Avelox . 400 mg. 7 tablets
Avelox . 400 mg. 7 tablets
What is AVELOX 400 mg film-coated tablets and what are they used?
AVELOX 400 mg tablets contain broad-spectrum antibiotic, which means it kills a wide range of pathogenic microorganisms. Moxifloxacin, the active substance of AVELOX 400 mg tablets belongs to the quinolone group.
AVELOX 400 mg film-coated tablets are used to treat the following bacterial infections (provided that they are caused by organisms susceptible to moxifloxacin):
Exacerbations of Chronic Bronchitis
Acute sinusitis (inflammation of the paranasal sinuses) and infections of skin and soft tissues.
What you should know before taking AVELOX 400 mg tablets?
You should not use A VELOX 400 mg tablets if you are allergic to moxifloxacin, other quinolones or any other ingredients if you have had inflammation or tendon damage after treatment with these substances (quinolones), if you have a congenital or documented condition associated with certain disorders of the electrocardiogram (ECG, QT interval) if you suffer from salt violations, especially if you have low concentrations of K + in your blood (hypokalemia), if you have a clinically significant bradycardia (slow heart rate) if Your doctor has diagnosed clinically relevant heart failure with reduced left ventricular ejection fraction (weak heart) if you have a history of symptomatic cardiac arrhythmias. A VELOX 400 mg tablets should not be used with other drugs that cause certain ECG abnormalities (QT prolongation). Suffer from impaired liver function (Child-Pugh class C) or elevated transaminases> 5 times the upper granitsa.Bremennite normal women, nursing mothers, children and adolescents should not take A VELOX 400 mg tablets.
Particular attention is necessary when used AVELOX400 mg film-coated tablets in the following cases:
if you have ever had seizures, you should consult your doctor before taking A VELOX 400 mg film-coated tablets
if you have a visual impairment, affecting your eyes, you should consult an ophthalmologist immediately.
Inflammation and torn ligaments may occur during therapy with quinolones, including moxifloxacin (active ingredient AVELOX 400 mg film-coated tablets), especially in elderly patients or patients receiving concomitant therapy with anti-inflammatory medications (corticosteroids). At the first sign of pain or swelling should stop taking AVELOX 400 mg film-coated tablets, put limb and consult your doctor immediately to further lechenie.Moxifloxacin cause certain disturbances on the electrocardiogram (ECG) known as prolongation of the QT interval in some patients.
Although the effect is not very pronounced, A VELOX 400 mg film-coated tablets should be used with caution if you are taking other medicines that can reduce potassium level in the blood. Patients at increased risk of arrhythmias (eg acute myocardial ischemia) should be careful when taking Avelox. QT prolongation may increase the risk of certain types of cardiac arrhythmia (ventricular arrhythmias, including torsades de pointes). As the degree of QT interval is increased in proportion to dose, the recommended dose should not be exceeded. Consult your doctor if in doubt. If symptoms of cardiac arrhythmia occur during treatment with A VELOX stop treatment and consult your doctor. If you have impaired liver, talk to your doctor to make ??????????.????????????????? antibiotics including moxifloxacin can cause severe diarrhea (pseudomembranous colitis). In this situation you should immediately take appropriate therapeutic measures. In case of severe diarrhea occurring during or after antibiotic use, please consult your doctor. Do not take drugs that suppress gastric peristaltika.Ako for you or your family members is established glucose-B-phosphate dehodrogenazen deficiency (congenital or acquired metabolic disorder), please tell your doctor before taking AVELOX 400 mg coated tabletki.Protivopolozhno other quinolones, moxifloxacin does not represent a significant risk of inducing photosensitivity study. However, during treatment with AVELOX 400 mg film-coated tablets, you should avoid Tryavna UV irradiation (alpine sun, solarium) and not exposed to excessive and / or highly slantse.Reaktsiite Hypersensitivity or allergic reactions (eg rash ) may occur after the first administration of quinolones. In extremely rare cases can be severe Cutting fast allergic reactions ranging to life-threatening shock. In these cases, the use of moxifloxacin should immediately be stopped immediately and should start treatment (eg treatment for shock).
