CALUTIDE 50mg. 10 tablets
CALUTIDE 50mg. 10 tablets
What is Kalutid and what it is used?
Pharmacotherapeutic group: Hormone antagonists and related agents, antiandrogens. Bicalutamide is used to treat prostate cancer in an advanced stage. It is with a medicine known as an analog of luteinizing hormone-releasing hormone (LHRH) - additional hormonal therapy - with or accompanying the surgical removal of the testicles.
Bicalutamide belongs to a group of medicines known as nonsteroidal antiandrogens. The active substance bicalutamide block undesired effect of male hormones (androgens), and thus inhibits cell growth in the prostate.
2 What you should know before taking Kalutid?
Do not take Kalutid:
• If you are allergic to bicalutamide or any of the other ingredients of this medicine (listed in Section 6).
• If you are female, adolescent or child
• If you are taking terfenadine or astemizole (for hay fever or allergies) or cisapride (for stomach disorders) with Bicalutamide 50 mg tablets.
Kalutid should not be taken by women or children.
Warnings and Precautions
Talk to your doctor or pharmacist before taking Kalutid.
• If the functioning of your liver is moderately or severely impaired. In this case, the drug should be taken only after your doctor has carefully considered the potential benefits and risks. If this is the case, your doctor will perform tests of liver function (bilirubin, transaminases, alkaline phosphatase). occurrence of serious liver dysfunction, treatment with bicalutamide should be discontinued.
• If your kidney function is severely impaired. In this case, the drug should be taken only after your doctor has carefully considered the potential benefits and risks.
• If you have diabetes and are already taking LHRH analog. Drugs of this type are goserelin, buserelin, leuprorelin and triptorelin.
Other medicines and Kalutid:
Tell your pharmacist if you are taking, have recently taken or might take other medicines.
Bicalutamide may be administered in conjunction with any of the following medications:
Terfenadine or astemizole (for hay fever or allergy), cisapride (for stomach disorders) If you are taking bicalutamide with one of these drugs, the effect of bicalutamide and other medicines may be affected. Please consult your doctor before taking any of these medicines with bicalutamide:
- Warfarin or any such medication to prevent blood clotting.
- Ciclosporin (used to suppress the immune system in order to prevent and treat the rejection of a transplanted organ or bone marrow)
- Cimetidine (used to treat stomach ulcers)
- Ketoconazole (used to treat fungal infections of the skin and nails)
- Blockers of calcium channels (for the treatment of high blood pressure)
Taking Kalutid with food and drink:
Taking food and drink does not affect your treatment with Kalutid. Pregnancy and lactation:
Kalutid is contraindicated in women and should not be given to pregnant women or nursing mothers. Ask your doctor or pharmacist before taking any medicine.
Driving and using machines:
It is unlikely that your medicine can adversely affect your ability to drive or operate machinery. However, some people may sometimes feel dizzy or sleepy after taking Kalutid. If this happens to you, you should approach with caution to performance of such tasks.
Kalutid contains lactose
If your doctor has told you that you have an intolerance to some sugars, consult him before taking this medicine.
3 How to take Kalutid?
Always take this medicine exactly as prescribed by your doctor or pharmacist. If you are not sure, ask your doctor or pharmacist.
The usual dose is one tablet Kalutid day. Swallow the tablet whole with water. Try to take the tablet at the same time each day.
If you take more than you should Kalutid
If you take more than the prescribed dose, contact your doctor. In case of overdose, immediately go to the nearest hospital. If possible, take your tablets or the box with you to show the doctor what you have taken.
If you forget to take Kalutid
If you forget to take your medicine, take your dose as soon as you remember and then take your next dose at the usual time. Do not take a double dose to make up for a forgotten tablet. If you stop taking Kalutid
Do not stop taking your tablets even if you feel well, unless your doctor tells you to. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4 Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
These are uncommon (affects less than 1 in 100 people). Symptoms may include sudden onset of:
• rash, itching or hives on the skin
• swelling of the face, lips, tongue, throat or other parts of the body
• shortness of breath, wheezing or difficulty breathing
If this happens, seek medical attention immediately.
Also tell your doctor immediately if you notice any of the following:
Very common (affects more than 1 in 10 people):
• abdominal pain
• blood in urine
Common (affects less than 1 in 10 people):
• Yellowing of the skin or whites of the eyes (jaundice). These may be signs of liver problems or rare (affects less than 1 in 1000 people) liver failure.
Uncommon (affects less than 1 in 100 people):
Severe shortness of breath or shortness of breath that suddenly get worse. This can be accompanied with coughing, high temperature (fever). These may be symptoms of inflammation of the lungs, known as "interstitial lung disease".
Very common (affects more than 1 in 10 people)
• low red blood cell count (anemia). This can make you feel tired or look pale.
• bloating and breast tenderness.
• breast enlargement in men
• feeling weak
• hot flashes
• vomiting (nausea)
Common (affects less than 1 in 10 people)
• loss of appetite
• wind (flatulence)
• weight gain
• dry skin
• skin rash
• Problems getting an erection (erectile dysfunction)
• decreased sex drive
• hair loss
• re-emergence of the hair or hair growth further
• chest pain
• reduced function of the heart
• heart attack
• liver toxicity
• changes in liver enzymes
Sometimes Kalutid may be related to changes in your blood, which may require your doctor to do some blood tests.
If you get any side effects, tell your doctor or pharmacist. This includes all listed in this leaflet.
5 How to store Kalutid?
• This medicine does not require any special storage conditions.
• Keep out of reach of children.
• Do not use Kalutid after the expiry date stated on the carton and blister (EXP / EXP).
Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
b. Package Contents and more information
Lactose monohtsdrat, crospovidone (micronized), povidone, corn starch, sodium lauryl sulfate, magnesium stearate, silica colloidal anhydrous, Opadry White Y-1-7000, distilled water
Kalutid looks like and contents of the pack
Kalutid 50 mg tablets are white to off-white, round, biconvex, film-coated tablets.
Kalutid 50 mg tablets are packaged in blister pack of 10.