BIBLOC 10 mg. 30 tablets

BIBLOC 10 mg. 30 tablets
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Bibloc belongs to a group of medicines, called beta-blockers. They protect the heart from excessive activity. 

BIBLOC 10 mg. 30 tablets

 
 
What is Bibloc and what it is used
Bibloc belongs to a group of medicines, called beta-blockers. They protect the heart from excessive activity.

Bibloc administered for the treatment of:
high blood pressure;
angina (heart pain);
Heart failure causes breathlessness on exertion and fluid retention Bibloc can be used as adjunctive therapy to other medications to treat heart failure.

2 What you should know before taking Bibloc
Do not take Bibloc
if you are allergic to bisoprololov fumarate or any of the other ingredients of this medicine (listed in Section 6);
if you have cardiogenic shock, severe heart condition causing rapid, weak pulse; low blood pressure, cold, moist skin; weakness or fainting;
If you have ever suffered from severe wheezing or severe asthma as they can affect your breathing;
if you have a slow heart rate (less than 60 beats per minute). Ask your doctor if you are unsure;
if you have very low blood pressure;
if you have severe circulation problems (which can cause the fingers or toes to tingle or you can turn white or bruising);
if you have certain serious heart rhythm problems;
if you have new onset heart failure or heart failure, which is not stabilized and require hospitalization;
if you have a condition in which there is an accumulation of excessive amounts of acid in the body known as metabolic acidosis. Your doctor can give you advice;
if you have a tumor of the adrenal gland, known as pheochromocytoma, which is not cured.
Tell your doctor if you are unsure about any of the above.

Warnings and Precautions
Talk to your doctor before taking Bibloc:
if you suffer from wheezing or difficulty breathing (asthma). It is co-administration of bronchodilator therapy. May need a higher dose beta2-mimetic;
if you have diabetes. The tablets can mask the symptoms of low blood sugar (such as increased heart rate, palpitations or sweating);
If you are fasting (not taking oily food);
if you are being treated for hypersensitivity (allergic). Bibloc may increase hypersensitivity to substances you are allergic to and increase the severity of hypersensitivity reactions. Treatment with adrenaline then can not produce the desired result. May need a higher dose of adrenaline (epinephrine);
with I-st degree heart block (conduction disorder in the heart);
if you suffer from angina of Prinzmetal, which is a type of chest pain caused by spasm of the coronary arteries that supply blood to the heart muscle;
if you have any circulation problems in the extremities - hands and feet;
in case of operation requiring use of anesthetic: if consulted a doctor or dentist visit a hospital for surgery requiring use of anesthetic, tell them about the medicines you are taking;
in combination with calcium channel blockers such as verapamil, and diltiazem. Concomitant use is not recommended, see also section "Other medicines and Bibloc"
if you suffer (or have suffered) from psoriasis (a recurrent skin disorder involving peeling and dry skin rash);
if you have pheochromocytoma (adrenal tumor). You will need your doctor to cure it before you prescribe Bibloc;
if you have thyroid problems. Tablets can mask the symptoms of overactive thyroid gland.
There is no therapeutic experience in the treatment of heart failure in patients with Bibloc with the following diseases and conditions:
diabetes treated with insulin (Type I);
severe kidney disease;
severe liver disease;
certain heart diseases;
heart attack in the previous three months.
Treatment of heart failure with Bibloc requires regular monitoring by a doctor. It is absolutely necessary, especially at the beginning and termination of treatment.
Bibloc treatment should not be stopped abruptly, except for compelling reasons.
In patients with hypertension or angina pectoris with concomitant heart failure treatment should not be stopped suddenly. The dose should be reduced slowly being reduced to half within one week.
Check with your doctor if any of the above warning applies to you or applied to you in the past.

Other medicines and Bibloc
Tell your doctor or pharmacist if you are taking, have recently taken or might take other medicines. This includes medicines obtained without a prescription. Some drugs can not be used simultaneously, and other drugs requiring specific adaptations (dose, for example).

