Acyclovir AL. 800 mg. 35 tablets
Herpes zoster the prevention of severe cases of herpes simplex virus infections in patients with a depressed immune defense at increased risk for infections, e. after organ transplants.
Acyclovir AL. 800 mg. 35 tablets
What is Acyclovir AL and what it is used
Acyclovir AL is a medicinal product for the treatment of viral infections .
Acyclovir is used in the AL :
Herpes zoster the prevention of severe cases of herpes simplex virus infections in patients with a depressed immune defense at increased risk for infections , e. after organ transplants.
Before taking Aciclovir AL
Do not take Aciclovir AL if you are:
With known hypersensitivity to aciclovir or any of the other ingredients of the medicinal product;
If you have an abnormal renal function or decreased urine production (less than 100 ml of urine per day ), you should not use Acyclovir AL prevention , as there are no data on the use of aciclovir tablets under these conditions.
Take special care with Aciclovir AL :
What you should consider when deciding to use this drug in the elderly :
Elderly patients often suffer from kidney failure. It is therefore recommended in this age group to monitor renal function and to increase the amount of fluid in the pill Aciclovir AL . Your doctor will determine the appropriate dosage (see " How to take Acyclovir AL " ) .
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
For other drugs which are known to interfere with the effect of AL Acyclovir
Probenecid ( uricosuric drug for lowering the level of uric acid in the blood) reduces secretion of Acyclovir AL by the kidney , which can lead to a prolongation of the residence time in the body of acyclovir .
Probenecid and cimetidine increase the plasma concentration of acyclovir and decreased excretion by the kidneys. Reported higher levels of plasma concentrations of acyclovir when mycophenolate mofetil ( medicine depressingly normal immune functions of the body ) was administered with aciclovir in comparison to administration of aciclovir alone . It is not necessary , however, dosage adjustment because of the wide therapeutic index of aciclovir . No significant increase in toxicity in patients receiving antiretroviral oral therapy ( Zidovudine ) for coadministration of acyclovir .
Pregnancy and lactation
The physician should carefully consider the ratio between the expected benefits and potential risks to pregnant women in whom treatment with aciclovir AL necessary. Acyclovir is found in breast milk after taking acyclovir tablets . For this reason, while acyclovir tablet- feeding should be discontinued.
Driving and using machines
There is no known direct effect on the ability of acyclovir and a reaction drive . It should be borne in mind, however , that in rare cases may occur side effects such as drowsiness , dizziness and hallucinations, particularly in patients with impaired renal function.
3 . How to take Acyclovir AL
Always take AL Acyclovir exactly as prescribed by your doctor . If you have doubts and questions, ask your doctor or pharmacist.
Dosing and administration , duration of therapy:
These instructions apply only if your doctor has prescribed otherwise in respect of the drug Aciclovir AL. Please follow the instructions for use, or those given by your doctor as otherwise Aciclovir AL will have the necessary effect and safety.
In what quantities and how often you should take Aciclovir tablets AL ?
Dosing schedule :
Herpes zoster :
Aciclovir AL 1 tablet (800 mg acyclovir ) 5 times a day every 4 hours during the day .
Patients with renal insufficiency :
Patients with abnormal renal function , occurring especially in the elderly may need a reduced dose acyclovir compared shown above . In abnormal kidney function , your doctor will determine the appropriate dosage according to renal function ( see below ) : Indication Creatinine clearance (ml/min/1.73 m2) Serum creatinine (?mol / l or mg / dl) doses ( single dose )
Shingles 25-10 280-550
3:17 to 6:22 370-750
4:18 to 8:45 1 tablet Aciclovir AL (800 mg acyclovir ) 3 times a day ( every 8 hours )
<10 > 550
> 6.22 > 750
> 8.48 1 Tablets Aciclovir AL (800 mg acyclovir ) 2 times daily ( every 12 hours)
How and when should I take Acyclovir AL
The tablets should be swallowed unchewed , after eating a sufficient quantity of fluid (e.g. a glass of water ) .
Increased amount of fluid should be taken when using acyclovir tablet AL , especially in patients with impaired renal function.
To achieve good results , treatment with Aciclovir AL should begin immediately with the onset of the first symptoms of infection.
