Brufen. 800 mg. 30 tablets
Brufen. 800 mg. 30 tablets
Brufen Retard WHAT IS AND WHAT IT IS USED
Brufen Retard belongs to a group of medicines called NSAIDs (nonsteroidal anti-inflammatory drugs). Brufen Retard relieves pain, reduces fever, relieves fever and has anti-inflammatory effect.
Brufen Retard is used for the symptomatic treatment of pain and inflammation Simptomatachno treating pain and inflammation in rheumatic diseases. (rheumatoid arthritis and osteoarthritis) in adults.
2 Before you take Brufen Retard
Do not take Brufen Retard:
If you are allergic (hypersensitive) to ibuprofen or excipients;
If you are in the last trimester of pregnancy;
If you have increased bleeding;
If you have severe liver or kidney disease;
If you have severe heart failure;
If you have gastric or duodenal ulcers or have had gastric or duodenal ulcers treated with Brufen Retard or similar products;
If you have had an allergic reaction (such as difficulty in breathing, nasal congestion, rash) to aspirin or other NSAIDs.
Take special care with Brufen Retard
Always aim for the lowest possible dose for the shortest treatment course to reduce the risk of side effects. Usually doses higher than recommended may increase the risk. This means that the combination of NSAIDs at a dose should be avoided;
Patients who have or have had the following diseases or symptoms should consult a doctor before starting treatment with Brufen Retard: systemic lupus erythematosus (CTD), impaired renal or hepatic function, mild to moderate heart failure, asthma, inflammatory bowel disease, previous gastric ulcer or increased bleeding of another nature;
Brufen Retard is not suitable for children under the age of 12 years;
Like other anti-inflammatory medicines, Brufen Retard may mask signs of infection;
This product belongs to the group of medicines (NSAIDs), which can impair fertility in women. This effect is reversible upon discontinuation of the drug;
Patients who have previously had problems with the gastrointestinal tract, particularly in the elderly, should contact a doctor if you experience abdominal symptoms, especially early in treatment;
Serious skin reactions have been reported very rarely with the use of NSAIDs. Stop taking Brufen Retard and contact your doctor if you develop a rash or changes in the mucous membranes;
In patients with systemic lupus erythematosus and mixed connective tissue disorders there may be an increased risk of aseptic meningitis;
Immediately stop taking Brufen Retard and call your doctor if you develop any of these symptoms (angioedema):
swelling of the face, tongue or throat;
difficulty in swallowing;
hives and difficulty breathing.
Drugs such as Brufen Retard may lead to slightly increased risk of heart attack or stroke. This increased risk is more likely with the use of high doses and prolonged treatment. Do not exceed the recommended dose or duration of treatment;
Consult your doctor or pharmacist about your treatment if you have heart problems, if you have already had a stroke or if you think you have an increased risk of these conditions (for example if you have high blood pressure, diabetes, high cholesterol or if you smoke) ;
Do not take Brufen if pregnant. First consult your doctor;
It is recommended during illness chickenpox should avoid use of this product;
Brufen may lead to a decrease in white blood cells and your resistance to infection may be low. If you have an infection with symptoms such as fever and serious deterioration of your general condition, or fever with local infection symptoms such as sore throat / pharynx / mouth or urinary problems you should contact your doctor immediately. We need to do a blood test to check possible low white blood cells (agranulocytosis). It is important to inform your doctor of medicine you take.
Taking other medicines:
Do not use different types of painkillers at the same time unless directed by a doctor.
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Brufen Retard may affect or be affected by other medicines, including medicines to treat:
tumors and immune system disorders (methotrexate);
manic-depressive illness (lithium);
irregular heartbeat (digoxin);
pain (acetylsalicylic acid);
thrombosis (e.g., dicoumarol, warfarin, ticlopidine);
depression (drugs called selective reuptake inhibitors of serotonin);
high blood pressure (such as beta blockers, diuretics, angiotensin converting enzyme inhibitors, angiotensin-II-inhibitors);
Fungal infections (antifungal, especially voriconazole and fluconazole);
infection by human immunodeficiency virus (HIV) (zidovudine).
Because of these interactions, the doctor should know about all the medicines you are taking.
Use of Brufen Retard with food and drink
Brufen Retard can be taken with food and drinks.
Pregnancy and lactation
Ask your doctor or pharmacist for advice before taking any medicine.
