Adrenaline ampoule of 1 ml of 0.1%. 10 amp
Adrenaline ampoule of 1 ml of 0.1%. 10 amp
WHAT ADRENALIN AND WHAT IT IS USED
Epinephrine is a synthetic analogue of the hormones adrenaline , secreted by the adrenal gland. It inhibits the release of substances involved in inflammation and allergy. Causes constriction of blood vessels. Increases sharply , but non-continuous blood pressure excites the respiratory center , reduces the tone of smooth muscles of the bronchi and intestines ( slows peristalsis ) causes hyperglycemia ( increased blood sugar) increases the main exchange Adrenaline Sopharma solution for injection is used to treat emergency cases in a hospital setting : anaphylactic shock in treatment of cardiac arrest (heart stopping ) for cardio-pulmonary resuscitation.
Before applying Adrenalin SOPHARMA
You should not apply Adrenaline Sopharma
When epinephrine apply vital evidence contraindication to the use of the product can only be hypersensitive to the active substance or any of the excipients .
In all other cases these contraindications are relative :
- Hyperthyroidism ( overactive thyroid gland ), hypertension (high blood pressure), coronary heart disease (insufficient blood supply to the heart )
- Glaucoma ( increased eye pressure).
Take special care with Adrenaline Sopharma
Warnings are relative , since Adrenaline Sopharma be used in life-threatening situations . Should be used with caution in elderly patients , severe or persistent asthma and emphysema, degenerative diseases of the heart.
Taking other medicines
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Marked hypertension and bradycardia ( slow heart rate) may occur with concomitant administration of adrenaline Sopharma and non-selective beta-blockers ( propranolol ) . Propranolol can suppress bronchodilator action of epinephrine .
Increased risk of cardiac arrhythmia exists in patients treated with digoxin or quinidine following administration of adrenaline Sopharma .
Administration of Epinephrine Sofarma may impede the control of blood glucose levels in diabetic patients of antidiabetic therapy .
Effects of epinephrine potentiation of tricyclic antidepressants ( medicines for depression ) .
General anesthetics, such as halothane , may increase the risk of ventricular arrhythmias and acute pulmonary edema.
Pregnancy and lactation
Epinephrine crosses the placenta and can cause an increase in heart rate and fetal extrasystoles . Sopharma adrenaline should be administered to pregnant after a rigorous assessment of the ratio of benefit to the mother and the risk to the fetus. Excreted in breast milk, but does not reach pharmacologically active concentrations. Can be used in lactating women .
Driving and using machines
Readings in which the Adrenaline Sopharma exclusive opportunity to drive and use machines.
Important information about some of the ingredients of Adrenaline Sopharma
Sodium metabisulphite present in the composition of the injectable solution may cause allergic reactions, including bronchoconstriction, particularly in patients with a history of asthma or allergy.
3 . HOW TO USE Adrenalin
Dose and duration of treatment is determined by your doctor . Sopharma adrenaline injection is administered subcutaneously or intravenously by qualified medical personnel. Prior to intravenous administration, the solution for injection is diluted to a concentration of 1:10,000 with brine .
For the treatment of anaphylactic shock when administered at doses of 0.2 to 0,5 mg, maximum dose of 1 mg. In cardiac arrest - intravenously at 0.5 to 1 mg every 3-5 minutes during resuscitation .
Intravenously at 0,01 mg / kg ( 10 mcg / kg) body weight during resuscitation . In infants up to 1 month in cardiac arrest Adrenaline Sopharma solution for injection is administered intravenously at a dose of 0,01 mg / kg ( 10 mcg / kg) - 0,03 mg / kg ( 30 (mg / kg) of body weight every 3-5 minutes.
4 . POSSIBLE SIDE EFFECTS
Like all medicines, Adrenaline can cause side effects, although not everybody gets them.
The most common adverse reactions to adrenaline Sopharma associated with the cardiovascular system : tachycardia ( heart rate ) , feeling your heartbeat and blood pressure.
Of the nervous system most frequently observed headache , vertigo and / or dizziness, nervousness , feelings of fear , trembling of the limbs (tremor ) . The most frequently observed respiratory disorder is the feeling of shortness of breath ( dyspnea ) .
On the part of the gastrointestinal tract often may occur nausea and vomiting .
Often expressed vasculitis have high blood pressure (hypertension) and a sense of cooling of the extremities . On behalf of the whole body (general ) disorders are transient pallor , malaise .
Can be observed that the level of blood sugar ( hyperglycemia ) and decreased potassium levels in the blood ( hypokalemia ) .
Less frequently observed strong shortness of ventricular contractions ( fibrillation ) and / or heart failure , abnormal heart rhythms ( arrhythmia) , tightness and pain in the chest (angina) , cerebral hemorrhage due to sharp increases in blood pressure , widening of pupils ( mydriasis ), pulmonary edema ( sudden difficulty in breathing due to cardiovascular disorders and fluid accumulation in the lungs ), urinary retention and difficulty in urination , increased acidity of the blood ( metabolic acidosis) . Rarely hypertensive crises and changes in the skin, mucous membranes, and kidneys.
If any of the side effects gets serious , or you notice other effects not listed in this leaflet , please tell your doctor.
Symptoms, most commonly pale mucous membranes and skin , trembling of the limbs , rapid heart beat , dizziness, cardiac arrhythmias, ventricular fibrillation in passing , a rapid increase in blood pressure , reaching down to hypertensive crisis and leading to pulmonary edema or cerebral kravoizliv.Lechenie : alpha - and beta -blockers, alpha - blockers, peripheral control of the peripheral circulation , vasodilators - nitrate and sodium nitroprusside .
5 . STORAGE adrenaline
Store in original container , protected from light place , at temperatures below 25 ° C. Do not freeze !
It should not be used after the expiry date stated on the pack .
6 . ADDITIONAL INFORMATION
What does Adrenaline
The active substance is adrenaline (epinephrine) 1 mg in 1 ml of solution for injection . The other ingredients are tartaric acid , sodium chloride , sodium metabisulfite , disodium edetate , water for injections.
Looks like Adrenaline Sopharma and contents of the pack
Injection 1 mg / ml -1 ml, 10 ampoules in PVC foil , 1 or 10blistera in a cardboard box along with a leaflet with instructions for use.