APIRI. 100 mg. 30 tablets

APIRI. 100 mg. 30 tablets
€ 9.00
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unstable angina pectoris - as part of standard therapy;
acute myocardial infarction - as part of standard therapy;
prevention of recurrent myocardial infarction;
after surgery or other interventions of arteries (eg ACVB, PTCA); 

APIRI. 100 mg. 30 tablets

 
 
APIRI WHAT IS AND WHAT IT IS USED
Apiri is indicated for:
unstable angina pectoris - as part of standard therapy;
acute myocardial infarction - as part of standard therapy;
prevention of recurrent myocardial infarction;
after surgery or other interventions of arteries (eg ACVB, PTCA);
prevention of transient ischemic attacks and cerebral infarction after onset of symptoms;
reduce the risk of primary myocardial infarction in people with cardiovascular risk factors such as diabetes mellitus, hyperlipidemia, hypertension, smoking, old age.

2. BEFORE YOU TAKE APIRI
Do not use Apiri:
if you are allergic (hypersensitive) to acetylsalicylic acid, to salicylates or any other ingredients of Apiri;
If you have active ingredients Apiri;
If you have active ulcers of the stomach or duodenum;
if you have abnormal bleeding disorder.
Take special care with Apiri:
if you are hypersensitive to other anti-inflammatory / anti-rheumatic drugs and other allergenic substances;
if you take both anticoagulants (eg coumarin derivatives, heparin except low-dose heparin);
if you suffer from asthma;
if you have a chronic or current gastric or duodenal complaints;
if you have a pre-existing renal impairment;
if you have severe hepatic impairment;
if you have asthma, hay fever, nasal polyps, chronic respiratory infections (especially if accompanied by fever) or allergic (eg skin reactions, pruritus, rash);
if you are hypersensitive to analgesics, anti-inflammatory and antirheumatic drugs with risk of asthma attacks (analgesic intolerance / analgesic-induced asthma). It is necessary to consult a doctor before using the product. The same applies to patients who are allergic to other substances in the form of skin reactions, pruritus, rash;
before surgery is necessary to consult or inform the doctor or dentist that you are taking Apiri.
children:
Apiri should not be taken by children or adolescents under conditions of high temperature, unless recommended by a doctor or other therapeutic measures have failed. Prolonged vomiting in connection with these diseases may be a sign of the syndrome Rey - very rare but life-threatening disease that requires immediate medical treatment.
Medicinal products containing aspirin should not be taken continuously without consulting a doctor or dentist.

Using other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained on prescription.

Apiri enhances the effect of:
effect of anticoagulants (eg coumarin, heparin);
risk of gastrointestinal bleeding when taken simultaneously with corticosteroids or alcohol;
effects of oral antidiabetic agents (sulphonylureas);
Effects and side effects of methotrexate;
plasma concentrations of digoxin, barbiturates and lithium;
effects and side effects of nonsteroidal analgesic / anti-inflammatory /;
antirheumatic drugs;
The effects of sulfonamides and sulfonamide combinations, e. sulfamethoxazole / trimethoprim;
effect of triiodothyronine;
the effect of valproic acid.
Apiri weakens the effects of:
aldosterone antagonists (spironolactone and canrenoate);
loop diuretics (eg furosemide);
antihypertensives;
urikozurnichni agents (eg probenecid, sulfinipirazon).
Use of Apiri with food and drink
Pregnancy and lactation
pregnancy
If during treatment with Apiri patient becomes pregnant, the doctor should be notified. Apiri should not be taken during the first and second trimesters of pregnancy without consulting acre. Apiri should not be taken during the last months of pregnancy due to increased risk of complications for mother and child during childbirth.

breastfeeding
Small amounts of the active ingredient acetylsalicylic acid and its metabolites pass into breast milk. Since no adverse reactions in infants after occasional use, it is usually necessary to interrupt breastfeeding if the daily dose exceeds 150 mg. If taken in high doses (more than 150 mg daily), breastfeeding should be discontinued earlier.

Driving and using machines
No special measures required.

3. HOW TO TAKE APIRI
Always take APIRI exactly as your doctor tells you. If you are not sure, ask your doctor or pharmacist.

If not prescribed otherwise, recommends the following dosages:
For inhibition of platelet aggregation:
Unstable angina pectoris:
The daily dose ranging between 100 mg and 160 mg of acetylsalicylic acid.
For better tolerance recommended daily dose of 1 tablet Apiri (equivalent to 100 mg of acetylsalicylic acid).

