CIPROLON 750 mg. 10 tablets
CIPROLON is an antibiotic of the fluoroquinolone. The active substance is ciprofloxacin. Ciprofloxacin works by killing the bacteria that caused the infection. Only works on certain types of bacteria.
CIPROLON used in adults to treat the following bacterial infections:
• respiratory tract infections
• prolonged or repeated ear infections or sinus
• infection of the testicles
• infections of the genitals in women
• infections of the gastrointestinal tract, and abdominal infections
• infections of skin and soft tissue
• infections of the bones and joints
• for the treatment of infections in patients with very low blood leukocytes (severe neutropenia)
• to prevent infections in patients with a very low number of leukocytes in the blood (severe neutropenia)
• prevention of infection with Neisseria meningitidis
• inhalation of anthrax spores
If you suffer from severe infection or one caused by more than one type of bacteria, you may be given additional antibiotic treatment than CIPROLON.
Children and adolescents
CIPROLON be used in children and adolescents under specialist medical supervision for the treatment of the following bacterial infections:
• acute respiratory infections in children and adolescents suffering from cystic fibrosis
• complicated urinary tract infections, including infections that have reached the kidneys (pyelonephritis)
• inhalation of anthrax spores
CIPROLON can also be used to treat other specific severe infections in children and adolescents when your doctor considered this necessary.
2. BEFORE YOU TAKE CIPROLON
CIPROLON not take if you are:
• are allergic (hypersensitive) to CIPROLON or other quinolone drugs or any of the other ingredients of the tablets for CIPROLON (see. Section 6)
• taking tizanidine (see point Taking other medicines)
Take special care with CIPROLON
Tell your doctor if:
• have ever had kidney problems because your treatment should be adjusted
• suffer from epilepsy or other neurological disorders
• have a history of tendon problems during previous treatment with antibiotics such as CIPROLON
• have myasthenia gravis (a type of muscle weakness)
• have a history of abnormal heartbeat (arrhythmia)
While taking CIPROLON
Tell your doctor immediately if you experience any of the following symptoms while taking CIPROLON. Your doctor will decide whether treatment with CIPROLON should be discontinued.
• Severe, sudden allergic reaction (anaphylactic reaction / shock). Even with the first dose is a small chance that you may develop a severe allergic reaction with the following symptoms: chest tightness, feeling dizzy, sick or faint or get dizzy when standing up. If you have this happens, stop taking CIPROLON and immediately contact your doctor.
• Pain and swelling in the joints and tendinitis may occur occasionally, particularly if you are elderly and you are treated with corticosteroids. At the first sign of pain or inflammation, stop taking CIPROLON and let rest the painful area. Avoid unnecessary stress because it may increase the risk of tendon rupture.
• If you suffer from epilepsy or other neurological disorders such as cerebral ischemia or stroke, it is possible to obtain effects associated with the central nervous system.
• The first time you take CIPROLON possible to get psychiatric reactions. If you suffer from depression or psychosis, it is possible that your symptoms get worse during treatment with CIPROLON.
• You may develop diarrhea while taking antibiotics
including CIPROLON or even several weeks after you stop taking them. If it becomes severe or persistent or you notice that your stool contains blood or mucus, stop taking CIPROLON because this condition can be life threatening. Do not take medicines that stop or slow down bowel movements and contact your doctor.
• Tell the doctor or laboratory acceptance CIPROLON if you take samples of blood or urine.
• CIPROLON can cause liver damage. If you notice symptoms such as loss of appetite, jaundice (yellowish skin extraction hue), dark urine, itching or tenderness of the stomach, stop taking CIPROLON and contact your doctor immediately.
• Ciprofloxacin can reduce the number of white blood cells and your resistance to infection may be decreased. If you have an infection with symptoms such as fever and serious deterioration of your general condition, or fever with local infection symptoms such as sore necked / pharynx / mouth or urinary problems you should immediately see your doctor. A blood test will check possible reduction of white blood cells (agranulocytosis). It is important to inform your doctor of medicine.
• Tell your doctor if your family member has a deficiency of glucose-6-phosphate dehydrogenase (O6RS) as you may have a risk of anemia with ciprofloxacin.
