AVERNOL. 25 mg. 30 tablets
AVERNOL. 25 mg. 30 tablets
Carvedilol is a nonselective beta-adrenergic blocker / cardiovascular agent /. It has an antihypertensive effect and helps to reduce blood pressure.
Avernol be used:
- For the treatment of hypertension
- In addition to the standard therapy of stable chronic heart failure in patients with euvolemiya.
- As a prophylactic treatment of stable angina pectoris.
BEFORE YOU TAKE Avernol
Do not take Avernol, if you have:
- Hypersensitivity to the Carvedilol or to any of the excipients of the tablets
- History of asthma or other pneumopathies
- Deteriorating heart failure or fluid treatment that needs medical treatment
Heart block second or third degree and no pacemaker
- Severe bradycardia
- Cardiogenic shock
- Syndrome sick sinus
- Severe hypotension
- Pheochromocytoma or metabolic acidosis
- Liver failure
Avernol is contraindicated in patients under 18 years of age
Before taking Avernol tell your doctor if you have:
- Bradycardia, variant angina Prinmetel, or other heart problems
- Chronic heart failure, hypertensive heart disease and other
- Kidney problems
- Thyroid problems
- Psoriasis or a history of psoriasis
- Syndrome Raynaud / circulatory disorder /
- Asthma or a tendency to bronchospasm or other pulmonary diseases. Avernol should not be used in patients with a history of wheezing due to asthma or other lung diseases.
- A history of severe hypersensitivity reactions
Women who become pregnant during treatment with Avernol should immediately contact their physician.
In case of surgery, tell the doctor that you are taking Avernol.
Patients with diabetes should monitor their blood sugar regularly as carvedilol may mask early signs of acute hypoglycemia. Regular monitoring is also shown when starting or increased dosage of Avernol. Hypoglycaemic therapy should be adjusted accordingly.
If you wear contact lenses you should consider that during treatment may manifest decreased production of tears.
Avernol may mask the symptoms of thyrotoxicosis.
HOW TO TAKE AVERNOL
The precise dosage and duration of treatment is determined by the doctor. Dosing regimens as mentioned below are merely indicative. If you have any questions, ask your doctor or pharmacist.
Do not chew the tablets. Swallow it with a little water.
Take them with a meal if you have chronic heart failure.
A / symptomatic chronic heart failure:
Treatment should be initiated under the supervision of a physician after careful consideration of the patient's status. Before any change in dosage is also required clinical judgment.
If you are taking diuretics and / or digoxin and / or ACE inhibitors, their dose should be stabilized before starting treatment with Avernol.
Changing the dose should be individualized.
In patients with worsening heart failure or decompensation or unstable heart failure, the dose should not be increased.
Adults and the elderly:
Treatment was initiated with 3,125 mg twice daily for the first two weeks. If tolerated Avernol dose was increased to 6.25 mg twice a day to 12.5 mg twice a day, and then to 25 mg twice a day, at intervals of at least two weeks. The dose may be increased to the highest level of tolerance. The recommended maximum daily dose for patients with mild to moderate chronic heart failure, weighing less than 85 mg for all patients with severe chronic heart failure is 25 mg given twice daily. for patients with mild to moderate chronic heart failure weighing over 85 kg the recommended maximum daily dose is 50 mg twice daily.
Patients with systolic blood pressure <100 mm Hg can reach deterioration of renal and / or cardiac function during the escalation, so before any increase in dose should be done careful assessment of renal and cardiac status of the patient.
Transient worsening of heart failure, vasodilation or fluid can be treated with a change or discontinuation of treatment with Avernol or by adjusting the dose of diuretics or ACE inhibitors. Avernol dose should not be increased until symptoms of worsening heart failure or vasodilation not stabilize.
If the treatment is interrupted Avernol for more than two weeks, the treatment can be started again with 3,125 mg twice a day, and to make the above-described increase of the dose.
In / Hypertension
It is recommended once daily dosing.
Adults and the elderly:
The starting dose for the treatment of hypertension is 12.5 mg once daily for two days. The dose may be increased to 25 mg once a day, which is considered sufficient for the control of hypertension in most patients. If necessary, the dose may be increased to 50 mg once daily or 25 mg twice daily. Increases should be made at intervals of at least two weeks.
C / Angina
The starting dose for the treatment of angina was 12.5 mg carvedilol twice daily for two days. Then you have to give 25 mg twice daily.
Do not use in children under 18 years of age
Avernol is contraindicated in patients with hepatic impairment or any other liver disease.
It is not necessary to change the dose if systolic pressure is over 100 mm Hg.
Avernol should not be used in pregnancy unless the expected benefits do not outweigh the potential risks.
Avernol should not be used during lactation.
Discontinuation of the treatment should be done gradually and under drug monitoring, especially in patients with ischemic heart disease. If Avernol treatment is stopped suddenly, you may experience side effects. If you are taking clonidine concomitantly with Avernol not stop until your doctor tells you.
During treatment with Avernol, patients should be advised not to drive or operate machinery if you have fatigue, dizziness, or similar symptoms. These effects are enhanced in conjunction with alcohol. Do not drink alcohol while you are taking Avernol.
POSSIBLE SIDE EFFECTS
If you exanthema, pruritus, or if you have difficulty breathing, contact your doctor. Do not stop taking Avernol, but follow the doctor's instructions.
At the beginning of treatment with carvedilol some patients may have dizziness, especially when standing, fatigue, headache, nausea and abdominal pain. They may also vomit or have diarrhea. These symptoms were mild and transient with continued therapy without the need for additional measures to control them.
Other adverse reactions are: sleep disturbances, depression, paresthesia, asthenia, bradycardia, cold hands or feet, swollen legs, tingling or pain in the extremities, decreased tear production, visual disturbances, weight gain and hypercholesterolemia, asthma and wheezing in patients with predisposition.
Also, skin reactions such as allergic exanthema, dermatitis, urticaria, pruritus, skin lesions.
Patients with preexisting diabetes may experience hyperglycemia, hypoglycemia and worsening blood sugar.
Less frequent side effects such as chest pain, hypotension, other heart problems, wheezing and flu-like symptoms, dry mouth or dry eyes, blurred vision, increased sweating, constipation and vomiting. Rarely in men can manifest impotence. Rarely can occur transient renal failure, leading to swelling of the limbs or face. Also, other disorders of renal function in patients with diffuse vascular disease and / or impaired renal function.