Acyclovir table. 400 mg. 10 tablets

Acyclovir table. 400 mg. 10 tablets
€ 15.00
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Acyclovir is a synthetic antiviral Actavis product that acts on the human herpes viruses, varicella and ditomegalovirusa. After passing several transformations it inhibits viral DNA cell it so inhibits infection.



Acyclovir table. 400 mg. 10 tablets
 

ACTION:

Acyclovir is a synthetic antiviral Actavis product that acts on the human herpes viruses, varicella and ditomegalovirusa. After passing several transformations it inhibits viral DNA cell it so inhibits infection.
 

INDICATIONS:

 
 Treatment of infections of the skin and mucous membranes, including primary and recurrent genital herpes caused by Herpes simplex BHpyc (HSV-lHHSV-2);
 Suppression of recurrence in recurrent infections caused by Herpes simplex virus in patients with preserved immunity;
 Treatment of Varicella and Herpes zoster, caused by the Varicella zoster virus (VZV);
 Treatment of severe immune deficiency in patients with advanced HIV infection and those with end-stage disease or after bone marrow transplant ^;
 Prevention of herpes virus infections.
 
 

INFORMATION. REQUIRED BEFORE USE

 
 
CONTRAINDICATIONS:
 
 Hypersensitivity to the product;
 Pregnancy and lactation.
 
 

SPECIAL PRECAUTIONS FOR USE

 
In patients treated with high doses of Aciclovir Actavis is necessary to maintain adequate fluid intake.
 

 

DRUG INTERACTIONS AND OTHER
 
Concomitant administration of probenecid and cimetidine may reduce the renal clearance product.
 
 

SPECIAL WARNINGS FOR USE IN SPECIFIC PATIENT GROUPS

 
In elderly patients is necessary to maintain adequate water balance and dose reduction.
 
Pregnancy and lactation
 
The product is used during pregnancy only after a rigorous risk / benefit assessment. Established high concentration in milk products. For this reason, the product is used with caution in nursing mothers
 
 

EFFECTS ON ABILITY TO DRIVE AND USE MACHINES

 
Actavis acyclovir does not affect the ability to drive and use machines.
 

INFORMATION FOR PROPER USE DOSAGE

 
 In patients with infections caused by Herpes simplex virus - 200 mg 5 times daily for four hours for five days, but in severe infections, treatment may be continued;
 In patients with severe immune deficiency (after bone marrow transplantation or in patients with impaired absorption from the gut) - 400 mg five times daily for four hours;
 In patients at risk of infections caused by Herpes simplex, including genital herpes, the 200 mg two to four times daily for six months, ie while there is a risk of herpes infection. In infections caused by Herpes zoster apply 800mg every 5 hours for 7 days.
 
For prevention and treatment of herpes infection in children over 2. age using the same dose as adults. In children under age 2 product is applied to 200 mg or 20 mg / kg four times daily for 5 days;
 In patients with renal insufficiency, the dose should be reduced according to creatinine clearance. When renal function is the interval between doses is extended - with creatinine clearance below 50 ml / min interval was extended from 8 to 12 hours without a dose reduction, with creatinine clearance 10-0 ml / mm / l, 73 t 3 dose was halved and the interval between doses is extended to 24 hours;
 In elderly patients is necessary to maintain adequate water balance and dose reduction
Application of the product should be initiated as soon as possible before the start of infection. When recurrence is best to start during the prodromal period.
 
  OPERATION OF OVERDOSE
 
In case of accidental overdose repeated for several days, symptoms such as nausea, vomiting and headache. Risk of crystallisation of the product in the renal tubules. It is necessary to maintain a constant and adequate diuresis while taking the product. Chronic poisoning must be considered for dialysis to remove the product.
 

SIDE EFFECTS

 
During treatment with this product may experience the following side effects:
 On behalf of the gastrointestinal tract - nausea, vomiting, diarrhea, stomach pain;
 On behalf of blood - low red and white blood cells and platelets;
 Allergic reactions - skin rashes, photosensitivity, rarely anaphylaxis;
 On behalf of the urinary system - elevated creatinine and urea
 From the liver - reversible increases in liver enzymes;
 Neurological - headaches, dizziness, hallucinations, drowsiness;
 General - fatigue and muscle weakness.
 

STORAGE

 
At temperatures below 25 ° C. Keep out of reach of children!
 

SHELF LIFE

 
2 (two) years.
 
Do not use after the expiry date stated on the package.
INGREDIENTS:

Active substance in one tablet: Aciclovir 400 mg

Excipients: microcrystalline cellulose, sodium starch glycolate, povidone, magnesium stearate
€ 15.00
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