Always tell your doctor if you use or receive any of the following medicines in addition to Bibloc:
Drugs to control blood pressure or medicines for heart problems (such as amiodarone, amlodipine, clonidine, digitalis, diltiazem, disopyramide, felodipine, flecainide, lidocaine, methyldopa, moxonidine, phenytoin, propafenone, quinidine, rilmenidine, verapamil);
Sedatives and drugs to treat psychosis (mental illness) eg. barbiturates (also used for epilepsy), phenothiazines (also used in vomiting and nausea);
Medicines for depression eg. tricyclic antidepressants, MAO-A inhibitors;
Drugs used for anesthesia during surgery (see. Too "Warnings and Precautions");
certain analgesics (e.g. aspirin, diclofenac, indomethacin, ibuprofen, naproxen);
Medicines for asthma, blocked nose or certain eye disorders such as glaucoma (increased pressure in the eye) or dilation (widening) of the pupil;
certain drugs for the treatment of shock (eg. epinephrine, dobutamine, norepinephrine);
mefhlohin, a medicament for treatment of malaria;
antibiotic rifampicin;
ergot derivatives in migraine.
All of these drugs and Bibloc may affect blood pressure and / or cardiac function.
insulin or other medicines for diabetes. Can enhance the effect of lowering blood sugar. Can mask the symptoms of low blood sugar.
Bibloc with food and drink
Bibloc can be taken with or without food or tablets should be swallowed whole with a little water.
Bibloc alcohol
Dizziness, which can be caused by Bibloc may deteriorate if you drink alcohol. If this happens, you should avoid drinking alcohol.

Pregnancy and lactation
If you are pregnant or breast-feeding, you may be pregnant or planning to become pregnant, talk to your doctor before taking this medicine. Bibloc can be harmful to the pregnancy and / or the unborn child. There is a greater likelihood of premature birth, miscarriage, low blood sugar and decreased heart rate of the child. Growth of the child may also be affected. Therefore, bisoprolol must not be administered during pregnancy.
It is not known whether bisoprolol is excreted in breast milk and therefore is not recommended during lactation.

Driving and using machines
No studies on the effects on ability to drive and use machines. These tablets may make you feel tired, sleepy or dizzy.
If you have these side effects, do not drive or operate machinery. You must be aware of the possibility of these side effects, especially at the beginning of treatment, a change in medication and in concomitant use with alcohol.

Bibloc contains lactose
If your doctor tells you that you have an intolerance to some sugars, contact before taking this medicine.

3 How to take Bibloc
Always take this medicine exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist.
Your doctor will tell you how many tablets to take. You should take Bibloc morning before or after breakfast. Swallow / s with a little water and do not chew or crush.

High blood pressure / angina pectoris:
adults
The dose is determined individually.
The recommended starting dose is 5 mg once daily.
The usual dose for adults and 10 mg once daily. Your doctor may decide to increase or decrease the dose.
The maximum dose is 20 mg once daily.

Severe renal or hepatic function
If you suffer from severe renal or hepatic function, the maximum dose is 10 mg daily.

Elderly
Normally it is not necessary to adjust the dose. Your doctor will start with the lowest possible dose.

Heart failure (reduced pumping force of the heart)
Before you start taking Bibloc you are already taking an ACE inhibitor, a diuretic or cardiac glycoside (drugs for the heart / blood pressure).
The dose will be increased gradually until reaching the right dose for you:
1,25 mg once daily for 1 week. If well tolerated, the dose may be increased to:
2,5 mg once daily for the next week. If well tolerated, the dose may be increased to:
3,75 mg once daily for the next week. If well tolerated, the dose may be increased to:
5 mg once daily for the next 4 weeks. If well tolerated, the dose may be increased to:
7,5 mg once daily for the next 4 weeks. If well tolerated, the dose may be increased to:
10 mg once daily as a maintenance dose.
Maximum dose is once daily 10 mg.
The doctor will determine the optimal dose for the crowd you based on possible side effects.
After the first dose of 1,25 mg doctor will check your blood pressure, heart rate, cardiac dysfunction.

Violations of function of liver or kidney
The doctor will be more careful when increasing the dose.

Elderly
Normally it is not necessary to adjust the dose.

If you notice that the effect of Bibloc is too strong or not strong enough, please consult your doctor or pharmacist.

To break the tablets
Place the tablet on a hard, flat surface scored up.
Click thumb and middle Tablet tablet will break into two halves. Click thumb middle of each half and get quarters.

