CIPROFLOXACIN 250 mg. 20 tablets
Actavis Ciprofloxacin is an antibacterial product of the fluoroquinolone. The active substance is ciprofloxacin. Ciprofloxacin works by killing certain bacteria that cause infections.
Ciprofloxacin Actavis is used in adults to treat the following bacterial infections:
respiratory tract infections;
prolonged or repeated ear infections or sinus;
urinary tract infections;
infection of the testicles;
infections of genital mutilation;
infections of the gastrointestinal tract, and abdominal infections;
infections of skin and soft tissues;
infections of bones and joints;
infections in patients with severe neutropenia (very low number of leukocytes in the blood);
for the prevention of infections in patients with severe neutropenia;
Prevention of infection with Neisseria meningitidis;
inhaling anthrax spores.
If you suffer from a severe infection or one caused by more than one type of bacteria you may be assigned additional antibiotic treatment with Ciprofloxacin Actavis.
2. What you should know before using Ciprofloxacin Actavis
Do not take Ciprofloxacin Actavis if:
you are allergic (hypersensitive) to ciprofloxacin or other quinolone drugs or any of the other ingredients of the product listed in paragraph 6;
taking tizanidine (see. Section 2: Taking other medicines).
Tell your doctor if:
you have ever had kidney problems because your treatment needs to be corrected;
suffer from epilepsy or other neurological diseases;
have a history of tendon problems during previous treatment with antibiotics such as Ciprofloxacin Actavis;
have myasthenia gravis (a type of muscle weakness);
have a history of abnormal heartbeat (arrhythmias);
you are born with or have a family history of QT prolongation (which is observed on ECG, electrical recording of the heart), if you have an imbalance of salts in the blood (especially low potassium or magnesium in the blood) if you have a very slow heart beat (bradycardia), heart failure (heart muscle weakness) data for myocardial infarction, if you're a woman or an elderly patient, or are taking other drugs, leading to changes in the ECG (see. section Taking other medicines) .
While taking Ciprofloxacin Actavis
Tell your doctor immediately if you experience any of the following symptoms while taking Ciprofloxacin Actavis. Your doctor will decide whether treatment with Ciprofloxacin Actavis should be discontinued.
Severe, sudden allergic reactions (anaphylactic reaction / shock, angioedema). Even with the first dose, there is a small chance that you may experience a severe allergic reaction with the following symptoms: difficulty in breathing or dizziness, fainting, swelling of the face or throat. If you this happens, stop taking Ciprofloxacin Actavis and immediately contact your doctor;
Pain and swelling in the joints and tendinitis may occur occasionally, particularly if you are elderly and are also being treated with corticosteroids. At the first sign of pain or inflammation stop taking Ciprofloxacin Actavis and let rest the painful area. Avoid any unnecessary exercise, as this may increase the risk of tendon rupture;
If you suffer from epilepsy or other neurological conditions such as impaired blood supply to the brain or stroke, it is possible to get the effects associated with the central nervous system. If you this happens, stop taking Ciprofloxacin Actavis and immediately contact your doctor;
The first time you take Ciprofloxacin Actavis is possible to get psychiatric reactions. If you suffer from depression or psychosis, it is possible your symptoms get worse during treatment with Ciprofloxacin Actavis. If you this happens, stop taking Ciprofloxacin Actavis and immediately contact your doctor;
May develop diarrhea while taking antibiotics, including Ciprofloxacin Actavis, or even several weeks after you stop taking them. If it becomes severe or persistent or you notice that your stool contains blood or mucus, stop taking Ciprofloxacin Actavis, because this condition can be life threatening. Do not take medicines that stop or slow down bowel movements and contact your doctor;
Tell the doctor or laboratory staff that you are taking Ciprofloxacin Actavis if you take samples of blood or urine;
Ciprofloxacin Actavis may cause liver damage. If you notice symptoms such as loss of appetite, jaundice (yellowing of the skin extraction), dark urine, itching, or tenderness of the stomach, stop taking Ciprofloxacin Actavis and contact your doctor immediately;
Ciprofloxacin can reduce the number of white blood cells and your resistance to infection may be decreased. If you have an infection with symptoms such as fever and serious deterioration of your general condition, or fever with local infection symptoms such as sore throat / pharynx / mouth or urinary problems, you should immediately see your doctor. A blood test will establish the possible reduction of white blood cells (agranulocytosis). It is important to tell your doctor that you are taking ciprofloxacin;
Tell your doctor if you or a member of your family has a deficiency of glucose-6-phosphate dehydrogenase. This family history of impaired glucose utilization hidden risk of anemia after taking ciprofloxacin;
When taking Ciprofloxacin Actavis your skin becomes more sensitive to sunlight and ultraviolet rays. Avoid exposure to strong sunlight or artificial sources of UV light such as sunbeds.
