Ampicillin. 1000 mg. 1 vial
Ampicillin. 1000 mg. 1 vial
In Ampicillin 500 mg powder for injection : Ampicillin sodium 531 mg.
In Ampicillin 1 g powder for solution for injection : Ampicillin sodium 1063 mg.
Ampicillin is an antimicrobial from the penicillin group . Upon treatment with ampicillin destroyed microorganisms which cause various types of infections .
Ampicillin powder for injection is used to treat serious infections caused by susceptible micro-organisms : infections of the respiratory system ; some infections in the teeth and gums ; otitis media ; infections of the genitourinary system; gonorrhea gastrointestinal infections : typhoid and paratyphoid ; infections of the biliary tract ; inflammation of the meninges - meningitis , inflammation of the lining of the heart and the valve - endocarditis , listeriosis , and before and after an operation.
Ampicillin is not applicable in cases of hypersensitivity to ampicillin , penicillin or other cephalosporin antibiotics .
Adoption of ampicillin is usually well tolerated . Sometimes possible gastrointestinal disorders - nausea , vomiting , irritation of the oral cavity , caused by the fungus, abdominal pain, diarrhea , dark yellow or brown urine , pain, swelling and irritation of the injection site , fever , convulsions . Possible allergic reactions - skin rashes , urticaria , flushing , fever , swelling of the face and / or eyelids, bronchospasm .
With prolonged treatment often may appear anemia , thrombocytopenia (low platelets - platelets) , leucopenia (low white blood cells) , which usually resolve after treatment .
If you notice side effects , even those not included in this information or are not sure about the effect of ampicillin , tell your doctor.
As a result of the application of ampicillin possible false positive reaction for glucose in the urine. There may be a transient change and certain enzymes in the blood .
In case of overdose can occur seizures. In patients with renal impairment may be seen some of these side effects . There is no means to combat the poisoning , the drug is stopped and apply treatment of symptoms.
This medicine is an antibiotic , so it must be applied at regular intervals to observe the full course of treatment prescribed by your doctor.
Should not be discontinued its use at the first signs of improvement. There may be mild forms of allergy - rashes , fever, other skin reactions. The preparation is used with caution in renal failure, which may require changes in the intervals of drug administration .
Ampicillin is not recommended in infectious mononucleosis ( glandular fever so called ) or allergy ( hay fever, asthma , urticaria) , so the doctor should be informed of the presence of such suffering.
In patients with a restriction of the sodium in the diet should be given to the quantitative content of sodium ( about 62 mg / g) in the preparation. If severe and persistent diarrhea necessary inform your doctor as use of antibiotics such as ampicillin inhibit normal growing microorganisms in the intestine and can lead to severe life-threatening condition known as pseudomembranous colitis.
During prolonged treatment with ampicillin can lead to fungal infections , which require appropriate treatment.
In patients with suspected gonorrhea necessary laboratory testing to exclude disease of syphilis. After completion of treatment should be carried out serological testing.
Let your doctor know if you are taking any medications , as some of them may be inappropriate when used together with ampicillin. If necessary your doctor may combine with other antibiotics ampicillin .
Co-administration of ampicillin with contraceptives _ may reduce their effect. High doses of ampicillin can reduce the effects of atenolol, therefore atenolol should precede that of ampicillin.
The administration of ampicillin and allopurinol can cause skin rashes , particularly in sensitive patients.
Co-administration of ampicillin probenecid prolongs renal elimination of the composition.
DOSAGE AND METHOD OF ADMINISTRATION
Ampicillin is only available with a doctor's prescription !
Ampicillin powder for injection is injected in a muscle or a vein , or is inserted into a vein by infusion. Must be applied at regular intervals . Dosage and duration of treatment is determined only by the physician .
The usual doses are:
Adults - 500 mg every 6 hours , the daily dose is 2-6 g, but can reach 6d .
In severe infections can be administered 150-300 mg/kg/24ch in equal doses every 6 hours as a short infusion .
For children - 50-100 mg / kg per day, intravenously or intramuscularly every 6 hours ; In severe infections - 100-400 mg/kg/24 h in 6 hours. For newborns to 7 days: 50 mg/kg/24 hours intramuscularly or intravenously , divided into equal doses every 12 hours ; meningitis : 75 mg/kg/24chasa intravenously in equal doses every 8 hours .
For infants and older than 7 days : 75mg/kg/24ch , intramuscularly or intravenously every 8 hours; meningitis : 150-200 mg/kg/24ch intravenously , in equal doses every 6 hours .
In patients with renal insufficiency is necessary to adjust the dosage to be determined by your doctor. The duration of treatment can be determined by the attending physician .
Method of preparation:
For intramuscular administration - the contents of the vials of 250 mg, 500 mg and 1 g was added , respectively, 1 , 2, and 4 ml of sterile water for injections. For intravenous administration, - the contents of the vials of 250 mg was added 3 ml, and 500 mg - 5 ml of sterile water for injection ; duration of injection is 3 - 5 minutes , to a vial of 1 g were added 10 ml of sterile water for injection, the duration of the injection was 5 - 10 min
For intermittent intravenous infusion (not recommended continuous infusion ) - prepared by the above-described manner a solution was diluted immediately in 100 ml 0,9% NaCl solution or a 5 % glucose solution . Infusion 30-60 minutes.
Recommended ampicillin solution to apply immediately after preparation.
Do not freeze .
Pregnancy and lactation
The doctor should be informed of the pregnancy. Treatment with amitsilin during gestation is considered to be safe . Small amounts of it pass through breast milk and may cause diarrhea and rash in the infant.
EFFECTS ON THE ABILITY TO DRIVE AND USE MACHINES
Ampicillin no effect on driving and operating machinery.
PHARMACEUTICAL FORM AND CONTENTS
Ampicillin powder for injection 250 mg, 500 mg and 1 g in glass vials.
Ampicillin should be stored out of reach of children! Keep ampicillin capsules dry and protected from direct sunlight areas at temperatures below 25 ° C. Do not use after the expiry date printed on the package .
The shelf life of the formulation of three years !