CEC 500 mg. 10 tablets
CEC 500 mg. 10 tablets
What is the active ingredient?
1 effervescent tablet contains 524.48 mg cefaclor monohydrate, corresponding to 500 mg cefaclor.
What else contain CEC 500 effervescent tablets?
citric acid, macrogol 6000,. sodium cyclamate, sodium dihydrogen citrate, sodium hydrogen carbonate, - sodium sulfate, povidone K25, sodium saccharin, flavors (lemon).
Lekarstevena form and packing:
Original packages containing 10 or 20 tablets
What is CEC 500 effervescent tablets?
CEC 500 effervescent tablets, an antibiotic belonging to the group of cephalosporins, which are applied, for the treatment of bacterial infections.
What is it used CEC 500 mg effervescent tablets?
For the treatment of acute and chronic infections exacerbated with varying degrees of severity, which are caused by. cefaclor sensitive bacteria and disease are suitable for administration of the antibiotic orally.
For treating these infections are shown:
- The upper and lower respiratory tract
- Ear, Nose and Throat - as otitis media (otitis media), sinusitis, tonsillitis (tonsillitis) and pharyngitis (sore throat)
- Kidney and lower urinary tract
When you must not take CEC 500 effervescent tablets?
You should not take CEC 500 if you are allergic to cefaclor, other antibiotics of this group (cephalosporins) or any of the ingredients.
If you have had hypersensitivity reactions to penicillin derivatives, tell your doctor as possible be allergic to cephalosporins (cross-allergy).
What precautions should be taken when taking CEC 250 effervescent tablets?
Tell your doctor if you suffer from overt allergy or bronchial asthma, as can be expected allergic reactions to the product.
Tell your doctor if you suffer from severe gastrointestinal disorders accompanied by vomiting and diarrhea, as in these cases it is not providing adequate absorption and efficacy CEC 500.
CEC 500 may influence the effect of certain products that inhibit blood clotting (coumarin-type anticoagulants). In such cases must be carefully monitored indicators of coagulation. If necessary, the doctor will reduce the dose of CEC.
If you need to examine your urine and / or blood, please tell your doctor that you are taking CEC 500, because certain tests can give inaccurate results (eg. Non-enzymatic methods for the determination of sugar and protein in the urine, Coombs test ).
1 effervescent tablet contains 17,2 mmol (398 mg). This should be taken into consideration if you are on a controlled sodium diet.
Other products that interfere with the effect of 500 CEC effervescent tablets, or may be influenced by the preparation?
Tell your doctor if you are taking or have recently taken any medicines, even those not prescribed.
CEC 500 does not have to be combined - where possible - with drugs inhibiting the growth of a bacterium (e. Chloramphenicol, erythromycin, sulfonamides, or tetracyclins), since the effect of the WEC 500 can be reduced.
Probenecid (a product for the treatment of gout)
The additional use of probenecid leads to suppressing the secretion of cefaclor by the kidneys, resulting in yielding higher concentrations of cefaclor and prolonged presence in the blood.
In patients receiving concomitant CEC 500 and medicines that inhibit blood coagulation (coumarin-type anticoagulants) were observed occasionally prolonged prothrombin time with or without bleeding Please note that these figures apply to the recently approved drugs.
What foods and drinks you should avoid?
No information on foods and drinks that should be avoided.
What should I take into account children and elderly patients on CEC 500 effervescent tablets?
CEC 500 should not be given to premature infants because there is not enough clinical data.
What special precautions should be taken during pregnancy and lactation?
Observations in pregnant women have not shown evidence of harm to the fetus. Studies in animals have found embryo / fetotoxic effects.
However, in pregnancy, particularly during the first three months of pregnancy CEC 500 should be taken only if the doctor considers it necessary, the treatment and after careful consideration of the benefit / risk ratio.
During lactation CEC 500 should be used only in very urgent need of treatment because the active ingredient may pass into breast milk. Breastfed infant may develop hypersensitivity to the active ingredient and to experience diarrhea or colonization of the intestinal mucosa with fungi (e.g.. Blastomitseti).