You should always check with your doctor or pharmacist before taking lekarstvata.Da not take AVELOX 400 mg tablets if you are pregnant. KarmeneVie should always consult with your doctor or pharmacist before taking lekarstvata.Da not take A VELOX 400 mg tablets if you are pregnant. Driving and using mashiniAko you sleepy after taking A VELOX 400 mg film-coated tablets, avoid driving or operating mashini.Vazhna information for certain other ingredients in AVELOX 400 mg tablets: AVELOX 400 mg film-coated tablets containing lactose. Therefore, you should not take this medication without consulting your doctor know if you have glucose intolerance.
Interactions with other drugs
Please tell your doctor or pharmacist if you are taking / using other medicines or have taken / used other drugs recently, even if they are not prescription medications.
Please note the following when taking other medicines:
A VELOX can influence heart rate (QT interval). This effect can be increased in case of concomitant administration of the following drugs: Class 1 antiarrhythmic drugs (eg quinidine, hydroquinidine, disopyramide) and class III (eg amiodarone, sotalol, dofetilide, ibutilide) antiarrhythmics (medicines to treat cardiac arrhythmias ), antipsychotics (medications to treat mental disorders such as phenothiazines, pimozide, sertindole, haloperidol, sultopride), tricyclic antidepressants, certain anti-inflammatory (sparfloxacin, intravenous erythromycin, pentamidine, antimalarials, particularly halofantrine), certain drugs used to treat allergic symptoms (terfenadine, astemizole, mizolastine) and others (cisapride, a medicine used to stimulate peristalsis, intravenous vincamine, bepredil, diphemanil). Moxifloxacin should therefore not be used in conjunction with these products.
A range of about six hours must elapse between taking medicines containing certain metals (bivalent or trivalent cations) and taking AVELOX 400 mg tablets. This includes antacids that contain magnesium or aluminum (medicines used to prevent hyperacidity of the stomach), certain anti-viral tablets containing didanosine, sucralfate and medicines containing felyazo or zinc.
Concomitant administration of AVELOX 400 mg film-coated tablets and activated carbon significantly reduced the absorption of moxifloxacin in the body. Therefore, concomitant use of these two products is not recommended.
In a study conducted in healthy volunteers, coadministration of AVELOX 400 mg film-coated tablets with digoxin (a medicine used to treat heart failure) results in an approximate 30% increase in peak plasma concentrations of digoxin. No special precautions for concomitant A VELOX and digoxin.
In studies conducted in diabetic patients, concomitant administration of AVELOX 400 mg film-coated tablets, glibenclamide (a medicine used to treat diabetes) resulted in a 21% decrease in peak plasma concentrations of glibenclamide. Blood glucose and insulin levels were not affected.
Increased anticoagulant effect was reported in a number of cases where patients are treated concomitantly with antibiotics and anticoagulants. However, it is reported clinically significant interaction between moxifloxacin and warfarin (anticoagulant). The values of coagulation parameters can be monitored more frequently as a precautionary measure anticoagulant dosage adjusted as necessary.
No interactions when AVELOX 400 mg tablets are taken concomitantly with medicines containing the following drugs: ranitidine (used to treat peptic ulcers), probenecid (used to reduce serum uric acid), oral contraceptives (pills birth control ), calcium supplements, morphine (narcotic analgesic), theophylline (used for asthma) or itraconazole (used to treat fungal infections).
