AMOKSIKLAV 875 mg . 125 mg. 20 tablets
Amoksiklav is an antibiotic and works by killing bacteria that cause infections. It contains two different medicines called amoxicillin and clavulanic acid. Amoxicillin belongs to a group of medicines called "penicillins" that can sometimes be terminated (made inactive). The other active component (clavulanic acid) does not allow this to happen ..
Amoksiklav is used in adults and children to treat the following infections:
infections of the middle ear and sinus;
respiratory tract infections;
urinary tract infections;
infections of skin and soft tissues, including dental infections;
infections of the bones and joints.
2. BEFORE YOU TAKE AMOKSIKLAV
Do not take Amoksiklav:
if you are allergic (hypersensitive) to amoxicillin, clavulanic acid, penicillin or any of the other ingredients of Amoksiklav (listed in section 6);
If you have had a serious allergic reaction (hypersensitivity) to another antibiotic. This can include a skin rash or swelling of the face or neck;
if you have ever had liver problems or jaundice (yellowing of the skin) when taking an antibiotic.
Do not take Amoksiklav if any of these things apply to you. If you are unsure, check with your doctor or pharmacist before taking Amoksiklav.
Take special care with Amoksiklav
Consult your doctor or pharmacist before taking this medicine if:
have glandular fever;
You are being treated for liver or kidney problems;
not urinate regularly.
If you are unsure whether any of these things apply to you, consult your doctor or pharmacist before taking.
In some cases, your doctor may investigate the type of bacteria that is causing your infection. Depending on the results, can provide Amoksiklav with different content of the active substance or any other drug.
Conditions you need to watch
Amoksiklav can aggravate certain existing conditions or cause serious side effects. These include allergic reactions, convulsions (seizures), and inflammatory bowel disease. You have to watch out for certain symptoms while taking this medicine to reduce the risk of problems. See 'Conditions you need to watch' in Section 4.
Blood tests or urine
If your blood tests (such as the study of the state of red blood cells or liver function tests) or urine tests, notify the doctor or nurse that you are taking Amoksiklav. This is necessary because Amoksiklav can affect the results of these types of studies.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription and herbal medicines.
If you are taking allopurinol (used for gout) with Amoksiklav, there may be more likely to have an allergic skin reaction.
If you are taking probenecid (used for gout), your doctor may decide to adjust the dose of Amoksiklav.
If drugs that prevent blood clots (such as warfarin) are taken with Amoksiklav then it may need additional blood tests.
Amoksiklav can affect the manner in which the methotrexate (a drug used to treat cancer or rheumatic diseases).
Adoption of Amoksiklav with food and drink
To minimize the likelihood of gastrointestinal intolerance, take the tablets immediately before eating.
Pregnancy and lactation
If you are pregnant, think you might be pregnant or are breast feeding, please tell your doctor or pharmacist.
Consult your doctor or pharmacist before taking any medications.
Driving and using machines
Amoksiklav can cause side effects and the symptoms may make you unfit to drive.
You should not drive or operate machinery if you feel well.
3. HOW TO TAKE AMOKSIKLAV
Always take Amoksiklav exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.
Adults and children weighing more than 40 kg
Usual dose - 1 tablet twice a day;
Higher dose - 1 tablet three times a day.
Children weighing less than 40 kg.
Children aged 6 years or less should preferably be treated with oral suspension or sachets of amoxycillin / clavulanic acid.
Ask your doctor or pharmacist when giving Amoksiklav tablets to children weighing less than 40 kg.
Patients with kidney and liver problems
If you have kidney problems, the dose can be changed. Your doctor may choose a different content of the active substance or other drug;
If you have liver problems, it may make more frequent blood tests to see how your liver is working.
How to take Amoksiklav
Take the tablets at the start of a meal or slightly before;
Separate doses evenly during the day, at least 4 hours. Do not take 2 doses in 1 hour;
Do not take this medicine more than two weeks. If you still feel bad, you should go back to the doctor.
If you take more dose Amoksiklav
If you take more than the amount Amoksiklav, the signs may include upset stomach (nausea, vomiting or diarrhea) or convulsions. Check with your doctor as soon as possible. Take container or bottle of medicine to show it to your doctor.