Acute myocardial infarction:
The daily dose ranges between 75 mg and 300 mg of acetylsalicylic acid. Recommended daily dose of 1 tablet Apiri (equivalent to 100 mg of acetylsalicylic acid).

Prevention of reinfarction:
Recommended daily dose of 3 tablets Apiri (equivalent to 300 mg of acetylsalicylic acid).

After surgery or other interventions of the arterial blood vessels (eg ACVB, PTCA):
The daily dose ranging between 100 mg and 300 mg of acetylsalicylic acid.
For better tolerance recommended daily dose of 1 tablet Apiri (equivalent to 100 mg of acetylsalicylic acid).

Prevention of transient ischemic attacks and cerebral infarction after the onset of prodromal symptoms:
The daily dose ranges between 30 mg and 300 mg of acetylsalicylic acid.
For better tolerance recommended daily dose of 1 tablet Apiri (equivalent to 100 mg of acetylsalicylic acid).

Primary prevention of myocardial infarction:
To reduce primary myocardial infarction in people with cardiovascular risk factors, eg. diabetes mellitus, hyperlipidemia, hypertension, obesity, smoking, age, daily dose is 100 mg daily or 300 mg every other day.

Method of administration
For oral use. Tablets should be taken before meals with plenty of fluid.

If you take more dose Apiri
An overdose can be very dangerous for the elderly and for all young children (therapeutic overdose or accidental poisoning), fatal in some patients.

symptomatology:
moderate overdose
Tinnitus, hearing impairment, headache, dizziness and confusion have been reported in cases of overdose and can be controlled by reducing the dose.

Severe intoxication:
Fever, hyperventilation, ketosis, respiratory alkalosis, metabolic acidosis, coma, cardiovascular shock, respiratory failure, severe hypoglycaemia.

Emergency treatment:
Immediate admission to a specialized hospital gastric lavage, administration of activated charcoal, check the acid-base balance, alkalinity of the urine, so as to obtain a urine pH between 7.5 and 8; Phosphated alkaline diuresis must be considered when the concentration of plasma salicylate is greater than 500 mg / ml (3,6 mmol / l) in adults or 300 mg / ml (2,2 mmol / l) in children option in severe poisoning, restore lost fluids, symptomatic treatment.

If you nyakavi further questions on the use of this product, ask your doctor or pharmacist.

4. POSSIBLE SIDE EFFECTS
As with all medications, APIRI may cause side effects, although not everyone gets them.
Like all medicines, Apiri can cause side effects, although not everybody gets them.
Common: gastrointestinal disorders such as abdominal pain and micro hemorrhages.
Uncommonly reported nausea, vomiting and diarrhea.
Rare gastrointestinal bleeding and stomach ulcers and asthmatics may experience hypersensitivity reactions (shortness of breath, skin reactions).
In isolated cases are impaired hepatic and renal function, hypoglycemia and severe skin reactions (erythema ranging to exudativum multiforme).
In low-dose acetylsalicylic acid can reduce the excretion of uric acid. This can cause an attack of gout in predisposed patients.
In very rare cases, the prolonged use of Apiri might cause anemia due to occult gastrointestinal bleeding (iron deficiency anemia). If you have black stools, you should tell your doctor. Gastrointestinal bleeding can in rare cases lead to perforation.
Vertigo and tinnitus, especially in children and the elderly may be symptoms of a serious overdose.

If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

5. HOW TO STORE APIRI
Keep out of reach of children.
Apiri not use after the expiry date stated on the carton.
Apiri should be stored in its original package to protect from moisture and spotlight.
Please return left over medicine to your pharmacist. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. FURTHER INFORMATION
What does Apiri
The active substance is acetylsalicylic acid.
Each tablet contains 100 mg of acetylsalicylic acid.
Other ingredients are: microcrystalline cellulose, partially pregelatinized maize starch, stearic acid, acrylic lakes 93018359 (methacrylic acid copolymer type C, talc, titanium dioxide (E171), triethyl citrate, silica, colloidal anhydrous, sodium hydrogencarbonate, sodium lauryl sulfate).
Each pack contains 20, 30 or 150 tablets.
Not all pack sizes may be marketed.
 
 
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