AVERNOL table. 6.25 mg
Avernol use: For the treatment of hypertension
In addition to the standard therapy of stable chronic heart failure in patients with euvolemiya. as a prophylactic treatment of stable angina.
AVERNOL table. 6.25 mg
Carvedilol is a nonselective beta-adrenergic blocker / cardiovascular / agent. It has antihypertensive effect and helps to reduce blood pressure.
For the treatment of hypertension
In addition to the standard therapy of stable chronic heart failure in patients with euvolemiya.
As a prophylactic treatment of stable angina.
BEFORE YOU TAKE Avernol
Do not take Avernol, if you have:
Hypersensitivity to the Carvedilol or any of the excipients of the tablet
History of asthma or other pneumopathies
Deteriorating heart failure or fluid retention treatment that needs medical treatment
Heart block second or third degree and no pacemaker
Syndrome sick sinus
Pheochromocytoma and metabolic acidosis
Avernol is contraindicated in patients under 18 years of age
Before taking Avernol tell your doctor if you have:
Bradycardia variant angina Prinmetel, or other heart problems
Chronic heart failure, high blood pressure and other heart problems
Psoriasis or a history of psoriasis
Syndrome Raynaud / circulatory disorder /
Tendency to asthma or bronchospasm or other pulmonary diseases. Avernol should not be used in patients with a history of wheezing due to asthma or other lung diseases.
A history of severe hypersensitivity reactions
Women who become pregnant during treatment Avernol should immediately contact their physician.
If you have surgery, tell the doctor that you are treated with Avernol.
Patients with diabetes should monitor their blood sugar regularly as carvedilol may mask early signs of acute hypoglycemia. Regular monitoring is also shown when starting or increased dosage of Avernol. Hypoglycaemic therapy should be adjusted accordingly.
If you wear contact lenses you should consider that during the treatment may occur reduced production of tears.
Avernol may mask the symptoms of thyrotoxicosis.
HOW TO TAKE AVERNOL
The exact dose and duration of treatment is prescribed by a doctor. Dosing schedule mentioned below are indicative only. If you have any questions, ask your doctor or pharmacist.
Do not chew the tablets. Swallow them with a little water.
Take it with food if you have chronic heart failure.
A / symptomatic chronic heart failure:
Treatment should be initiated under the supervision of a physician after careful evaluation of the patient status. Before any change in dose is also necessary clinical judgment.
If you are taking diuretics and / or digoxin and / or ACE inhibitors, their dose should be stabilized before initiating therapy with Avernol.
Changing the dosage should be individualized.
In patients with worsening heart failure or decompensation or unstable heart failure, the dose should not be increased.
Adults and the elderly:
Treatment begins with 3.125 mg twice daily for the first two weeks. If Avernol tolerated dose was increased to 6.25 mg twice daily to 12.5 mg twice daily and then to 25 mg twice daily at intervals of at least two weeks. The dose may be increased to the highest level of tolerance. The recommended maximum daily dose for patients with mild to moderate chronic heart failure of less than 85 mg for all patients with severe chronic heart failure is 25 mg given twice daily. for patients with mild to moderate chronic heart failure weighing over 85 kg the recommended maximum daily dose is 50 mg twice daily.
Patients with systolic blood pressure <100 mm Hg can reach deterioration of renal and / or cardiac function during the escalation, so before any increase in dose should be done careful assessment of renal and cardiac status of the patient.
Transient worsening of heart failure or vasodilation fluid can be treated with a change or discontinuation of treatment Avernol either by adapting the dose of diuretics or ACE inhibitors. Avernol dose should not be increased until symptoms of worsening heart failure or vasodilation is not stabilized.
If Avernol treatment is interrupted for more than two weeks, treatment can be restarted at 3.125 mg twice daily and make the above-described increase in dose.
I / Hypertension
It is recommended once daily dosing.
Adults and the elderly:
The starting dose for the treatment of hypertension is 12.5 mg once daily for two days. The dose may be increased to 25 mg once daily, which is considered sufficient to control hypertension in most patients. If necessary, the dose may be increased to 50 mg once daily or 25 mg twice daily. Increases should be made at intervals of at least two weeks.
C / Angina
The starting dose for the treatment of angina was 12.5 mg carvedilol twice daily for two days. Then you have to give 25 mg twice daily.
Do not use in children under age 18
Avernol is contraindicated in patients with hepatic impairment or any other liver disease.
It is not necessary to change the dose if systolic pressure is over 100 mm Hg.
Avernol should not be used during pregnancy unless the expected benefits do not outweigh the potential risks.
Avernol should not be used during breastfeeding.
Discontinuation of therapy should be done gradually and under medication monitoring, particularly in patients with ischemic heart disease. If Avernol treatment is stopped suddenly, you may experience side effects. If you are taking clonidine while Avernol not stop until your doctor tells you to.
During treatment Avernol, patients should be advised not to drive or operate machinery if you have fatigue, dizziness or related symptoms. These effects are enhanced with alcohol. Do not drink alcohol while you are being treated with Avernol.
POSSIBLE SIDE EFFECTS
If you exanthema, pruritus, or if you have difficulty breathing, contact your doctor. Do not stop taking Avernol, but follow your doctor's instructions.
Early treatment with carvedilol some patients may have dizziness, especially when standing, fatigue, headache, nausea and abdominal pain. They may also vomit or have diarrhea. These symptoms are mild and transient with continued therapy without the need for additional measures to control them.
Other side effects include: sleep disturbances, depression, paresthesia, asthenia, bradycardia, cold hands and feet, swollen feet, tingling or pain in the extremities, decreased tear production, visual disturbances, weight gain and hypercholesterolemia, asthma and wheezing in patients predisposed.
Also, skin reactions such as allergic exanthema, dermatitis, urticaria, pruritus, skin lesions.
In patients with pre-existing diabetes may experience hyperglycemia, hypoglycemia and worsening blood sugar.
Less side effects such as chest pain, hypotension, other heart problems, wheezing and flu-like symptoms, dry mouth or dry eyes, blurred vision, increased sweating, constipation, and vomiting. Rarely, males may manifest impotence. Rarely can occur transient renal failure, leading to swelling of the limbs or face. Also, some impairment of renal function in patients with diffuse vascular disease and / or impaired renal function.