AXETINE 1.5 g. 10 vials

MEDOCHEMIE
AXETINE 1.5 g. 10 vials
€ 39.00
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WHAT AXETINE AND WHAT IT IS USED
The name of your medicine is AXETINE and contains cefuroxime as cefuroxime sodium. Cefuroxime is one of the group of drugs known as antibiotics. They help your body fight infections. Cefuroxime works by killing the micro-organisms (bacteria) that cause infection.
AXETINE used to treat many different types of infections caused by susceptible antibiotic microorganisms, including respiratory tract infections (such as infected bronchiectasis, acute and chronic bronchitis, pneumonia and lung abscess), ear infections (otitis media), the nose (sinusitis ) and throat infections (pharyngitis, tonsillitis), infections of the skin, soft tissues (cellulitis, erysipelas and wound infections), infections of bones and joints (septic arthritis and osteomyelitis), and urinary tract infections (asymptomatic bacteriuria, cystitis and acute, or chronic pyelonephritis). It is also used to treat diseases, sexually transmitted (gonorrhea / "gonorrhea"), gynecological infections (pelvic inflammatory disease), meningitis (inflammation of the lining of the brain) and septicemia (bacterial infection of the blood). It is also used before some operations to protect you from getting an infection after surgery.
In combination with other antibiotics (e.g. metronidazole or aminoglycosides), cefuroxime is indicated for the prevention of colorectal (colon and rectum) and gynecological infections.
Your doctor will tell you what kind of infection being treated or what was appointed cefuroxime.

2. BEFORE YOU TAKE AXETINE
Do not take AXETINE
if you are allergic (hypersensitive) to cefuroxime or to other cephalosporin antibiotics.
Take special care with AXETINE
If you have ever had a rash, itching, swelling of the face or wheezing while breathing, difficulty breathing (allergic) reaction to antibiotics such as penicillin or cephalosporin;
You suffer from any kidney problems or are on dialysis;
Suffer from gastrointestinal disease called colitis.
In patients with a limited intake of sodium, it should be noted that the equivalent of 1 g cefuroxime contains approximately 2.2 mmol of sodium.
Cephalosporins group which is cefuroxime may be associated with decreased prothrombin activity (a disorder of blood clotting). Risk are patients with kidney or liver failure, malnutrition, and patients on prolonged antibiotic treatment and those who have previously stabilized on anticoagulant (anti-clotting) therapy. At-risk patients should be monitored indicator of blood clotting, known as prothrombin time and if it is shown to apply their vitamin K.

Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription:
Water tablets (diuretics)
Antibiotics like aminoglycosides;
Probenecid, a drug used to treat gout.
Pregnancy and lactation
If you are pregnant or trying to get pregnant, ask your doctor or pharmacist before taking any medicine, including AXETINE.
There are no adequate data from the use of AXETINE during pregnancy. The application should be made after a rigorous assessment by the physician of the benefits of treatment and the potential risk to the fetus.
If you are having this medicine and breast-feed should discuss this with your doctor as cefuroxime is excreted in milk in small quantities. It is recommended that nursing be discontinued.

Driving and using machines
No effects of AKSETIN on ability to drive and use machines.

3. HOW TO APPLY AKSETIN
Always use AKSETIN exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist. If possible, before starting treatment, always read the printed leaflet.
This medicine will be placed by a doctor or nurse, as it applies or as an injection into the muscle (intramuscular injection) or as an infusion. If you receive a high dose can be administered in two divided muscle. It can be injected directly for about two or three minutes, into a vein (intravenous injection). If you receive a large volume of fluid into a vein, AXETINE can be added to the liquid (intravenous infusion). Your doctor will prescribe the dose drug that is suitable for you, depending on the type of infection and other diseases that you may have. If you ask the person who puts your medication, he / she will tell your doctor what dose you are prescribed a medicine, how often you are prescribed to do and for how long.

General dosage recommendations:
Adults: For most adults, the usual dose is 750 mg every six or eight hours. In very severe infections, you may make a 1.5 g every six or eight hours. If you have kidney disease, you may be placed 750 mg every twelve or twenty-four hours.