When taking AVELOX 400 mg film-coated tablets with food and drink
The effects of AVELOX 400 mg film-coated tablets are not affected by food, including milk produkti.3. How should I take AVELOX 400 mg tablets? A VELOX 400 mg film-coated tablets are always taken in accordance with the instructions of your doctor. Please consult your doctor or pharmacist if you are not sure how to take this lekarstvo.A VELOX 400 mg tablets to be taken orally. Unless prescribed otherwise by your doctor, the usual dose is: Adults take 1 tablet. AVELOX 400 mg tablets once dnevno.Ne need dose adjustment in elderly patients, a patient with low body weight, patients with mild to moderate renal impairment or patients dializa.Nyama data for use in patients with impaired hepatic function . Please consult your doctor or pharmacist if you have noticed that the effects of AVELOX 400 mg film-coated tablets are too strong or too slabi.Filmiranata tablet swallowed whole with plenty of fluid. You should not take A VELOX 400 mg tablets during meals.
Unless prescribed otherwise by your doctor AVELOX 400 mg tablets to be taken with the following durations:
inflammation of the lower pulmonary tract (bronchitis): 5 to 10 days
pneumonia (community acquired): 10 days
Acute sinusitis (inflammation of the paranasal sinuses) 7 days
Skin infections 7 days
You must complete the full course of treatment with AVELOX 400 mg film-coated tablets, as the infection may not be completely cured.
If you have a large amount of AVELOX 400 mg film-coated tablets predlgame you:
The recommended dose of 400 mg once daily should not be exceeded. If you accidentally take more than one tablet a day, you should continue your treatment the next day, as prescribed. The concomitant administration of activated charcoal and 400 mg moxifloxacin reduced bioavailability of moxifloxacin by more than 80%. Early administration of activated charcoal may be useful to protect against very high levels of moxifloxacin in the blood if taken an overdose of tablets moxifloxacin.
If you forget to take A VELOX 400 mg film-coated tablets:
You should take your next tablet immediately and continue your treatment with one tablet dnevno.Da not take a double dose to correct missed a single dose. The effects of discontinuation of A VELOX 400 mg tablets: If taking AVELOX 400 mg tablets stop your symptoms may get worse. Please consult your doctor if you should stop taking A VELOX 400 mg tablets before the end of the treatment course.
What are possible side effects?
Like all drugs, AVELOX 400 mg tablets can have side effects.
Hyperglycemia (elevated blood sugar), hyperlipidemia (elevated lipid levels), elevated prothrombin levels / low INR (specific coagulation parameters), jaundice (jaundice caused primarily by obstruction of bile) in connection with altered chernodrochna function, elevated levels of specific liver enzyme (LDH), elevated creatinine or ureya.Vaz on clinical experience AVELOX400 mg tablets until it is not possible to give a definitive assessment of the possible side effects after taking AVELOX. Isolated cases of the following adverse reactions have been reported during treatment with other fluoroquinolones, and they can also occur during treatment with AVELOX400 mg tablets: Transient loss of vision, balance problems including ataxia (influence on the ability to perform movements ) hypernatraemia (elevated blood sodium), hypercalcemia (elevated levels of calcium in the blood), neutropenia (low levels of certain white blood cells), hemolysis (increased breakdown of red blood cells). Inform your doctor or pharmacist if you notice any side effects not listed in this leaflet.
How should I store AVELOX tablets?
Keep out of reach of detsa.Da stored at temperatures not exceeding 25 ° C. Tablets can be stored in their original opakovka.Filmiranite tablets can be stored in the original container next to their upotreba.Srokat life of this product is printed on the label on the packaging blister ivarhu stripove.Da not use after the expiration date.
Active substance: moxifloxacin hydrochloride
film-coated tablet contains 400 mg moxifloxacin form of 436,8 mg moxifloxacin hydrochloride as a pharmaceutical drug.
List of excipients
Krospomeloza sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, hypromellose, macrogol 4000, titanium dioxide (E171) and iron oxide (E172). AVELOX400 mg film-coated tablets are available in packs containing 5, 7 or 10 tablets and hospital packages.
Tablets are pale red and marked with "M400" on one side and "Bayer" strana.Filmiranite the other tablets are packaged in polypropylene / blister strips and come in cartons.