Other drugs and Ciprofloxacin Actavis
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Do not take Ciprofloxacin Actavis together with tizanidine, because this may lead to side effects such as low blood pressure and sleepiness (see. "Do not take Ciprofloxacin Actavis").
Some of the drugs can interact with ciprofloxacin in the body. If you are taking Ciprofloxacin Actavis is both these medicines can influence the therapeutic effects or increase the likelihood of side effects.
Tell your doctor if you take:
drugs that prolong the QT-interval and lead to changes in the electrocardiogram (eg. antiaritmititsite quinidine, hydroquinidine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide, tricyclic antidepressants (such as amitriptyline and imipramii), certain antibiotics (belonging to the group of macrolides, such as erythromycin, clarithromycin, azithromycin), some antipsychotics;
probenecid (for gout)
omeprazole (used to treat ulcers);
tizanidine (for muscle spasms in multiple sclerosis);
methotrexate (for certain types of cancer, psoriasis, rheumatoid arthritis);
theophylline (for breathing problems)
phenytoin (for epilepsy);
cyclosporin (suppression of immunity);
Vitamin K antagonist (blood thinners) such as warfarin, acenocoumarol, phenprocoumon, fluindione;
glibenclamide (for diabetes);
duloxetine (for treating depression);
ropinirole (for Parkinson's disease);
lidocaine (for local anesthesia and an irregular heartbeat);
clozapine (an antipsychotic);
sildenafil (in violation of erection).
Ciprofloxacin Actavis may increase the levels of these medicines in your blood:
pentoxifylline (for circulatory disorders);
Some drugs reduce the effect of Ciprofloxacin Actavis. Tell your doctor if you are taking or plan to take:
phosphate-binding polymer (eg., sevelamer);
medicines or supplements containing calcium, magnesium, aluminum or iron / eg didanosine tablets).
If these products are important to you, take Ciprofloxacin Actavis about two hours before or no sooner than four hours after them.
Taking Ciprofloxacin Actavis with food and drink
If you are taking Ciprofloxacin Actavis during regular meals, do not eat or drink any dairy products (such as milk or yoghurt) or drinks with added calcium when you take the tablets, as they may affect the absorption of the active ingredient.
Pregnancy, lactation and fertility
If you are pregnant or breast-feeding, think you may be pregnant or planning to become pregnant, ask your doctor or pharmacist before taking this medicine.
It is preferable to avoid the use of Ciprofloxacin Actavis during pregnancy. Tell your doctor if you are planning to become pregnant.
Do not take Ciprofloxacin Actavis during breast feeding because ciprofloxacin is excreted in breast milk and may harm your child.
Driving and using machines
Ciprofloxacin Actavis may reduce your attention. May occur and some neurological side effects. So check how you react to Ciprofloxacin Actavis, before driving a vehicle or operating machinery. If in doubt, consult your doctor.
The film-coated tablets of 500 mg Ciprofloxacin Actavis contains lactose
If your doctor told you that you have an intolerance to some sugars, contact your doctor before taking this product.
3. How to take Ciprofloxacin Actavis?
Always take this medicine exactly as prescribed by your doctor or pharmacist. If you are not sure, ask your doctor or pharmacist.
Your doctor will tell you exactly how much Ciprofloxacin Actavis should take and how often and for how long. This depends on the type and severity of the infection. The dosage may vary between 1 tablet 24 hours to 3 tablets every 12 hours.
Tell your doctor if you have impaired kidney function, to allow it to adjust the dose.
The usual duration of treatment is 5 to 21 days. In severe infections, treatment can be continued. Take the tablets with plenty of liquid. Do not chew, because the taste is unpleasant. Try to take your tablets at the same time each day. Absorption of the drug does not depend on food intake. Calcium contained in the composition of food products will seriously affect their uptake. The tablets should not be administered with food and drinks rich in minerals (eg. Milk and yogurt, orange juice). Remember to drink plenty of fluids during treatment with Ciprofloxacin Actavis
If you take more dose Ciprofloxacin Actavis
If you take more than your prescribed dose, get medical help immediately. If possible, take your tablets or the packaging with you to show the doctor.
If you forget to take Ciprofloxacin Actavis
Take the normal dose as soon as possible and then continue on the prescribed schedule. If, however, has become almost time for next dose, skip the missed dose and continue under the scheme. Do not take a double dose to make up the missed dose. Finish the full course of treatment.
If you stop taking Ciprofloxacin Actavis
It is important to complete the course of treatment, even if after a few days already felt better. If you stop taking the drug too early your infection may not be completely cured and the symptoms reappear or worsen. It is possible to develop resistance (resistance) to the antibiotic.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Common side effects (likely to occur between 1 and 10 in every 100 patients):
joint pain in children.
