Carvedil. 25 mg 28 tablets

Carvedil. 25 mg 28 tablets
€ 14.00
Add to Cart
Disease of the arteries supplying blood to the heart (chronic - And adjunctive therapy secondary to severe chronic heart failure (II- IV functional class classification NYHA).

Carvedil. 25 mg 28 tablets

 
 
Carvedil 25 mg is used:
- For the treatment of high blood pressure without the clarified cause (essential hypertension)
- A disease of the arteries supplying blood to the heart (chronic - And adjunctive therapy secondary to severe chronic heart failure (II- IV functional class classification NYHA).
 
2 What you should consider before taking Carvedil 12.5 mg?
2.1 Do not take Carvedil 12.5 mg:
- If you suffer from severe heart failure requiring treatment with intravenous medications that increase the force of contraction of the heart muscle (NYHA class IV heart failure requiring parenteral inotropic therapy)
- If you suffer from respiratory disease characterized by narrowing of bronchi (chronic obstructive pulmonary disease associated "with bronchial obstruction)
- If you suffer from severe impairment of liver function
- If you suffer from asthma
- If you suffer from disorders of impulse conduction from the atria to the chambers of the heart (second and third degree AV block)
- If your heart rate at rest is below 50 beats per minute (severe bradycardia)
- If you suffer from any sinus node disease (sick sinus syndrome assembly including sino-atrial block)
- If you are in the cardio-vascular shock
- If your blood pressure is very low (systolic blood pressure below 85 mmHg)
- If you suffer from Prinzmetal variant angina (a rare form of angina)
- If you suffer from untreated hormone-dependent tumor of the adrenal medulla (pheochromocytoma)
- If you are allergic to carvedilol or any of the excipients
- If your blood is very acidic pH (metabolic acidosis)
- If you suffer from severe narrowing artery disease and toes
- If you are currently treated with intravenous verapamil or diltiazem.
 
2.2 Special warnings when taking Carvedil 12.5 mg:
Special precautions which must be taken into account, especially in patients with cardiac failure
In patients with chronic heart failure, Carvedil 12.5 mg may be used as adjunctive therapy to the existing therapy with other drugs (ACE inhibitors, digitalis, and / or vasodilators). Therapy should be initiated in hospital and monitored by a doctor. Treatment should not be initiated before the patient is stabilized with other drugs for at least 4 weeks.
Patients with severe heart failure, shortage of water and salts, geriatric patients and patients with low blood pressure should be monitored for at least two hours after the first dose Carvedil 25 mg or increasing the dose due to the possibility of a sharp drop in blood pressure. Please discuss this with your doctor.
Symptoms of heart failure may worsen at the beginning of treatment or when increasing the dose of Carvedil 25 mg. If this happens, your doctor may increase the dose of diuretic (water tablets). However, it is sometimes necessary to reduce the dose or stopping Carvedil 25 mg. Your doctor will increase the dose of Carvedil, until symptoms of heart failure or symptoms of low blood pressure is not controlled.
Patients with heart failure, hypotension (systolic blood pressure less than 100 mmHg) may experience a temporary worsening of renal function during treatment Carvedil 25 mg. This is especially true for patients with additional diseases, such as coronary heart disease, atherosclerosis and / or existing depressed renal function. Renal function should be carefully monitored in these patients during the adjustment of the dose of Carvedil 25. If renal function deteriorates significantly, the dose of carvedilol should be reduced or treatment stopped.
Carvedil 25 mg should be used with caution in patients with chronic heart failure treated with digitalis as digitalis and Carvedil may extend conduction time of the pulses from the upper to the lower chambers of the heart.
 