If you forget to take Amoksiklav
If you miss a dose, take your dose as soon as you remember. You should not take the next dose too soon, but wait at least 4 hours before taking the next dose.
If stop taking Amoksiklav
Keep taking Amoksiklav to complete the treatment, even if you feel better. You need every dose to help fight infection. If some bacteria survive, it can resume the infection.
If you have further questions about the use of this product, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Amoksiklav can cause side effects, although not everybody gets them.
Conditions which need to be careful
inflammation of the blood vessels (vasculitis) which may be visible as a raised red or purple spots on the skin, but can also affect other parts of the body;
fever, joint pain, swollen lymph nodes in the neck, armpit or groin;
swelling, sometimes of the face or mouth (angioedema), causing difficulty breathing;
Talk to your doctor immediately if you experience any of these symptoms.
Stop taking Amoksiklav.
Inflammation of the colon
Inflammation of the colon, causing watery diarrhea usually with blood and mucus, stomach pain and / or fever.
Talk to your doctor as soon as possible for advice if you get these symptoms.
Other side effects
Very common (affecting more than 1 in 10 people):
diarrhea (in adults).
Common (affects up to 1 in 10 people):
thrush (candida - a yeast infection of the mouth, vagina or skin folds);
nausea, especially at high doses. If this happens, Amoksiklav be taken before meals;
diarrhea (in children).
Uncommon (affects up to 1 in 100 people):
skin rash, itching;
rise above the skin itchy rash (hives);
Uncommon side effects that may show up in blood tests:
increase in some substances (enzymes), produced by the liver.
Rare (affects up to 1 in 1000 people):
skin rash, which may be as blisters and looks like small targets (central dark spots surrounded by a paler area, with a dark ring around the edge - erythema multiforme).
If you notice any of these symptoms, contact a doctor immediately.
Rare side effects that may show up in blood tests:
a small number of cells involved in blood clotting;
a small number of white blood cells.
Adverse reactions known (adverse reactions were observed in a very small number of people but their exact frequency is unknown).
Allergic reactions (see. Above);
Inflammatory bowel disease (see above);
Serious skin reactions:
a widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals (Stevens-Johnson), and a more severe form, causing extensive peeling of the skin (more than 30% of the body surface - toxic epidermal necrolysis);
widespread red skin rash with small pustules (bullous exfoliative dermatitis);
red, scaly rash with bumps under the skin and blisters (exanthematous pustulosis).
Talk to your doctor immediately if you experience any of these symptoms:
liver inflammation (hepatitis);
jaundice caused by an increase in bilirubin (a substance produced in the liver) which may make your skin and whites of your eyes look yellow;
inflammation of the tubes in the kidneys;
blood clot more slowly;
convulsions (in people taking high doses Amoksiklav or who have kidney problems);
black tongue which looks hairy;
staining of the teeth (in children), is usually removed with a brush.
Side effects that may show up in blood tests:
seriously reducing the number of white blood cells;
low number of red blood cells (hemolytic anemia);
crystals in urine.
If any of the side effects gets serious, or you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
5. HOW TO STORE AMOKSIKLAV
Keep this product in temperatures below 25 ° C. Store in original container, protected from moisture.
Keep out of reach of children.
Do not use Amoksiklav after the expiry date stated on the packaging. The expiry date refers to the last day of that month.
Medicines should not be disposed of in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment
6. ADDITIONAL INFORMATION
The active substances are: amoxicillin and clavulanic acid.
Each tablet contains 875 mg Amoksiklav amoxicillin in the form of amoxycillin trihydrate and 125 mg of clavulanic acid in the form of potassium clavulanate.
Each tablet contains 25 mg of potassium.
Other ingredients are:
Core: anhydrous colloidal silicon dioxide, crospovidone, croscarmellose sodium, magnesium stearate, microcrystalline cellulose.
Film-coating: hydroxypropylcellulose, ethylcellulose, polysorbate 80, triethyl citrate, titanium dioxide, talc, E171.
Amoksiklav looks like and contents of the pack
White to off-white oval tablets with bevelled edges, scored with 875/125 inscription on one side and AMC the other side.
Amoksiklav 875 mg / 125 mg is available in boxes with two or four blisters each of which contains 5 film-coated tablets (10 or 20 tablets).