AMEOLIN. 100 mg. 10 tablets

AMEOLIN. 100 mg. 10 tablets
€ 12.00
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For short-term relief of pain:
  Rheumatic diseases;
  osteoarthritis;
  Postoperative conditions accompanied by pain and inflammation (including dentistry);
  Acute injuries;

AMEOLIN. 100 mg. 10 tablets

 
 
One tablet contains nimesulide 100 mg.
 
* Indications
 
For short-term relief of pain:
 
o Rheumatic diseases;
o Osteoarthritis;
o Postoperative conditions accompanied by pain and inflammation (including dentistry);
o acute trauma;
o Dysmenorrhea.
 
 
 
* Dosage
Orally.
Adults and children over 15 years - the recommended daily dose is 100 mg 2 times a Day. The dose may be increased - 200 mg in the morning and evening for no more than 1-3 days. The maximum daily dose of 400 mg should not be exceeded. The duration of therapy is determined by the doctor, but does not exceed 7 days.
Patients of '65 - no need for dose adjustment.
 
 
* Contraindications
 
Hypersensitivity to the active substance or to any of the excipients;
Hypersensitivity to salicylates or other NSAIDs;
o Impaired hepatic function;
o Renal failure;
o Active or recurrent gastro-duodenal ulcer;
o History of gastrointestinal bleeding;
o Severe bleeding disorders;
o Children under 15 years of age;
o Pregnancy and lactation.
 
 
* Special warnings
o Patients suffering from bronchial asthma, chronic rhinitis, chronic sinusitis or nasal polyps, have an increased risk of allergy in the use of NSAIDs. The use of Nimesulide in these patients can cause an asthma attack.
 
o Gastrointestinal bleeding, ulceration or perforation, including fatalities, have been reported with the use of all NSAIDs at anytime during treatment, with or without warning symptoms or a previous history of serious incidents from the gastrointestinal tract.
 
o Relatively high risk exists in elderly patients, patients on diet with concomitant anticoagulant therapy in individuals with alcohol abusers, smokers. These patients should commence treatment with NSAIDs at the lowest possible dose, as considered necessary by the addition of protective agents (eg misoprostol or proton pump inhibitors). This behavior is recommended in cases of concomitant use of corticosteroids, anticoagulants, antiplatelet agents, selective inhibitors of serotonin reuptake.
 
o Caution is required in patients with other gastrointestinal diseases such as ulcerative colitis and Crohn's Crohn, which can be exacerbated with the use of NSAIDs.
 
o Treatment of Nimesulide is not recommended for fast progressive rheumatic or post-traumatic conditions, which lead to the disabling of the patient.
 
o If signs of liver disorders such as anorexia, nausea, vomiting, pain in the abdomen, fatigue, dark urine, jaundice, it is necessary to trace the liver laboratory parameters. A change in liver function tests, treatment is terminated. In such patients, the reuse of Nimesulide is contraindicated.
 
o Serious skin reactions, including fatalities, occurred very rarely with the use of NSAIDs relate to cases of exfoliative dermatitis syndrome, Stevens-Johnson, toxic epidermal necrolysis. The drug should be discontinued at the first appearance of skin or other signs of hypersensitivity.
 
o Particular caution should be used Nimesulide in patients with a history of hypertension and / or heart failure because of the risk of fluid retention and swelling.
 
o During treatment with Nimesulide control is necessary in renal function in patients with chronic heart failure, diuretic therapy after surgery with hypovolemia.
 
o Nimesulide is appointed with caution and under medical supervision in patients with coagulopathies.
 
o In case of visual disturbances Nimesulide treatment should be immediately discontinued.
 
o In women of reproductive age, the possibility of suppressing fertility with the use of the product.
 
o Ameolin contains the excipient lactose, which can be dangerous for people with glucose / galactose malabsorption.
 
 
 
* Drug Interactions
o The concomitant use of salicylates and other NSAIDs with nimesulide due to an increased risk of gastrointestinal ulceration.
o There is a high risk of bleeding during concomitant treatment with nimesulide and oral anticoagulants. It is necessary to monitor the prothrombin time in the first days of treatment.
o Heparin (parenteral): increased risk of bleeding.
Ticlopidine o Increased risk of bleeding due to the synergistic effect.
o Methotrexate (at doses above 15 mg / week): Nimesulide it shifts from plasma proteins and increase its level in plasma.
o Lithium: NSAIDs increase plasma lithium levels and decreased renal clearance. Increased risk of lithium toxicity.
o Furosemide and thiazide diuretics: NSAIDs decrease the natriuretic effect. When concomitant treatment with nimesulide and furosemide is necessary to monitor the water-salt balance and diuretic effect of furosemide.
o Nimesulide reduces the antihypertensive effect of ACE-inhibitors.
o Concomitant treatment with nimesulide reduces the antihypertensive effect of beta-blockers.
o Cyclosporine: There is a high risk of enhanced nephrotoxic effect when used together with nimesulide, particularly in elderly patients.
 
 
Pregnancy and lactation
Nimesulide is contraindicated during pregnancy and lactation.
 
* Adverse Drug Reactions
 
o Gastrointestinal tract - nausea, vomiting, epigastric pain and abdomen, diarrhea, constipation, gastro-duodenal ulcer, bleeding from the gastrointestinal tract.
o hepatobiliary tract - asymptomatic elevations of hepatic enzymes, acute hepatitis, liver failure.
o Skin and appendages - Skin rashes, pruritus, urticaria.
o Respiratory system - difficulty breathing, asthma attacks, especially in patients with hypersensitivity to NSAIDs.
o Nervous system - fatigue, weakness, dizziness, headache, drowsiness.
o vision - visual impairment.
o Other - angioneurotic edema.
 
* Formulation and packaging
Tablets.
10 pieces in a blister, 1 or 2 blisters in a box.
 
 
 
€ 12.00
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