BUSKOPAN 10 mg. 20 tablets
BUSKOPAN 10 mg. 20 tablets
One coated tablet contains 10 mg Butylscopolamine bromide (butylscopolamin bromide)
Butylscopolamin bromide is extracted from the flowers and leaves of the plant Duboisia myoporoides, whose therapeutic action is rooted in the knowledge of the ancient cultures of South America. Boehringer Ingelheim maintains its resources for the production of selected products from its own plantations in Brazil and Australia. Cultivation and processing plants is done according to the most precise technological and environmental standards lead to the synthesis of high-quality pharmaceutical product passed the test of time.
As a quaternary ammonium compound, butylscopolamin bromide has a direct spasmolytic effect on the smooth muscle of the gastrointestinal complex, biliary tract and urogenital tract.
After oral administration, the active ingredient selectively blocking the muscarinic receptors of the visceral muscle neutralize the action of acetylcholine and relaxes smooth muscle spasm. It appears further selective ganglionic blocking effect by binding to nicotinic receptors in visceral stena.Ne crosses the blood brain barrier and has no systemic effect on the central nervous system.
Calcium hydrogen phosphate, corn starch, soluble starch, colloidal silicon dioxide, tartaric acid, stearic, palmitic acid, polyvinylpyrrolidone, sucrose, talc, gum arabic, titanium oxide, polyethylene glycol 6000, carnauba wax, bleached wax.
BUSKOPAN has antispasmodic action on the smooth muscle of the gastrointestinal, biliary and genitourinary tract. As a quaternary ammonium derivative Butylscopolamine bromide does not penetrate into the central nervous system. Therefore, no observed adverse effects on the central nervous system. Peripheral antivagusovo action occurs as the result of the ganglionic blocking action on the wall of the internal organ, and as a result of the antimuscarinic activity.
Spasm of the gastrointestinal tract, spasms and dyskinesia of the biliary system, spasms of genito-urinary tract.
Dosage and method of administration
Unless otherwise directed by a doctor following dosages are recommended:
Adults and children over 6 years: 3-5 times daily 1-2 coated tablets. Coated tablets should be swallowed whole with the corresponding liquid.
BUSKOPAN can enhance protivovagusovoto action of some antidepressants, antihistamines, gvinidini, amantadine and disopyramide.
Concomitant treatment with dopamine antagonists such as metoclopramide may lead to a weakening of the action of both drugs on the gastrointestinal tract. Resulting from the use of beta-agonists (for asthma) palpitations may be enhanced by BUSKOPAN.
Pregnancy and lactation
Extensive observations show no evidence of ill effects during pregnancy in humans. Preclinical studies in rats and rabbits showed no embryotoxic or oncogenesis action. However, to be respected usual precautions regarding the use of drugs during pregnancy, especially during the first three months. Safety during lactation has not been established. There were no reported side effects in the newborn.
May arise anticholinergic side effects, including skin manifestations, palpitations and possibly urinary retention, but they are mostly mild and transient. Very rarely hypersensitivity reactions, especially skin reactions. Observed anaphylaxis with episodes of dyspnea and shock.
In case of overdose can occur anticholinergic effects.
If necessary, to be appointed medicines called parasympathomimetics. In patients with increased intraocular pressure (glaucoma) should urgently seek advice from an ophthalmologist. Cardiovascular complications should be treated according to the usual therapeutic principles. In case of respiratory paralysis is taken intubation and mechanical ventilation. In urinary retention may need catheterization. If necessary, take measures to support vital functions.
Keep out of reach of children.
Do not apply after the expiry date stated on the packaging.
Carton containing 20 coated tablets.