Pregnant women should not use Brufen Retard during the last three months of pregnancy. The use of Brufen Retard should be avoided by women who are planning pregnancy or are pregnant. Treatment at any time during pregnancy should be applied only if prescribed by a doctor.
Ibuprofen passes into breast milk. Therefore, its use is not recommended during lactation. Consult a doctor if the use of Brufen Retard is necessary during lactation.
The use of Brufen Retard can affect fertility. Its use is not recommended while trying to get pregnant or during investigation of infertility.
Driving and using machines
Brufen Retard may worsen reactions in some people, such as side effects such as visual disturbances, drowsiness and dizziness. This must be considered in case of requiring an increased concentration, for example while driving.
3 HOW TO TAKE Brufen Retard
Always take Brufen Retard exactly as you told your doctor. If you are unsure, check with your doctor or pharmacist.
The recommended dose for adults and adolescents over 12 years: 2 tablets every night (possibly one tablet in the morning and 2 tablets in the evening). The maximum daily dose is 2,400 mg. To prevent a burning sensation in the mouth and throat, the tablets should be swallowed whole with at least half a glass of water.
If you have severe liver or kidney disease or if you are elderly, your doctor will tell you the exact dose of acceptance, which will be the lowest possible.
Brufen Retard is not suitable for children 12 years sex.
If you take more than you should Brufen Retard
If you take Brufen Retard more than you should, or children adopted drug accidentally, immediately contact your doctor and hospital to get an opinion on the risk and for advice on the action to be taken.
Symptoms may include nausea, stomach pain, vomiting (may be bloody with threads), headache, TINNITUS, confusion, and rapid eye movements. At high doses, have been reported loss of consciousness, convulsions (mainly in children), weakness and dizziness, blood in urine, feeling cold in the body and breathing problems.
If you forget to take Brufen Retard
Do not take a double dose to recover the missed dose.
If you have further questions on the use of this product, ask your doctor or pharmacist.
4 POSSIBLE SIDE EFFECTS
As with all medications, Brufen Retard have side effects, although not everyone gets them.
Common (affects 1 to 10 users in 100):
Gastrointestinal side effects (loss of appetite, burning diarrhea, nausea, vomiting, abdominal pain, bloating, constipation, black stools, bleeding from the stomach and intestines);
Uncommon (affects 1 to 10 users in 1,000): Runny nose, insomnia, anxiety, loss of hearing; shortness of breath, bronchospasm, asthma or worsening asthma; gastric ulcer, inflammation of the stomach lining; hives, itching, small abrasions on the skin and mucous membranes, angioedema (for symptoms see section 2 special care with Brufen Retard), photosensitivity; impaired renal function, blood dyscrasias including agranulocytosis, drowsiness, tingling.
Rare (affects 2 to 10 users in 10,000): nonbacterial meningitis, allergic reactions, depression, confusion, impaired vision, TINNITUS (ringing in the ears), impaired liver function, water retention in the body.
Very rare (affects less than 1 in 10,000 users):
Inflammation of the pancreas, liver failure, changes in skin and mucous membranes such as epidermal necrolysis and / or erythema multiforme.
Colitis and Crohn's disease.
Please note that Brufen Retard may prolong bleeding time.
There are no reported cases of hypertension and heart failure, and deterioration of ulcers of the colon and Crohn's disease under treatment with analgesics (NSAIDs).
In cases of chicken pox can have especially serious infections of the skin.
Drugs such as Brufen may lead to a slightly increased risk of heart attack or stroke.
If any of these side effects become serious, or you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
5 HOW TO STORE Brufen Retard
Store in a place out of sight and reach of children,
Blister: Store at temperatures below 25 C. Store in the original package to protect from moisture.
Plastic bottle: Do not store above 25 C. Keep the bottle tightly closed in order to protect from moisture.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6 FURTHER INFORMATION
Contents Brufen Retard
One tablet contains 800 mg of ibuprofen.
The active substance is ibuprofen.
Other adjuvants are xanthan gum, povidone, stearic acid, colloidal silicon dioxide, talc, hypromellose, titanium dioxide (E 171).
Brufen Retard looks like and contents of container
White oval, film-coated prolonged-release tablets.
30 tablets are placed in blisters.
100 tablets in plastic bottles.
Not all pack sizes may be marketed.