CIPRINOL 750 mg. 20 tablets
Excipients: propylene glycol, microcrystalline cellulose, croscarmellose sodium, hydroxypropyl methylcellulose, sodium starch glycolate, to moderately, colloidal silicon dioxide, magnesium stearate, talc, titanium dioxide (E171) .. Manufacturer and holder of the authorization: Krka, dd, Novo mesto, Slovenia
What is Ciprinol?
Ciprinol is a preparation of the quinolone family. It acts by disrupting the bacteria that cause various infections in the human body.
What is Ciprinol?
Medicinal product is indicated for the treatment of infections caused by ciprofloxacin-susceptible microorganisms:
urinary tract infection: uncomplicated (at polirezistentnost) and complicated infections of the upper or lower urinary tract;
respiratory tract infections: pneumonia (excluding pneumococcal pneumonia), acute and chronic bronchitis.
infections of the ear, nose and throat.
infections of the organs in the pelvis, infections of the reproductive system
infections of the organs in the abdomen and hepatobiliary infections, peritonitis, intra-abdominal abscesses, cholecystitis, cholangitis (combined administration of metronidazole or clindamycin);
infections of the bones and joints, osteomyelitis, septic arthritis;
infections of skin and soft tissue, infected wounds and ulcers, abscess, cellulitis, infections of the external auditory canal, infected burns;
severe systemic infections, sepsis, infections in patients with neutropenia (in combination with other antibiotics);
treatment of vectors of S. typhi and other salmonella; infectious diarrhea: if the pathogen is not isolated E.coli and conducting an antibacterial treatment is actually needed;
treatment and prevention of anthrax in people who have had contact with the spores of Bacillus anthracis. • prevention of infections in surgical procedures;, mainly in urology, gastroenterology (in combination with metronidazole) and in orthopedics;
prophylaxis in neutropenic patients and in patients taking drugs that lower immunity.
If your condition is severe, your doctor may prescribe medicine in infusion for the first few days of your illness, and later you can continue treatment with the tablets.
Who should not take Ciprinol?
Tell your doctor if you have any chronic disease, metabolic disorders or if you are hypersensitive or taking other medicines.
You should not take Ciprinol, if you are hypersensitive to the active substance, ciprofloxacin, or to any of the excipients, or you are hypersensitive to other drugs of the quinolone family. You should not take Ciprinol, if you are pregnant or breast-feeding. Ciprinol not be prescribed to children and adolescents due to lack of experience of the use of the drug in these age groups. The medicinal product may be used in this age only in the event that the potential benefit to justify the risk to the fetus.
The doctor may prescribe Ciprinol these patients except when the expected benefit to the patient is greater than the potential risk
Such exemptions may be, for example, pregnant women or children who have been in contact with spores of Bacillus anthrcis.
Special warnings and special precautions for use
Tell your doctor if you have epilepsy or other disease of the central nervous system (decreased threshold to convulsions, cases of convulsions, improper blood supply to the brain, or if you are recovering from stroke). There is a greater risk of adverse reactions in these diseases. In certain patients can be observed effects on the central nervous system such as dizziness, confusion, nervousness, depression, and less frequently psychosis with ideas of suicide even when the first dose ciprofloxacin. If you notice these symptoms, tell your doctor. Hypersensitivity reactions occur very rarely after the first dose. Tell your doctor if your skin itch or rash, or if you suddenly experience difficulty breathing. If you have kidney failure, you have to take a smaller dose of medicine or need to take the usual dose, but at a longer interval.
Prerorachva to take more fluids during treatment with Ciprinol. This will prevent the formation of crystals in the urine. The doctor will tell you how much fluid a day are appropriate for you. If you have an inherited disease which results in a deficiency of glucose-6-phosphate dehydrogenase, in the treatment Ciprinol may experience anemia or a yellowing of the skin. The skin can not yellow during treatment in case of previous liver damage.
During treatment with Ciprinol skin may become sensitive to sunlight and artificial ultraviolet light. Therefore, we recommend that you do not expose it to sunlight or artificial ultraviolet light during treatment with Ciprinol. Adoption of antimicrobials can cause growth of resistant bacteria. Some of them can cause severe and persistent diarrhea. In that case, you should consult your doctor. Tell your doctor if you experience pain in the tendons or signs of tendinitis (inflammation of the tendons). Patients should avoid heavy exercise during treatment with Ciprinol.
In elderly patients who have received treatment with corticosteroids has been observed occasionally irritation or rupture of the tendon (often Achilles).
Application of Ciprinol with food and drink
You should not drink alcohol during treatment.
Pregnancy and lactation
Consult your doctor before taking any medicine. The risk of adverse effects in the fetus can not be ruled out. If you are pregnant, your doctor may prescribe Ciprinol exceptionally, where the potential beneficial effects in the mother outweighs the potential risk to the fetus. Breast-feeding should be discontinued during treatment with tsitrofloksatsin.
Effects on ability to drive and use machines
Ciprinol can weaken wool reactions should therefore be careful in managing a car or operate machinery until you know how your body reacts to the drug. Side effects are increased when administered with alcohol.
What may interact with other medicines Ciprinol?