What to be aware when driving or operating machinery?
So far it is not known to affect CEC concentration and reaction speed, but side effects such as low blood pressure or vertigo may increase the risk of a breach of those activities.
Dosage, method and duration of administration
It is recommended that the following dosage unless your doctor has prescribed CEC 500 effervescent tablets in different dosing regimen. Please follow these instructions for use. Otherwise CEC 500 will not work correctly.
How much and how often you can take CEC 500 effervescent tablets?
Adults and children over 10 years, unless otherwise prescribed, should receive 1 effervescent tablet 3 times a day (corresponding to 500 mg of cefaclor three times daily).
The dose may be doubled for severe infections (like pneumonia) and infections caused by less sensitive bacteria. In some cases, adults take up to 8 effervescent tablets (corresponding to 4 g cefaclor day) and they were well tolerated. This dose should not be exceeded.
In mild infections such as uncomplicated infections of the lower urinary tract is
recommends half effervescent tablet 3 times daily (corresponding to 250 mg of cefaclor 3 times daily).
In the treatment of acute gonorrhea urethritis in men and women is assigned a dosage of 6 effervescent tablets (corresponding to 3 g of cefaclor), but possibly combined with 1 g probenecid.
Children 6 to 10 years if there is no other prescription should take 1/2 effervescent tablet 3 times a day (corresponding to 250 mg of cefaclor three times daily).
In severe infections, inflammation of the middle ear (otitis media) or infections caused by less sensitive bacteria need a dose of 1/2 of an effervescent tablet 4 times a day (corresponding to 250 mg of cefaclor 4 times daily).
Otitis media may also be treated with 1 effervescent tablet 2 times per day (corresponding to 500 mg of cefaclor 2 times a day). In mild infections such as uncomplicated infections of the lower urinary tract is sufficient dosage of half an effervescent tablet 2 times per day (corresponding to 250 mg of cefaclor 2 times a day).
Children under six years if there is no other prescription should take 30 mg cefaclor / kg bw / day in three divided doses (10 mg cefaclor / kg body weight three times daily).
In the case of severe infections, otitis media, or infections caused by less sensitive pathogens, recommended 40 to 50 mg of cefaclor / kg body weight / day for a maximum of 1 g of cefaclor per day. In the case of otitis media, the total daily dose can be administered in two divided doses every 12 hours.
In mild infections such as uncomplicated infections of the lower urinary tract is sufficient dosage of 20 mg of cefaclor / kg body weight / day, divided into 2-3 single doses every 8 or 12 hours.
Dosage in patients with impaired renal function
CEC 500 effervescent tablets can be applied even in patients with renal impairment without dose adjustment. Haemodialysis decreases serum half-life by 25-30%. In patients on regular hemodialysis before dialysis should be administered a starting dose of 250 mg to 1 g. Maintenance dosage adopted between dialysis treatments is the same as in non-dialysis.
When and how you can take CEC 500 effervescent tablets?
Dissolve the effervescent tablets in a glass with 3-4 tablespoons of water, stir well and drink it immediately. Then drink some water again.
You can take CEC 500 effervescent tablets with a meal, which does not violate absorption.
How long can you take CEC 500 effervescent tablets?
Generally CEC 500 effervescent tablets should be taken from 7 to 10 days, or at least 2-3 days after disappearance of the symptoms of the disease. In the treatment of infection with beta-hemolytic streptococci recommended treatment duration of at least 10 days in order to prevent late complications (e. Rheumatic fever, and glomerulonephritis).
The duration of application are determined by your doctor.
What should I do if WEC 500 effervescent tablets were taken in very large quantities (intentional or unintentional overdose)?
So far there are no reported cases of intoxication with cefaclor. If accepted large quantities of product you should consult a doctor. Please keep the packaging of medicine that your doctor can determine the accepted active ingredient.
What should you do if you take more than the prescribed dose CEC 500 effervescent tablets or you missed taking the drug?