Neonates, infants and children (28 days to 11 years): The usual dose is 60 mg / kg body weight every day. They will be separated and will be made every eight or six hours.

Newborn babies, including premature: usually need 30 to 100 mg / kg body weight daily. They will be divided equally be applied every eight to twelve hours.

Meningitis:
Adults and children treated for meningitis may need a larger dose cefuroxime.
Adults: 3 g intravenously every 8 hours.
Infants and children: 150 to 250 mg / kg / 24 hours intravenously administered in three or four divided doses.
Infants: 100 mg / kg / 24 hours intravenously. After three days, or after the onset of clinical improvement, the dose may be reduced to 50mg / kg / day.

Gonorrhea: If you treat gonorrhea, "gonorrhea", will be made a single dose of 1.5 g, usually as two intramuscular injections of 750 mg, one in each side of the seat.

Prevention: normally 1.5 g intravenously with induction of anesthesia for abdominal, pelvic and orthopedic operations, as may be supplemented by two injections of 750 mg intramuscularly 8 and 16 hours later. At heart, lung operations, surgery of the esophagus and vascular operations, the usual dose is 1.5 g intravenously at induction of anesthesia, extended 750 mg intramuscularly three times a day for another 24-48 hours.
Upon complete joint prosthesis, 1.5 g cefuroxime powder for injection, may also be mixed as dry with each package of methyl methacrylate cement polymer before adding the liquid monomer.

Pneumonia: 1.5 g three times daily (iv), for 48 to 72 hours, followed by oral administration of 500 mg of cefuroxime axetil in the form of an ester for oral administration twice daily for 7-10 days.

Severe exacerbations of chronic bronchitis 750 mg cefuroxime sodium, TID (iv or im) for 48 to 72 hours, followed by oral administration of 500 g of cefuroxime axetil in the form of an ester, twice daily for 5-10 days.

In patients with kidney problems AXETINE dose will be reduced.

Elderly: dosage as in adults.

If you take more dose AXETINE
It is unlikely that you do more of this medicine by your nurse or your doctor. Your doctor and nurse will monitor disease progression and drug verify that you are doing. Always ask if you are not sure why you are doing this dose of medicine.

If you forget to take AXETINE
Your doctor or nurse will have instructions on when you are doing this medicine. It is unlikely that you will not make the drug in the way your appointed. If you think you might miss a dose, then talk to your nurse or doctor.
Do not take two doses to make up for missed.

If you stop taking AXETINE
It is important to make the course of treatment prescribed by your doctor. You may begin to feel better, but it is important not to stop use of this medicine unless your doctor advises otherwise your condition may get worse again.

4. POSSIBLE SIDE EFFECTS
Like all medicines, AXETINE can sometimes cause side effects, although not everybody gets them.
Tell your doctor immediately if you experience any of these side effects:
Sudden wheezing and chest pain or tightness in the chest;
Swelling of eyelids, face and lips.
Common side effects:
These may affect up to 1 in 10 patients:
Changes in blood counts or liver test results;
Pain or inflammation at the injection site (thrombophlebitis).
Uncommon side effects:
These may affect up to 1 in 100 patients:
skin rash, urticaria and pruritus.

5. HOW TO STORE AXETINE
Keep at temperatures below 25 ° C Store in the original container. Store in a dry place, protected from light.
After dissolution, the solution / suspension was stored in a refrigerator (2-8 ° C) to a maximum of 24 hours.
Do not use the medicinal product after the expiry date stated on the carton and label.
Medicines should not be disposed of in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. ADDITIONAL INFORMATION
What AXETINE
The active substance is cefuroxime (cefuroxime) as cefuroxime sodium;
Does not contain other ingredients.
AXETINE looks like and contents of the pack
Supplied in clear glass vials containing sterile powder, white to pale yellow. The vials contain 1500 mg cefuroxime. Supplied in packs of 10 and 100 vials.
Not all pack sizes may be marketed.
€ 39.00
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