COSTI 10 mg. 30 tablets

COSTI 10 mg. 30 tablets
€ 15.00
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What COSTI and what it is used
The name of your medicine is COSTI, and its active substance is domperidone, which belongs to the group of medicines known as "dopamine agonists".
They can increase the rate at which food passes through the gut in conditions under which it takes longer than necessary.
This medicine is used in adults and children to treat nausea (feeling sick) and vomiting.

2. What you need to know before taking COSTI
Do not take COSTI
if you are allergic to domperidone or any of the other ingredients of this medicine (listed in section 6). Allergic reaction may occur to many drugs and can be recognized as a rash, itching, swelling of face or lips or shortness of breath;
if your doctor has told you that you have a serious intestinal problem such as internal bleeding, obstruction or perforation;
if you suffer from a disease of the pituitary gland, known as prolactinoma;
if you have moderate or severe liver disease;
if your ECG (electrocardiogram), shows a heart problem called "QT prolongation"
if you have or have had a problem where your heart can not pump blood to all parts of the body as it should (a condition called heart failure);
if you have a disease, with the result that the amount of potassium or magnesium in your blood are low, or potassium level is high;
if you are taking certain medicines (see. "Other medicines and Bones").
You should not use bones if you have severe stomach cramps (shrinking stomach pain) or persistent bowel movements. If you feel something, consult your doctor before starting treatment with bones.

Warnings and Precautions
Talk to your doctor before taking this medicine if:
have liver disease (hepatic dysfunction or failure) (see. "Do not take Bones");
have kidney disease (renal dysfunction or failure);
It is advisable to seek advice from your doctor in case of prolonged treatment, as may be necessary to take a lower dose or to use it less often, and your doctor may want to carry out regular reviews.
Apply domperidone in children or elderly patients (increased risk of extrapyramidal effects such as abnormal eye movement, distortion neck, tremors and muscle stiffness.
Domperidone may be associated with an increased risk of abnormal heart rhythms and cardiac arrest. The risk may be higher in patients older than 60 years, or at daily doses higher than 30 mg. The risk is also increased when domperidone are administered together with certain drugs. Tell your doctor or pharmacist if you are taking medicines to treat infections (fungal or bacterial infection) and / or if you suffer from heart problems or HIV / AIDS (see. "Other medicines and Bones").
Domperidone should be administered at the lowest effective dose for adults and children.
Contact your doctor if you experience an abnormal heart rhythm, such as palpitations, difficulty breathing, loss of consciousness while taking domperidone. Treatment with domperidone should be discontinued.

Other medicines and COSTI
Tell your doctor or pharmacist if you are taking, you have recently taken or might take any other medicines.

COSTI do not take if you use medicines to treat:
fungal infections such as azole antifungal agents, particularly ketoconazole, fluconazole or voriconazole, taken orally;
bacterial infections, particularly erythromycin, clarithromycin, telithromycin, moxifloxacin (that is, antibiotics);
heart problems or high blood pressure (eg. amiodarone, dronedarone, quinidine, disopyramide, dofetilide, sotalol, diltiazem, verapamil);
psychosis (eg. haloperidol, pimozide, sertindole);
depression (eg. citalopram, escitalopram);
gastrointestinal disorders (eg. cisapride, dolasetron, prucalopride);
allergy (e. mequitazine, mizolastine);
malaria (especially halofantrine);
AIDS / HIV (protease inhibitors);
Cancer (e. Toremifene mandetanib, vincamine).
Tell your doctor or pharmacist if you are taking to treat the infection, heart problems or HIV / AIDS.
It is important to ask your doctor or pharmacist if Bones is safe for you if you are taking other medicines, including medicines obtained without a prescription.

Pregnancy and lactation
If you are pregnant or breast-feeding, you think you may be pregnant or planning to become pregnant, ask your doctor or pharmacist before taking this medicine.

The drug should not be used during pregnancy unless it is considered that the benefit outweighs the potential risk to the fetus.