If you forgot accepted, please take your dose as soon as possible. If you did not receive the drug several times, you should consult your doctor to monitor the situation and take appropriate action.
What you should know if you are discontinued or have it terminated prematurely?
If you discontinued prematurely, the risk of relapse.
What side effects can cause the application of CEC 500 effervescent tablets?
Like all medicines, administration of 500 CEC can cause side effects
Blood and blood cells
Very rarely were no changes in the number of blood cells (eosinophilia, leukopenia, lymphocytosis, thrombocytopenia, -neutropeniya uncommon, and in some cases, aplastic and haemolytic anemia). These side effects are normalized spontaneously after treatment. Infrequently observed a significant reduction of white blood cells (agranulocytosis).
Liver and bile ducts
Uncommon may occur reversibly increase of liver enzymes in the serum (transaminases, alkaline phosphatase).
Have been reported instances of transient liver cell damage (hepatitis) and disorder swelling of bile (jaundice).
Uncommon disorders may arise as a lack of appetite, abdominal pain, diarrhea, vomiting, heaviness in the stomach, nausea or loose stools. These events are mild and usually disappear during or after therapy interruption and.
As with other broad spectrum antibiotics, may cause intestinal inflammation (colitis), including psevdomemranozen colitis.
Kidney and urinary tract
Infrequently may cause acute inflammation of the kidney (acute interstitial nephritis), but this resolved after completion of therapy. It was also observed a slight increase in blood urea or creatinine.
Reported have been uncommon cases of transient hallucinations, hyperactivity, nervousness, insomnia, drowsiness, dizziness or embarrassed behavior. As with other drugs of this class (cephalosporin antibiotics) can not be excluded increased tendency to convulsions.
Often possible allergic skin reactions (eg. Reddening skin burning sensation (rash), itching, hives, swelling and blistering (urticarial exanthema), rash similar to measles (maculopapular, morbilliform exanthema).
Other symptoms of hypersensitivity reactions may be increasing the number of eosinophilic cells (eosinophilia), a positive test Coomb (detecting certain types of antibodies in the blood) (angioneurotic) edema, drug fever, and inflammation of the vagina.
Reported cases were uncommon, serum sickness-like -multiformena erythema (redness different manifestations of the skin) or above skin reactions accompanied by joint symptoms and fever. In these cases, in contrast to serum sickness, lymphadenopathy and proteinuria have been observed only rarely. There are no circulating antibodies.
In general, these allergic reactions occur during or after repeated treatment with cefaclor (more common in children than in adults) and disappear a few days after discontinuation of treatment.
Severe hypersensitivity reactions can be expressed by a fall in blood pressure to life-threatening shock, swelling of the face (facial edema) ', increased heart rate, swelling of the larynx with the tightening of the airways, difficulty breathing, swelling of the tongue. In individual patients, these reactions occurred after the first administration of the drug. In appearance they need immediate medical attention.
Uncommon cases of severe skin manifestations of life-threatening systemic reactions (Syndrome Stevens-Johnson, exfoliative dermatitis have been reported in association with administration of 500 effervescent tablets CEC
Other side effects
After taking SES 500 effervescent tablets occasionally been reported transient increases in blood pressure.
Prolonged or repeated administration of cefaclor can lead to secondary infections (superinfection) and colonization by resistant bacteria cefaclor or the development of a fungal infection (blastomitseti).
If you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
What measures should be taken in relation to the side effects?
If during or after the medicine is observed severe or persistent diarrhea, please consult your doctor as this may be a manifestation of a serious intestinal disease (pseudomembranous enterocolitis), which should be treated immediately. Please do not take self with drugs that inhibit gastrointestinal motility. If you experience sudden severe hypersensitivity reactions, please consult your doctor as you may need immediate treatment.
The shelf life of the drug printed on the packaging.
Do not use after the expiry date stated on the packaging.
How should I store CEC 500 effervescent tablets?
Please store the product in the original container, tightly closed in order to protect from moisture.
Keep at temperatures below 25 ° C.
Keep out of reach of children!