AMPISULCILLIN. 1.5 g, 1 vial

AMPISULCILLIN. 1.5 g, 1 vial
€ 15.00
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Ampisulcillin be used to treat infections caused by susceptible microorganisms thereon, of the respiratory tract; in the ear, nose and throat; intra-abdominal infections, including infections of the biliary tract; skin and soft tissue .

AMPISULCILLIN. 1.5 g, 1 vial 

 
 
COMPOSITION
In 1,5 g Ampisulcillin:
Active substances : Ampicillin sodium 1,063 g, equivalent to 1,0 g Ampicillin, Sulbactam sodium 0,547 g, equivalent to 0,500 g Sulbactam.
B 3,0 g Ampisulcillin:
Active substances Ampicillin sodium 2,126 g, equivalent to 2,0 g Ampicillin, Sulbactam sodium 1,094 g, equivalent to 1,0 g Sulbactam.
 
 
PHARMACEUTICAL FORM AND CONTENTS
Powder for solution for injection - 1,5 g and 3,0 g.
Colourless glass vials of 30 ml in 1,5 g and 3,0 g, 10 pcs. in a cardboard box.
 
 
INDICATIONS
Ampisultsilin be used to treat infections caused by susceptible microorganisms thereon , of the respiratory tract ; in the ear, nose and throat ; intra-abdominal infections, including infections of the biliary tract ; skin and soft tissue; bones and joints ; of the genitourinary system. Ampisultsilin can also be applied to reduce the risk of postoperative infections in patients undergoing abdominal or gynecological surgery.
 
INFORMATION REQUIRED BEFORE USE
 
CONTRAINDICATIONS
Ampisultsilin not apply to existing allergy to penicillin or sulbactam . So the doctor should be informed of available allergy to cephalosporin antibiotics or other drugs.
 
 
SPECIAL PRECAUTIONS FOR USE
Inform the doctor if you have a known allergy to ampicillin, penicillin or cephalosporin antibiotics or other medications , kidney disease , asthma, eczema , leukemia, infectious mononucleosis ( a viral disease with angina and enlarged lymph nodes) , colitis . If an allergic reaction such as skin rash, swelling of the eyelids or face , shortness of breath , you should tell your doctor.
Applying ampisultsilin long time may lead to the development of a fungal infection , which requires appropriate treatment .
If severe and persistent diarrhea should immediately tell your doctor about it. Antibacterial agents such as ampisultsilin deplete normal development of microorganisms in the intestine , and this can lead to severe life-threatening - vashto condition known as pseudomembranous colitis . A discontinuation of treatment and appropriate measures to control the disease.
During treatment with ampisultsilin doctor may appoint performing some research , which is normal and should not bother you.
 
 
 
Interactions
Co-administration of allopurinol ampisultsilin can cause skin rashes. Mixing of some medications in the preparation in the syringe sometimes leads to a reduction in the activity in the preparation im.Sadarzhashtiyat ampicillin can reduce the activity of some of the oral contraceptive medication. The doctor should be notified about all the medicines you take, because it may affect treatment ampisultsilin .
 
 
SPECIAL WARNINGS FOR USE IN SPECIFIC PATIENT GROUPS
Patients who follow a diet with dietary salt restriction , should consider quantitative sodium content in preparation (about 71,3 mg / g).
Recommended ampisultsilin not apply to patients with infectious mononucleosis and lymphatic leukemia , acute risk because of skin rashes caused by contained in the preparation ampicillin.
In patients with renal insufficiency preparation dosed according to renal otdelyane.Upotrebata ampisultsilin in children in therapeutic doses does not lead to spitsifichni adverse reactions to them.
If you are pregnant or breast-feeding should tell their physician prior to initiating therapy with Ampisultsilin . Safety of Ampisultsilin pregnant has not been established , so it is advisable to avoid use during pregnancy unless your doctor has determined that it is necessary. Caution is advised when administering to nursing women , since ampicillin is excreted in low concentrations in human milk.
 
 
EFFECTS ON ABILITY TO DRIVE AND USE MACHINES .
Ampisultsilin not affect the ability to drive and use machines.
 
