Amlodipine. 10 mg. 30 tablets
Amlodipine. 10 mg. 30 tablets
WHAT amlodipine alkaloids AND WHAT IT IS USED
Alkaloid amlodipine (amlodipine) belongs to a class of medicines known as calcium channel blockers amlodipine is used for the treatment of high blood pressure (hypertension), and a certain type of chest pain, known as angina (angina pectoris, angina pectoris), a rare form which is Prinzmetal angina or variant. For patients with high blood pressure, act as Alkaloid Amlodipine relaxes blood vessels so that the blood flows more easily through them. In patients with angina Amlodipine Alkaloid improves blood supply to the heart muscle, which thus receives more oxygen and consequently preventing chest pain. Amlodipine Alkaloid not provide instant relief of chest pain angina.
2. DOSAGE AND METHOD OF ADMINISTRATION
Always take Amlodipine alkaloid exactly as your doctor tells you. If you are not sure, ask your doctor or pharmacist. The usual dose is 5 mg once daily. Thereafter, the dose may be increased to 10 mg once a day depending on the individual response. It is best to take Amlodipine Alkaloid at the same time each day to water.
It is important to keep taking Amlodipine alkaloids, unless your doctor tells you otherwise.
Consult your doctor or pediatrician regarding the use of this medicine in children. Special care is required. Alkaloid amlodipine should not be taken by children.
If you take more dose Amlodipine Alkaloid
If you take more than you should, you should immediately contact your doctor. Symptoms of overdose may include severe dizziness, fainting, fast heartbeat.
If you forget to take Amlodipine Alkaloid
If you forget to take your daily dose, continue with the next dose. Do not take a double dose to make up for a missed dose.
If you stop taking Amlodipine Alkaloid
No suspension suddenly taking amlodipine. Consult your doctor or pharmacist about the gradual reduction of the dose.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
Amlodipine is contraindicated in patients with:
Hypersensitivity to amlodipine, dihydropyridine derivatives or to any of the excipients.
Shock, including cardiogenic shock
Heart failure after acute myocardial infarction (during the first 28 days)
Outlet obstruction of the left ventricle (eg high grade aortic stenosis)
Unstable angina pectoris.
Effects of other medicinal products on amlodipine
CYP3A4 inhibitors: A study in elderly patients has shown that diltiazem inhibits the metabolism of amlodipine, probably via CYP3A4, since plasma concentration increases by approximately 50% and the effect of amlodipine is amplified. It can not be ruled out that the auxiliary inhibitors of CYP3A4 (e.g., ketoconazole, itraconazole, ritonavir) increase the plasma concentration of amlodipine, to a greater extent than diltiazem. The combination of amlodipine with CYP3A4 inhibitors requires attention.
CYP3A4 inducers: There is no information available on the effect of CYP3A4 inducers (eg, rifampicin, St John's wort) on amlodipine. Concomitant use may lead to reduced plasma concentrations of amlodipine. The combination of amlodipine with CYP3A4 inducers requires attention.
Effects of amlodipine on other medicinal products
Amlodipine may potentiate the effect of other antihypertensive agents such as beta-adrenoceptor blockers, ACE inhibitors, alpha 1 blockers, and diuretics. In patients with increased risk (for example after myocardial infarction), the combination of calcium channel blockers with beta-adrenoceptor blockers may lead to heart failure, hypotension and to a (new) myocardial infarction.
Use during pregnancy and lactation
Pregnancy Risk Category: C
Lactation It is not known whether amlodipine is excreted in human milk. Similar calcium channel blockers of dihidroperidinov type are excreted in human milk. It is recommended that during treatment with amlodipine to stop nursing.
Effects on ability to drive and use machines
Amlodipine has minor to moderate influence on the ability to drive and use with patients suffering from dizziness, headache, tiredness or nausea, you may be in the ability to respond.
You may experience drowsiness or dizziness. Do not drive, operate machinery, or perform activities requiring mental alertness until you know how amlodipine affects you. To reduce the risk of dizziness, do not get out of bed and stand up suddenly and quickly, especially if you are elderly.
Important information about some of the ingredients of Amlodipine Alkaloid
Amlodipine Alkaloid contains lactose. If your light tells you that you have an intolerance to some sugars, contact your doctor before taking this product.
5. POSSIBLE SIDE EFFECTS
Like all medicines, Amlodipine Alkaloid can cause side effects, although not everybody gets them.
The most common are: headache, edema (swelling of the ankles), rash, fatigue, nausea, flushing, dizziness, swelling or tenderness of the gums, palpitations (irregular or rapid heart rate). The following effects have been seen in some patients, but the relationship to treatment with amlodipine or the condition is unclear: heart attack (myocardial infarction), irregular heartbeat (arrhythmia), and chest pain.
All medicines can cause allergic reactions. Serious allergic reactions are very rare and even more rarely life-threatening. Any sudden wheezing, difficulty breathing swelling of eyelids, face or lips, rash or itching (especially affecting the whole body) should be immediately reported to the doctor. If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
6. HOW TO STORE amlodipine alkaloids
Keep out of reach of children. Do not use Amlodipine Alkaloid after the expiry date stated on the carton (to mark the expiry date used abbreviations). Expiry date refers to the last day of that month.
Do not remove the tablet from the blister advance. This medicine does not require any special storage conditions.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. FURTHER INFORMATION
Amlodipine Alkaloid contents
The active ingredient is amlodipine.
Each tablet of amlodipine 10 mg Alkaloid contains 10 mg amlodipine (as amlodipine besilate 13,869 mg).
The other ingredients are lactose monohydrate; microcrystalline cellulose; magnesium stearate.