Especially in recurrent infection with herpes simplex virus , acyclovir AL intake should begin at the first signs of a new infection (itching , discomfort , the first bubbles ) .
How long can you take Acyclovir AL
The duration of treatment will solve your doctor .
Infections caused by the herpes zoster virus, the duration of treatment with aciclovir AL is usually 5-7 days, but the clinical condition in some patients may require longer treatment.
If you have flowed more than the required dose Aciclovir AL ( intentional or accidental overdose of this medicine )
Overdose of Acyclovir AL should not expect poisoning. A single dose of 5 g acyclovir no symptoms of poisoning occur . Missing data on one administration of higher doses . In case of overdose and worsening of adverse reactions or any doubt , contact your doctor .
If you forget to take or you take less than the prescribed amount Aciclovir AL
Do not take a double dose acyclovir tablet AL when it is next and continue treatment as prescribed by your doctor .
If you miss more than one station or you take less than the prescribed amount , consult your doctor .
If you stop taking acyclovir AL
Even if the condition improves , the intake of AL Acyclovir should continue as prescribed by your doctor to ensure the success of treatment. If in doubt about side effects , please consult with your doctor before you interrupt or stop treatment prematurely.
4 . Possible side effects
What side effects may occur in the administration of aciclovir AL
Like other drugs Acyclovir AL can cause side effects , even though they do not occur in any treated patient with this drug .
For the evaluation of the side effects has been used , the following classification based on their occurrence frequency :
Very common: More than 1 in 10 patients treated ;
Common: When less than 1 in 10 , but more than 1 in 100 patients treated ;
Uncommon: Less than 1 in 100 but more than 1 in 1000 patients treated ;
Rare : If less than 1 in 1,000 , but more than 1 in 10 000 patients treated ;
Very rare in less than 1 in 10 000 patients treated, including isolated instances ;
Not known from the available data can not be estimated .
Blood and lymphatic system disorders:
Very rare : anemia , leukopenia, thrombocytopenia.
Immune system disorders :
Rare: Anaphylaxis ( allergic immediate reactions manifested by redness , itching, swelling , shock ) .
Psychiatric and nervous system disorders :
Common: Headache, dizziness ;
Very rare : agitation , confusion, tremor ( involuntary , rapid alternating contraction and relaxation of muscle groups . ) , Ataxia (inability to coordinate muscle activity in performing voluntary movements) , dysarthria ( difficulty speaking - to distort the pronunciation of sounds ) , hallucinations, psychotic symptoms, convulsions, somnolence , encephalopathy ( disorders of the brain - metabolic, degenerative ) , coma .
The above side effects are usually reversible, reported primarily in patients with renal impairment or where there are other predisposing factors.
Respiratory, thoracic and mediastinal disorders:
Rare: dyspnoea ( difficulty breathing) .
Common: Nausea , vomiting , diarrhea, abdominal pain.
Hepatobiliary (liver and gallbladder ) disorders
Rare: Reversible elevations in bilirubin and liver enzymes;
Very rare: Hepatitis ( jaundice) .
Skin and subcutaneous tissue disorders:
Common: pruritus, rash (including photosensitivity ) ;
Uncommon: Urticaria (hives ) . Enhanced diffuse hair loss. This process is associated with many diseases and drugs , such as the relationship with the use of acyclovir is not securely set ;
Rare: Angioedema (specific allergic reaction characterized by swelling of the face , lips, eyelids ) .
Renal and urinary disorders:
Rare: Increased blood urea and creatinine ;
Very rare : Acute renal failure.
General disorders and administration site conditions:
Common: fatigue, fever.
What measures should be taken in case of adverse reactions
If any of those listed in this leaflet gets serious or if you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
Shelf life :
The expiry date is printed on the carton and blister. Do not use after the expiry date. Date of expiry date refers to the last day of the indicated month.
5 . How to store Aciclovir AL
Keep out of reach of children!
6 . Additional Information
Contents of the pack of Acyclovir AL
1 tablet contains :
Active substance: Acyclovir 800 mg.
Excipients: Microcrystalline cellulose , copovidone , magnesium stearate , sodium starch glycolate, silicon dioxide.