Other warnings Carvedil 25 mg in general beta-blockers:
Patients with diseases of the respiratory tract, and a tendency to bronchospasm (chronic obstructive pulmonary disease), needs to be carefully monitored at the beginning of therapy and during the adjustment of the dose. Carvedil dose of 25 mg should be reduced if you have symptoms of bronchospasm. Discuss with your doctor if you suffer from bronchial illness.
Patients with diabetes mellitus (diabetes) must regularly monitor the level of blood glucose and if necessary to adjust the dose of a drug to reduce blood sugar, while on therapy with Carvedil 25 mg and particularly a change in dosage. Blood glucose should be measured during prolonged starvation.
Carvedil can mask or suppress the symptoms associated with overactivity of the thyroid gland.
Carvedil can cause a slow heart rate (bradycardia). If your heart rate is below 55 beats per minute, your doctor may reduce the dose of Carvedil 25 mg.
Concomitant use of Carvedil 25 mg of calcium channel blockers of the verapamil and diltiazem (medicines to reduce blood pressure) or other medicines used to treat irregular heart rhythm (antiarrhythmics), especially amiodarone requires careful monitoring of blood pressure and ECG. Simultaneous intravenous administration of these drugs should be avoided.
Attention should be paid when Carvedil used together with cimetidine (a medicine inhibit the production of hydrochloric acid), because it may increase the effects of Carvedil 25 mg.
People using contact lenses should consider the possibility of reduced lacrimation (tear reduced).
Patients with a history of severe hypersensitivity reactions and patients undergoing allergen specific immunotherapy (hiposensitivna therapy) may experience worsening of allergic (anaphylactic) reactions.
Patients with psoriasis should use Carvedil 25 mg with caution because of the possibility of worsening symptoms of skin disease.
Carvedil 25 mg should be used with caution in patients with peripheral vascular disease (eg Raynaud's phenomenon) as the beta-blockers such as carvedilol may worsen the symptoms of the disease.
If you know that you are slow metabolisers of debrisoquine, you should be closely monitored especially in early treatment. Because there is not enough clinical experience, Carvedil 25 mg should not be used in patients with high blood pressure (secondary hypertension or unstable), drop in blood pressure upon standing (orthostatic hypotension), acute inflammatory disease of the heart (with hemodynamic disorder) narrowing of the heart valves, severe arterial vascular disease of the legs or simultaneous use of alpha-1 blocker or alpha-2 blocker.
In patients with tumor adrenal medulla (pheochromocytoma), alpha-blocker medication should be initiated prior to initiation of therapy with carvedilol. Should be carefully monitored these patients when taking Carvedil 25 mg.
Carvedil 25 mg should be used with caution in patients with impaired impulse conduction from the atria to the cameras (first degree AV block).
Attention should be paid to both the use of certain anesthetics, due to an increased risk of a drop in blood pressure.
Like other beta-blockers, Carvedil 25 mg should not be stopped suddenly. This is especially true for patients with coronary heart disease. Therapy Carvedil 25 mg should be discontinued gradually over a period of 2 weeks, the dose was reduced by half an interval of three days. Discuss this with your doctor.
a) Children
The safety and efficacy have not been established in children and adolescents under 18 years of age. Carvedil 25 mg should be used in this group of patients.
b) Geriatrics
Geriatric patients may be more sensitive to the effects of Carvedil 25 mg and should be carefully monitored.
c) Pregnancy
Carvedil should be used during pregnancy only after careful assessment of the benefit / risk ratio.
Beta-blockers reduce placental perfusion, which can lead to intra-uterine fetal death and stillbirth. In addition, can be adverse effects on the fetus and newborn (especially low blood sugar - hypoglycemia and slow heart rate -bradikardiya). There is an increased risk of cardiac and respiratory complications in the newborn period slednatalniya. Treatment should be stopped 2-3 days before the expected birth, but if this is not possible, the infant should be monitored during the first 2-3 days of life.
d) Breastfeeding
Carvedil accumulates in breast milk, even in larger concentrations than in maternal blood. Therefore should not breast-feed during treatment with Carvedil 25 mg.
e) Effects on ability to drive and use machines
Use of this medication requires regular medical examinations. There are different individual reactions that reduce the ability of active attention and quick reactions required for driving, operating machinery or unsafe work. This is especially true at the start of treatment when increasing the dose, add new medication or if it is used simultaneously with alcohol.
f) Important information about some of the ingredients Carvedil 25 mg
This medicine contains lactose and sucrose. If you know you have an intolerance to lactose and sucrose should not take Carvedil 25 mg before you consult with your doctor.
 