Duration of treatment
Bibloc will normally be administered long-term.

Use in children and adolescents
No experience with Bibloc in children and adolescents, therefore its use in children is not recommended.

If you take more than you should Bibloc
If you take more than the prescribed dose, inform your doctor / pharmacist. Take the remaining tablets or this leaflet with you to allow the medical team to see what you have taken. Symptoms of overdose may include drowsiness, dizziness, fatigue, shortness of breath and / or wheezing. You also have a slow heart rate, low blood pressure, insufficient action of the heart and low blood sugar (which can include a feeling of hunger, sweating and palpitations).

If you forget to take Bibloc
Do not take a double dose to make up for a missed dose. Take your usual dose as soon as you remember and then continue with the usual dose the next day.

If you stop taking Bibloc
Treatment with Bibloc should not be stopped abruptly. If you suddenly stop taking this medicine your condition may worsen. Instead, treatment should be discontinued gradually over several weeks under the advice of your doctor.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4 Possible side effects
As with all medications, Bibloc can cause side effects, although not everyone gets them.

Side effects that may occur are:
Very common - can occur in more than 1 patient in 10:
bradycardia (slow heart rate). In the treatment of hypertension or angina pectoris adverse reaction occurs infrequently.
Common - can occur in 1 to 10 out of 100 patients:
fatigue. In the treatment of hypertension or angina pectoris adverse reaction occurs infrequently;
dizziness, fatigue, and headache (especially at the beginning of treatment in patients with hypertension and angina pectoris, symptoms are generally mild and often disappear within 1-2 weeks);
feeling cold or numbness of the extremities (fingers or toes, ears and nose); more often experience painful cramps in the legs when walking;
worsening of pre-existing cardiac insufficiency. In the treatment of hypertension or angina pectoris adverse reaction occurs infrequently;
very low blood pressure (hypotension), especially in patients with heart failure;
nausea, vomiting;
diarrhea;
constipation.
Uncommon - can occur in 1 to 10 out of 1000 patients:
fatigue. In the treatment of heart failure this side effect occurs frequently;
drop in blood pressure upon standing, which can cause dizziness, dizziness or fainting;
sleep disorders;
depression;
slow heartbeat. In the treatment of heart failure adverse reaction occurs very often;
irregular heartbeat;
worsening of pre-existing cardiac insufficiency. In the treatment of heart failure this side effect occurs frequently;
patients with a history of asthma or breathing problems may have difficulty in breathing;
muscle weakness and muscle cramps.
Rare - may occur in 1 to 10 per 10 000 patient:
nightmares;
hallucinations (false perceptions of something);
syncope;
hearing loss;
inflammation of the lining of the nose, causing fever with inflammation;
allergic reactions (such as itching, flushed appearance, rash);
dry eye due to reduced tear production (which can be very disturbing if you wear contact lenses);
inflammation of the liver (hepatitis), causing abdominal pain, loss of appetite and sometimes yellowing of the whites of the eyes and skin and dark urine;
decreased sexual ability (breach of potency);
elevated levels of blood lipids (triglycerides) and liver enzymes.
Very rare - can occur in less than 1 in 10,000 patients:
chest pain;
deterioration of the skin condition psoriasis or causing similar dry, scaly rash and hair loss;
itching or redness of the eyes (conjunctivitis).
If you get any side effects, tell your doctor or pharmacist. This includes all listed in this leaflet.

5 How to store Bibloc
Keep out of reach of children.
Do not use this medicine after the expiry date stated on the carton and on the blister after "EXP". The first two digits indicate the month, the last year figures. The expiry date refers to the last day of that month.

blisters:
This medicinal product does not require any special storage conditions.

HDPE bottles:
This medicinal product does not require any special storage conditions.

Do not dispose of medications in drains. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6 Package Contents and more information
Contents Bibloc
The active substance is 10 mg bisoprololov fumarate.

Other ingredients are:
calcium hydrogen phosphate anhydrous;
microcrystalline cellulose;
corn starch, pre-gelatinized;
croscarmellose sodium;
silica colloidal anhydrous;
magnesium stearate;
lactose monohydrate;
hypromellose;
macrogol 4000;
titanium dioxide (E171);
yellow iron oxide (E172);
red iron oxide (E172).
 
 
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