AZIMED avium. 600 mg. 8 tablets
AZIMED avium. 600 mg. 8 tablets
WHAT AZIMED avium 600 mg film-coated tablet is and what are they used?
Azimed avium is a macrolide antibiotic from the group of azalides, a new generation macrolides. It inhibits protein synthesis in the bacterial cell and results in the treatment of certain infections.
Azimed avium 600 mg tablets are administered alone or in combination with rifabutin prophylaxis of infections caused by the group of Mycobacterium avium mtracellulare complex. These infections generally occur in patients with acquired immunodeficiency syndrome disease (AIDS) (caused by a virus of acquired immunodeficiency, HIV), which in the final stages of the disease.
DO NOT TAKE AZIMED avium:
- If you are allergic (hypersensitive) to the active substance, to other macrolide antibiotics or any of the other ingredients of Azimed avium;
In rare cases, serious allergic reactions (rarely fatal) as swelling of the face and pharynx, difficulty breathing and more. Tell your doctor if you are allergic to antibiotics or other drugs, or have any allergic disease.
As with other antibacterial drugs, there is the possibility of superinfection (additional superimposed infections associated with ongoing antibiotic treatment), eg. fungal.
It is possible that the development of pseudomembranous colitis (inflammation of the colon, occurring with severe and persistent diarrhea), which may be of varying severity. Let your doctor know if you develop diarrhea.
Tell your doctor if you have liver, kidney or heart disease.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Antacids (medicines to relieve heartburn)
Simultaneous ingestion of antacids that contain aluminum or magnesium, reduces the absorption of Azimed avium. It is recommended to apply at least 1 hour before or 2 hours after taking an antacid product.
Co-administration of Azimed avium and oral anticoagulants (drugs that prevent blood clots) can be observed an increased tendency to bleed.
Ergot alkaloids (medicines for the treatment of migraine)
Adoption of Azimed avium simultaneously with medicines of the ergot may lead to ergotism (ergot alkaloids poisoning, manifested by bruising limb claudication). Therefore, Azimed avium should not be taken with medicines of the ergot.
Terfenadine / Cisapride
Co-administration of Azimed avium with terfenadine or cisapride should be done with caution as it can lead to heart rhythm disturbances.
It has been found that macrolides (antibiotics group to which it belongs and Azimed avium) reacted with theophylline, digoxin, cyclosporin, astemizole, triazolam, midazolam. Although there are no data on the interaction of Azimed avium with these drugs, it is recommended concomitant use be carefully monitored. Your doctor may adjust the dosage of medication, if it considers it necessary.
ADMISSION OF AZIMED avium with food and drink
Azimed avium 600 mg tablets should be taken at least 1 hour before or 2 hours after meals.
Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine.
Azimed avium should not be used during pregnancy unless clearly necessary.
Azimed avium is excreted in breast milk. If you are breastfeeding, you should not take medicines containing azithromycin.
DRIVE AND USE MACHINES
Application of Azimed avium did not affect the ability to drive or operate machinery.
HOW TO TAKE AZIMED avium 600 mg film-coated tablets
Always take Azimed avium exactly as your doctor tells you. If you are not sure, ask your doctor or pharmacist
Azimed avium 600 mg film-coated tablets are taken once a week and the recommended dose is 1200 mg.
Azimed avium 600 mg tablets should be taken 1 hour before or 2 hours after meals.
Not been established efficacy and safety of Azimed avium prophylaxis MAC infection in children.
Patients with renal insufficiency
In patients with mild renal impairment is not necessary to adjust the dosage. There are no data on use in patients with moderate and severe renal impairment, and therefore in such cases should be approached with caution.
Patients with hepatic impairment
Azithromycin is processed by the liver and excreted in the bile and not be used in patients with severe liver failure.
If you take more dose Azimed avium
When taking a higher dose of that ask for advice from a doctor!
No evidence of an overdose of azithromycin. Overdose with other drugs in the same group occurs with transient hearing loss, severe nausea, vomiting and diarrhea. In this case it is necessary to induce vomiting and seek immediate medical attention.
If you forget to take Azimed avium
If you forget to take the next dose then take the missed as soon as possible, but do not take the same time to the next. Do not take a double dose to make up for a missed dose.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
POSSIBLE SIDE EFFECTS
Like all medicines, Azimed avium can cause side effects, although not everybody gets them.
Common side effects (seen in more than 1 in 100 people taking Azimed avium)
- Nausea, vomiting, diarrhea, stomach discomfort.
Uncommon side effects (seen in more than 1 in 1000 people who have taken Azimed avium)
- Dizziness, drowsiness, headache, seizures, change in taste;
- Flatulence, indigestion, loss of appetite, loose stools;
- Allergic reactions including rash and persistent itching;
- Joint pain
- Burning or itching in the vagina (vaginitis).
Rare side effects (seen in more than 1 in 10,000 people who have taken Azimed avium)
- Reducing the number of blood platelets, which increases risk of bleeding or bruising (thrombocytopenia); mild and transient decrease in the number of white blood cells (neutropenia) without a confirmed causal relationship;
- Aggression, anxiety, nervousness;
- Tingling, general weakness (asthenia), insomnia, hyperactivity;
- Hearing disorders, deafness, tinnitus, usually at high doses and prolonged administration, in most cases, these disturbances were transient;
- Palpitations, irregular heartbeat, rapid heartbeat; abnormal lowering of the blood pressure (hypotension);
- Constipation, discoloration of the tongue, irritation of the colon, occurring with severe and persistent diarrhea (pseudomembranous colitis), inflammation of the pancreas;
- Hepatitis, yellowing of skin and whites of the eyes (jaundice), elevated liver enzymes, liver necrosis; liver failure;
- Allergic reactions including swelling of the face and pharynx, itchy, red skin (hives), photosensitivity; severe skin diseases accompanied by blistering of the skin, mouth, eyes and genitals;
- Nephritis, acute renal failure /
- Fungal infections of the vagina.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
HOW TO STORE AZIMED avium
Do not store above 25 ° C. Keep out of reach of children!
Do not use Azimed avium after the expiry date stated on the carton. The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
What does Azimed avium 600 mg film-coated tablets
The active substance is azithromycin. Each tablet contains azithromycin dihydrate equivalent to 600 mg azithromycin.
Other ingredients are: corn starch, pregelatinized, calcium hydrogen phosphate anhydrous, croscarmellose sodium, magnesium stearate, sodium lauryl sulfate, Opadry II White Y-30-18037.