Uncommon side effects (likely to occur between 1 and 10 in every 1,000 patients):
secondary infections caused by fungi (fungal superinfections);
high levels of eosinophils, a type of white blood cells;
loss of appetite (anorexia);
hyperactivity or excitement;
headache, dizziness, sleep problems or disorders of taste sensations;
vomiting, abdominal pain, digestive problems or intestinal gas;
elevated levels of certain substances in the blood (transaminases and / or bilirubin);
rash, itching or hives;
joint pain in adults;
impaired renal function;
nonspecific pain in the muscles and bones, feeling unwell (malaise), or fever;
elevations of alkaline phosphatase in the blood (a substance in the blood).
Rare side effects (likely to occur between 1 and 10 in every 10,000 patients):
inflammation of the colon (colitis) associated with the use of antibiotics (in very rare cases can be fatal) (see. Section 2: Take special care with Ciprofloxacin Actavis);
changes in the blood count (leukopenia, leukocytosis, neutropenia, anemia), increased or decreased number of platelets (responsible for blood clotting);
allergic reactions, swelling (edema), or rapid swelling of the skin and mucosa (angioedema);
high blood sugar (hyperglycemia);
confusion, disorientation, anxiety reactions, strange dreams, depression or hallucinations;
sensation of tingling, unusual sensitivity to stimuli of the senses, decreased skin sensitivity, tremors, seizures (see. Section 2: Take special care with Ciprofloxacin Actavis) or dizziness;
tinnitus, hearing loss, hearing impairment;
increased heart rate (tachycardia);
dilation of blood vessels (vasodilation), low blood pressure or fainting;
shortness of breath, including asthmatic symptoms;
liver disorders, jaundice or hepatitis;
sensitivity to light (see. Section 2: Take special care with Ciprofloxacin Actavis);
muscle pain, inflammation of the joints, increased muscle tone or cramps;
kidney failure, blood or crystals in the urine (see. Section 2: Take special care with Ciprofloxacin Actavis), urinary tract inflammation;
fluid retention or excessive potlivost;
abnormalities of one of the clotting factors (prothrombin) or increased levels of the enzyme amylase.
Very rare side effects (likely to receive less than 1 in every 10,000 patients):
certain type of reduction in the number of red blood cells (hemolytic anemia); a dangerous decrease in the number of white blood cells (agranulocytosis); decrease in the number of red and white blood cells and platelets (pancytopenia), which can be fatal, bone marrow suppression, which can also be fatal (see. Section 2: Take special care with Ciprofloxacin Actavis);
severe allergic reactions (anaphylactic reaction or anaphylactic shock, which can be fatal - serum sickness) (see. Section 2: Take special care with Ciprofloxacin Actavis);
mental disorders (psychotic reactions) (see. Section 2: Take special care with Ciprofloxacin Actavis);
migraine, disturbed coordination, unsteady walk (gait disturbance), disorder of sense of smell (olfactory nerve disorders), increased pressure in the brain (intracranial pressure);
changes in perception of colors;
inflammation of the wall of blood vessels (vasculitis);
pancreatitis (inflammation of the pancreas);
death of liver cells (liver necrosis) very rarely leading to life-threatening liver failure;
small petechial hemorrhages under the skin (petechiae); various skin rashes (eg the potentially fatal Stevens-Johnson and toxic epidermal necrolysis);
muscle weakness, inflammation of the tendons, tendon rupture - especially of the large tendon at the back of the ankle (Achilles tendon) (see. Section 2: Take special care with Ciprofloxacin Actavis); worsening of symptoms of myasthenia gravis (see. point 2: Take special care with Ciprofloxacin Actavis).
Not known (from the available data can not be estimated):
problems with the nervous system such as pain, burning, tingling, numbness and / or weakness in the limbs;
excessively rapid heartbeat, life-threatening irregular heartbeat, change in heart rhythm (called QT prolongation observed taking into account the electrical activity of the heart electrocardiogram).
If any of the side effects gets serious, or if you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
5. How to store Ciprofloxacin tablets Actavis?
At temperatures below 25 ° C.
Keep out of reach of children.
Do not use Ciprofloxacin Actavis after the expiry date stated on the blister and carton after "EXP". The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. Contents of the pack and other information
What Ciprofloxacin Actavis?
The active substance in one tablet Ciprofloxacin Actavis 250 mg of ciprofloxacin hydrochloride is / ciprofloxacin hydrochloride /, eq. 250 mg of ciprofloxacin / ciprofloxacin /.
Other ingredients are: corn starch; magnesium stearate; carmellose sodium; film coating / Opadry white Y-1-7000 /.