 
OTHER DATA ON INGREDIENTS
Finished dosage form contains no excipients .
 
 
INFORMATION FOR PROPER USE
 
 
DOSAGE
 
The dosage of ampisultsilin is determined by the doctor!
The usual adult dose is 1,5 g ( 1 g of ampicillin + 0,5 g sulbactam ) - 3 g ( 2 g of ampicillin + 1 g of sulbactam ) administered every 6 or 8 hours. In less severe infections that dose may be administered every 12 hours . The maximum daily dose is ampisultsilin 12 g, divided into 3 or 4, part administrations .
Daily dosage of sulbactam should not exceed 4 g.
In children, the daily dosage is 150 mg / kg, distributed in 6 or 8 hours. In neonates (up to 1 week) and premature infants ampisultsilin administered at a dose 75 mg / kg daily for 12 chasa.Pri renal dysfunction your doctor may change the dose or interval of application of ampisultsilin .
The duration of treatment can be determined by the attending physician .
 
 
HOW TO USE AND ADMINISTRATION
Ampisultsilin injected into a muscle or a vein , or is inserted into a vein by infusion.
 
 
Method of preparation:
For intramuscular administration : Ampisultsilin was dissolved in sterile water for injection or 0.5% - 1% solution of lidocaine hydrochloride, after preliminary testing on the patient's sensitivity to lidocaine . Lidocaine is contraindicated in patients with hypersensitivity to local anesthetics of the amide type.
 
The contents of the vials of 1,5 g - 3,2 ml vials and to 3 g - 6,4 ml. The resulting solution can be used within 1 hour after reconstitution. Apply deep intramuscular !
 
For intravenous use :
The formulation is reconstituted with sterile water for injection , 0.9% sodium chloride or 5% glucose , and waits until a clear solution free of air bubbles.
For direct intravenous injection to the contents of the vials of 1,5 g - 10 ml of solvent, and to 3,0 g - 20 ml of solvent . Apply slowly for at least 5-10 minutes.
 
For intravenous infusion, - the contents of the vials are dissolved in 5-10 ml of solvent , and immediately diluted as follows: 1,5 g in 50 ml of solvent and 3,0 g - in 100 ml. Infusion 15-30 minutes.
It is recommended that these solutions be implemented immediately or within 1 hour after preparation of raztvora.Da not freeze !
 
 
 
Frequency of administration
The frequency of administration is determined by the doctor!
 
DURATION OF TREATMENT
The duration of treatment is determined by the doctor! Treatment continues until the temperature falls and the disappearance of other clinical symptoms. The average duration of treatment is 5 to 14 days.
 
 
 
ACTION OF OVERDOSE
Overdose with preparation ampisultsilin immediately tell the doctor! It may be observed convulsions and other signs of damage to the central nervous system . In case of overdose, treatment should be interrupted and appropriate measures .
Ampicillin and sulbactam may be removed from the circulation by hemoadializa .
 
 
ACTION IN CASE OF RELEASE OF DOSES
In the event of a missed dose next be taken as soon as possible . This facilitates retention of the drug concentration in the blood and urine. Do not double the dose.
 
 
SIDE EFFECTS
The most common side effects with ampisultsilin are chest tightness, shortness of breath, fever, swelling of the face , eyelids, skin rashes , itching, difficulty urinating , pain and bloating, nausea , vomiting, severe diarrhea , sores in the mouth , fatigue , weakness , dizziness, headache , pain and inflammation at the injection site . Skin rashes occur in patients with infectious mononucleosis taking ampicillin , so ampisultsilin is not appropriate in such cases.
During treatment with ampisultsilin rarely observed anemia , reduced numbers of leukocytes ( white blood cells) , decreased platelet count ( platelets ) and the rise of some laboratory parameters characterizing renal and hepatic functions. Can be observed false positive reaction for glucose in the urine.
If you feel unwell or have symptoms described above or included in this information immediately inform your doctor.
 
 
STORAGE
At temperatures below 25 ° C.
Keep out of reach of children!
 
 
SHELF LIFE
Three years.
Do not use after the expiry date stated on the pack !
 
 
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