2.3 Interactions with other drugs
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, even those not prescribed by a doctor.
Interactions with medicines to treat abnormal heart rhythm (antiarrhythmics)
Co-administration of 25 mg Carvedil with calcium channel blockers (such as verapamil, diltiazem), amiodarone or class I antiarrhythmic drugs requires careful monitoring of blood pressure and ECG. There are cases of a slow heart rate (bradycardia), cardiac arrest and ventricular fibrillation, soon after beta-blocker therapy in patients receiving concomitant amiodarone. Concomitant use of Class IV 1a or 1c antiarrhythmics, class is associated with increased risk of heart failure.
Concomitant therapy with 25 mg of Carvedil drugs reduce blood pressure reserpine, guanethidine, methyldopa, guanfacine and monoamine oxidase inhibitors (except MAO-B inhibitors) may lead to further delays in heart rate. Your doctor should closely monitor your cardio-vascular function.
Some drugs that reduce high blood pressure (dihydropyridines, such as nifedipine)
Co-administration of dihydropyridines and Carvedil 25 mg requires careful monitoring because there are cases of heart failure and severe hypotension.
Drugs expanding coronary arteries (nitrates)
These drugs and Carvedil 25 mg mutually reinforcing effects of reducing blood pressure.
Cardiac glycosides, medicines to treat heart failure (digoxin and digitoxin)
Concomitant use with Carvedil 25 mg may enhance the effects of cardiac glycosides. Blood levels of glycoside should be measured prior to initiation of therapy, a change in the dose or discontinuation of therapy Carvedil 25 mg.
Other medicines to lower blood pressure
Carvedil 25 mg may enhance the effects of other drugs for lowering blood pressure (such as alpha-1 receptor antagonists) and drugs whose side effect is a decrease in blood pressure (barbiturates, phenothiazines, tricyclic antidepressants, vasodilators).
Drugs suppress the immune response
Concomitant use of cyclosporine and Carvedil 25 mg may cause elevated blood levels of cyclosporine.
Drugs to reduce blood sugar (antidiabetic agents, including insulin)
Carvedil 25 mg may enhance the reduction of blood sugar. Symptoms of low blood sugar (hypoglycemia) can be masked. Patients with diabetes need to regularly check your blood sugar levels.
clonidine
In case of discontinuation of clonidine and Carvedil, Carvedil 25 mg should be stopped several days before starting the gradual withdrawal of clonidine.
Anesthetics (inhalational anesthetics)
Anaesthetic agents may enhance the reduction of blood pressure by 25 mg of Carvedil during anesthesia. Please tell the anesthetist that you are taking Carvedil 25 mg.
Drugs for the treatment of rheumatic diseases and pain (NSAIDs), corticosteroids and estrogens
The antihypertensive effect of Carvedil 25 mg reduced due to retention of water and sodium (side effect of these drugs).
Drugs are metabolized by the same enzyme systems in the liver (cytochrome P450)
The following medicines may influence the effects of Carvedil 25 mg: rifampicin (antibiotic), barbiturates (to help you sleep medicines), cimetidine (a medicine inhibit the production of hydrochloric acid), ketoconazole (medicine for fungal infections), fluoxetine (an antidepressant), haloperidol (an antipsychotic) , verapamil (a medicine to treat abnormal heart rhythms), erythromycin (an antibiotic). Patients taking any of these medicines together with Carvedil 25 mg should be carefully monitored.
sympathomimetic
When these drugs are used concomitantly with carvedilol, an increased risk of high blood pressure and slow heart rate (severe bradycardia).
Antimigraine drugs (ergotamine)
When these drugs are used concomitantly with carvedilol, the risk of a rise in blood pressure due to narrowing of the blood vessels.
muscle relaxants
Carvedil 25 mg increased muscle-relaxing effect.
 
2.4 When Carvedil 25 mg was administered with food or drink
Alcohol: Carvedil 25 mg may increase the effects of alcohol.
 
3 How to take Carvedil 25 mg?
Always take Carvedil 25 mg as just follow the instructions of your doctor. Counsel with your doctor or pharmacist if anything you do not understand.
3.1 Method of administration
For oral use
The tablets should be taken with sufficient voda.Ne need to take the tablets with food.
Patients with heart failure, however, should not take Carvedil 25 mg with food to slow absorption, thereby reducing the risk of a sharp drop in blood pressure upon standing (orthostatic hypotension).
There tablets Carvedil other doses which are not covered by Carvedil 25 mg.
 
3.2 If your doctor has prescribed another dose to treat high blood pressure without a specific cause (essential hypertension) is:
For the treatment of hypertension, Carvedil 25 mg may be used alone or in combination with other blood pressure lowering drugs, and especially water tablets (thiazide diuretics).
Recommended once-daily dosing; maximum single dose is 25 mg and the maximum daily dose - 50 mg.
  adults
The recommended starting dose is half a tablet Carvedil 25 mg (equivalent to 12.5 mg carvedilol) once daily for the first 2 days.
Treatment can then continue with 1 tablet Carvedil 25 mg (equivalent to 25 mg carvedilol) once daily. If necessary, the dose may be escalated gradually in the range of not less than 2 weeks.
Elderly
The recommended starting dose for the treatment of hypertension is half Carvedil tablet 25 mg (equivalent to 12.5 mg carvedilol) once daily. This dose may suffice for long-term therapy.
If this dose does not achieve adequate control of blood pressure, it is necessary to gradually increase the dosage in the range of not less than 2 weeks.
To treat diseases pa pa arteries supplying blood to the heart (chronic angina): Recommended dosage 2 times a day.
adults
The recommended starting dose for the treatment of hypertension is half tablet Carvedil 25 mg (equivalent to 12.5 mg carvedilol) 2 times daily for the first 2 days. Then treatment should continue with 1 tablet Carvedil 25 mg (equivalent to 25 mg carvedilol) two times a day. If necessary, the dose may be escalated gradually in an interval of at least 2 weeks up to a maximum recommended daily dose of 100 mg, divided into 2 daily administration.
Elderly
The recommended starting dose is Vi tablet Carvedil 25 mg (equivalent to 12.5 mg carvedilol) 2 times daily for the first 2 days. Then treatment can be continued with the recommended maximum dose of 1 tablet Carvedil 25 mg (equivalent to 25 mg carvedilol) two times a day.
As adjunctive therapy for the treatment of moderate to severe chronic heart failure:
For the treatment of moderate to severe chronic heart failure, Carvedil 25 mg was used as an add-on to standard therapy of other blood pressure lowering drugs (ACE inhibitors, digitalis, and / or vasodilators).
 
 
€ 14.00
Add to Cart
Close