CANDECARD 16 mg. 30 tablets
CANDECARD 16 mg. 30 tablets
What is Candecard and what it is used
Candecard belongs to the group of drugs known as antagonists of angiotensin II. These drugs act by expanding the blood vessels, the heart may be easier to pump blood thereto. Candecard tablets are used:
• for the treatment of high blood pressure (hypertension);
• to treat heart failure (condition in which the heart can not pump enough blood to meet the body's needs);
2 Before you take Candecard
Do not take Candecard if:
• you are allergic (hypersensitive) to candesartan cilexetil or any of the other ingredients of the drug (see. Section 6)
• have severe liver or biliary obstruction (problems with drainage of bile from the gall bladder)
If you are pregnant after the third month. (It is also to avoid the use of Candecard and early pregnancy - see. Section "Pregnancy and lactation").
Candecard should not be given to children.
If you think any of these apply to you, talk to your doctor or pharmacist.
Take special care with Candecard
Before you take Candecard tell your doctor if:
• have heart problems, liver or kidney
• if you have had a stroke
• you have recently had a kidney transplant
• you are on hemodialysis
• have low blood pressure
• vomit, have recently vomited or have diarrhea
• suffer from a disease of the adrenal gland
(Conn's syndrome or hyperaldosteronism)
• need surgery as Candecard can cause a drop in blood pressure when combined with anesthetics
You should tell your doctor if you are pregnant or might become pregnant. Candecard not recommended in early pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used at that stage (see section "Pregnancy and lactation").
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes herbal medicines and medicines obtained without a prescription. Candecard can interfere with other medicines and other medicines can affect Candecard. If you are taking certain medications, may need your doctor sometimes do blood tests.
In particular, tell your doctor if you are taking any of the following medicines:
• other medicines that help lower your blood pressure, including ACE inhibitors such as enaparil, captopril, or lizonopril ramipiril
• drugs like ibuprofen, naproxen or diclofenac, known as non-steroidal anti-inflammatory drugs (NSAIDs)
• drugs such as celecoxib or etoricoxib, known as COX-2 inhibitors
• aspirin if you are taking more than 3 g daily
• potassium supplements or salt substitutes containing potassium
• heparin (blood thinners)
• water tablets (diuretics)
• lithium (a drug for the treatment of mania and depression).
Taking Candecard with food and drink
Food does not affect the blood pressure lowering effect of candesartan.
Pregnancy and lactation
You should tell your doctor if you think you are (or might become) pregnant. In general, your doctor will advise you to take another medicine instead Candecard as Candecard not recommended in early pregnancy and may cause serious harm to your baby if used after 3 months of pregnancy.
Tell your doctor if you are breast-feeding or about to start breast-feeding. Candecard not recommended for nursing mothers, so your doctor may choose another treatment for you if you wish to breast-feed, especially if your baby is newborn, or was born prematurely.
Ask your doctor or pharmacist before taking any medicine.
Driving and using machines
Candecard not affect the concentration but different effects, such as dizziness or fatigue associated with lowering blood pressure may also occur in some patients, especially at the beginning of treatment or when increasing the dose. If you get such reactions, your ability to drive or operate machinery may be impaired.
Important information about some of the ingredients of Candecard
Lactose is one of the ingredients of this medicine. If your doctor has told you that you have an intolerance to some sugars before taking this medicine, you should contact your doctor.
H. How to take Candecard
Always take this medicine exactly as prescribed by your doctor. If you are not sure, ask your doctor or pharmacist. Candecard can be used alone or with other medicines that lower blood pressure. Candecard usual doses are:
High blood pressure:
The recommended starting dose and usual maintenance dose is 8 mg once daily. The dose may be increased to 16 mg once daily. If blood pressure is not adequately controlled after 4 weeks of treatment with 16 mg once daily, the dose may be further increased to a maximum of 32 mg once daily. If this dose does not achieve blood pressure control, it is recommended that a combination of thiazide diuretics or calcium channel blockers. Treatment should be adjusted according to blood pressure response. Maximum antihypertensive effect is attained within 4 weeks after beginning treatment.
Use in renal impairment:
The starting dose in patients with impaired renal function is 4 mg, including in patients on hemodialysis. The dosage should be determined by reference to the response. Experience in patients with very severe renal impairment or end-stage renal disease (creatinine <15 ml / min) is limited.
Use in hepatic impairment:
In patients with mild to moderate hepatic impairment is recommended initial dose of 2 mg once daily. The dose should be adjusted according to the response. There is no experience in patients with severe hepatic impairment.
Use in the elderly
It is not necessary initial dose adjustment in elderly patients.
Use in patients with intravascular volume depletion:
One may consider the use of an initial dose of 4 mg in patients at risk of hypotension, such as patients who are likely to be reduced volume
Use in black patients antihypertensive effect of candesartan cilexetil is less in black patients than in non-black patients. Therefore, in black than non-black patients may often need an increased dose of candesartan cilexetil and apply combination therapy to control blood pressure.
The usual recommended starting dose of candesartan cilexetil is 4 mg once daily. Increasing the dose to the target dose of 32 mg once daily or the highest tolerated dose was carried out by doubling the dose at intervals of at least 2 weeks.
It is not necessary initial dose adjustment in elderly patients or patients with intravascular volume depletion, renal impairment or mild to moderate hepatic impairment.
Candesartan may be administered with other treatments for heart failure, including ACE inhibitors, beta-blockers, diuretics and digitalis or a combination of these products.
Take your / your tablet / and a glass of water, preferably at the same time every day, before or during a meal.
Candecard is not suitable for use by children.
If you take more than you should Candecard
If you (or someone else) take more than necessary, you should immediately contact the nearest emergency room or call your doctor. The most likely effect of overdose is low blood pressure. If there is a significant decrease in blood pressure (may show symptoms such as dizziness or faintness) can help if you stand in a supine position with legs raised.
However, if the symptoms are serious, take with you this leaflet, any remaining tablets and the packaging and take them to the hospital or your doctor to know what these tablets you take.
If you forget to take Candecard
It is important to take your medicine every day. However, if you forget to take one or more doses, take it as soon as you remember and then continue its normal mode. Do not take a double dose to make up for a missed dose.
If you stop taking Candecard
Always consult your doctor if you should stop taking this medicine. You may need to continue taking this medication even if you feel well.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4 Possible side effects
As with all medications, Candecard can cause side effects, although not everyone gets them
These side effects are very rare (affects less than 1 in 10,000 people). However, if you notice any of these side effects, contact your doctor immediately:
• swelling of the face, lips, mouth, tongue, eyes or throat
• difficulty in breathing
• dizziness or fainting
These are signs of serious reaction, which must be treated immediately, generally in a hospital.
Contact your doctor immediately in case of:
• jaundice (yellowing of the skin and / or eyes)
Other possible side effects: Common (affects less than 1 in 10 people):
• dizziness, spinning sensation (vertigo)
• headache, respiratory tract infections
• low blood pressure
• increased levels of potassium in your blood, especially if you already suffer from kidney problems or heart failure
• impact on the kidneys, especially if you already suffer from kidney problems or heart failure
Very rare (affects less than 1 in 10,000 people):
• back pain, joints and muscles
• skin rash, hives
• reduced number of your red or white blood cells or platelets you. It is possible that you may occur fatigue, infection, fever or easy bruising impact. Your doctor may occasionally do blood tests to check whether Candecard not affect in any way your blood.