• When taking CIPROLON your skin becomes more sensitive to sunlight and UV rays. Avoid exposure to strong sunlight or artificial sources of UV light such as tanning beds.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Do not take CIPROLON with tizanidine, because this may lead to side effects such as low blood pressure and sleepiness (see. "Do not take CIPROLON").
It is known that these drugs interact with CIPROLON in your body. If you take CIPROLON simultaneously with these medicines can influence the therapeutic effects. Also, it can increase the likelihood of experiencing side effects.
Tell your doctor if you take:
• warfarin or other anticoagulants (blood thinners)
• probenecid (for gout)
• methotrexate (for certain types of cancer, psoriasis, rheumatoid arthritis)
• theophylline (for breathing problems)
• tizanidine (for muscle spasms in multiple sclerosis)
• clozapine (an antipsychotic)
• ropinirole (for Parkinson's disease)
• phenytoin (for epilepsy)
CIPROLON can raise the levels of these medicines in your blood:
• pentoxifylline (for circulatory disorders)
Some drugs reduce the effect of CIPROLON.
Tell your doctor if you take or want to take:
• mineral supplements
• phosphate-binding polymer (eg., Sevelamer)
• medicines or supplements containing calcium, magnesium, aluminum or iron If these products are important to you, take CIPROLON about 2 hours before or no sooner than four hours after them.
Taking CIPROLON with food and drink
If you take CIPROLON during regular meals, do not eat or drink any dairy products (like milk or yogurt) or drinks with added calcium when taking the tablets because they can affect the absorption of the active ingredient.
Pregnancy and lactation
It is preferable to avoid the use of CIPROLON pregnancies. Tell your doctor if you plan to become pregnant. Do not take CIPROLON during breast-feeding because ciprofloxacin is excreted in breast milk and may harm your baby.
Driving and using machines
CIPROLON can reduce your attention. Some neurological side effects may occur. So check how you react to CIPROLON lredi to drive vehicles or operate machinery. If in doubt, consult your doctor.
3. HOW TO TAKE CIPROLON?
Your doctor will tell you how much CIPROLON should take and how often and for how long. This depends on the type and severity of the infection. The dosage may vary between 1 tablet per 24 hours until H tablet every 12 hours.
Tell your doctor if you have kidney problems, because they may require dose adjustment.
Treatment usually lasts 5 to 21 days but may be longer in severe infections. Take the tablets exactly as your doctor has told. If you are not sure how many tablets to take and how to take them, ask your doctor.
a. Swallow the tablets with plenty of fluid. Do not chew them because their taste is not pleasant.
b. Try to take your tablets at the same time each day.
in. You can take the tablets with regular intake of food or another. Calcium, which is a normal part of the diet will not seriously affect absorption.
Do not take the tablets CIPROLON dairy products such as milk or yoghurt or with fortified fruit juices (eg. Calcium fortified orange juice).
Remember to drink plenty of fluids when taking CIPROLON.
If you take more than you should CIPROLON
• If you take more than your prescribed dose, seek medical attention immediately. If possible, take your tablets or their packaging with you to show the doctor.
If you forget to take CIPROLON
• Take the normal dose as soon as possible and then continue on the prescribed schedule. However, if it is almost time to become next dose, skip the missed dose and continue with the scheme. Do not take a double dose to make up for a missed dose. Finish the full course of treatment.
If you stop taking CIPROLON
• It is important to complete the course of treatment, even if after several days already feel better. If you stop taking the medicine too soon your infection is possible to not be completely cured and the symptoms can reappear or worsen. It is possible to develop resistance to the antibiotic.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, CIPROLON can cause side effects, although not everybody gets them.
If any of the side effects gets serious, or if you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
Common side effects (between 1 and 10 in every 100 patients can get these):
• nausea, diarrhea
• joint pain in children
Uncommon side effects (between 1 and 10 in every 1000 patients can get these):
• fungal superinfection
• high levels of eosinophils, a type of white blood cells
• loss of appetite (anorexia)
• hyperactivity or agitation
• headache, dizziness, sleep problems or disorders of taste sensations
• vomiting, stomach pain, digestive problems or intestinal gas.