The aft found small amounts of domperidone. Domperidone can cause side effects affecting the heart of the infant. Domperidone should not be used during lactation only if your doctor considers it absolutely necessary.
Ask your doctor before taking this medicine.

Driving and using machines
Driving or operating machinery should not be a problem as Bones is a medicine that usually does not lead to loss of attention. However, before driving or operating machinery should you know how you are affected by the drug.

3. How to take Bones
Always take this medicine exactly as you have been told by your doctor. If you're not sure, ask your doctor or pharmacist.
Recommended Bones taken orally before meals. Assuming after eating somewhat slows its absorption.
Follow these instructions unless your doctor has told

Adults and adolescents 12 years and older and weighing 35 kg or more
The usual dose is one tablet administered 3 times daily, if possible before eating.
Do not take more than 3 tablets a day.

Duration of treatment
Symptoms usually subside after 3-4 days the medicine. Bones do not take more than 7 days without consulting your doctor.

Important: do not exceed the recommended dose.

If you take more dose COSTI
If you use or take more dose COSTI , immediately contact your doctor, pharmacist or poison center, especially if a child has taken more than the recommended dose. In case of overdose can be symptomatic treatment. It can be done ECG monitoring because of the possibility of a heart problem called "prolonged QT interval".

If you forget to take COSTI
Take your medicine as soon as possible. If it is almost time for your next dose, wait until the time comes for it and continue with your regular schedule. Do not take a double dose to make up the missed dose.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Domperidone is well tolerated, and most patients do not exhibit any side effects.

If you experience any of these, stop taking the drug and seek immediate medical attention:
Not known (frequency can not be established from the available data):
Seizures or convulsions;
Involuntary movements of the face or hands and feet, excessive shaking;
Excessive muscle stiffness or muscle spasms;
Allergic reactions: signs of allergy include rash (such as hives), itching, shortness of breath, wheezing and / or swelling of the face or neck, flushing or fainting;
Disorders of the cardiovascular system: reports of abnormal heart rhythm (rapid or irregular heartbeat); if this happens, you should immediately stop treatment. Domperidone may be associated with an increased risk of abnormal heart rhythms and cardiac arrest. The risk may be higher in patients older than 60 years, or at daily doses higher than 30 mg. Children and adults should be administered at the lowest effective dose of domperidone.
If you experience any of these, stop taking the drug and contact your doctor:
Common (may affect more than 1 in 10 people):
Dry mouth.
Uncommon (may affect up to 1 in 100 people):
Loss of sexual interest or decreased sexual interest;
Drowsiness or headaches;
Pain or pressure in the chest, or discharge from the breasts;
General feeling of weakness.
Other side effects that may occur
Not known (frequency can not be established from the available data):
Agitation or nervousness;
Impaired eye movement;
Inability to urinate;
Swelling of the breasts (even in men);
Cessation of menstrual cycle;
Changes in the results of some laboratory tests. If you do liver function tests, tell your doctor or nurse that you are taking COSTI

5. How to store COSTI
Keep at temperatures below 25 ° C, away from light and dry. Keep tablets in the original package.
Keep out of reach of children.
Do not use this medicine after the expiry date stated on the carton and blister each tablet. The expiry date refers to the last day of that month.
Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer use. These measures will help to protect the environment.

6. Contents of the pack and further information
The active substance is domperidone. Each tablet contains 10 mg of COSTI domperidone.
Other ingredients are: corn starch, microcrystalline cellulose, sodium starch glycolate, croscarmellose sodium, colloidal silica, magnesium stearate, sodium erythrosine.

COSTI looks like and contents of the pack
COSTI tablet is 10 mg pink, round, flat scored tablet marked "MS" and has a diameter of 7 mm.
The tablets are packaged in PVC-Al foil of ten tablets in a cardboard box with information about the patient.
Packs of 20 and 30 tablets.
Not all pack sizes may be marketed.
€ 15.00
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