete the course of treatment, even if after a few days already feel better. If you stop taking the medicine too soon, your infection is possible to not be completely cured and the symptoms reappear or worsen. It is possible to develop resistance to the antibiotic.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Common: may affect up to 1 in 10 people:
joint pain in children.
Uncommon: may affect up to 1 in 100 people:
fungal infections super;
high levels of eosinophils (a type of white blood cell);
hyperactivity or agitation;
headache, dizziness, sleep problems or disorders of taste sensations;
vomiting, stomach pain, digestive problems such as stomach upset (indigestion / heartburn) or intestinal gas;
increased levels of certain substances in the blood (transaminases and / or bilirubin);
rash, itching or hives;
joint pain in adults;
impaired renal function;
pain in the muscles and bones, malaise (asthenia) or fever;
increases in alkaline phosphatase in the blood (the substance in the blood).
Rare: may affect up to 1 in 1,000 people:
inflammation of the colon (colitis) associated with the use of antibiotics (in very rare cases can be fatal) (see section 2: Warnings and Precautions);
changes in blood count (leukopenia, leukocytosis, neutropenia, anemia), increased or decreased amount of clotting factor (thrombocytes);
allergic reactions, swelling (edema) or rapid swelling of the skin and mucosa (angioedema);
high blood sugar (hyperglycemia);
low blood sugar (hypoglycemia) (see section 2. Warnings and Precautions);
confusion, disorientation, anxiety reactions, abnormal dreams, depression (potentially leading to thoughts of suicide, suicide attempts or suicide) or hallucinations;
pins and needles, unusual sensitivity to sensory stimuli, decreased skin sensitivity, tremors, convulsions (see section 2: Warnings and precautions) or dizziness;
vision problems, including. double vision;
tinnitus, hearing loss, hearing impairment;
increased heart rate (tachycardia);
dilation of blood vessels (vasodilation), low blood pressure, or seizures;
breathlessness, including asthma symptoms;
liver disorders, jaundice (cholestatic jaundice) or hepatitis;
sensitivity to light (see section 2: Warnings and Precautions);
muscle pain, joint inflammation, increased muscle tone or cramps;
renal failure, blood or crystals in the urine (see section 2: Warnings and precautions), inflammation of the urinary tract;
fluid retention or excessive sweating;
Increased levels of the enzyme amylase.
Very rare: may affect up to 1 in 10,000 people:
a certain type of reduction in the number of red blood cells (hemolytic anemia); dangerous decrease in the number of one type of white blood cells (agranulocytosis); decrease in the number of red and white blood cells and platelets (pancytopenia), which can be fatal; and bone marrow depression, which can also be fatal (see section 2: Warnings and Precautions);
severe allergic reactions (anaphylactic reaction or anaphylactic shock, which can be fatal - serum sickness) (see section 2: Warnings and Precautions);
mental disorders (psychotic reactions, potentially leading to thoughts of suicide, suicide attempts or suicide) (see section 2: Warnings and Precautions);
migraine, disturbed coordination, unsteady walk (gait disturbance), disorder of sense of smell (olfactory disorders), increased pressure in the brain (intracranial pressure and cerebral pseudotumor);
changes in the perception of colors;
inflammation of the wall of blood vessels (vasculitis);
death of liver cells (liver necrosis) very rarely can lead to life-threatening liver failure;
small pinpoint hemorrhages under the skin (petechiae) various skin rashes (eg, potentially fatal Stevens-Johnson and toxic epidermal necrolysis);
muscle weakness, inflammation of the tendons, tendon rupture - especially of the large tendon in the back of the ankle (Achilles tendon) (see section 2: Warnings and Precautions); worsening of symptoms of myasthenia gravis (see section 2: Warnings and precautions).
Not known: frequency can not be estimated from available data:
problems related to the nervous system, pain, burning, tingling, numbness and / or weakness in the extremities (peripheral neuropathy and polyneuropathy);