Tell your doctor or pharmacist if you are taking or have taken any medicines, even those that are without a prescription.
If the taking of medicinal products heartburn - antacids that contain aluminum, magnesium or calcium, or sucralfate tsshgrofloksatsin absorption is reduced. Therefore, these patients are recommended to take Ciprinol four hours before antacids and / or sucralfate, or 2 to 4 hours after its administration.
If taking theophylline during treatment with Ciprinol, side effects may occur because the levels of theophylline in the blood can be increased. The doctor will weigh the level of theophylline in blood and may prescribe a lower dose.
Co-administration with cyclosporine increases the risk of renal impairment, therefore a measurement of the amount of cyclosporine in the blood. If you are taking medicines for blood clotting simultaneously Ciprinol, their effect may be enhanced to produce bleeding.
Tell your doctor if you have diabetes and are treated with glibenclamide. Co-administration with Ciprinol may further lower blood sugar.
If you suffer from epilepsy and was treated with phenytoin, coadministration Ciprinol may be changing or decreased phenytoin levels in the blood.
Concurrent use of some anti-inflammatory agents and high doses of quinolones can be observed convulsions (seizures).
Dosage and method of administration
Strictly follow the doctor's instructions. Should not change the dosage or stop treatment without consulting a doctor. Your doctor will adjust the dosage according to your disease, tolerance to the medicine and treatment response. Ciprinol tablektki can be administered in doses of 250 mg, 500 mg or 750 mg twice daily.
Swallow the tablets whole, c glass of water or tea.
In acute gonorrhea enough single dose of 250-500 mg.
The doctor may prescribe Ciprinol children to treat or prevent anthrax in doses of 15 mg / kg weight twice daily.
The doctor may prescribe Ciprinol tablets after you received the drug as an infusion for several days.
The duration of treatment depends on the severity of the disease, the clinical and bacteriological results.
Uncomplicated urinary tract infections are usually treated three days; complicated urinary tract infections and other infections to 14 days. Chronic bacterial prostate usually treated for 12 weeks, infections of the bone and joints - of 4 to 6 weeks, salmonella batsilonositelstvo - 4 weeks, infectious diarrhea from 5 to 7 days to 14 days -ponyakoga. In case of contact with anthrax spores, Ciprinol must be given 60 days.
For the prevention of infections in surgical procedures, 500 to 750 mg Ciprinol should be taken half to one hour before surgery.
If you have impaired kidney function or are an elderly patient doctor may prescribe a lower dose than that which is normal for you.
If you have the impression that the effect of the drug is too strong or weak, say it to your doctor or pharmacist. If you forget to take Ciprinol
If you forget to take a dose, take it as soon as you remember, unless it is too close to the time for the next dose.
Do not take a double dose to make up for a missed dose.
Risk of discontinuation of Ciprinol
If you stop taking Ciprinol too early, the disease can recur.
If you take more than you need Ciprinol
If you take too high doses, they can cause nausea, vomiting, diarrhea, headache and dizziness; in severe cases, confusion, tremors, hallucinations and convulsions (seizures) .If you take an overdose, consult your doctor or pharmacist immediately.
Possible side effects
As with all medicinal products in the treatment of Ciprinol may experience adverse reactions. The most frequently reported were nausea, diarrhea, and rash.
Very rarely can be observed some other gastrointestinal side effects (vomiting, abdominal pain, flatulence, loss of appetite or exceptionally persistent diarrhea - pseudomembranous colitis).
Side effects on the central nervous system: dizziness, headache,, fatigue, agitation, insomnia, anxiety, depression, convulsions, anxiety, hallucinations, psychosis with ideas of suicide and sensory disturbances such as visual disturbances, bad taste, noise ears and signs of increased intracranial pressure.
Hypersensitivity reactions may occur with any medicine. They can be mild (rash, redness, itching), severe reactions (fever, swelling of the face, photosensitivity) or very rarely, severe reactions including anaphylactic reactions require immediate action. Cardiovascular side effects: increased heart rate, nausea, flushing and sweating, migraine.
Ciprinol may cause an increase in blood glucose levels and, therefore, you should tell your doctor if you feel better and are more thirsty than usual. Quinolone agents can cause bone pain and muscle inflammation and rupture of tendons. This happens very rarely and usually when administered with corticosteroids. If you feel pain in the tendons, tell your doctor.
If you suffer from myasthenia gravis, treatment Ciprinol may worsen your condition. Ciprinol may affect certain laboratory tests of blood and urine tests that indicate liver or kidney damage. The number of red and white blood cells can be changed. Rarely, your skin may become yellowish; coloration of the urine can also be changed.
Prolonged or repeated treatment with Ciprinol can cause infections by resistant bacteria or fungi.
Treatment should be discontinued if severe adverse reactions (especially severe hypersensitivity reactions, pseudomembranous colitis, severe disorders of the central nervous system, hallucinations or pain in the tendons) .If you notice any side effects vklyuchitnelno those not mentioned in this leaflet, please please tell your doctor or pharmacist.
Storage and shelf life
Keep out of reach of children.
Do not store above 30 ° C.
Do not use after the expiry stated on the label.
20 tablets of 750 mg