• increased levels of certain substances in the blood (transaminases and / or bilirubin)
• rash, itching or hives
• joint pain in adults
• impaired renal function
• unspecified pain, malaise or fever
• increase in alkaline phosphatase in the blood (a substance in the blood)
Rare side effects (between 1 and 10 in every 10,000 patients can get these):
• inflammation of the colon (colitis) linked ~ but with the use of antibiotics (in very rare cases can be fatal) (see. Point: Take special care with CIPROLON)
• changes in blood count (leukopenia, leukocytosis, neutropenia, anemia), increased or decreased number of platelets (responsible for blood clotting)
• allergic reactions, swelling (edema) or rapid swelling of the skin and mucosa (angioedema)
• high blood sugar (hyperglycemia)
• confusion, disorientation, anxiety reactions, abnormal dreams, depression or hallucinations
• sensation of tingling, unusual sensitivity to sensory stimuli, decreased skin sensitivity, tremors, convulsions (see. Point: Take special care with CIPROLON) or dizziness
• vision problems
• ringing in the ears, hearing loss, hearing impairment
• increased heart rate (tachycardia)
• dilation of blood vessels (vasodilation), low blood pressure or seizures
• shortness of breath, including asthmatic symptoms
• liver problems, jaundice (cholestatic jaundice) or hepatitis
• sensitivity to light (see. Point: Take special care with CIPROLON)
• aching muscles, sore joints, increased muscle tone or cramps
• renal failure, blood or crystals in the urine (see. Point: Take special care with CIPROLON), inflammation of the urinary tract
• fluid retention or excessive sweating
• abnormal one of the factors of coagulation (prothrombin) or elevated amylase enzyme
Very rare side effects (less than 1 in 10,000 patients can get these):
• certain type of reduction in the number of blood cells (hemolytic anemia); dangerous drop in white blood cells (agranulocytosis); decrease in the number of red and white blood cells and platelets (pancytopenia), which can be fatal, bone marrow suppression, which can also be fatal (see. point: Take special care with CIPROLON)
• severe allergic reactions (anaphylactic reaction or anaphylactic shock, which can be fatal - serum sickness) (see. Point: Take special care with CIPROLON)
• Mental Disorder (psychotic reactions) (see. Point: Take special care with CIPROLON)
• migraine, disturbed coordination, unsteady gait (violation
gait), impaired sense of smell (olfactory nerve disorders), increased pressure in the brain (intracranial pressure)
• changes in color perception
• inflammation of the wall of blood vessels (vasculitis)
• death of liver cells (liver necrosis) very rarely leading to life-threatening liver failure
• small pinpoint hemorrhages under the skin (petechiae) various skin eruptions (eg potentially fatal Stevens-Johnson and toxic epidermal necrolysis)
• muscle weakness, inflammation of the tendons, tendon rupture - especially of the large tendon in the back of the ankle (Achilles tendon) (see. Point: Take special care with CIPROLON); worsening of symptoms of myasthenia gravis (see. point: Take special care with CIPROLON)
Not known (from the available data can not be estimated)
• problems related to the nervous system such as pain, burning, tingling, numbness and / or weakness in the limbs
• severe heart rhythm disorders, irregular heartbeat.
5. HOW TO STORE CIPROLON
Do not store above 25 ° C!
Keep out of reach of children.
CIPROLON not use after the expiry date stated on the blister and carton after 'EXP'. The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. FURTHER INFORMATION
The active substance is ciprofloxacin.
Each tablet contains 750 mg of Ciprolon 873 mg
Ciprofloxacin hydrochloride monohydrate, equivalent to 750 mg of ciprofloxacin.
Other ingredients are: microcrystalline cellulose, corn starch, hydrogenated vegetable oil, sodium starch glycolate, colloidal silicon dioxide, magnesium stearate, talc, titanium dioxide (E 171), polyethylene glycol, hilromeloza, simethicone, polyacrylate dispersion
(copolymer of methacrylic acid - ethyl acrylate).
CIPROLON looks like and contents of pack
Each pack contains 10 tablets 750 mg CIPROLON.